Development regeneration. Medical search. Frequent questions

The meeting, organized by Elisa Martí (IBMB-CSIC, Barcelona, Spain), Jonas Muhr (Karolinska Institutet, Stockholm, Sweden) and Kate Storey (University of Dundee, UK), brought together international researchers interested in spinal cord development and those who are developing strategies to restore the function of the spinal cord in pathological situations using regeneration of the damaged tissue, including controlled cell replacement. (biologists.com)
It is thought from many standpoints, such as signaling and patterning that tissue regeneration may recapitulate various processes that occur during initial development. (manchester.ac.uk)
to what extent do the processes of early embryonic development and tissue regeneration share or differ in metabolic states and how are these regulated? (manchester.ac.uk)
Bone regeneration using electrospun nanofibers' implant has the following objectives: bone neoformation induction with rapid healing, reduced postoperative complications, and improvement of bone tissue quality. (hindawi.com)
The clinical purpose of these methods is the reparation or guided regeneration of damaged tissue, in our case, jaw bone affected by genetical diseases. (hindawi.com)
Thus, the strategy of functionalization of nanofibers by nanoreservoirs of BMP-2 or BMP-7 showed a great efficiency for bone regeneration and increased the differentiation of MSCs (mesenchymal stem cells), accelerating the tissue regeneration in vivo [ 9 , 10 , 13 , 14 ]. (hindawi.com)
Thus, it has been shown that early EPCs release cytokines that promote tissue regeneration and neovasculogenesis, whereas late EPC and endothelial colony forming cells (ECFCs) contribute to the formation of blood vessels and stimulate tube formation. (intechopen.com)
Tissue regeneration is a fascinating phenomenon, but the cellular and molecular mechanisms underlying regeneration remain incompletely understood. (silverchair.com)
Recent advances in live imaging and genetics of mammalian division, movement and cell differentiation leading to development which integrate observations of biochemical tissue formation [14 ]. (lu.se)
Twenty-five years of recombinant human growth factors rhPDGF-BB and rhBMP-2 in oral hard and soft tissue regeneration. (bvsalud.org)
Recombinant human growth factor applications in oral hard and soft tissue regeneration have been progressively researched over the last 25 years. (bvsalud.org)
The present review explores and depicts the current applications, outcomes, and evidence-based clinical recommendations of rhPDGF-BB and rhBMPs for oral tissue regeneration . (bvsalud.org)
In recent years, tissue engineering has evolved considerably, due to the problems in the biomedical area concerning tissue regeneration therapies. (bvsalud.org)
Moreover, sterilization strategies of scaffold are a crucial step for its application in tissue regeneration, however, the sterilization process have to maintain the structural and biochemical properties of the scaffold. (bvsalud.org)
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. (bvsalud.org)

Our professional team comprises over 100 specialist town planners and surveyors, development consultants, urban designers & masterplanners, town centre regeneration experts, economists, compulsory purchase order (CPO) / land assembly advisers, transport & infrastructure specialists, and dedicated public sector consultants. (lsh.ie)
Largescale infrastructure projects and town centre regeneration have become vital, bringing the management of CPOs into the spotlight. (lsh.ie)
Sir Michael Lyons, chair of ECF, said: "We welcome this opportunity to be a part of an ambitious programme of town centre regeneration, and to play an important role in the long-term growth and ambition of Stockport. (placenorthwest.co.uk)

More generally, MSc Urban Regeneration and Development graduates are popular with employers, particularly in consultancy, where the ability to analyse and propose policies and implement strategies is vital. (manchester.ac.uk)
6. An Outline of Post-War Dutch Urban Regeneration Policy. (routledge.com)
8. Urban Regeneration Policies in Barcelona: Periods, Territories and Agents. (routledge.com)
Among the various urban imaginaries, the "Green City" has become subject of global urban regeneration activities, often aided by deindustrialization ( 4 ). (frontiersin.org)
The purpose of this literature review is to identify urban regeneration projects that aim for physical improvements through the provision of urban blue spaces in deprived communities 1 . (frontiersin.org)

Work on the demolition of the former Debenhams building is currently underway, with construction work on the first phase of development set to commence in 2020. (derby.gov.uk)

In this Review, we discuss recent work that reveals the changes in white matter with ageing and neurodegenerative disease, how this relates to microglia dynamics during myelin damage and regeneration, and factors that influence the regenerative functions of microglia. (nature.com)
This volume is therefore essential reading for molecular, cell, and developmental biologists studying regeneration in animals, as well as for all interested in the development of regenerative therapies for clinical application. (cshlpress.com)
Here, Development has collated a series of articles showcasing some of the most recent advances in regenerative biology. (silverchair.com)
Leigh lab is focused on understanding how the immune system is able to facilitate regeneration in highly regenerative species. (lu.se)
This interdisciplinary approach employs concepts and techniques from immunology and regenerative biology as well as cutting edge 'omics based approaches to uncover immune system-derived requirements for scar-free healing and regeneration. (lu.se)

if human embryonic, only NIH approved human embryonic stem cell lines may be used) as a source for making pancreatic islets, and to determine the basic mechanisms underlying beta cell regeneration in the adult as a basis for producing new cellular therapies for diabetes. (nih.gov)
Given the lack of approved therapies targeting myelin maintenance or regeneration, it is imperative to understand the mechanisms by which microglia support and restore myelin health to identify potential therapeutic approaches. (nature.com)

Externally applied sialidase converted GD1a ganglioside to GM1 and rescued axon regeneration in CNS axons and in PNS axons after Neu3 sialidase blockade. (jneurosci.org)
In this paper, we examine Neu3 sialidase action on axonal gangliosides and resultant axon regeneration, and we assess whether these mechanisms help to explain the different regeneration capacities of CNS and PNS axons. (jneurosci.org)

Retinal regeneration refers to the restoration of vision in vertebrates that have suffered retinal lesions or retinal degeneration. (wikipedia.org)
The two most well-studied mechanisms of retinal regeneration are cell-mediated regeneration and cellular transplantation. (wikipedia.org)
This ability combined with the considerable similarity between teleost and mammalian retinal structure makes zebrafish an attractive model for the study of retinal regeneration. (wikipedia.org)
Retinal regeneration in zebrafish is mediated by Muller glia, which dedifferentiate into stem-like cells and proliferate into neural progenitor cells in response to retinal damage. (wikipedia.org)
Several proteins and signaling pathways have been described and characterized in the process of retinal regeneration. (wikipedia.org)
Other approaches to retinal regeneration involve cellular transplantation treatments. (wikipedia.org)

Fig. 3: Mechanisms regulating microglial function during myelin regeneration: intrinsic versus extrinsic influences. (nature.com)
Although muscle regeneration has been deeply investigated in the past decades, most studies were centered on mechanisms involving other cells, including muscle stem cells, which are required upon extensive muscle damage. (scitechdaily.com)

Now, we showed a functional relevance for this phenomenon in adulthood during cellular repair and regeneration," says Edgar R. Gomes, group leader at the Instituto de Medicina Molecular and Professor at Faculdade de Medicina da Universidade de Lisboa, who co-led the study. (scitechdaily.com)

Journal Article] Transplantation of Thy1+ cells accelerates liver regeneration by enhancing the growth of small hepatocyte-like progenitor cells via IL17RB signaling. (nii.ac.jp)
The contributors discuss the dramatic molecular and cellular changes that occur when a regeneration program is initiated, the progenitor cells and morphogenic signals involved, the formation of a blastema, the roles of reprogramming and polyploidy, the diversity of cell fates, the integration of new structures with existing body parts, and our current understanding of why some structures are more resistant to regeneration than others. (cshlpress.com)
The regeneration of mammalian peripheral nerves after injury requires glial cells called Schwann cells (SCs), which dedifferentiate to a progenitor-like state to direct the regeneration process. (silverchair.com)

Residual pools of adult stem cells are hypothesized to be the source of lung regeneration and repair. (nih.gov)

More information on the signaling pathways involved is required before Muller glia mediated regeneration will be a viable treatment method for restoring vision in mammalian retinas. (wikipedia.org)

Although microglia have been increasingly implicated in contributing to the pathology that underpins neurological dysfunction and disease, they also have crucial roles in neurological homeostasis and regeneration. (nature.com)

The latest advances in the field of spinal cord development and its regeneration following damage were discussed at a recent EMBO workshop 'Spinal cord development and regeneration' in Sitges, Spain (October, 2014), highlighting the use of direct visualization of cellular processes, genome-wide molecular techniques and the development of methods for directed stem cell differentiation and regeneration. (biologists.com)
Thus, we find that endogenous Rspo3 signaling is a critical determinant of cellular fate within the crypt and stimulates rapid recruitment of differentiated cells for epithelial wound healing and crypt regeneration through induction of Wnt signaling. (nature.com)
William Roman, main author of the study and researcher at iMM and UPF Barcelona, explains: "Even in physiological conditions, regeneration is vital for muscle to endure the mechanical stress of contraction, which often leads to cellular damage. (scitechdaily.com)

Hackney Walk regeneration will create a new focal point for UK fashion in the heart of East London's regeneration. (ftsquared.com)

Nanofibrous and microporous membranes are very suitable to promote bone regeneration as a mimetic extracellular matrix. (hindawi.com)

Your resource for economic development jobs in the US. (geographyjobs.com)
Check back often for more Economic Development jobs. (geographyjobs.com)
You will discover how planning, regeneration and development practices can help tackle climate change and deliver appropriate social, environmental and economic development proposals, using a fantastic range of live projects across Northern Ireland and beyond. (ulster.ac.uk)
7. Local Economic Development, Urban Change and Regeneration in Turkey. (routledge.com)
In the 21st century, a main challenge for cities will be to unlock their transformative power for ensuring sustainable urbanization ( 1 ), while concurrently tackling questions of economic development and social justice ( 2 ). (frontiersin.org)

Discover the fascinating ways in which the planning system, regeneration practices and development processes work. (ulster.ac.uk)
These cells can be differentiated into mature endothelial cells, which are involved in processes of angiogenesis and vessel regeneration. (intechopen.com)
Written by experts working in the USA, Holland, Greece, Jamaica, Turkey, Spain, Trinidad and the Czech Republic, this book seeks to locate the issue of regeneration in a context which will enable the reader to reflect upon practices which are 'local' but are shaped by international processes. (routledge.com)

Microglia across the lifespan: from origin to function in brain development, plasticity and cognition. (nature.com)
We focus on the lineage plasticity of hepatocytes and cholangiocytes during development and regeneration. (nii.ac.jp)
SC fate plasticity during regeneration is limited: mSCs can contribute to non-myelinated mSCs and vice versa. (silverchair.com)
The remarkable transition from quiescence to regeneration in peripheral nerves is thus orchestrated not by a resident stem cell population but mature cells with proliferative capacity and limited fate plasticity. (silverchair.com)

That is why on each of our courses within the Belfast School of Architecture and the Built Environment you will learn about the UN Sustainable Development Goals and the contribution you can make now, and as a graduate in the Built Environment. (ulster.ac.uk)
Learn how you, as a future professional, can deliver the United Nations' Sustainable Development Goals (SDGs) for creating sustainable places and communities. (ulster.ac.uk)
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. (lu.se)
On 1st January 2016, the 17 Sustainable Development Goals (SDGs) of the Agenda officially came into force. (lu.se)
The Encyclopedia of the UN Sustainable Development Goals comprehensively addresses the SDGs in an integrated way. (lu.se)

The recent EMBO workshop 'Spinal cord development and regeneration' held in Sitges, a pleasant Spanish Mediterranean town, highlighted the spinal cord as a complex and accessible model system in which to analyse neural circuit formation and repair. (biologists.com)

It speaks volumes about the strength of the opportunity in Stockport that, within just one year of starting our search for a new development partner for Stockport 8, we have secured a long-term joint venture with ECF," he said. (placenorthwest.co.uk)
Therefore, there is an increasing need to search for integrated solutions to make development more sustainable. (lu.se)

Please submit work closely aligned with the themes of Extraction, Restoration, and Regeneration. (artisttrust.org)

This includes regulation of the maintenance and regeneration of myelin, the membrane that surrounds neuronal axons, which is required for axonal health and function. (nature.com)

Samples were regenerated using active and passive conditions to evaluate regeneration rates and the potential impact of regeneration at the vehicle level. (sae.org)
In order to evaluate the role of environmental change for human activity, evidence for coinciding shifts in palaeoclimate records and their potential implication for human-environment interactions are discussed and generally support the idea that environmental changes played an important role for the cultural development during the Neolithic in Northern Germany. (lu.se)
This study was conducted to evaluate the effects of a diesel particulate filter (DPF) regeneration process on the concentrations and size distributions of aerosols in an underground mine. (cdc.gov)
Then, to translate the knowledge from Paper I and III, a new model that could use human samples needed to be found, this is Paper II, in which we developed a bioengineered model for salivary gland disease that can be used to evaluate regeneration and test pharmaceutical trials (like EV therapy). (lu.se)

5. Regeneration or Redevelopment? (routledge.com)
Sanctuary Housing are hoping that the redevelopment of the Talbot Gardens area will expand and complement the regeneration of the adjacent Clarion housing scheme. (plymouth.gov.uk)
By the end of the redevelopment process, PCC will have supported the public infrastructure development in the North Prospect Regeneration area. (plymouth.gov.uk)

I will show how cell surface mechanics in particular impacts cell signalling that is instructive for cell fate choice, both in stem cells and development. (sheffield.ac.uk)
Upon Lgr5 + cell depletion, these cells are recruited to contribute to crypt regeneration. (nature.com)
Chemical injury induced by DSS leads to a loss of both Lgr5 + cells and Axin2 + cells and epithelial regeneration is driven by Axin2 − cells, including differentiated Krt20 + surface enterocytes. (nature.com)
Regeneration requires stromal Rspo3, which is present at increased levels upon injury and reprograms Lgr5 − but Lgr4 + differentiated cells. (nature.com)
One of the most fascinating things in these cells is the movement during development of their nuclei, the biggest organelles inside the cell, but the reasons why nuclei move are largely unknown. (scitechdaily.com)

11. International Perspectives on Regeneration Management: Common Themes and the Making of Value. (routledge.com)
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology explores the biological basis of regeneration in diverse animal species and how this knowledge can be applied therapeutically in humans. (cshlpress.com)

Several clinical studies assessed the outcomes of rhBMP-2 in diverse clinical applications for implant site development and bone augmentation. (bvsalud.org)
[ 2 ] With the increasing prevalence of obesity in pregnancy and GDM, [ 3 ] it has become increasingly important to develop evidence-based clinical interventions that prevent the development of GDM and minimize excess GWG. (medscape.com)

Delivering transformational and commercially viable regeneration and infrastructure projects on complex sites that meet place-making, Net Zero, and social value objectives, is not easy. (lsh.ie)

The Woolf Institute has an opening for a part-time role in its Development Office supporting funding applications towards its outreach projects, for programmes such as Diversity in End of Life Care . (fbrn.org.uk)
This paper examines the diversity, regeneration status, socio-economic importance of the forests in Kaja Araba and Tula forests, southwestern Ethiopia. (scirp.org)

The council and the Mayoral Development Corporation have selected English Cities Fund to deliver the next phase of the 130-acre town centre west scheme. (placenorthwest.co.uk)
An affordable housing development scheme identified in the adopted Joint Local Plan. (plymouth.gov.uk)

Architectural regeneration encompasses the collective activities of reusing, adapting and evolving existing buildings within an urban or rural context in ways that recognise the impacts these decisions and interventions have on the regeneration of a place, and that are underpinned by the principles of environmental, social and cultural sustainability. (brookes.ac.uk)
Although greening interventions are widespread on urban development agendas to reach environmental and social goals, it can actually be observed that cities worldwide are in the process of also becoming blue . (frontiersin.org)
The development of type 2 diabetes through intensive lifestyle interventions can be reduced by 58% within 4 years in nonpregnant women who have previously had GDM. (medscape.com)

This PA is intended to stimulate the application of advances made in developmental biology, stem cell biology, and diabetes to develop new strategies for diabetes therapy, either through cell replacement or regeneration. (nih.gov)
The absence of interdental papilla as a result of the periodontal disease development or of the periodontal therapy used is a situation that leads to aesthetic, phonetic and food impaction problems. (bvsalud.org)

Here, we explore the dynamics of crypt regeneration and Wnt/Rspo signaling in the colon in the context of crypt injury. (nature.com)
The research has considered the theoretical context of architectural regeneration and its links to theories of anthropology of architecture, conservation and design. (brookes.ac.uk)
1. Context to Globalisation and Regeneration. (routledge.com)

In recent years, existing regeneration methodologies have been improved and new approaches have been devised. (illinois.edu)
The use of electrochemical methods has allowed cofactor regeneration for monooxygenases and natural or engineered whole-cell systems provide alternatives to approaches relying on purified enzymes. (illinois.edu)

But in mammals, including humans, some tissues (e.g., heart muscle) are more resistant to regeneration. (cshlpress.com)

Papillary regeneration aims to fill the black spaces that occur in interproximal surfaces, one of the most complex cosmetic procedures to be performed among periodontal surgeries. (bvsalud.org)

Balfour Beatty, the international infrastructure group, today announces it has signed a development agreement with the London Legacy Development Corporation to invest and construct the new East Wick and Sweetwater housing development project. (balfourbeatty.com)
Leo Quinn, Balfour Beatty Group Chief Executive said: "This project marks our entry as an investor and developer into the UK's regeneration and housing sector. (balfourbeatty.com)
You will develop wide-ranging skills for creating sustainable development and healthy places by learning about environmental protection, planning law and practice, urban design, stakeholder engagement, housing market analysis, financial appraisals of property development and leadership for managing change. (ulster.ac.uk)
Housing regeneration is an essential part of our plans for housing . (plymouth.gov.uk)
Our teams are working with the Housing Associations to help with regeneration projects. (plymouth.gov.uk)
The Housing Delivery team work with its partners to keep these development projects/proposals on track. (plymouth.gov.uk)

Cllr Mark Hunter, Leader of Stockport Council, said: Between Weir Mill and Stockport Interchange, this new [Stockport 8] neighbourhood will complement our other major developments, as well as deliver new jobs and contribute to a vibrant town centre. (placenorthwest.co.uk)

The results on the importance value index (IVI) and DBH class distributions show that the species with low IVI value and poor regeneration status need to be prioritized for conservation. (scirp.org)

The Regeneration of Urban Blue Spaces: A Public Health Intervention? (frontiersin.org)
Despite blue spaces prevailing on urban development agendas across the world, little investigation has been done whether and how the regeneration of such spaces is used as a (community-based) public health intervention. (frontiersin.org)
The various values ascribed to the regeneration of blue spaces include environmental and social aspirations (e.g., improved eco-health, enhanced urban aesthetics and quality of urban life), and increased economic prospects ( 7 ). (frontiersin.org)

Work on the final phase of the regeneration is now underway. (plymouth.gov.uk)

The degree will provide you with the academic knowledge and professional skills for employment in the private (consultancy, development industry) and public (local authorities, development agencies) sectors. (manchester.ac.uk)

This book was born out of the need to 'capture' the experience and understanding of the regeneration management process that is neither UK centric nor centred exclusively on urban areas. (routledge.com)
However, whether an additional stem cell population contributes to injury-induced SCs, and how plastic SC fate is during the regeneration process, have remained controversial issues. (silverchair.com)

With high quality research and excellent teaching, highlighted by our 96% student satisfaction rate (Unistats), you will be studying at a top university for planning, regeneration and development. (ulster.ac.uk)
In this study, we found an alternative mechanism of regeneration that is muscle cell autonomous," says Pura Muñoz-Cánoves, group leader at the University Pompeu Fabra, and study leader. (scitechdaily.com)

The regeneration of the Becketwell area of the city is expected to bring numerous benefits to the city, including a repopulation of both office workers and residents to the city centre which will help boost activity outside of traditional retail hours. (derby.gov.uk)

As well as proving an accessible review of the theoretical literature on globalisation and its impact upon managing regeneration initiatives, this book also illustrates these theoretical debates with specific examples which provide insight to both urban and rural developments. (routledge.com)

The threats posed by global development trends and local driving forces such as climate change and socio-spatial segregation call for a reinvention of cities and promote the vision of an advanced city model: one that is healthy, lively, safe, and sustainable ( 3 ). (frontiersin.org)

I look forward to continuing our strong partnership with the London Legacy Development Corporation to ensure that commitments made as part of the London 2012 Games are delivered by not only creating new communities but also new jobs, and apprenticeships for young people wanting to join the growing infrastructure sector. (balfourbeatty.com)

Signals that regulate epithelial regeneration upon stem cell injury are largely unknown. (nature.com)

Spain) and published on October 15, 2021, in the scientific journal Science describes a new mechanism for muscle regeneration after physiological damage relying on the rearrangement of nuclei. (scitechdaily.com)

In particular, a research project for Design for London and the London Development Agency into the future of the city's high streets laid the foundations for many of their subsequent projects, and cemented their interest in slightly forgotten parts of outer London with little obvious potential for regeneration. (iconeye.com)
The modestly perchlorate-impacted fraction of the regenerant from each event was re-used in subsequent regeneration events without further treatment. (serdp-estcp.org)
The incidence of HCC is highest in Asia and Africa, where the endemic high prevalence of hepatitis B and hepatitis C strongly predisposes to the development of chronic liver disease and subsequent development of HCC. (medscape.com)

These different nanofiber scaffolds with nanoreservoirs are efficient proregenerative biomimicking implants for bone regeneration. (hindawi.com)

To facilitate model development, single oraldose pharmacokinetic studies were conducted in rats (l - 100 mglkg) and the kinetics of DZN and IMHP as well as the extent of plasma ChE and RBC and brain acetylcholinesterase (AChE) inhibition were determined. (cdc.gov)

Our research into the codes and cell changes associated with normal development and aging, and distinguishing them from those linked to disease and disability, will lead to new strategies to protect our health. (sbpdiscovery.org)
The importance of technologies (e.g., single-cell RNA-seq) that have been instrumental in deciphering various aspects of regeneration in recent years is emphasized throughout. (cshlpress.com)
Keep up with the Node 'Lab meeting' posts as the platform regularly highlights development and stem cell biology labs from across the globe and showcases research and researchers from the community. (silverchair.com)

Crucial steps in spinal cord development and repair strategies. (biologists.com)
We recognise the need to provide our clients with clear, up to date, discerning advice, in addition to effective development solutions and strategies that minimise exposure to costs and risk. (lsh.ie)

These goals cover the three dimensions of sustainable development: economic growth, social inclusion and environmental protection. (lu.se)

Anatomy73

Organisms29

Diseases14

Chemicals and Drugs45

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Phenomena and Processes43

Disciplines and Occupations2

Technology, Industry, Agriculture7

Information Science1

Tissue15

Town centre regeneration3

Urban Regeneration5

20201

Regenerative5

Therapies2

Axon regeneration2

Retinal regeneration6

Mechanisms2

Repair and regeneration1

Progenitor3

Lung regeneration1

Mammalian1

Homeostasis and regeneration1

Cellular3

London's1

Extracellular matrix1

Economic Development5

Processes3

Plasticity4

Sustainable Development Goals5

Neural1

Search2

Restoration1

Regulation1

Evaluate4

Redevelopment3

Cells5

Perspectives2

Clinical2

Viable1

Diversity2

Scheme2

Interventions3

Therapy2

Context3

Approaches2

Humans1

Occur1

Housing6

Complement1

Conservation1

Spaces3

Underway1

Sectors1

Process2

University2

Residents1

Theoretical1

Climate change1

Sector1

Signals1

Mechanism1

Subsequent3

Bone1

Facilitate1

Cell3

Strategies2

Goals1