Development degradation tumor suppressor proteins. Medical search. Frequent questions

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Anatomy16

Cell Line, Tumor Cell Line Tumor Cells, Cultured HeLa Cells Cells, Cultured Fibroblasts Cell Nucleus HCT116 Cells Cell Line, Transformed COS Cells NIH 3T3 Cells Cytoplasm HEK293 Cells Epithelial Cells 3T3 Cells Keratinocytes

Organisms8

Mice, Knockout Mice, Nude Mice, Inbred C57BL Mice, Transgenic Mice, Inbred BALB C Papillomaviridae Adenoviridae Drosophila

Diseases28

Cell Transformation, Neoplastic Neoplasms Kidney Neoplasms Breast Neoplasms Wilms Tumor Osteosarcoma Carcinoma, Renal Cell Neoplasms, Experimental Neurofibromatosis 2 Adenocarcinoma von Hippel-Lindau Disease Liver Neoplasms Brain Neoplasms Colonic Neoplasms Carcinoma, Hepatocellular Skin Neoplasms Carcinoma, Squamous Cell Retinoblastoma Neoplasm Metastasis Lung Neoplasms Disease Progression Carcinoid Tumor Glioblastoma Mammary Neoplasms, Experimental Ovarian Neoplasms Neovascularization, Pathologic Neuroendocrine Tumors Disease Models, Animal

Chemicals and Drugs96

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Nuclear Proteins Ubiquitin-Protein Ligases Neurofibromin 2 DNA-Binding Proteins Transcription Factors Adenomatous Polyposis Coli Protein Cyclin-Dependent Kinase Inhibitor p16 Cell Cycle Proteins Proteasome Endopeptidase Complex Proto-Oncogene Proteins PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p21 Ligases RNA, Messenger Proteins Neoplasm Proteins Cyclins Repressor Proteins Ubiquitin E2F Transcription Factors Tumor Markers, Biological Carrier Proteins Protein-Serine-Threonine Kinases Recombinant Fusion Proteins RNA, Small Interfering E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins Oncogene Proteins, Viral Transcription Factor DP1 Papillomavirus E7 Proteins Ubiquitins Trans-Activators WT1 Proteins Retinoblastoma-Binding Protein 1 Tumor Necrosis Factor-alpha DNA Primers Membrane Proteins Retinoblastoma-Like Protein p107 Recombinant Proteins Hypoxia-Inducible Factor 1, alpha Subunit DNA, Neoplasm DNA Intracellular Signaling Peptides and Proteins Cyclin-Dependent Kinases Cysteine Endopeptidases Phosphoric Monoester Hydrolases Retinoblastoma-Like Protein p130 Apoptosis Regulatory Proteins Phosphoproteins Antigens, Polyomavirus Transforming Multienzyme Complexes Cytoskeletal Proteins Adaptor Proteins, Signal Transducing beta Catenin Drosophila Proteins Neurofibromin 1 Adenovirus E1A Proteins BRCA1 Protein DNA, Complementary Adenovirus E1B Proteins Luciferases Adenovirus E4 Proteins Proto-Oncogene Proteins c-myc Antineoplastic Agents Protein Isoforms Cyclin-Dependent Kinase Inhibitor p27 MicroRNAs Cyclin-Dependent Kinase 4 Suppressor Factors, Immunologic RNA, Neoplasm Hypoxia-Inducible Factor 1 Serine Proto-Oncogene Proteins c-bcl-2 Oncogene Proteins Enzyme Inhibitors Multiprotein Complexes Cullin Proteins Proto-Oncogene Proteins c-akt Cyclin D1 Ubiquitin Thiolesterase Cyclin-Dependent Kinase 2 Ubiquitin-Conjugating Enzymes bcl-2-Associated X Protein Glutathione Transferase Protein Kinases Cadherins Microtubule-Associated Proteins Carcinogens NF-kappa B CDC2-CDC28 Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Transfection Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Models, Biological Tumor Burden Immunohistochemistry Immunoblotting Precipitin Tests Immunoprecipitation Polymerase Chain Reaction Neoplasms, Experimental Transplantation, Heterologous Two-Hybrid System Techniques Cloning, Molecular Microscopy, Fluorescence Flow Cytometry Gene Expression Profiling Neoplasm Transplantation DNA Mutational Analysis Chromatin Immunoprecipitation Chromosome Mapping Fluorescent Antibody Technique Xenograft Model Antitumor Assays Mammary Neoplasms, Experimental Mutagenesis, Site-Directed Oligonucleotide Array Sequence Analysis Sequence Alignment Blotting, Northern Disease Models, Animal Immunoenzyme Techniques

Phenomena and Processes76

Genes, Tumor Suppressor Mutation Protein Binding Genes, p53 Apoptosis Gene Expression Regulation, Neoplastic Cell Cycle Amino Acid Sequence Transfection Signal Transduction Base Sequence Genes, Suppressor Promoter Regions, Genetic Phosphorylation Cell Proliferation DNA Damage Transcription, Genetic Cell Division Down-Regulation Protein Structure, Tertiary Transcriptional Activation Binding Sites Gene Silencing RNA Interference Gene Expression Regulation Ubiquitination Suppression, Genetic Gene Deletion DNA Methylation Loss of Heterozygosity G1 Phase Cell Aging Proteolysis Genes, Retinoblastoma Ultraviolet Rays Cell Survival Genes, Neurofibromatosis 2 Gene Expression Time Factors Phenotype Oncogenes Sequence Homology, Amino Acid Plasmids Up-Regulation Genes, Reporter Protein Stability Cell Movement Protein Processing, Post-Translational Protein Transport Genes, APC Genes, p16 Cell Differentiation Amino Acid Motifs S Phase Genes, ras Enzyme Activation Sequence Deletion Acetylation Active Transport, Cell Nucleus Alleles Mutagenesis Gamma Rays Genes, Wilms Tumor Point Mutation DNA Repair Cell Hypoxia Kinetics Genetic Vectors Exons Tumor Microenvironment Cell Cycle Checkpoints Dose-Response Relationship, Drug CpG Islands Mitosis Cell Death Protein Biosynthesis

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Cell Line, Tumor Proto-Oncogene Proteins c-mdm2 Molecular Sequence Data Mutation Protein Binding Nuclear Proteins Genes, p53 Apoptosis Ubiquitin-Protein Ligases Cell Line Gene Expression Regulation, Neoplastic Neurofibromin 2 DNA-Binding Proteins Transcription Factors Adenomatous Polyposis Coli Protein Cell Cycle Amino Acid Sequence Transfection Tumor Cells, Cultured Cyclin-Dependent Kinase Inhibitor p16 Signal Transduction Cell Cycle Proteins Proteasome Endopeptidase Complex Base Sequence Proto-Oncogene Proteins Genes, Suppressor PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p21 Promoter Regions, Genetic Phosphorylation Cell Transformation, Neoplastic Cell Proliferation Ligases DNA Damage Transcription, Genetic RNA, Messenger Proteins Cell Division Neoplasm Proteins Down-Regulation Protein Structure, Tertiary Neoplasms Cyclins Blotting, Western Repressor Proteins Ubiquitin E2F Transcription Factors Transcriptional Activation Tumor Markers, Biological HeLa Cells Binding Sites Cells, Cultured Carrier Proteins Gene Silencing Fibroblasts RNA Interference Protein-Serine-Threonine Kinases Recombinant Fusion Proteins RNA, Small Interfering E2F1 Transcription Factor Gene Expression Regulation Suppressor of Cytokine Signaling Proteins Reverse Transcriptase Polymerase Chain Reaction Ubiquitination Cell Nucleus Oncogene Proteins, Viral Suppression, Genetic Gene Deletion Transcription Factor DP1 DNA Methylation Loss of Heterozygosity Kidney Neoplasms Papillomavirus E7 Proteins Ubiquitins Trans-Activators WT1 Proteins Models, Biological Tumor Burden Retinoblastoma-Binding Protein 1 Tumor Necrosis Factor-alpha DNA Primers Membrane Proteins Retinoblastoma-Like Protein p107 Immunohistochemistry Recombinant Proteins Hypoxia-Inducible Factor 1, alpha Subunit G1 Phase Breast Neoplasms Mice, Knockout Wilms Tumor Mice, Nude DNA, Neoplasm Cell Aging DNA

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