Alzheimer DiseaseGenotypeDisease SusceptibilityGenetic Predisposition to DiseaseAmyloid beta-PeptidesApolipoprotein E4Apolipoproteins EPolymorphism, Single NucleotideAllelesPolymorphism, Genetictau ProteinsAmyloid beta-Protein PrecursorGene FrequencyBrainNeurofibrillary TanglesHaplotypesGeneticsPlaque, AmyloidGenetic VariationCase-Control StudiesGenome-Wide Association StudyLinkage DisequilibriumApolipoprotein E3Genetic MarkersPhenotypeCognition DisordersAmyloid Precursor Protein SecretasesGenetic LinkageDementiaChromosome MappingGenetics, PopulationPresenilin-1MutationAge of OnsetAmyloidNeuropsychological TestsAtrophyMolecular Sequence DataDementia, VascularGenetic TestingModels, GeneticMice, TransgenicApolipoprotein E2Mild Cognitive ImpairmentNeurofibrilsDisease Models, AnimalPeptide FragmentsMicrobial Sensitivity TestsGenome, HumanEpistasis, GeneticAgingRisk FactorsGenetic Association StudiesPolymerase Chain ReactionHeterozygoteMice, Inbred C57BLPresenilin-2Cohort StudiesMagnetic Resonance ImagingSequence Analysis, DNAGenetic LociPedigreeHippocampusCognitionMental Status ScheduleDisease ProgressionHLA-DQ AntigensEuropean Continental Ancestry GroupHomozygoteQuantitative Trait LociAmino Acid SequencePlant DiseasesBase SequenceGenetic Diseases, InbornHLA-DRB1 ChainsLewy Body DiseaseNod2 Signaling Adaptor ProteinMicrosatellite RepeatsNeuronsCrohn DiseaseHLA-DQ beta-ChainsImmunity, InnateMice, KnockoutPresenilinsHLA-DR3 AntigenAniline CompoundsHLA-DR AntigensMemantineAspartic Acid EndopeptidasesComplement C4aAsian Continental Ancestry GroupBiological MarkersCholinesterase InhibitorsAnti-Bacterial AgentsLongitudinal StudiesCrosses, GeneticPolymorphism, Restriction Fragment LengthCerebral Amyloid AngiopathyMemory DisordersCerebral Cortex