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Gas Chromatography-Mass SpectrometryMass SpectrometryChromatography, GasChromatography, LiquidChromatography, High Pressure LiquidVolatile Organic CompoundsSolid Phase MicroextractionMetabolomicsTandem Mass SpectrometryMetabolomePerianal GlandsSpectrometry, Mass, Electrospray IonizationOils, VolatileVolatilizationOcimum basilicumChromatography, Thin LayerAndrostenediolsAcetic AnhydridesSubstance Abuse DetectionMeconiumDeuteriumDoping in SportsF2-IsoprostanesMagnetic Resonance SpectroscopyFatty AcidsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationBiotransformationCarboxylic AcidsHydroxyeicosatetraenoic AcidsGasesReproducibility of ResultsUrinalysisQuality ControlOxidation-ReductionEstersSteroidsMolecular StructureMethylationWater Pollutants, ChemicalSensitivity and SpecificityCarbohydrate ConformationCarbohydrate SequenceMolecular Sequence DataLipoxygenasePolycyclic Hydrocarbons, AromaticStereoisomerismChemistryChemical PhenomenaArachidonic AcidsArachidonic AcidHydrolysisProteomicsDinoprostCytochrome P-450 Enzyme SystemFatty Acids, UnsaturatedBiological MarkersLiverHexanesTime FactorsCalibrationChromatography, AffinityCattleChromatography, Ion ExchangeKineticsEucommiaceaeAmino Acid SequenceReference StandardsLimit of DetectionFlame IonizationIsotope LabelingLipid MetabolismChromatographyPentanes8,11,14-Eicosatrienoic AcidProteomeChromatography, GelRhodiolaBreath TestsReference ValuesChromatography, Reverse-PhaseWater PollutantsCarbon RadioisotopesSugar AcidsMethanolCarbon IsotopesEnvironmental MonitoringDose-Response Relationship, DrugGlucoseCholesterolOligosaccharidesAcetatesMicrosomes, LiverSugar AlcoholsOxidative StressSolid Phase ExtractionSulfur CompoundsPeptidesFungicides, IndustrialTerphenyl CompoundsPesticide Residues
HPLCSpectrometerDetectionFlameSolid-phase microextrNuclear MagneticSpectroscopyCapillaryTandemCompoundsAnalysisInstrumentationLiquidSpectrometersIonsWorkflowsChromatographsSolventOrganicOdorAcidSpeciesTime-of-FliGreenhouseSystemChemicalFasterMethodsIonizationColourlessTemperatureMethodSamplePerformanceApplicationsTechnologyFeatures
HPLC5
  • Established isotope ratio mass spectrometry methods for analyzing urinary steroids for doping control purposes consist of up to two time-consuming HPLC purification steps to achieve the required purity of all analytes. (uni-koeln.de)
  • Asynt has introduced GasTrap gas purifiers for analytical laboratories using Gas Chromatography (GC), High Performance Liquid Chromatography (HPLC) or Mass Spectrometry (GC/MS) instrumentation. (news-medical.net)
  • It is home to several advanced analytical instruments including high performance liquid (HPLC) and gas (GC) chromatographs with a variety of detectors, liquid chromatography with tandem mass spectrometry (LCMSMS), atomic absorption spectrophotometer (AAS), ion chromatograph (IC), nutrient autoanalyser, and total organic carbon analyser. (auckland.ac.nz)
  • Further preparative separation by high-pressure liquid chromatography (HPLC) of the wood fraction followed by GC-MS allowed retention and mass spectral characterisation of additional compounds originating from wood. (sun.ac.za)
  • The methanolic extract underwent high-performance liquid chromatography with a diode-array detector (HPLC-DAD) to determine the presence of phenolic compounds. (bvsalud.org)
Spectrometer13
  • SwRI's instrumentation for GLP 5-batch analysis includes a triple quadrupole (QQQ) mass spectrometer (TQMS) with an ultra-high performance liquid chromatography (UHPLC) separation module. (swri.org)
  • The GC-MS is composed of two major building blocks: the gas chromatograph and the mass spectrometer. (iitk.ac.in)
  • The molecules take different amounts of time (called the retention time) to come out of (elute from) the gas chromatograph, and this allows the mass spectrometer downstream to capture, ionize, accelerate, deflect, and detect the ionized molecules separately. (iitk.ac.in)
  • The mass spectrometer does this by breaking each molecule into ionized fragments and detecting these fragments using their mass to charge ratio. (iitk.ac.in)
  • The most common type of mass spectrometer (MS) associated with a gas chromatograph (GC) is the quadrupole mass spectrometer, sometimes referred to by the Hewlett-Packard (now Agilent) trade name "Mass Selective Detector" (MSD). (iitk.ac.in)
  • Another relatively common detector is the ion trap mass spectrometer. (iitk.ac.in)
  • Detection was performed simultaneously by isotope ratio mass spectrometry and a single quadrupole mass spectrometer for analyte identity confirmation and assessment of peak purity. (uni-koeln.de)
  • Analysis is performed using an HP 5890 Series II Plus GC (Gas Chromatograph) with an HP 5972 MSD (Mass Selective Detector Quadrupole Mass Spectrometer) and EnviroQuant software. (cdc.gov)
  • Atoms and molecules must first be ionized before they can be accelerated through the mass spectrometer and detected. (thermofisher.com)
  • The heart of the mass spectrometer is its mass analyzer. (thermofisher.com)
  • Samples must be ionized (or charged) before they can be manipulated by electric and magnetic fields within the mass spectrometer. (thermofisher.com)
  • The possibility of using semiconductor sensors as a replacement for the mass spectrometer or ion mobility spectrometer in gas chromatography is also being researched in order to be able to provide a cost-effective analysis tool for at-line analysis. (ifnano.de)
  • The experiments involved in this study included determining TD-GC-MS parameters suitable for efficient analyte separation and quantitation on the HAPSITE ER, determinations of analyte mass loadings that cause mass spectrometer detector saturations, generation of calibration curves, estimations of the limits of detection (LODs) and quantification (LOQs), as well as desorption efficiency and relative response factor repeatability. (cdc.gov)
Detection8
  • It has a three way splitter which enables the simultaneous detection by three detectors for analysis, i.e Micro ECD, NPD with EPC and MS. (iitk.ac.in)
  • The purpose of TTBB is to function as an analogue of pentafluorobenzyl bromide (PFBB) in electrophoric derivatization reactions prior to detection by gas chromatography-electron-capture negative ion mass spectrometry (GC-ECNI-MS). In more detail, it was anticipated that TTBB could be used along with, or as a substitute for, PFBB to help control some interferences and confirm results. (cdc.gov)
  • The readily reproducible methods range from gas and liquid chromatography coupled to mass spectrometry detection and other classic detectors, to capillary electrophoresis and immunochemical or radioimmunoassay methods. (nhbs.com)
  • The aroma profiles of hops were detected by flavor-detection methods including Gas chromatogram-flame ionization detector (GC-FID), Gas chromatography-mass spectrometry (GC-MS), Headspace solid-phase microextraction/gas chromatogram-mass spectrometry (HS-SPME/GC-MS), and sensory evaluation. (unl.edu)
  • A wide variety of standard-value, reference solutions designed to facilitate accurate chromatography-based detection protocols for pesticides. (fishersci.com)
  • The method has been modified to use 3M 3520 Organic Vapor Monitors (OVM) (manufactured without glued-on labels) as the sampling media and gas chromatography/mass spectrometry (GC/MS) as the detection device (2). (cdc.gov)
  • Headspace gas chromatography with flame ionization detection (GC-FID) is often used for residual solvent testing of pharmaceuticals, though the qualitative power of this method is not particularly high. (shimadzu.com)
  • Mass spectrometry has four essential functions, which are ionization, separation (filtering), detection and analysis. (thermofisher.com)
Flame6
  • Retention time stability and transfer windows were monitored by a flame ionization detector. (uni-koeln.de)
  • Changing levels with ageing were quantified for the most abundant compounds by direct split injection of whiskeys on a gas chromatograph equipped with a flame ionisation detector. (sun.ac.za)
  • The emissions of 102 VOCs, including isoprene, α -pinene, β -pinene, and other VOC species, were analyzed with a custom-built online gas chromatography-mass spectrometry/flame ionization detector system. (copernicus.org)
  • flame ionization detector (GC-FID) / Nurlaila Ismail … [et al. (uitm.edu.my)
  • Characterization of agarwood incense using gas chromatography - mass spectrometry (GC-MS) coupled with solid phase micro extraction (SPME) and gas chromatography - flame ionization detector (GC-FID) / Nurlaila Ismail … [et al. (uitm.edu.my)
  • This paper presents the application of Solid Phase Micro Extraction (SPME) coupled with Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography-Flame Ionization Detector (GC-FID) to characterize agarwood incense. (uitm.edu.my)
Solid-phase microextr1
  • The authors have focused on extraction and cleanup procedures, in order to develop and optimize more fully automated and miniaturized methods, including solid-phase extraction, solid-phase microextraction, microwave-assisted extraction, and on-line tandem liquid chromatography (LC/LC) trace enrichment, among others. (nhbs.com)
Nuclear Magnetic1
  • Dr. Samburova's research group focuses on the analysis of these atmospheric organic species with different analytical techniques, including gas chromatography (GC) mass spectrometry (MS), liquid chromatography with UV-Vis and MS detectors, nuclear magnetic resonance (H-NMR), and UV-Vis spectrophotometry. (dri.edu)
Spectroscopy2
  • The precise molecular geometry of gaseous formaldehyde has been determined by gas electron diffraction and microwave spectroscopy. (wikipedia.org)
  • In This Edition Chromatography Articles - Faster and automated analysis of aroma compounds in cosmetics Mass Spectrometry & Spectroscopy Articles - Frequently Asked Questions (FAQ) abou. (labmate-online.com)
Capillary2
  • The gas chromatograph utilizes a capillary column which depends on the column's dimensions (length, diameter, film thickness) as well as the phase properties (e.g. 5% phenyl polysiloxane). (iitk.ac.in)
  • The volatile compounds isolated from whiskey by fractional vacuum distillation were identified by two-dimensional capillary gas chromatography/mass spectrometry. (sun.ac.za)
Tandem2
  • Mass spectrometry is an analysis method that can be performed once using a single analyzer, or it can be performed in tandem between different mass analyzers (such as those found in hybrid or tribrid mass spectrometers). (thermofisher.com)
  • The practice of simultaneous MS is frequently termed tandem mass spectrometry (MS/MS or MS 2 ) and refers to two or more reaction steps being performed on selected ions. (thermofisher.com)
Compounds6
  • The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. (wordtrade.com)
  • The low-volatility wood-originating compounds isolated from whiskey by vacuum fractional distillation were analysed by high-resolution gas chromatography and mass spectrometry (GC-MS). Three phenolic esters previously unreported in whiskey were identified and confirmed by synthesis. (sun.ac.za)
  • The essential oil was obtained by hydro-distillation, and its volatile components were analyzed by gas chromatography-mass spectrometry (GC-MS). The results revealed the presence of various aromatic and terpene compounds, with carvacrol being the most abundant compound. (bvsalud.org)
  • GC/MS analysis allows separation of compounds based on their retention time within a chromatography column and identification of each compound by the characteristic fragments into which a given chemical is broken following ionization of the compound. (medscape.com)
  • Over the years, technologic advances in electronics and detectors have allowed GC/MS to detect ever smaller concentrations of compounds, as has the addition of other analytical techniques, such as liquid chromatography. (medscape.com)
  • The new ultra-high performance super- critical fluid chromatography method was also applied for the qualitative and quantitative analysis of lignin-derived phenolic compounds obtained upon alkaline cupric oxide oxida- tion of a commercial humic acid. (lu.se)
Analysis11
  • Since cyanide forms volatile hydrogen cyanide gas, tissue sampling techniques, storage, and cyanide analysis must be done with caution. (cdc.gov)
  • This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. (wordtrade.com)
  • Which type of chromatography is best for cannabis analysis? (news-medical.net)
  • Because gas chromatography mass spectrometry (GC/MS) utilizes MS to perform qualitative analysis based on mass spectra, GC/MS can be used to estimate and identify individual peaks detected in the expected vicinity of a target solvent as well as other unknown peaks. (shimadzu.com)
  • All analyses were conducted on a Gas Chromatography-Mass Spectrometry (GC-MS)-Olfactometry system where the human nose is used as a detector simultaneously with chemical analysis via MS. The effects of sampling time, distance from a source, and the presence of particulate matter (PM) on the abundance of specific gases, odor intensity, and odor character were tested. (iastate.edu)
  • In the first step of mass analysis, precursor ions are formed in the ion source and induced to fragment. (thermofisher.com)
  • The different approaches to sample labeling and mass spectrometry analysis. (thermofisher.com)
  • The quantitative results in the pesticide residue analysis by gas chromatography-mass spectrometry are adversely affected by the phenomenon known as the matrix effects. (analchemres.org)
  • Samples were extracted by dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry analysis. (analchemres.org)
  • Evaluation of the Matrix Effects in Herbal-Based Potions in Pesticide Residues Analysis by Dispersive Liquid-Liquid Microextraction Followed by Gas Chromatography-Mass Spectrometry', Analytical and Bioanalytical Chemistry Research , 9(3), pp. 269-280. (analchemres.org)
  • The high separation power and short analysis time obtained demonstrate for the first time that supercritical fluid chromatography is a fast and reliable technique for the analysis of lignin-derived phenols in complex environmental samples. (lu.se)
Instrumentation1
  • The purpose of this work was to develop a reliable analytical method for rapid and on-site assessments of occupational VOC exposures using field-capable thermal desorption-gas chromatography-mass spectrometry (TD-GC-MS) instrumentation (i.e. the HAPSITE ER). (cdc.gov)
Liquid6
  • Gas chromatography-mass spectrometry (GC-MS) is a method that combines the features of gas-liquid chromatography and mass spectrometry to identify different substances within a test sample. (iitk.ac.in)
  • The result of biodegradation by the bacteria was determined by undertaking high-performance liquid chromatography of the metabolites produced. (intechopen.com)
  • Pharmaceutical, food and industrial laboratories can optimize their routine testing and quality control (QC) workflows with an enhanced high-performance liquid chromatography system that delivers maximized instrument uptime and precision for any operator, regardless of experience. (news-medical.net)
  • What's the difference between High Performance Liquid Chromatography and Ion Chromatography? (news-medical.net)
  • These inclusions preserve for us tiny samples of the liquid and/or the gas phase that was present during formation, although in some cases they may have undergone significant changes from the original material. (usgs.gov)
  • When combined with chromatography, such as liquid or gas chromatography, the potential for MS to identify and quantitate analytes of interest increases dramatically. (thermofisher.com)
Spectrometers3
  • This is because mass spectrometers separate particles by calculating their different mass-to-charge ratios (m/z). (thermofisher.com)
  • Different analyzers are also combined in hybrid and tribrid mass spectrometers. (thermofisher.com)
  • The general operation of mass spectrometers, including hybrid and tribrid mass spectrometers. (thermofisher.com)
Ions1
  • Learn more about how mass analyzers separate, select and even fragment ions based on their distinct masses and charges. (thermofisher.com)
Workflows1
Chromatographs1
  • Multidimensional gas chromatography consists of two gas chromatographs connected by a pressure-controlled heart-cutting device. (uni-koeln.de)
Solvent2
  • We describe an example of residual solvent test of a pharmaceutical using a detector splitting system that simultaneously obtains FID and MS data in a single measurement. (shimadzu.com)
  • A matrix effect may be noticed as an increase or decrease in the response of the detector signal compared with the response produced by solvent solutions of the analytes. (analchemres.org)
Organic3
  • Gas chromatography is performed on fuels and related products for organic speciation. (canada.ca)
  • We used a sample crusher and a gas chromatography-mass spectrometry (GC-MS) system to analyze for organic and inorganic volatiles present as major to trace constituents in inclusions. (usgs.gov)
  • A NIOSH-certified CBRN PAPR with a loose-fitting face-piece, hood, or helmet and a filter or a combination organic vapor, acid gas, and particulate cartridge/filter combination or a continuous flow respirator for air levels greater than AEGL-1. (cdc.gov)
Odor3
  • A colorless gas with a characteristic pungent, irritating odor. (wikipedia.org)
  • This is because odor-causing gases are often present at very low concentrations in a complex matrix of less important or irrelevant gases. (iastate.edu)
  • The abundance of specific gases and odor was amplified when plates collected PM. The results of this research indicate that PM is major carrier of odor and several key swine odorants. (iastate.edu)
Acid1
Species6
  • The molecular diffusivities of larger PAHs and soot particles approach zero leading to differential diffusion with gas-phase species. (imperial.ac.uk)
  • The present work systematically quantifies the impact on soot moments, soot related statistical correlations and Particle Size Distributions (PSDs) using a fully coupled transported joint probability density function (JPDF) method featuring a 78-dimensional joint-scalar space, including enthalpy, gas phase species with the PSD discretised using 62 size classes via a mass and number density preserving sectional method. (imperial.ac.uk)
  • Similar observations are made for correlations between the soot volume fraction and the mass fractions of gas-phase species such as CO, OH, H and C2H2. (imperial.ac.uk)
  • A mass and number density preserving sectional model is here combined with a transported joint-scalar probability density function (JDPF) method that enables a fully coupled scalar space of soot, gas-phase species and enthalpy. (imperial.ac.uk)
  • The importance of differential diffusion between soot and gas-phase species intensifies with pressure with the impact on PSDs more evident for larger particles which tend to be transported towards the fuel rich centreline leading to reduced soot oxidation. (imperial.ac.uk)
  • Ruminants, comprising the majority of ungulate species, must regularly eruct gases from the foregut to relieve excess pressure and maintain a chemical equilibrium. (biologists.com)
Time-of-Fli1
  • Some examples of mass analyzers include quadrupoles , triple quadrupoles , ion traps , Orbitraps, Fourier transform, magnetic sectors and time-of-flight (TOF) instruments. (thermofisher.com)
Greenhouse1
  • Besides its medicinal uses, Moringa oleifera biodiesel has shown remarkable potentiality in conducing to the decrease of greenhouse gases and guaranteeing sustainable supply of energy. (academicjournals.org)
System1
  • In order to be able to connect the sensors directly to the system control, electrical noses based on semiconductor detectors are also being developed. (ifnano.de)
Chemical1
  • She explained that the compound of interest, ethylene oxide, is a colourless, odourless gas that is used to sterilise medical devices and has been implicated as a cancer-causing chemical. (hamamedia.com)
Faster1
  • It found that colon and rectum resection patients who chewed gum along with their post-surgery treatment plan were hungrier sooner, and passed gas and their first bowel movement significantly faster than those not chewing gum. (healthnews.com)
Methods2
  • The Institute for Nanophotonics in Göttingen develops analytical at-line methods for volatile aromas based on gas chromatography-mass spectrometry and gas chromatography-ion spectrometry coupling. (ifnano.de)
  • Alkaline cupric oxide (CuO) oxidation is one of the mostly performance supercritical fluid chromatography (UHPSFC) adopted methods for analyzing lignin in various complex using columns with sub-2 m packing can further improve environmental matrices such as soils and sediments [9]. (lu.se)
Ionization1
  • Samples ranging from 1 mg to 1 g were crushed and the released volatiles were analyzed using multi-chromatographic columns and detectors, including the sensitive helium ionization detector. (usgs.gov)
Colourless1
  • The compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde (refer to section Forms below). (wikipedia.org)
Temperature1
Method1
  • Mass Spectrometry Basics by Christopher G. Herbert, R. A. W. Johnstone (CRC Press) Provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. (wordtrade.com)
Sample1
Performance1
  • UHPSFC , ultra- pacted by other parameters, such as the addition of the mod- high performance supercritical fluid chromatography ifier and the change of the mobile phase density [20]. (lu.se)
Applications1
  • Mass Spectrometry Basics describes processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. (wordtrade.com)
Technology2
  • Serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology. (wordtrade.com)
  • Learn how Orbitrap technology has revolutionized mass spectrometry for over a decade. (thermofisher.com)
Features1
  • At Analytica 2016, the trade show for the laboratory field taking place in Munich from May 10th to 13th, KNAUER will be introducing a newly developed refractive index (RI) detector with most up-to-date features. (news-medical.net)