• The in-house adenovirus assay is a sensitive and reliable assay with lower cost for the detection and quantification of adenoviral DNA when compared to the RealStar® Adenovirus PCR Kit. (biomedcentral.com)
  • Twenty-one cases were infected with two viruses, with the most frequent mixture being adenovirus and influenza A virus (n = 5). (datexis.com)
  • Adenovirus was present in 62.5% (n = 15) of mixed infections which was almost a half (46.9%) of all detections for this virus. (datexis.com)
  • Additionally, we obtained the complete or near-complete genome of bovine rhinitis B, enterovirus E1, bovine viral diarrhea virus (sub-genotypes 1a and 1c) and bovine respiratory syncytial virus, and partial sequences of other viruses. (biomedcentral.com)
  • Human parainfluenza virus (HPIV) contributes to acute respiratory tract infection burden in young children ( 1 ) and adults ( 2 ). (cdc.gov)
  • Human PIVs (HPIVs) are currently divided into 5 serotypes-HPIV-1, HPIV-2, HPIV-3, HPIV-4a, and HPIV-4b-in 2 different genera: Respirovirus (HPIV-1 and HPIV-3) and Rubulavirus (HPIV-2 and HPIV-4). (medscape.com)
  • HPIV is closely related to Hendra virus, Nipah virus, and metapneumoviruses. (medscape.com)
  • HPIV-1 is most commonly associated with croup. (medscape.com)
  • HPIV-3 is second only to respiratory syncytial virus (RSV) as a cause of pneumonia and bronchiolitis in infants and young children. (medscape.com)
  • The seasonal patterns of HPIV-1, HPIV-2, and HPIV-3 are curiously interactive. (medscape.com)
  • HPIV-1 causes the largest, most defined outbreaks, which are marked by sharp biennial rises in croup cases in the autumn of odd-numbered years. (medscape.com)
  • Outbreaks of infection with HPIV-2, although erratic, usually follow HPIV-1 outbreaks. (medscape.com)
  • Outbreaks of HPIV-3 infections occur yearly, mainly in spring and summer, and last longer than outbreaks of HPIV-1 and HPIV-2. (medscape.com)
  • Asymptomatic infection can be induced in hamsters, guinea pigs, and adult ferrets by all 5 serotypes of HPIV (HPIV-1, HPIV-2, HPIV-3, HPIV-4a, and HPIV-4b). (medscape.com)
  • Chimpanzees, macaques, squirrels, owls, and rhesus monkeys have been asymptomatically infected with HPIV-3 or HPIV-4, and only marmosets have developed symptomatic upper respiratory tract infections (URTIs) with HPIV-3 and Sendai virus. (medscape.com)
  • BackgroundHuman parainfluenza virus (hPIV) is a common virus in childhood acute lower respiratory infections (ALRI). (ox.ac.uk)
  • Adjustment was made to account for the non-detection of hPIV-4. (ox.ac.uk)
  • Coronavirus disease 2019 (COVID-19) is an acute infection of the respiratory tract that emerged in late 2019 1 , 2 . (nature.com)
  • A novel coronavirus, SARS-CoV-2, was recently identified causing pneumonia in humans, termed coronavirus disease 2019 (COVID-19). (peerj.com)
  • One-tube singleplex assay for the detection of the human coronavirus SARS-CoV-2 and internal control. (siemens-healthineers.com)
  • In this Respiratory Virus Report, the number of detections of coronavirus reflects only seasonal human coronaviruses, not the novel pandemic coronavirus (SARS-CoV-2) that causes COVID-19. (canada.ca)
  • In this review, we provide an overview of the literature on respiratory infections at mass gatherings, then describe the impact of novel coronavirus 2012 (nCoV), an emerging respiratory disease virus, on the preparations for mass gathering. (who.int)
  • Dans la présente revue, nous proposons un aperçu de la littérature sur les infections respiratoires lors de rassemblements de masse, puis nous décrivons l'impact du nouveau coronavirus 2012, un virus respiratoire émergent, sur les préparatifs des rassemblements de masse. (who.int)
  • Toutefois, le nouveau coronavirus a sévi avant la saison du pèlerinage du Hadj de 2012 et les musulmans ont accompli leurs obligations religieuses sans contracter d'infection par ce virus. (who.int)
  • 1 In that study picornaviruses (mostly rhinoviruses) accounted for two thirds of the viral infections, with coronavirus causing less severe asthma exacerbations than other respiratory viruses. (bmj.com)
  • Before the outbreak of severe acute respiratory syndrome caused by the SARS coronavirus in 2003, human coronaviruses (HCoVs) had not been considered harmful respiratory pathogens. (hindawi.com)
  • Bosphore SARS-CoV-2/Flu/RSV Panel Kit detects and discriminates 2019-nCoV (which is later renamed officially as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by WHO), RSV A&B and influenza A&B in human respiratory samples including nasopharyngeal, oropharyngeal swabs and saliva. (anatoliageneworks.com)
  • Reporting bias on the part of participating global travel, mask use, physical distancing, and staying home) laboratories was minimized by requiring the following pathogen- reduced transmission of some viral respiratory pathogens ( 1 ). (cdc.gov)
  • We compared self- and staff-collected swabs in terms of swabbing quality and detection of viral respiratory pathogens. (plos.org)
  • Nasal self-swabbing for identification of viral ARI pathogens proved to be equivalent to staff-swabbing in this population in terms of acceptance and pathogen detection. (plos.org)
  • Akmatov MK, Gatzemeier A, Schughart K, Pessler F (2012) Equivalence of Self- and Staff-Collected Nasal Swabs for the Detection of Viral Respiratory Pathogens. (plos.org)
  • The self-collected swabs had a sensitivity of 86% for the detection of respiratory pathogens compared to the gold standard [4] . (plos.org)
  • found similar detection rates for respiratory pathogens between self- and staff-collected midturbinate swabs when one staff-collected and one self-collected swab were taken from opposite nostrils during the same visit to a campus health center [5] . (plos.org)
  • Reliable and timely diagnosis of respiratory pathogens can help differentiate among viruses, improve clinical decision making, and prevent viral outbreaks. (roche.com)
  • This test has been authorized only for the detection of nucleic acid from SARS-CoV-2, not for any other viruses or pathogens. (siemens-healthineers.com)
  • While FilmArray performs PCR to initially amplify nucleic acids from target pathogens, its multiplexed detection capabilities are primarily enabled by high-resolution melt curve analysis, a method that can "qualitatively pick up PCR products for diagnostic purposes that qPCR can't," Idaho Tech co-founder Carl Wittwer said at a scientific conference last week. (genomeweb.com)
  • The FTD™ Respiratory pathogens 21 assay 1 is a qualitative in vitro nucleic acid amplification test for the detection and differentiation of specific viral and bacterial nucleic acids in nasopharyngeal swab specimens of human origin. (siemens-healthineers.com)
  • Provides simultaneous detection of probable pathogens with one kit using a single sample for increased testing efficiency. (siemens-healthineers.com)
  • However, the detection of viral pathogens does not always indicate active disease. (medscape.com)
  • Similarly, respiratory syncytial virus (RSV) and cytomegalovirus (CMV) can be detected in the presence of other known bacterial pathogens. (medscape.com)
  • Respiratory viruses (RVs) are pathogens that can cause central nervous system (CNS) infection, but previous research has been limited to a pediatric population. (encephalitisjournal.org)
  • While some viruses and bacteria have been widely studied and are known to be an important component of the respiratory complex, novel, emerging or unrecognised pathogens are not easily detected because they are not routinely considered in the differential diagnosis or laboratory diagnostic assays are not available. (biomedcentral.com)
  • Metagenomics approaches have facilitated the detection of complete microbiomes and viromes, including emerging pathogens or pathogens that cannot be easily cultured and isolated. (biomedcentral.com)
  • Influenza refers to illness caused by the influenza viruses, but the term is commonly and incorrectly used to refer to similar illnesses caused by other viral respiratory pathogens. (msdmanuals.com)
  • There are 18 H types and 11 NA types, giving 198 possible combinations, but only a few are human pathogens. (msdmanuals.com)
  • The human coronaviruses (HCoVs) HCoV-NL63 and HCoV-HKU1 are two recently discovered coronaviruses that circulate widely and are associated with acute respiratory infections (ARI). (hindawi.com)
  • The outbreak of SARS renewed interest in this virus family and resulted in the identification of two additional HCoVs, HCoV-NL63 and HCoV-HKU1. (hindawi.com)
  • HCoV-HKU1, a group II virus, was detected in an adult with chronic pulmonary disease in Hong Kong in 2005 [ 2 ]. (hindawi.com)
  • In this study, we screened for the presence of HCoV-NL63 and HCoV-HKU1 in children with acute respiratory infection admitted to the Beijing Children's Hospital in an effort to gain a better understanding of the seasonality, epidemiology and genetic diversity of these viruses in a city with a population of more than 22 million. (hindawi.com)
  • Sendai virus is used as a backbone for vaccine development against Mycobacterium tuberculosis that causes tuberculosis, against HIV-1 that causes AIDS and against other viruses, including those that cause severe respiratory infections in children. (wikipedia.org)
  • Epizootic infections of mice are usually associated with a high mortality rate, while enzootic disease patterns suggest that the virus is latent and can be cleared over the course of a year. (wikipedia.org)
  • The virus is immunosuppressive and may predispose to secondary bacterial infections. (wikipedia.org)
  • Clinical diagnostic tests based on nucleic acid amplification assist with the prompt diagnosis of microbial infections because of their speeds and extremely low limits of detection. (ox.ac.uk)
  • However, antibody production in children less than 2 years may be delayed until they have sustained recurrent parainfluenza infections. (virology-online.com)
  • Parainfluenza viruses are found uncommonly associated with other respiratory tract infections in children such as tracheobronchitis, bronchiolitis, and bronchopneumonia. (virology-online.com)
  • Parainfluenza viruses produce disease throughout the year, but peak prevalence rates occur during wintertime outbreaks of respiratory tract infections, especially croup, in children throughout the temperate zones of the northern and southern hemispheres. (virology-online.com)
  • Most infections are endemic, but sharp small epidemics occasionally occur with types 1 and 2. (virology-online.com)
  • Parainfluenza virus infections are primarily childhood diseases, the highest age-specific attack rates for croup occur in children below the age of 3 years. (virology-online.com)
  • Type 4 viruses induce few clinical illnesses but infections are common, 70 - 80% of children have antibodies by 10 years of age. (virology-online.com)
  • Even in children, the majority of infections with parainfluenza viruses are subclinical. (virology-online.com)
  • The virus infections spread readily within the team, most commonly within the same sport discipline. (bmj.com)
  • Streptococcus pyogenes is a major human-specific bacterial pathogen that causes a wide array of manifestations ranging from mild localized infections to life-threatening invasive infections. (nih.gov)
  • [1] Ineffective treatment of S. pyogenes infections can result in the postinfectious sequela acute rheumatic fever and post-streptococcal glomerulonephritis. (nih.gov)
  • There have been reports of human infections by some of the other nonhuman PIVs, but these have not been well established. (medscape.com)
  • Double or triple infections with HRV-C and respiratory syncytial virus and/or bocavirus were diagnosed in 33.3% of the HRV-infected patients, but no correlation with severity of clinical outcome was observed. (plos.org)
  • Human adenoviruses are common causes of community-acquired respiratory tract and enteric infections. (biomedcentral.com)
  • Influenza C virus is detected considerably less usually and typically results in moderate infections, hence does not present public overall health relevance. (infotrace.net)
  • RVs mainly cause upper or lower respiratory tract infections, but they can also cause central nervous system (CNS) infection, mostly in children [ 1 ]. (encephalitisjournal.org)
  • [ 1 ] Pediatric bacterial brain abscesses, epidural empyemas, and subdural empyemas, rare complications of respiratory infections and sinusitis, are often caused by Streptococcus species but might also be polymicrobial or caused by other genera, such as Staphylococcus . (medscape.com)
  • It is now recognized that both these viruses have a worldwide circulation and are associated with human respiratory tract infections. (hindawi.com)
  • Respiratory Tract Viral Infections and Coinfections Identified by Anyplex™ II RV16 Detection Kit in Pediatric Patients at a Riyadh Tertiary Care Hospital - 2.3. (datexis.com)
  • Of the 172 that tested positive for respiratory agents, there were 24 (14.0%) cases with mixed infections of two or three viruses. (datexis.com)
  • Over the last decade, improvements in surgical techniques, lung preservation, immunosuppression, and management of ischaemia/reperfusion injury and infections have contributed to increase the 1‐yr patient survival after lung transplantation (LTx) to 70-80% 1 . (ersjournals.com)
  • 1.HIV infections - diagnosis. (bvsalud.org)
  • Although respiratory infections can be classified by the causative virus (eg, influenza), they are generally classified. (msdmanuals.com)
  • The virus is responsible for a highly transmissible respiratory tract infection in mice, hamsters, guinea pigs, rats, and occasionally marmosets, with infection passing through both air and direct contact routes. (wikipedia.org)
  • Inbred and outbred mouse and rat strains have very different susceptibility to Sendai virus infection. (wikipedia.org)
  • It was shown that resistance to the lethal effects of Sendai virus in mice is genetically controlled and expressed through control of viral replication within the first 72 hours of infection. (wikipedia.org)
  • Human Parainfluenza Virus Infection in Severe Acute Respiratory Infection Cases in Beijing, 2014-2016: a Molecular Epidemiological Study. (cdc.gov)
  • Development of LAMP assays for the molecular detection of taeniid infection in canine in Tibetan rural area. (cdc.gov)
  • The spectrum of infection with SARS-CoV-2 virus is quite wide ranging from asymptomatic infection to symptomatic illness. (cdc.gov)
  • HAI antibodies appear in the sera 1 - 2 weeks after infection and persist for several years. (virology-online.com)
  • Croup, or laryngotracheobronchitis is the commonest clinical manifestation of parainfluenza virus infection. (virology-online.com)
  • Occasionally, a mild non-specific illness is seen after parainfluenza virus infection. (virology-online.com)
  • In adults, parainfluenza virus infection may be asymptomatic or result in a mild 'cold' or URTI. (virology-online.com)
  • Although parainfluenza 3 may produce croup, more typically, it produces a spectrum of infection that closely mimics that produced by RSV, including bronchiolitis and pneumonia. (virology-online.com)
  • Main outcome measure Clinical respiratory illness (CRI), influenza-like illness (ILI) and laboratory-confirmed respiratory virus infection. (bmj.com)
  • Respiratory epithelium appears to be the major site of virus binding and subsequent infection. (medscape.com)
  • Global burden of acute lower respiratory infection associated with human parainfluenza virus in children younger than 5 years for 2018: a systematic review and meta-analysis. (ox.ac.uk)
  • Human rhinoviruses (HRVs) are a highly prevalent cause of acute respiratory infection in children. (plos.org)
  • Gesiotto Q, Cheema A, Avaiya K, Shah B, Greene J. COVID-19 Virus Infection in Three Patients With Hypogammaglobulinemia. (moffitt.org)
  • Symptoms start off 1-4 times just after infection and commonly past around a week. (infotrace.net)
  • Seasonal influenza (the flu) is an acute respiratory an infection caused by influenza viruses. (infotrace.net)
  • Wellness and care employees are at substantial possibility of buying influenza virus an infection thanks to increased exposure to the clients, and of even further spreading especially to susceptible men and women. (infotrace.net)
  • To diagnose these viruses, screening test of RV PCR is recommended even in patients without upper respiratory infection symptoms. (encephalitisjournal.org)
  • 1) clinical suspicion of CNS infection, (2) ≥18 years of age, and (3) cerebrospinal fluid (CSF) pleocytosis. (encephalitisjournal.org)
  • Neopterin in diagnosis of human immunodeficiency virus infection in infants. (ucsf.edu)
  • Respiratory syncytial virus B was the only aetiology that was not detected in a mixed infection. (datexis.com)
  • Mucosal IgA acts as a first line of defense and neutralizes viruses efficiently at the portal of entry, preventing infection of epithelial cells and generalization of infection. (crie.ru)
  • Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infection in infants and children and the second most common viral cause of pneumonia in adults. (medscape.com)
  • Influenza pneumonia: Amantadine hydrochloride and rimantadine hydrochloride are approved for the prevention and treatment of influenza A virus infection. (medscape.com)
  • Influenza C virus infection does not cause typical influenza illness and is not discussed here. (msdmanuals.com)
  • HCoV-NL63, a member of the group I coronaviruses, was first detected in a child with bronchiolitis in The Netherlands in 2004 [ 1 ]. (hindawi.com)
  • The cobas ® Paraflu 1-4 UC Test for use with the cobas omni Utility Channel on the cobas ® 6800/8800 Systems is a high-throughput multiplex assay for the qualitative detection and differentiation of respiratory viruses parainfluenza 1, parainfluenza 2, parainfluenza 3, and parainfluenza 4. (roche.com)
  • Rapid Detection and Differentiation of Clinically Relevant Candida Species Simultaneously from Blood Culture Using A Novel Signal Amplification Approach. (cdc.gov)
  • The UW Clinical Virology Laboratory in the Department of Laboratory Medicine and Pathology incorporates the modified FDA approved Panther Fusion® assay for the detection and differentiation of Human parainfluenza viruses type 1, type 2 , type 3 and type 4 using real-time PCR. (uw.edu)
  • To assess the performance of automated molecular diagnostics system, GENECUBE Mycoplasma, in the detection of macrolide resistance mutations.Methodology related. (lynxgen.com)
  • 1 HPIVs often produce mild cold-like symptoms but can progress to severe clinical manifestations such as otitis media, pharyngitis, conjunctivitis, croup, tracheobronchitis, and pneumonia, which can result in life-threatening consequences. (roche.com)
  • Parainfluenza 1 and 2 are particularly prone to produce croup whilst parainfluenza 3 is prone to produce bronchiolitis and pneumonia. (virology-online.com)
  • The influenza viruses are the most common viral cause of pneumonia. (medscape.com)
  • Parainfluenza virus (PIV) is second in importance only to RSV as a cause of lower respiratory tract disease in children and pneumonia and bronchiolitis in infants younger than 6 months. (medscape.com)
  • Viruses account for the largest proportion of childhood pneumonia. (medscape.com)
  • One swab was analysed within 45 min using a molecular POCT for respiratory syncytial virus and influenza A and B viruses. (bmj.com)
  • There are 4 types of influenza viruses, styles A, B, C and D. Influenza A and B viruses circulate and induce seasonal epidemics of ailment. (infotrace.net)
  • Mucosal vector vaccines against human respiratory syncytial virus and human immunodeficiency virus type 1 based on Sendai virus, which is able to replicate asymptomatically in cells of bronchial epithelium, are also being investigated. (crie.ru)
  • Some influenza clinical laboratory data and all other respiratory virus data are decreased in early 2020 and did not increase until spring 2021. (cdc.gov)
  • Detection of loop-mediated isothermal amplification (LAMP) end product by color changes. (ajtmh.org)
  • cobas ® Paraflu 1-4 UC is an in vitro nucleic acid amplification test for the qualitative detection and discrimination of human Parainfluenza virus serotypes 1, 2, 3, and 4 (HPIV1-4). (roche.com)
  • 1 Influenza in children who attend school or childcare is central to the community spread of influenza and epidemic amplification. (who.int)
  • RT-Bst and RT-Bst PCR can be used as alternative approaches to reverse transcription and one-step RT-PCR, respectively, for sequence-independent amplification of RNA virus sequences and a larger scale analysis of this new diagnostic approach is warranted. (westminster.ac.uk)
  • Loop-mediated isothermal amplification (LAMP) assay has emerged as a novel alternative isothermal amplification method for the detection of nucleic acid. (peerj.com)
  • In order to further reduce costs and enable detection by the naked eye, we used hydroxynaphthol blue (HNB) dye for the colorimetric detection of the amplification reaction. (peerj.com)
  • We describe a reaction-specific RNA internal control for diagnostic reverse transcription (RT)-PCR which allows extraction, RT, amplification, and detection to be monitored. (ox.ac.uk)
  • The FilmArray instrument integrates sample preparation, amplification, detection, and analysis, and is designed to provide results in about an hour with about two minutes of hands-on time, according to the company. (genomeweb.com)
  • This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Act, 21. (siemens-healthineers.com)
  • In some immunocompromised patients, who shed the virus for long periods, the diagnosis can be of little clinical significance. (medscape.com)
  • In CDC's national call for cases, a case was defined as the diagnosis of brain abscess, epidural empyema, or subdural empyema in a person aged ≤18 years without a previous neurosurgical procedure or history of head trauma, hospitalized on or after June 1, 2021, irrespective of etiology. (medscape.com)
  • DuPont Qualicon science-based systems for pathogen detection and microbial monitoring, together with Danisco Care4U™ range of natural food protection solutions, help companies protect their products, productivity and brands. (rapidmicromethods.com)
  • Along with our esteemed distribution partners, we are pleased to offer our user-friendly multiplex pathogen detection system to the broad community of clinical laboratory professionals. (rapidmicromethods.com)
  • An EIA for the detection of antibodies to human hepatitis C virus in human serum or plasma. (launchdiagnostics.com)
  • As a result of vaccination against HPIV1 a significant boost in virus-specific neutralizing antibodies was observed. (wikipedia.org)
  • Conclusions: Children who received 2 doses of SARS-CoV-2 vaccine have a lower incidence of COVID-19 and higher levels of SARS-CoV-2 antibodies compared with who received 1 dose. (bvsalud.org)
  • Antibodies against types 1 and 2 are acquired less rapidly but 80% of children have antibodies against types 1 and 2 by 10 years of age. (virology-online.com)
  • Virus-neutralizing antibodies (activity decreased by 20.4% between the 1st and 6-8th mos but remained relatively stable thereafter and could be detected up to 12 months PSO. (ncipd.org)
  • The presence of SARS-CoV-2 specific IgG antibodies (seropositivity) in certain populations provides better understanding of virus circulation and transmission. (ncipd.org)
  • Isothermal diagnostic assays for the detection of soil-transmitted helminths based on the SmartAmp2 method. (cdc.gov)
  • The assays targets the hemagglutinin neuraminidase gene for each virus. (uw.edu)
  • The detection limits of these assays were not detectably compromised by the presence of the RNA control. (ox.ac.uk)
  • Two real-time RT-PCR assays targeting conserved regions of the N and 1ab genes of both viruses were developed and used in parallel. (hindawi.com)
  • Infectious virus was readily isolated from samples derived from the throat or lung, but not from stool samples-in spite of high concentrations of virus RNA. (nature.com)
  • The virus is infectious for many cancer cell lines (see below), and has oncolytic properties demonstrated in animal models and in naturally-occurring cancers in animals. (wikipedia.org)
  • There are no scientific studies, which were performed using modern detection methods, which would identify SeV as an infectious and decease causative for humans or domestic animals. (wikipedia.org)
  • open-access medical journal of scientific papers covering laboratory research data on human infectious diseases as well as its application for elucidation and management of epidemic processes. (ncipd.org)
  • We believe this represents a significant advancement in the field of infectious disease detection, with the potential to improve the testing capacity of hospital clinical laboratories worldwide. (rapidmicromethods.com)
  • However, last week Wade Stevenson, diagnostic product manager at Idaho Tech, told PCR Insider that Idaho Tech chose not to commercialize that product, instead submitting to FDA an updated version of the panel including two additional viral targets, the parainfluenza 1 and 2 viruses. (genomeweb.com)
  • In general, types 1 and 2 cause outbreaks of respiratory disease in the fall, which include colds, pharyngitis, tracheobronchitis and croup. (virology-online.com)
  • Understanding the phylogenetic factors that determine the virus transmission is important for assessing the epidemiological characteristics of the disease and predicting its possible outbreaks. (crie.ru)
  • To determine the epidemiology of human parainfluenza virus in homeless shelters during the COVID-19 pandemic, we analyzed data and sequences from respiratory specimens collected in 23 shelters in Washington, USA, during 2019-2021. (cdc.gov)
  • We evaluated IFV(influenza virus) activity during the COVID-19 pandemic and the effect of NPI intensity on influenza transmission. (bvsalud.org)
  • strong>SARS-CoV-2, the virus responsible for COVID-19 pandemic, has posed huge global health challenges. (ncipd.org)
  • The A(H1N1) is also created as A(H1N1)pdm09 as it induced the pandemic in 2009 and changed the prior A(H1N1) virus which had circulated prior to 2009. (infotrace.net)
  • It constitutes a public health concern due to the burden that it represents for the health system and labor market, and for its potential to evolve into a pandemic [ 1 - 3 ]. (biomedcentral.com)
  • Based on these findings, initial reports from clinicians [ 1 ] are consistent with seasonal fluctuations and a redistribution of cases over time during the COVID-19 pandemic. (medscape.com)
  • We employed a novel method, RT-Bst, to enrich the concentration of cDNA for subsequent multiplex PCR detection of selected RNA viruses. (westminster.ac.uk)
  • Both multiplex one-step RT-PCR and RT-Bst PCR were used to compare their performances for detection of virus sequences. (westminster.ac.uk)
  • Idaho Technology said today that it has received 510(k) clearance from the US Food and Drug Administration to market its FilmArray instrument and FilmArray Respiratory Panel, a multiplex nucleic acid test designed to simultaneously detect 15 respiratory viruses. (genomeweb.com)
  • This article discusses the alloimmune-dependent and -independent risk factors for bronchiolitis obliterans, the current understanding of the pathogenesis of bronchiolitis obliterans based on results of animal and human studies, the clinical staging of the complication, strategies that may contribute to the prevention and/or early detection of bronchiolitis obliterans, and suggestions for future research. (ersjournals.com)
  • We analyzed respiratory virus surveillance data from 2 previously described homeless shelter studies ( 3 , 4 ) conducted during October 2019‒May 2021. (cdc.gov)
  • encephalitis 2021;1(1):14-19. (encephalitisjournal.org)
  • SeV has several features that are important in a vector for a successful vaccine: the virus does not integrate into the host genome, it does not undergo genetic recombination, it replicates only in the cytoplasm without DNA intermediates or a nuclear phase and it is does not cause any disease in humans or domestic animals. (wikipedia.org)
  • The control consists of a G+C-rich (60%) RNA molecule with an extensive secondary structure, based on a modified hepatitis delta virus genome. (ox.ac.uk)
  • An internal control based on the detection of human endogenous nucleic acid sequence (RNase P) present in human genome has been employed in order to check RNA extraction, PCR inhibition and sampling or application errors. (anatoliageneworks.com)
  • Although the positive detection of SARS-CoV-2 in clinical specimens from the upper respiratory tract has previously been described 9 , 10 , these observations do not address the principal differences between SARS and COVID-19 in terms of clinical pathology. (nature.com)
  • The results from the cobas ® Paraflu 1-4 UC must be interpreted within the context of all relevant clinical and laboratory findings. (roche.com)
  • From 4 discordant positive samples (1 for HPIV1, 2 for HPIV2, 1 for HPIV4), 3 (1 for HPIV1, 1 for HPIV2, 1 for HPIV4) of these could be resolved as in agreement with the retrospective clinical status. (roche.com)
  • A SeV-based vaccine development against HIV-1 has reached a phase II clinical trial. (wikipedia.org)
  • I'd like to welcome you to today's COCA call, Clinical Management of Critically Ill Adults with Corona Virus Disease 2019, COVID-19. (cdc.gov)
  • Whereas positive SARS-CoV-2 detection in clinical specimens from the upper respiratory tract has been described 9 , these observations do not address principal differences between SARS and COVID-19 in terms of clinical pathology. (medrxiv.org)
  • Last January, the company initiated clinical trials for FilmArray RP at University of Texas Southwestern Medical Center, Detroit Medical Center, and the Medical University of South Carolina ( PCR Insider , 1/28/2010 ). (genomeweb.com)
  • This section uses Real-time PCR techniques for the detection of viral nucleic acid in clinical samples. (hslpathology.com)
  • This is primarily due to poorly characterized RNA polymerases and weak clinical activity of nucleoside analogs (ribavirin for respiratory syncytial virus [RSV] and parainfluenza). (ccjm.org)
  • BO and its clinical correlate bronchiolitis obliterans syndrome (BOS) affect up to 50-60% of patients who survive 5 yrs after surgery, irrespective of the type of transplant procedure 1 , 4 - 6 . (ersjournals.com)
  • Clinical symptoms at onset are unspecific or even absent, and many patients only present with an asymptomatic fall in FEV 1 . (ersjournals.com)
  • Campbell H., Nair H., Respiratory Virus Global Epidemiology Network None. (ox.ac.uk)
  • No common group antigen, though some degree of cross reactivity can be demonstrated with the different serotypes and the mumps virus. (virology-online.com)
  • And Dr. Alhazzani is the primary author of the Surviving Sepsis Campaign: rapid guidelines on the management of critically ill adults with Corona virus disease 2019. (cdc.gov)
  • Use of a Luminex xTAG RVP Fast kit showed that coinfection with respiratory syncytial virus and parainfluenza 3 virus was common among patients infected with either virus type. (hindawi.com)
  • In these vaccines, the safe viral vectors are used to deliver protectively significant immunogens of pathogenic viruses. (crie.ru)
  • These findings were compared with routine laboratory detection. (westminster.ac.uk)
  • After the Games, the other swab was tested for 16 possible causative respiratory viruses using PCR in laboratory-based testing. (bmj.com)
  • An analysis by mask use showed ILI (RR=6.64, 95% CI 1.45 to 28.65) and laboratory-confirmed virus (RR=1.72, 95% CI 1.01 to 2.94) were significantly higher in the cloth masks group compared with the medical masks group. (bmj.com)
  • Newcastle disease virus is a rubulavirus that infects poultry, penguins, and other birds and has been responsible for conjunctivitis in bird handlers and laboratory workers. (medscape.com)
  • Importantly, not only did these studies identify previously unrecognised viral species, but they also consistently observed an abundance of viruses not part of the regular veterinary diagnostic laboratory detection range, including influenza D virus (IDV), bovine rhinitis viruses A and B (BRAV and BRBV), parvoviruses and bovine herpesviruses other than bovine alphaherpesvirus-1 (BoHV-1). (biomedcentral.com)
  • 8.1 Laboratory surveillance and biosafety: human. (who.int)
  • Bronchiolitis obliterans (BO) after LTx was first described in 1984 at Stanford University, Stanford, CA, USA, in heart-lung transplant recipients who showed a progressive decline inforced expiratory volume in one second (FEV 1 ) 3 . (ersjournals.com)
  • Community-based screening of hepatitis C with a one-step RNA detection algorithm from dried-blood spots: analysis of key populations in Barcelona, Spain. (cdc.gov)
  • The unusual structure of hepatitis delta virus RNA has previously been shown to enhance its stability and resistance to nucleases, an advantage for routine use as an internal control. (ox.ac.uk)
  • Influenza A virus is a main cause of winter epidemics that results in increments in respiratory morbidity. (biomedcentral.com)
  • former SFTS virus, SFTSV) was identified, the epidemics of severe fever with thrombocytopenic syndrome (SFTS) caused by this virus have occurred in several countries in East Asia. (crie.ru)
  • since 1968, most seasonal influenza epidemics have been caused by H3N2 (an influenza A virus). (msdmanuals.com)
  • Influenza B viruses may cause milder disease but often cause epidemics with moderate or severe disease, either as the predominant circulating virus or along with influenza A. (msdmanuals.com)
  • Most influenza epidemics are caused by a predominant serotype, but different influenza viruses may appear sequentially in one location or may appear simultaneously, with one virus predominating in one location and another virus predominating elsewhere. (msdmanuals.com)
  • 1. Centers for Disease Control and Prevention. (roche.com)
  • Rapid antigen detection kits can provide results within hours, making them useful in the emergency department. (medscape.com)
  • Viral-antigen detection is one of the new tests, but the results are generally less sensitive and less specific than those of conventional cell cultures. (medscape.com)
  • In adults, the virus is usually limited to causing inflammation in the upper parts of the respiratory tract. (virology-online.com)
  • Pharyngeal virus shedding was very high during the first week of symptoms, with a peak at 7.11 × 10 8 RNA copies per throat swab on day 4. (nature.com)