• Conifer seed oils from European Larch (Larix decidua), Norway Spruce (Picea abies) and European Silver Fir (Abies alba) have been analyzed by non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) with atmospheric pressure chemical ionisation (APCI)-MS detection. (unboundmedicine.com)
  • Zare and his students have also developed cavity ring-down spectroscopy (CRDS) for quantitative diagnosis, and for high performance liquid chromatography (HPLC) Zare is also involved in the development of desorption electrospray ionization (DESI) techniques, which are being used for mass spectrometric imaging of lipids, metabolites and proteins in tissue samples, including prostate cancer. (wikipedia.org)
  • The test principle utilizes high performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry (HPLC-APPI-MS/MS) for the quantitative detection of genistein, daidzein, equol, O-desmethylangolensin, enterodiol, and enterolactone. (cdc.gov)
  • High pressure liquid chromatography (HPLC) with fluorescence detection seems to be the most effective analytical method for the determination of indole. (nofima.no)
  • Various methods such as polarography, piezoelectric crystals, high-pressure liquid chromatography (HPLC) with flame ionization (FID), electrochemical (EC), or ultraviolet (UV) detector, linear sweep voltammetry (LSV), GC with thermal energy analyzer (TEA), FID, or ECD, and thin-layer chromatography (TLC) have been investigated for detecting propylene glycol dinitrate in environmental samples. (cdc.gov)
  • High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) has been employed to determine neurotransmitters levels due to its distinct advantages. (knaw.nl)
  • High-pressure liquid chromatography (HPLC) analysis with detection at 400 nm showed a loss of heme comparable to the activity loss, but a modified heme was not detected. (aspetjournals.org)
  • Using the honey bee as a model, we directly compare the leading current methods of using High Performance Liquid Chromatography (HPLC) with an evaporative light-scattering detector and Gas Chromatography coupled with Mass Spectrometry (GC-MS) to determine which method would be better for measuring trehalose, glucose, and fructose in terms of reproducibility, accuracy, and sensitivity. (sabanciuniv.edu)
  • 1) in the first part of the study, the analytical methods examined were isocratic high pressure liquid chromatography (HPLC) with ultraviolet (UV) detection, capillary gas chromatography (GC) with temperature programming and flame ionisation detection and gas chromatography-mass spectrometry (GC-MS). Twelve NSAIDs in common use in the UK were selected as test compounds for the evaluation of the separating ability, selectivity and sensitivity of detection of the three methods. (gla.ac.uk)
  • In addition, fluorescence spectrometry and electrochemical detection (ECD) were examined to assess their value as additional HPLC detection systems which might increase the selectivity or sensitivity of the method. (gla.ac.uk)
  • Here we describe a liquid-chromatographic method coupled with tandem mass spectrometry (LC-MS/MS) and we present the results of its comparison with a high-performance liquid-chromatographic method with electrochemical detection (HPLC-ECD). (unimi.it)
  • Direct glutathione quantification in human blood by LC-MS/MS : comparison with HPLC with electrochemical detection / I. Squellerio, D. Caruso, B. Porro, F. Veglia, E. Tremoli, V. Cavalca. (unimi.it)
  • HPLC systems provide rapid analysis of mixtures and the production of high quality purified materials, particularly where classical separation methods are unsuccessful. (leeds.ac.uk)
  • The presence of HMW species, for instance, is frequently determined using size-exclusion chromatography (SEC) coupled with high-pressure liquid chromatography (HPLC) or ultra-high performance liquid chromatography (UHPLC), while LMW species are detected using a capillary electrophoresis-sodium dodecyl sulfate (CE-SDS) (reduced and non-reduced) technique. (pharmtech.com)
  • Humic substances are classified into three derived phenols generated by CuO oxidation are based on subcategories: humin, humic acid, and fulvic acid, based on GC-MS, HPLC with diode array detection (DAD) and CE- extractability at different pH values [3]. (lu.se)
  • Zare is well known for his research in laser chemistry, particularly the development of laser-induced fluorescence, which he has used to study reaction dynamics and analytical detection methods. (wikipedia.org)
  • Early in his career, the question of whether laser-induced fluorescence (LIF) could be used to study aflatoxins spurred Zare to adapt LIF for use on liquids. (wikipedia.org)
  • Additional selectivity is obtained through the use of fluorescence detection. (nih.gov)
  • For all samples, a fully validated high-pressure liquid chromatography procedure with fluorescence detection was used. (erowid.org)
  • The consistency of response by ultraviolet (UV) and fluorescence detection in a series of urea derivatives prepared from 9- methylamino-methylanthracene (73356191) (MAMA) and 11 isocyanate compounds was evaluated. (cdc.gov)
  • The authors conclude that the use of MAMA as a derivatizing agent, along with analysis by high pressure liquid chromatography with UV absorbance and fluorescence detection offered a promising approach to the identification and quantitation of airborne total reactive isocyanate group. (cdc.gov)
  • UV , fluorescence and evaporative light scattering detection available. (leeds.ac.uk)
  • The new ultra-high performance super- critical fluid chromatography method was also applied for the qualitative and quantitative analysis of lignin-derived phenolic compounds obtained upon alkaline cupric oxide oxida- tion of a commercial humic acid. (lu.se)
  • Digested peptides from clinical samples were processed by PRISM (high pressure and high resolution separations coupled with intelligent selection and multiplexing), which incorporates high pH reversed-phase liquid chromatography (LC) separations to fractionate and select target fractions for follow-on LC-selected reaction monitoring (LC-SRM) analyses. (nih.gov)
  • This opened up the potential for a wide variety of fluid applications, including the detection of single molecules in liquids at room-temperature and detection methods for capillary electrophoresis. (wikipedia.org)
  • Our high quality photon solutions of wavelengths from ultraviolet to infrared provide higher economic efficiency, improved process reliability and more innovation in your industrial, scientific and medical applications. (learnew-led.com)
  • We studied the determination of phenylpropionylglycine in urine by isocratic ion-exclusion chromatography on a cation-exchange column using water-sulphuric acid (pH values between 2 and 4) as mobile phase. (nih.gov)
  • The limit of quantification (also called the limit of quantification) has a higher concentration. (labsupport.at)
  • Evaluation of a suspected hemoglobinopathy should include electrophoresis of a hemolysate to detect abnormal hemoglobins and quantification of HbA 2 and HbF with column chromatography. (medscape.com)
  • Deficiency of medium-chain acyl-CoA dehydrogenase is a frequent and treatable metabolic defect, which can be diagnosed by detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid. (nih.gov)
  • We conclude that, even in asymptomatic patients, determination of phenylpropionylglycine in urine after a phenylpropionic acid load by ion-exclusion chromatography is a rapid and reliable diagnostic tool for the detection of medium-chain acyl-CoA dehydrogenase deficiency. (nih.gov)
  • This selective method allows for rapid detection of phytoestrogens in human urine with limits of detection in the low parts per billion (ng/mL) range. (cdc.gov)
  • The primary method of analysis for propylene glycol dinitrate and its metabolites in blood and urine is gas chromatography with electron capture detection (Litchfield 1968). (cdc.gov)
  • The purpose of this study was to develop a screening procedure for the detection of non-steroidal anti-inflammatory drugs (NSAIDs) in the urine of the racing greyhound. (gla.ac.uk)
  • 2) The second part of the study established the normal pattern of organic acids present in greyhound urine, which would be co-extracted with any NSAIDs present and might lead to interference in the detection and quantitation of the drugs. (gla.ac.uk)
  • Validation studies proved that the chromatographic method had good repeatability, reproducibility and limit of detection. (url.edu)
  • Additionally, analytical methods may be included that refine previously used methods to obtain lower detection limits, and/or to improve accuracy and precision. (cdc.gov)
  • Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. (hud.ac.uk)
  • These are gas chromatography (GC) with electron capture detector (ECD) (Horvath et al. (cdc.gov)
  • An integrated ion liquid chromatography chip is demonstrated, which has on-chip column, filters, injection structure, and conductivity detector. (caltech.edu)
  • In 2003-2004 high performance liquid chromatography electrospry ionization mass spectrometric (LC-ESI-MS/MS) detection (Rybak, M. E. et al. (cdc.gov)
  • However, neurotransmitter detection still presents some challenges. (knaw.nl)
  • The goal of this work was to develop a method for time and position simultaneous deep brain stimulation (DBS) and neurotransmitter detection in an in vivo animal model. (uni-luebeck.de)
  • Extracts were purified through selective diol-bonded silica cartridges, replacing the usual laborious liquid-liquid partitioning procedure. (url.edu)
  • The implications of the results with respect to the detection of these five drugs and the interpretation of their concentrations during a screening procedure at a race meeting are discussed. (gla.ac.uk)
  • Detection principles based on molecule spectroscopy and mass spectroscopy. (kau.se)
  • Improved detection, versatility, and sensitivity for protein complex subunit analysis and biopharmaceutical characterization with an extended optional mass range up to m/z 16,000. (thermofisher.com)
  • This work describes the methodology for the analysis of terfenadine and the acid metabolite of terfenadine in plasma using high-performance liquid chromatography. (nih.gov)
  • Background: Recently, Denaturing High-Performance Liquid Chromatography (DHPLC) has been widely used for mutation detection hMLH1 and hMSH2 genes due to reduced cost of analysis, accuracy, and high sample throughput. (elsevierpure.com)
  • Alkaline cupric oxide (CuO) oxidation is one of the mostly performance supercritical fluid chromatography (UHPSFC) adopted methods for analyzing lignin in various complex using columns with sub-2 m packing can further improve environmental matrices such as soils and sediments [9]. (lu.se)
  • UHPSFC , ultra- pacted by other parameters, such as the addition of the mod- high performance supercritical fluid chromatography ifier and the change of the mobile phase density [20]. (lu.se)
  • Considering the substantial differences in concentrations in blood samples taken from various sites in the body and the high levels in some tissues e.g., in liver, we concluded that the influence of postmortem redistribution should be taken into account in the interpretation of toxicological data when an appropriate peripheral sample cannot be obtained or when blood samples are not available because of putrefaction. (erowid.org)
  • Morphine was purified in lobster tissues via high pressure liquid chromatography coupled to UV detection. (nel.edu)
  • Some Considerations on Quantitative Methodology and Detection Limits i. (erowid.org)
  • 2,4-Toluene- diisocyanate (584849) had detectable limits of 18.7 micrograms/cubic meter (microg/m3) and 4,4'-methylenediphenyl- isocyanate (101688) had a detection limit of 15.7microg/m3 in a 50 liter sample volume. (cdc.gov)
  • Limits of detection were about 0.06 mg/kg. (url.edu)
  • The major anionic head groups can be quantified in single runs with practical detection limits of about 100 pmol, and the D3 isoforms of phosphatidylinositol phosphate (PIP) and PIP 2 are detected as shoulder peaks. (elsevierpure.com)
  • abstract = "Background: β-thalassemia major is a severe disease with high morbidity. (tau.ac.il)
  • Journal of Chromatography. (unboundmedicine.com)
  • AU - Lísa,Miroslav, AU - Holcapek,Michal, AU - Rezanka,Tomás, AU - Kabátová,Nadezda, Y1 - 2007/02/06/ PY - 2006/09/04/received PY - 2007/01/23/revised PY - 2007/01/25/accepted PY - 2007/2/20/pubmed PY - 2007/5/1/medline PY - 2007/2/20/entrez SP - 67 EP - 77 JF - Journal of chromatography. (unboundmedicine.com)
  • He is a member of the editorial advisory boards of other scientific publications, among them Chemistry World, Angewandte Chemie, Central European Journal of Chemistry, Journal of Separation Sciences and the Chinese Journal of Chromatography. (wikipedia.org)
  • Journal of Chromatography A , 778 (1-2), 95-101. (url.edu)
  • On-chip sample injection, separation, and detection of seven common anions are successfully demonstrated with a sensitivity of 1 ppm. (caltech.edu)
  • Gradient separation at a pressure of 450 psi and on-line MS detection of digested cytochrome c protein is successfully performed. (caltech.edu)
  • The high separation power and short analysis time obtained demonstrate for the first time that supercritical fluid chromatography is a fast and reliable technique for the analysis of lignin-derived phenols in complex environmental samples. (lu.se)
  • They have explored a wide-ranging variety of problems in physical chemistry and chemical analysis including examination of heterogeneous structures in mineral samples, the contents of cells and subcellular compartments, and the chemical analysis of liquid samples. (wikipedia.org)
  • Work with postdoc Gerald Diebold resulted in the first use of LIF for detection in chemical analysis. (wikipedia.org)
  • Multiple fragmentation techniques - CID and HCD with optional UVPD, ETD, PCTR - are available at any stage of MS, with subsequent mass analysis in either the ion trap or ultra-high resolution Orbitrap mass analyzer. (thermofisher.com)
  • TGs containing Delta5-UPIFAs have a higher retention in comparison with common TGs found in plant oils with single methylene interrupted Delta6(9)-FAs and also significantly changed relative abundances of fragment ions in APCI mass spectra. (unboundmedicine.com)
  • Phenylpropionylglycine, phenylpropionic acid and hippuric acid exhibited high retention factors with only a slight decline at increasing solvent pH. (nih.gov)
  • The use of azole fungicides provides selective pressure for the development of azole resistance among species in soils. (cdc.gov)
  • Quantify more samples with TMTpro 18plex multiplexing using intelligent acquisition with faster scanning data acquisition for higher sample throughput, single cell proteomics, and post-translational modifications (PTMs). (thermofisher.com)
  • The consumption of diets high in phytoestrogen-rich foods has been associated with lower rates of hormone-dependent cancers (Peeters et al. (cdc.gov)
  • A His -or Strep-tag II can be added to either terminus, greatly simplifying protein purification and detection after expression. (qiagen.com)
  • The most common protein-based impurities that downstream processes are developed to control include high- and low-molecular-weight species, charge-variants, and host-cell proteins. (pharmtech.com)
  • As a result, CE-SDS is used for the detection of LMW protein impurities. (pharmtech.com)
  • When compared with the results obtained using a reference impinger method in laboratory sampling, the isocyanate air concentrations recorded from the coated filter method were higher. (cdc.gov)
  • When tested in the field, air concentrations determined from the impinger samplers for more than 50 percent of the sample pairs were higher than those obtained by the filter sample method. (cdc.gov)
  • The lower detection limit of the MS method was less than 1 mg/m3 propylene glycol dinitrate in air, but no information on accuracy and precision was reported. (cdc.gov)
  • High indole levels in frozen shrimp can be considered an indicator of poor product quality prior to freezing and thus of hygienic practices far away from Good Hygienic Practice (GHP). (nofima.no)
  • Human cells were labeled with TMTpro 18plex reagents, combined, fractionated, and subsequently 12 high pH fractions were analyzed using 75 min gradient with SPS MS3 Real-Time Search methods. (thermofisher.com)
  • Thus, MEHP and perhaps 2-EHA and other di-carboxylic acid concentrations in the body were higher in mice or rats than marmosets when the same dose of DEHP was administered (Ito et al. (who.int)
  • Shrey Patel, senior in LAS studying chemical engineering and on the pre-med track at the University, has been breaking ground in the research of early detection of Alzheimer's disease - despite pandemic-related disruptions. (dailyillini.com)
  • During his junior year, he began his research by investigating the early detection of Alzheimer's disease. (dailyillini.com)
  • Patel works in the Mirica Group, where he is in the process of developing diagnostic and therapeutic compounds for the early detection of Alzheimer's. (dailyillini.com)
  • Now that he is back in the lab, he has shifted his focus back to developing the compounds for early detection. (dailyillini.com)
  • Although there are numerous studies exploring ultrasound and biomarker prediction of patients at risk of pre-eclampsia, other than early detection of preeclampsia , no reliable test or symptom complex predicts the development of eclampsia. (medscape.com)
  • The detection of neurotransmitters has extensively been applied to the study of the pathogenesis, diagnosis, and therapeutic effect of drugs on many neuropsychiatric diseases. (knaw.nl)
  • The detection of neurotransmitters in these samples was successful. (uni-luebeck.de)
  • However, major benefits of LC-MS/MS are the improved selectivity, precision and accuracy, the higher sensitivity and the unaltered capacity of detection with time in contrast to ECD. (unimi.it)
  • Residual undesired proteins-host-cell proteins (HCPs) and high-molecular-weight (HMW) and low-molecular-weight (LMW) species-have the potential to affect the safety and efficacy of biopharmaceuticals. (pharmtech.com)
  • Mean Hcy level was significantly higher in the test group. (who.int)
  • P. O. Box 124, SE-22100 Lund, Sweden with high efficiency. (lu.se)
  • Integrated liquid chromatography (LC) chips are valued because of their significant advantages over conventional systems. (caltech.edu)