These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups. (drugbank.com)
Inspection of these structures ( I-VI ) reveals that all possess an aromatic moiety and terminal amine binding sites. (healthdrugpdf.com)
In the crystal, molecules form centrosymmetric dimers through R22(8) hydrogen-bonded rings involving the amine and one carbonyl group of the quinazolinedione moiety. (uanl.mx)
Alkyl5
According to the company's draft red herring prospectus, Clean Science and Technology , Alkyl Amines Chemicals, Tatva Chintan Pharma and Neogen Chemicals are its listed peers. (equitymaster.com)
To avoid drug abuse, 32 substances have been controlled in Japan since April in 2007 by the Pharmaceutical Affairs Law as designated substances Shitei-Yakubutsu, classified as 11 tryptamines, 11 phenethylamines, 2 piperazines, 6 alkyl nitrites, 1 diterpene and 1 plant. (erowid.org)
In addition the alkyl side chain is ethyl or substituted ethyl at α- or β-carbon by methyl group .The length of the alkyl chain that separate the terminal amine from the ether oxygen atom of the aryloxy group is of major importance and two-carbon chain appears optimal. (healthdrugpdf.com)
These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an alkyl group. (hmdb.ca)
A series of 2-chloro-5-[(4-chlorophenyl)sulfamoyl]- N -(alkyl/aryl)-4-nitrobenzamide derivatives (5a - 5v) has been synthesized and confirmed by physicochemical(R f , melting point) and spectral means (IR, 1 HNMR, 13 CNMR). (biomedcentral.com)
Ethylene amines2
This process gives a variety of amines, especially ethylene amines which are separated by distillation and sublimation. (wikipedia.org)
20. The process according to claim 12, wherein TETA or diethylenetriamine (DETA) and optionally further ethylene amines which are comprised as by-products in the reaction product obtained in each case are isolated after the hydrogenation. (patentsencyclopedia.com)
Tertiary amines1
In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence enables alcohols to be converted directly into both secondary and tertiary amines. (organic-chemistry.org)
Secondary amines4
Imines and secondary amines were synthesized selectively by a Pd-catalyzed one-pot reaction of benzyl alcohols with primary amines. (organic-chemistry.org)
The oxidation of secondary amines to imines or ketimines is facilitated with the help of Ag 2 CO 3 as cocatalyst. (organic-chemistry.org)
Iron-catalyzed aerobic oxidative reactions of primary amines, secondary amines, benzylamines with anilines, and alcohols with amines in the presence of air as the economic and safe oxidant, provide several direct, practical, and greener approaches for the preparation of useful imines. (organic-chemistry.org)
This step would rely on the recently disclosed nickel-catalysed amide bond cleavage that has only seen limited use in esterification and the Suzuki-Miyaura coupling.18,19 Interception of this intermediate with primary or secondary amines 2 would furnish the desired product 3. (docksci.com)
Synthesis5
A base-mediated protocol enables the synthesis of imines and amines from N -phenylureas and alcohols in good yields under air. (organic-chemistry.org)
This protocol is as an efficient alternative to conventional methods for the synthesis of imines and amines. (organic-chemistry.org)
The Tungsten-Promoted Synthesis of Piperidyl-Modified erythro-Methylphenidate Derivatives. (acs.org)
Synthesis, Fluorine-18 Radiolabeling, and Biological Evaluation of N-((E)-4-Fluorobut-2-en-1-yl)-2β-carbomethoxy-3β-(4′-halophenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the BrainDopamine Transporter with Positron Emission Tomography. (acs.org)
An efficient and environmentally benign method has been developed for the synthesis of 5-arylidine-2-(methylthio)-thiazolones derivatives using Alum [KAl(SO 4 ) 2 ·12H 2 O] catalyst and triethyl amine in water under microwave irradiation. (eurjchem.com)
Morpholine1
A set of promising moieties (piperidineethanol, quinuclidine, TMEDA, and methyl derivatives of diethanolamine, imidazole, morpholine and piperazine) had similar [Au]R/Cm values to the commercial IEX resins Dowex-1, IRA-410 and Amberlite A26 (-10 mmol/mol). (edu.au)
Aromatic2
TETA, like other aliphatic amines, react quicker and at lower temperatures than aromatic amines due to less negative steric effects since the linear nature of the molecule provides it the ability to rotate and twist. (wikipedia.org)
Neat non-volatile amines react efficiently with various aromatic aldehydes in the absence of any catalyst or solvent, to give imines after a reaction time of eight minutes under microwave irradiation. (organic-chemistry.org)
Speciality Chemicals1
Balaji Speciality Chemicals (BSCL) is a subsidiary of Balaji Amines (BAL) , one of the leading manufacturers of aliphatic amines in India. (equitymaster.com)
2HCL5
Find complete chemical information for 1-(METHYL-D3)PIPERAZINE 2HCL . (clearsynth.com)
1-(Methyl-D3)piperazine 2HCl, a remarkable chemical compound, is characterized by its deuterium-labeled methyl group and its association with piperazine, a bicyclic heterocyclic amine. (clearsynth.com)
1-(METHYL-D3)PIPERAZINE 2HCL in Bulk is primarily used in Pharmaceutical Industry and Drug Discovery. (clearsynth.com)
This page contains information about 1-(METHYL-D3)PIPERAZINE 2HCL. (clearsynth.com)
You can buy 1-(METHYL-D3)PIPERAZINE 2HCL from Clearsynth at best competitive price with assured price guarantee. (clearsynth.com)
Compounds5
Methods for the determination of isocyanate compounds in air typically involve derivatization of the isocyanate species with an amine reagent and analysis of the derivatized isocyanate s by high-performance liquid chromatography (HPLC). (cdc.gov)
This invention relates to novel deuterated compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. (justia.com)
The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. (allindianpatents.com)
Abstract: The aim of this study was to synthesize, characterize, and evaluate neoteric imine compounds for antimicrobial activity and hemocompatibility.Four compounds were synthesized using 3-thiophene carboxaldehyde, ethanol, amine , and acetic acid. (docslib.org)
Tris(2,2,2-trifluoroethyl)borate [B(OCH 2 CF 3 ) 3 ] is a mild and general reagent for condensation of amides or amines with carbonyl compounds providing N -Sulfinyl, N -toluenesulfonyl, N -(dimethylamino)sulfamoyl, N -diphenylphosphinoyl, N -(α-methylbenzyl), and N -(4-methoxyphenyl) aldimines at room temperature. (organic-chemistry.org)
Aryl1
Modeling studies demonstrate that aryl piperazines ( I ), Aryloxyalkylamines ( II ), phenylalkykamines ( III ) and indolylalkylamines ( VI ) might interact at 5-HT receptors in a similar manner. (healthdrugpdf.com)
Reagent3
9-Anthracenylmethyl1-piperazine carboxylate (PAC) is a newly developed derivatizing reagent designed to enable much simpler total isocyanate analysis. (cdc.gov)
A number of methods used 9-(N-methylaminomethyl)anthracene as a reagent to derivatize the HDI allowing subsequent detection of a stable derivative by UV absorbance or fluorescence detection (Andersson et al. (cdc.gov)
The 1-(2-methoxyphenyl)- piperazine used as a derivatization reagent in the NIOSH methods was also used on a sorbent (Schmidtke and Seifert 1990) and inert supports (Huynh et al. (cdc.gov)
Isocyanate1
Like other amine reagents, it reacts rapidly with isocyanate s to form stable derivatives, enabling HPLC analysis of monomers or other specific isocyanate species. (cdc.gov)
Benzyl1
Comparison between the various methyl and benzyl- derivatives showed that gold loading was relatively insensitive to the steric bulk of the functional group. (edu.au)
Primary1
The classical in batch synthetic pathway of this class of derivatives consists of four steps involving the alkylation of commercially available phenols in biphasic conditions, nucleophilic substitution of Boc-protected alicyclic amines, removal of the protecting group, and sulfonylation of the producing primary amine in an alkaline environment (Plan 1). (abic2004.org)
Nucleophilic1
The reaction would be driven thermodynamically by the liberation of the N-functionalized amine 7, which would be less nucleophilic than amine 2 undergoing transamidation. (docksci.com)
DETA1
In India, BSCL is the sole manufacturer of niche chemicals such as Ethylene Diamine (EDA), Diethylenetriamine (DETA), Aminoethyl ethanolamine (AEEA) and Aminoethyl Piperazine (AEP), using the Monoethanol Amine (MEA) process. (equitymaster.com)
Stereoisomers1
To date phenytoin, some benzazepine derivatives and stereoisomers of methylphenylpiracetam have been reported as PAMs of Sig1R while NAMs of Sig1R have not yet been described. (frontiersin.org)
Catalyst1
A modular aerobic oxidation of amines to imines has been achieved using an ortho -naphthoquinone ( o -NQ) catalyst. (organic-chemistry.org)
Reaction2
However, PAC derivatives also undergo a cleavage reaction under mild, but selective, conditions to generate the same single analyte for all species. (cdc.gov)
A common reaction scheme was employed for most preparations, via treatment of the exhaustively chloromethylated resin substrate with excess amine in dimethylformamide. (edu.au)
TETA1
The branched isomer tris(2-aminoethyl)amine and piperazine derivatives may also be present in commercial samples of TETA. (wikipedia.org)
Derivatization1
Another derivatization agent used was 1-(2-pyridyl)piperazine either in a toluene solution (Ellwood et al. (cdc.gov)
Acid1
X-ray structure of Sitagliptin with DPP-IV indicated hydrophobic interaction of the triazolo-piperazine ring system with the S2 pocket through the amino acid Phe357. (ommegaonline.org)
Amino2
As indicated below, such hydrogenation processes are also known for various amino nitrites for producing some amines. (patentsencyclopedia.com)
The current research aimed to design molecules maintaining the β-amino amide pharmacophore of Sitagliptin, but with the triazolo-piperazine ring system replaced by more lipophilic entities for better hydrophobic interactions with Phe 357 in the S2 pocket. (ommegaonline.org)
Thereof1
The invention relates to 1-piperazine- and 1-homopiperazine-carboxylate derivatives, and to the preparation and therapeutic application thereof. (allindianpatents.com)
Invention relates2
In particular, this invention relates to novel substituted xanthine derivatives that are deuterated derivatives of a pentoxifylline metabolite. (justia.com)
For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentoxifylline. (justia.com)
Group2
The n-propyl chain links the quinazolinedione heterocycle and the phenylpiperazine group in which the benzene ring is equatorially located and the piperazine ring has the expected chair conformation. (uanl.mx)
X-ray crystal structure of Sitagliptin bound to DPP-IV, (Figure-2), illustrates that the triazolo-piperazine fragment of the drug is oriented towards the Phe357 residue in the catalytic site, and the trifluromethyl group towards the Ser209 residue. (ommegaonline.org)
Pharmaceutical1
This unique isotopically labeled derivative of piperazine holds significant importance in various scientific and pharmaceutical applications. (clearsynth.com)
Form2
[0002] It is generally known that aliphatic nitrites, which may be substituted by further functional groups, can be hydrogenated in the presence of catalysts to form the corresponding amines. (patentsencyclopedia.com)
I reacted with PCl 5 to give the 11, 11-dichloro derivative (VI) and with hydroxylamine to form its oxine (VII). (go.jp)
Methods1
Methods for the biological monitoring of exposures to HDI have been based on determination of the corresponding amine, hexamethylene diamine. (cdc.gov)
Range1
The reactions did not require any additives and were effective for a wide range of alcohols and amines. (organic-chemistry.org)
Samples1
The pure freebase is a colorless oily liquid, but, like many amines, older samples assume a yellowish color due to impurities resulting from air-oxidation. (wikipedia.org)