• It is suggested that since alcoholism treatment outcome is related to neuropsychological status, rehabilitation of cognitive functioning may improve treatment success. (usf.edu)
  • SGT11 restored cognitive, sensorimotor, and neurological function. (figshare.com)
  • Unfortunately, leaving nonstandard work schedules does not necessarily guarantee a quick return to normal cognitive functioning. (cdc.gov)
  • Thus, chronic exposure to PCP can produce time-dependent regulation of CYP2C11-mediated metabolism of endogenous and exogenous compounds. (aspetjournals.org)
  • Because leucine contributes to glutamine synthesis, taking supplemental leucine before and after intense training and between meals can help to normalize glutamine levels in both the serum and muscle, thereby promoting anticatabolic muscle metabolism as well as supporting immune function. (getbig.com)
  • Once a patient is medically stable, the focus of their recovery shifts to rehabilitation. (wikipedia.org)
  • Context Recovery of seated balance is a rehabilitation priority for people with motor-complete spinal cord injury (mcSCI). (researchgate.net)
  • Traditionally, centre-based cardiac rehabilitation programmes are offered to individuals after cardiac events to aid recovery and prevent further cardiac illness. (bvsalud.org)
  • The primary goals of this sub-acute phase of recovery include preventing secondary health complications, minimizing impairments, and achieving functional goals that promote independence in activities of daily living. (wikipedia.org)
  • Kinetic analysis of enzyme inactivation in hepatocytes was used to describe the effect of these time-dependent inhibitors and derive the inhibition parameters k inact and K I , which generally were in good agreement with the values derived using recombinant P450s and human liver microsomes (HLMs). (aspetjournals.org)
  • This work demonstrates that caution is warranted in the interpretation of enzyme induction studies with metabolically stable, weak time-dependent inhibitors, which may have dramatic inhibitory effects on P450 activity in this system. (aspetjournals.org)
  • Mechanism-based P450 inhibitors can be characterized as displaying NADPH-, concentration-, and time-dependent quasi-irreversible or irreversible inactivation because of chemical modification of the heme and/or protein, and the inactivation rate is diminished in the presence of a competing substrate ( Silverman, 1998 ). (aspetjournals.org)
  • Haspin inhibitors did not obviously affect phosphorylation of histone H3 at serine-10 (H3S10ph) by Aurora B on chromosome arms but, in Aurora B reactivation assays, recovery of H3S10ph was delayed. (harvard.edu)
  • Haspin inhibitors did not block Aurora B localization to the spindle midzone in anaphase or Aurora B function in cytokinesis. (harvard.edu)
  • We hypothesized the efficacy of novel TNF receptor (TNF-R) inhibitors could be screened using post-traumatic sleep and that these novel compounds would improve functional recovery following diffuse TBI in the mouse. (figshare.com)
  • Renal Toxicity: Monitor renal function in patients with renal or hepatic impairment, heart failure, dehydration, or hypovolemia. (drugs.com)
  • renal adenosine A1 receptor activation during the renal ischemia-reperfusion injury is detrimental to renal function. (eurekamag.com)
  • Every year, thousands of people restore their lost function and mobility or recover from injuries through successful orthopedic surgery. (kellysearch.com)
  • However, DataNumen provides a powerful SQL recovery resource that can repair and recover integral files and the coding structure. (datanumen.com)
  • The amount of time it takes to recover is largely dependent on things like the extent of your procedure, your age, and your overall health. (interimhealthcare.com)
  • RSA verification recovery in the EVP_PKEY_verify_recover function in OpenSSL 1.x before 1.0.0a, as used by pkeyutl and possibly other applications, returns uninitialized memory upon failure, which might allow context-dependent attackers to bypass intended key requirements or obtain sensitive information via unspecified vectors. (gentoo.org)
  • The generic recovery/reset mechanisms have their own security issues -- how secure is the back-up authentication systems? (mail-archive.com)
  • setting can speed up operations that can be easily recovered outside of the database recovery mechanisms, but it can negatively affect media recovery and standby databases. (oracle.com)
  • The aim of my PhD was to investigate mechanisms underlying experience- and activity-dependent plasticity during stroke recovery. (lu.se)
  • Finally, PCAF is necessary for conditioning-dependent axonal regeneration and also singularly promotes regeneration after spinal cord injury. (nature.com)
  • We found that p300/CBP-associated factor (PCAF)-dependent acetylation of histone 3 lysine 9 (H3K9ac), paralleled by a reduction in methylation of H3K9 (H3K9me2), occurred at the promoters of select genes only after PNS axonal injury. (nature.com)
  • In addition, we observed that extracellular signal-regulated kinase (ERK) axonal retrograde signalling is required for PCAF-dependent acetylation at these promoters and for their enhancement in gene expression. (nature.com)
  • The initial severity of impairments and individual characteristics, such as motivation, social support, and learning ability, are key predictors of stroke recovery outcomes. (wikipedia.org)
  • Unit Learning Outcomes * LO32: Describe the usefulness of functions in computer programs. (majortests.com)
  • The outcomes were upper limb sensorimotor function, health-related quality of life, level of independence, cardiovascular effects, and adverse events. (karger.com)
  • Potential loss scenarios are be identified during a risk assessment which is dependent on the BIA assessment. (e-janco.com)
  • Data collection is continuing, but preliminary results are as follows: From January to October 2013, 154 firefighters (72% never-smokers) with normal pre-9/11 spirometry, who had BHR measurements within 2 years of 9/11/2001, underwent full lung function testing and repeat assessment of BHR. (cdc.gov)
  • Hematopoietic recovery was assessed through measurement of complete blood counts, lymphocyte subpopulation analysis, and thymus function assessment. (cdc.gov)
  • The 'most important password problem' is very much context-dependent. (mail-archive.com)
  • Self-managed' is context-dependent. (mail-archive.com)
  • The Cryptographic Message Syntax (CMS) implementation in crypto/cms/cms_asn1.c in OpenSSL before 0.9.8o and 1.x before 1.0.0a does not properly handle structures that contain OriginatorInfo, which allows context-dependent attackers to modify invalid memory locations or conduct double-free attacks, and possibly execute arbitrary code, via unspecified vectors. (gentoo.org)
  • We posit that angiogenesis may be an important factor that promotes neurogenic upregulation following hippocampal neuronal loss, and both factors, angiogenesis and neurogenesis, can contribute to the adaptive response of the brain for behavioral recovery. (nih.gov)
  • These data suggest that continuous PCP infusions initially decrease CYP2C11 function and protein expression by a pretranslational mechanism, but continued exposure to PCP leads to metabolic adaptation without the recovery of mRNA levels. (aspetjournals.org)
  • Furthermore, the presistence of ara-C residues in DNA inhibits recovery of DNA synthesis following exposure to drug. (aspetjournals.org)
  • GO induced DNA damages were size and dose dependent, in both exposure scenario. (biomedcentral.com)
  • A multiparametric correlation analysis of our repeated exposure data revealed that transient or persistent inflammation and oxidative stress were associated to either recovery or persistent DNA damages. (biomedcentral.com)
  • The severity of response and speed of recovery were dependent on exposure concentrations and duration of exposure. (cdc.gov)
  • Did bronchial reactivity influence the course of recovery or worsening function after WTC exposure? (cdc.gov)
  • Did corticosteroid treatment influence the course of recovery or worsening function after WTC exposure? (cdc.gov)
  • Post-exposure corticosteroid treatment ameliorated some of the excess lung function decline. (cdc.gov)
  • This study investigated hematopoietic recovery and immune function in rhesus macaques Cross-sectionally (at a single time point) 2 to 5 years after exposure to a single large dose (6.5 to 8.4 Gray) of total body radiation (TBI) derived from linear accelerator-derived photons (2 MeV, 80 cGy/minute) or Cobalt 60-derived gamma irradiation (60 cGy/min). (cdc.gov)
  • And while the stigma that surrounds addiction and recovery can make it challenging to seek help, signs of alcoholism should never be ignored. (mountainside.com)
  • Bill Wilson is widely credited with establishing the twelve-step process of recovery from alcoholism and recognized as one of the founders of the Alcoholics Anonymous movement. (12steprecovery.com)
  • In the later phases of stroke recovery, patients are encouraged to participate in secondary prevention programs for stroke. (wikipedia.org)
  • This review aimed to evaluate the efficacy and safety of VNS as a novel treatment option for post-stroke recovery. (karger.com)
  • RCTs investigating the efficacy or safety of VNS on post-stroke recovery were included. (karger.com)
  • In addition to ergogenic effects that benefit resistance training, mahuang also facilitates fat loss without loss of lean mass by helping to maintain metabolic rate and thyroid function, both very important to any long term fat loss program. (getbig.com)
  • Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. (medscape.org)
  • Leptin levels are dependent on sleep duration: relationships with sympatho-vagal balance, carbohydrate regulation, cortisol and TSH. (medscape.org)
  • HPESO hydrogel also showed fast initial partial recovery of its viscoelastic properties after being subject to a disruption mechanical shear. (usda.gov)
  • Aurora B functions to correct improper kinetochore-microtubule attachments and alert the spindle checkpoint to the presence of misaligned chromosomes. (harvard.edu)
  • Retargeting Aurora B to centromeres partially restored checkpoint signaling and Aurora B-dependent phosphorylation at centromeres and kinetochores, bypassing the need for Haspin activity. (harvard.edu)
  • Longer term follow-up data on this cohort and independent validation will be helpful to determine whether these changes persist or whether additional changes become evident with increasing time since radiation, particularly as animals begin to develop aging-related changes in immune function. (cdc.gov)
  • Compounds were then tested for efficacy in improving functional recovery and verification of cellular mechanism. (figshare.com)
  • Although the alcoholic Ss' verbal learning was unimpaired, visuospatial functioning was equally impaired initially in both alcoholic groups despite differing periods of abstinence, indicating the lack of time-dependent recovery. (usf.edu)
  • This was followed by a fast lung recovery at day 7 and 28 for both GOs. (biomedcentral.com)
  • This study will re-examine a large number of firefighters who had bronchial reactivity soon after 9/11 to determine whether those with bronchial hyper-reactivity at onset have persistent hyperactivity more than ten years later, whether they have accelerated lung function decline, and whether those treated with anti-asthma medications were more likely to show resolution of bronchial hyperactivity and/or show less rapid decline in lung function. (cdc.gov)
  • This study assesses the post-9/11 courses of lung function as influenced by bronchial hyperreactivity (BHR) a biomarker for susceptibility to asthma, and by corticosteroid treatment. (cdc.gov)
  • Bronchial hyperreactivity-abnormal sensitivity to inhaled bronchoconstrictive agents, is a biomarker for susceptibility to asthma, and may predict rapid decline in lung function. (cdc.gov)
  • We found that steroid therapy was significantly associated with recovery of lung function and that bronchial reactivity, which tended to persist or slightly worsen over the decade since 9/11, was significantly associated with worsening lung function. (cdc.gov)
  • They also demonstrate the importance of measuring lung function in advance of any lung injury, in potentially susceptible workers, for example, so as to allow accurate quantification of the injury and recovery from injury. (cdc.gov)
  • For example, smoking and inhaling substances can reduce lung function and increase vulnerability to infections. (who.int)
  • The precise mechanism of action is dependent upon dose scheduling of this drug. (aspetjournals.org)
  • Excluding 2 subjects with restrictive disease, a multiple regression model with dependent variable 'subsequent' (2002-2013) change in FEV1%, showed significant (p=.03) negative contributions from initial FEV1% change and smoking, and a positive contribution from approximated steroid dose. (cdc.gov)
  • Effects of prior radiation on production and export of new T cells by the thymus was dependent on age at the time of analysis, with evidence of interaction with radiation dose for CD8+ T cells. (cdc.gov)
  • Additionally, this discussion expands its mandate by analyzing the function and regulation of anti-cell death in plant development. (essaywriter.org)
  • These studies determined the effects of continuous phencyclidine (PCP) administration on cytochrome P 450 2C11 (CYP2C11) function, protein expression and mRNA levels. (aspetjournals.org)
  • Chapter 14 is about developing a Disaster Recovery Plan to help mitigate risk. (majortests.com)
  • These CSFs can include management support, knowledge and authority, identification of recovery time objectives or alternate location needs, and a disaster recovery budget. (majortests.com)
  • DRP Developers need to have knowledge of disaster recovery, knowledge of the organization's functions, and authority. (majortests.com)
  • Plan, Disaster, Recovery - Be Ready! (cadalyst.com)
  • Where disaster recovery tends to deal with systems and data, business continuity is focused on overall business operations. (e-janco.com)
  • The Disaster Recovery Plan (DRP) includes the BIA Business Impact Analysis Questionnaire. (e-janco.com)
  • Disaster Recovery Business Continuity Template (WORD) - comes with the latest electronic forms and is fully compliant with all mandated US, EU, and ISO requirements. (e-janco.com)
  • Acute kidney injury (AKI) is a clinical syndrome manifested by a rapid or abrupt decline in kidney function and subsequent dysregulation of the body electrolytes and volume, and abnormal retention of nitrogenous waste. (medscape.com)
  • These results indicate that TT association with SR-stacks enhances Orai1-dependent SOCE to optimize Ca 2+ dynamics and muscle contractile function during acute exercise. (elifesciences.org)
  • Other substances modify the brain with repeated use causing individuals to become dependent on the drug. (12steprecovery.com)
  • A business impact analysis (BIA) predicts the consequences of disruption of a business function and process. (e-janco.com)
  • Speaking on the occasion, Dr. P N Renjen, Senior Consultant, Neurology, Indraprastha Apollo Hospitals, New Delhi said, "The recovery of a patient from stroke is completely dependent on timely medical intervention. (apollohospitals.com)
  • An electromyogram (EMG) showed normal sensory nerve function, low amplitude on motor stimulation, mild (10%) decremental response on repetitive low frequency, and incremental response on high-frequency nerve stimulation, consistent with botulism ( 13 ). (cdc.gov)
  • We provide here the first description of ASIC function in response to defined slow pH changes. (frontiersin.org)
  • Reaffirming the principle of sovereignty of States Parties in addressing public health matters, notably pandemic prevention, preparedness, response and health systems recovery, 2. (who.int)
  • Recognizing the central role of WHO, as the directing and coordinating authority on international health work, in pandemic prevention, preparedness, response and recovery of health systems, and in convening and generating scientific evidence, and, more generally, fostering multilateral cooperation in global health governance, 6. (who.int)
  • 05). CYP2C11 function, expression and reactive PCP metabolite formation returned to normal after 20 days of PCP infusion. (aspetjournals.org)
  • Some, such as functioning alcoholics , can lead seemingly normal lives and find it easy to deny their problem drinking. (mountainside.com)
  • Though the average person can often return to normal activities within a few days following minor surgery, patients undergoing a more extensive surgical procedure can often expect a long hospital stay followed by a recovery time of weeks or months before they're able to fully function without any assistance. (interimhealthcare.com)
  • Through the subsequent 6 years, there was, on average, surprisingly little evidence of recovery. (cdc.gov)
  • These features represent a more precipitous initial course than is typical for type A or type B botulism but a more rapid recovery. (cdc.gov)
  • Around the same time, Brunnstrom also described the process of recovery, and divided the process into seven stages. (wikipedia.org)
  • This challenged the belief held at that time that no recovery would occur after one year. (wikipedia.org)
  • To this end, the impact of time-dependent P450 inhibition in this system was evaluated. (aspetjournals.org)
  • Tienilic acid selectively inhibited CYP2C9-dependent diclofenac 4′-hydroxylation activity, and erythromycin, troleandomycin, and fluoxetine inhibited CYP3A4-dependent midazolam 1′-hydroxylation in a time- and concentration-dependent manner. (aspetjournals.org)
  • Fluoxetine also inhibited CYP2C19-dependent S -mephenytoin 4′-hydroxylation in a time- and concentration-dependent manner in hepatocytes, HLMs, and recombinant CYP2C19 ( K I 0.4 μM and k inact 0.5 min -1 ). (aspetjournals.org)
  • One 10-min IPC, adenosine A1 receptor antagonist (KW-3902) also shortened the recovery time of renal blood flow (RBF) and urine flow (UF), as well as mean blood pressure (BP). (eurekamag.com)
  • Advanced renal IPC attenuated the increment of adenosine and adenine nucleotides, as well as recovery time during the 60-min reperfusion which followed the 60-min renal ischemia. (eurekamag.com)
  • A significant relativity in dog models exists between the cycles of 10-min renal IPC and the recovery time of BP, UF, and RBF during the 60-min renal reperfusion following 60-min renal ischemia, respectively. (eurekamag.com)
  • Studies have reported that fatigue can extend from workers to their partners, by limiting personal resources and time to attend to household responsibilities and social recovery 18 . (cdc.gov)
  • Ideally, non-work time allows for recovery from work. (cdc.gov)
  • Knowledge of strokes and the process of recovery after strokes has developed significantly in the late 20th century and early 21st century. (wikipedia.org)
  • Similarly, for modeling 12-residue loops in the PLOP benchmark, the average main-chain root mean square deviation of the best scored conformations by SOAP-Loop is 1.5 Å, close to the average root mean square deviation of the best sampled conformations (1.2 Å) and significantly better than that selected by Rosetta (2.1 Å), DFIRE (2.3 Å), DOPE (2.5 Å) and PLOP scoring functions (3.0 Å). (nih.gov)
  • Furthermore, we find that extracellular signal-regulated kinase (ERK)-mediated retrograde signalling is required for PCAF-dependent regenerative gene reprogramming. (nature.com)
  • He found that by four weeks, if there is some recovery of hand function, there is a 70% chance of making a full or good recovery. (wikipedia.org)
  • We found that we are able to inflict a consistent and significant lesion to the hippocampus, resulting in hippocampally-dependent behavioral deficits and a long-lasting upregulation in neurogenesis, suggesting that this process might be a critical part of hippocampal recovery. (nih.gov)
  • LO35: Write input validation loops and validation functions to check accuracy of input data. (majortests.com)
  • at room temperature and viscous liquid behavior at 55 deg C. The thermal assembly-disassembly-reassembly function of the HPESO hydrogel was completely reversible. (usda.gov)
  • The viscoelastic properties of HPESO were strongly dependent on concentration. (usda.gov)
  • This process is completely dependent on the presence of oxygen as it represents aerobic respiration inside your working muscle cells. (trainingpeaks.com)
  • If you've ever had a major surgical procedure, you know an essential part of the recovery process is to get a lot of rest and relaxation. (interimhealthcare.com)
  • Unit 9: Functions Course Objectives Covered by this Unit * CO8: Apply techniques to write functions in programs. (majortests.com)
  • As knowledge of the science of brain recovery improved, intervention strategies have evolved. (wikipedia.org)
  • We examined the survival, maturation, self-organization and integration of the graft as well as its impact on lesion-dependent motor alterations up to 6 months post-graft. (lu.se)
  • Welcome to today's hearing, ''The Impact of Economic Recovery Efforts on Corporate and Commercial Real Estate Lending. (stlouisfed.org)
  • Using relevant sources of literature, the paper delivers a systematic analysis of fascinating analogies between cell death and plant development with respect to the primary functions of cell death as stipulated in the introductory outline of the discussion. (essaywriter.org)
  • Although the RST is present postnatally in cats, nothing is known about when rubrospinal projections could support motor functions or the relation between the development of the motor functions of the rubrospinal system and the corticospinal system, the other major system for limb control. (jneurosci.org)
  • In contrast, beginning at PW5 there was delayed and age-dependent development of forelimb motor pool projections and putative rubromotoneuronal synapses. (jneurosci.org)
  • Such a sequential pattern of development implies that the two systems contribute unique motor commands, and would help explain why spontaneous recovery from injury is most often incomplete. (jneurosci.org)
  • In earlier work, we showed that World Trade Center (WTC)-exposed firefighters lost, on average, about 10% of their pre-9/11 pulmonary function, due almost entirely to the development of obstructive airways disease (OAD). (cdc.gov)
  • In addition, impaired cognition and decision-making abilities can jeopardize the development and safety of dependents. (cdc.gov)
  • If provided specialised medical attention immediately or within the first half an hour the chances of recovery improve dramatically. (apollohospitals.com)
  • Firefighters participating in rescue/recovery work at the World Trade Center site lost an average of ~10% of FEV1 in the first post-9/11 year, with little apparent recovery (on average) over the next 6 years. (cdc.gov)
  • The success of your DRP is dependent on several critical success factors. (majortests.com)
  • However, it is important to understand that the degree of success is dependent on a number of factors. (kellysearch.com)
  • Current evidence indicates that most significant recovery gains will occur within the first 12 weeks following a stroke. (wikipedia.org)
  • Thankfully, the chances of a successful SQL repair are very high with a thorough examination and the appropriate data recovery software used to identify the issues caused by the malware. (datanumen.com)
  • Our other data recovery programs include repair for Outlook, Excel and Word, among others. (datanumen.com)
  • We derive a general Bayesian framework for inferring statistically optimized atomic potentials (SOAP) in which the reference state is replaced with data-driven 'recovery' functions. (nih.gov)
  • Effects of 1-beta-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function. (aspetjournals.org)
  • These factors can be the general health and age of the patient, the condition that is to be treated, and the willingness of the patient to comply with the recovery guidelines after the procedure. (kellysearch.com)
  • This figure reports the experiments done for creating a kinetic model of ASIC1a function. (frontiersin.org)
  • The program is based on a twelve-step model of recovery and members can maintain unity of purpose by applying twelve traditions to their groups. (12steprecovery.com)
  • For docking, a near-native model is within the top 10 scoring models in 40% of the PatchDock benchmark cases, compared with 23 and 27% for the state-of-the-art ZDOCK and FireDock scoring functions, respectively. (nih.gov)