• One of the common mutations of DNA involves two adjacent thymines or cytosine, which, in presence of ultraviolet light, may form thymine dimers, causing "kinks" in the DNA molecule that inhibit normal function. (wikipedia.org)
  • The top chain is now one base longer (in this case, a molecule of thymine - "T"). The new thymine (blue box), which is now at the end of the growing chain, is now attached to cytosine by a new bond (indicated by the blue block arrow). (acsh.org)
  • Sugar molecule = deoxyribose. (jlindquist.com)
  • In it, two strands, composed of sugar (deoxyribose) and phosphate molecules, are connected by pairs of four molecules called bases, which form the steps of the staircase. (msdmanuals.com)
  • Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. (wikipedia.org)
  • In DNA, thymine (T) binds to adenine (A) via two hydrogen bonds, thereby stabilizing the nucleic acid structures. (wikipedia.org)
  • Thymine likely formed within some meteorite parent bodies, but may not have persisted within these bodies due to an oxidation reaction with hydrogen peroxide. (wikipedia.org)
  • A pair of nitrogenous bases make up the steps of the DNA ladder, whereas the perimeters of the ladder are manufactured from deoxyribose and phosphate molecules. (worksheetstemplate.com)
  • Ueber das Thymin, ein Spaltungsproduct der Nucleïnsäure" [On thymine, a cleavage product of nucleic acid]. (wikipedia.org)
  • Thymine has not been found in meteorites, which suggests the first strands of DNA had to look elsewhere to obtain this building block. (wikipedia.org)
  • Thymine was first prepared by hydrolysis of the corresponding nucleoside obtained from natural sources. (wikipedia.org)
  • The urine of six patients infected with thy − mutants contained levels of a thymine-like compound sufficient to support their growth. (microbiologyresearch.org)
  • The mutations caused by thymine deficiency appear to occur only at AT base pair sites in DNA and are often AT to GC transition mutations. (wikipedia.org)
  • Secondary mutations to a low thymine requirement may now be occurring more rapidly, thereby allowing more mutant organisms to survive. (microbiologyresearch.org)
  • The top of Figure 1 shows the single-stranded DNA template (black dotted arrow), the polymerase (gray blob), the last base that was added to the newly forming chain (cytosine, red box), and the position (red arrow) of next base which will be added to it (thymine, purple circle). (acsh.org)
  • Thymine bases are frequently oxidized to hydantoins over time after the death of an organism. (wikipedia.org)