• Deoxyribonuclease (DNase, for short) refers to a group of glycoprotein endonucleases which are enzymes that catalyze the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA. (wikipedia.org)
  • A wide variety of deoxyribonucleases are known and fall into one of two families (DNase I or DNase II), which differ in their substrate specificities, chemical mechanisms, and biological functions. (wikipedia.org)
  • The two main types of DNase found in animals are known as deoxyribonuclease I (DNase I) and deoxyribonuclease II (DNase II). (wikipedia.org)
  • Deoxyribonuclease I (DNase I) , ≥ 200. (gendepot.com)
  • DNase I (Deoxyribonuclease I ) is a dialyzed lyophilized powder from bovine pancrease that has been purified by chromatography Bovine pancreatic dexoy ribonuclease I (DNase I) is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding polynucleotides with a free hydroxyl group at the 3' position and phosphate group at the 5' position. (gendepot.com)
  • It can block ribonuclease (RNase) and deoxyribonuclease (DNase) activity. (sigmaaldrich.com)
  • This study aimed at gaining insights into the contributions of eDNA to C. albicans biofilms antifungal susceptibility by the investigation of the impact of the combined use of deoxyribonuclease I (DNase) and antifungals to treat biofilms. (who.int)
  • Bovine pancreatic deoxyribonuclease I (DNase I) is a DNA minor grove-interacting nuclease , which shows relatively low specificity. (thomassci.com)
  • Consider also performing another test like anti-DNase B (anti-deoxyribonuclease B), which, when combined with the ASO titer, can detect up to 95% of streptococcal infections compared to 80% with the ASO titer test alone. (medscape.com)
  • To determine the effect of repeated doses of aerosolized recombinant human deoxyribonuclease (rhDNase) on the development of anti-rhDNase antibodies, acute allergic reactions, and pulmonary function in patients with cystic fibrosis. (nih.gov)
  • Due to the similarity between the two enzymes and the fact that they belong to the same enzyme-sub class, similar results are expected for deoxyribonuclease. (europa.eu)
  • Suitable for measuring the viscometric assay of the deoxyribonuclease enzyme. (psl-rheotek.com)
  • It was concluded that Deoxyribonuclease, PPW38822 did not induce biologically relevant increases micronuclei in cultured human peripheral blood lymphocytes following treatment in the absence and presence of a rat liver metabolic activation system (S-9). (europa.eu)
  • During the testing of deoxyribonuclease batch PPW42035 in micronuclei in cultured human peripheral blood lymphocytes, some osmolality shifts were noted. (europa.eu)
  • It was concluded that deoxyribonuclease batch PPW42035 induced micronuclei in cultured human peripheral blood lymphocytes following treatment in the absence and presence of an induced rat liver metabolic activation system (S-9) in two independently conducted experiments. (europa.eu)
  • 2'O-Me RNA are partially resistant to a variety of ribo- and deoxyribonucleases. (eurogentec.com)
  • This graph shows the total number of publications written about "Deoxyribonuclease I" by people in this website by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publications. (umassmed.edu)
  • Deoxyribonuclease I did not affect biofilm cells susceptibility to fluconazole. (who.int)
  • Part of this material was treated with pancreatic deoxyribonuclease. (duke.edu)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Deoxyribonuclease I (DNASE1) in serum, plasma, urine, saliva, seminal plasma and other biological fluids. (tissue-cell-culture.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Deoxyribonuclease I (DNASE1) in samples from Serum, plasma, urine, saliva, seminal plasma and other biological fluids with no significant corss-reactivity with analogues from other species. (tissue-cell-culture.com)
  • Description: A sandwich ELISA kit for detection of Deoxyribonuclease I from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (tissue-cell-culture.com)
  • A wide variety of deoxyribonucleases are known, which differ in their substrate specificities, chemical mechanisms, and biological functions. (wikidoc.org)
  • Two deoxyribonuclease I gene polymorphisms and correlation between genotype and its activity in Japanese population. (cdc.gov)
  • Deoxyribonucleases are thus one type of nuclease . (wikidoc.org)
  • We report the case of a 77-year-old Caucasian man with severe dementia and behavioral disturbance secondary to Alzheimer's disease treated with memantine who began adjunct treatment with deoxyribonuclease I. Prior to initiation of deoxyribonuclease I treatment, our patient appeared to be in a stuporous state, with a Mini-Mental State Examination score of 3 and a Functional Assessment Staging Test score of 7. (medscape.com)
  • This graph shows the total number of publications written about "Deoxyribonuclease I" by people in this website by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publications. (umassmed.edu)
  • After obtaining informed consent from family members, we started administration of 120 mg of deoxyribonuclease I per day (1500 KU/mg) for treatment of severe cognitive impairment. (medscape.com)
  • Our patient began to demonstrate rapid, considerable improvement in cognitive function 2 days following initiation of deoxyribonuclease I treatment. (medscape.com)
  • Deoxyribonuclease and competence factor activities of transformable and nontransformable group H streptococci. (cornell.edu)