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  • interactions
  • Fluorescent protein labeled bacteria, live/dead staining kit will be used to visualize the interactions in the biofilm. (acta.nl)
  • However, despite substantial research into cause of these infectious oral diseases, relatively little progress has been made in understanding how community dynamics and species interactions drive disease. (springer.com)
  • Future work will continue to be directed towards understanding the molecular mechanisms of bacterial cell-cell interactions and biofilm formation. (ncl.ac.uk)
  • These new research directions made oral microbiologists truly appreciate the fact that the whole is much more than the simple sum of its parts, since the interactions between different components resulted in many new physiological functions which cannot be observed with individual components. (pubmedcentralcanada.ca)
  • vitro
  • Several in vitro oral biofilm growth systems can reliably construct oral microbiome communities in culture, yet their stability and reproducibility through time has not been well characterized. (springer.com)
  • Differences in immunological and physiological responses to stimulation with bacterial structures such as LPS, single bacterial species, and multiple bacterial species in vitro and in vivo have demonstrated that it is necessary to study polymicrobial-induced diseases with complex communities to better understand disease etiology. (springer.com)
  • In vitro , 16 oral bacterial strains were tested using agar diffusion susceptibility, minimum inhibitory and minimum bactericidal concentration tests. (frontiersin.org)
  • microbiome
  • If there is a core, then it would be possible to associate certain community compositions with disease states, which is one of the goals of the Human Microbiome Project. (wikipedia.org)
  • The shift in oral microbiome after 1 week of rinsing deserves further research. (frontiersin.org)
  • Dental plaque biofilm is part of the oral microbiome that co-evolves in symbiosis with the human host ( Marsh, 2012 ). (frontiersin.org)
  • The observed stabilisation of bacterial microflora confirms the beneficial activity of toothpaste containing EEP and TTO compared to the control group, where the lack of these substances contributed to the emergence of qualitative and quantitative changes in oral microbiome. (mdpi.com)
  • To understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. (biomedcentral.com)
  • The bacterial microbiome of the human digestive tract contributes to both health and disease. (biomedcentral.com)
  • Microbiology
  • In 1998 I started to apply my experience to the field of Oral Microbiology as a Post-Doctoral researcher in Prof. Howard Jenkinson's group at the Bristol Dental School. (ncl.ac.uk)
  • I joined Newcastle Dental School as Lecturer in Oral Microbiology in 2007 and was promoted to Senior Lecturer in 2014. (ncl.ac.uk)
  • This review uses oral microbial communities as a focal point to describe this new trend and discuss its possible impact on future studies in microbiology. (pubmedcentralcanada.ca)
  • interdental
  • Plaque control and removal can be achieved with correct daily or twice-daily tooth brushing and use of interdental aids such as dental floss and interdental brushes. (wikipedia.org)
  • In oral health, the interdental spaces are a real ecological niche for which the body has few or no alternative defenses and where the traditional daily methods for control by disrupting biofilm are not adequate. (frontiersin.org)
  • The interdental spaces are the source of many hypotheses regarding their potential associations with and/or causes of cardiovascular disease, diabetes, chronic kidney disease, degenerative disease, and depression. (frontiersin.org)
  • P. gingivalis was detected in 19% of healthy subjects and represents 0.02% of the interdental biofilm. (frontiersin.org)
  • T. forsythensis and T. denticola (0.02 and 0.04% of the interdental biofilm) were detected in 93 and 49% of healthy subjects, respectively. (frontiersin.org)
  • Of all of the parts of the human body, the interdental (ID) space is a unique place, a real ecological niche, for which the body has few or no alternative defenses and where the traditional daily methods for control by disrupting biofilm are not adequate. (frontiersin.org)
  • systemic diseases
  • The disease may be modified by and be associated with systemic diseases (e.g. diabetes mellitus, HIV infection) It can also be modified by factors other than systemic disease such as smoking and emotional stress. (wikipedia.org)
  • These data provide a critical baseline for future studies investigating local and systemic diseases affecting human health. (biomedcentral.com)
  • gingivitis
  • If not taken care of, via brushing or flossing, the plaque can turn into tartar (its hardened form) and lead to gingivitis or periodontal disease. (wikipedia.org)
  • 1965) 13 in an experimental gingivitis study on dental students who were restrained from all oral hygiene measures for a period of three weeks. (periobasics.com)
  • Symptoms may include the following: Redness or bleeding of gums while brushing teeth, using dental floss or biting into hard food (e.g. apples) (though this may occur even in gingivitis, where there is no attachment loss) Gum swelling that recurs Halitosis, or bad breath, and a persistent metallic taste in the mouth Gingival recession, resulting in apparent lengthening of teeth. (wikipedia.org)
  • To improve our understanding of the link between food and oral health, an international EU sixth framework program consortium project (NUTRIDENT, FOOD-CT-2006-36210) was granted with an overall aim to identify beverage/food constituents that are able to reduce the risk of two major dental diseases, caries and gingivitis. (hindawi.com)
  • We have then built upon this knowledge by testing such materials for a range of biological activities that are relevant to the maintenance of oral health, that is, the prevention of caries and gingivitis. (hindawi.com)
  • microbiota
  • Those that are expected to be present, and that under normal circumstances do not cause disease, are sometimes deemed normal flora or normal microbiota. (wikipedia.org)
  • Anti-plaque agents should not eradicate the oral microbiota. (frontiersin.org)
  • Additionally, research has correlated poor oral heath and the resulting ability of the oral microbiota to invade the body to affect cardiac health as well as cognitive function. (wikipedia.org)
  • periodontal destruction
  • in a well-maintained population who practises oral home care and has regular check-ups, the incidence of incipient periodontal destruction increases with age, the highest rate occurs between 50 and 60 years, and gingival recession is the predominant lesion before 40 years, while periodontal pocketing is the principal mode of destruction between 50 and 60 years of age. (wikipedia.org)
  • tissues
  • Bacterial diseases such as chronic periodontal disease evoke the host's immune responses, involving both the innate and adaptive signalling mechanisms with cell recruitment from the systemic circulation (macrophages, plasma cells, and T and B lymphocytes) that infiltrate the gingival soft tissues [ 1 ]. (hindawi.com)
  • For periodontal treatment, the full mouth disinfection approach suggests disinfection of oral soft tissues, such as tongue and tonsils concomitant to scaling and root planning since patients might benefit from treatment of these oral niches either. (springer.com)
  • salivary
  • The exact composition of the microbial population within plaque varies based on site (e.g. smooth surface, pit and fissure , interproximal), available substrate, salivary components, duration and oral hygiene practices of YOU . (everything2.com)
  • hygiene
  • There is professional agreement among dentists that smoking cessation and good oral hygiene are key to effective treatment and positive outcomes for patients. (wikipedia.org)
  • gums
  • Symptoms may include the following: Redness or bleeding of gums while brushing teeth, using dental floss or biting into hard food (e.g. apples) (though this may occur even in gingivitis, where there is no attachment loss) Gum swelling that recurs Halitosis, or bad breath, and a persistent metallic taste in the mouth Gingival recession, resulting in apparent lengthening of teeth. (wikipedia.org)
  • mechanisms
  • Collectively, these results suggest that lipid raft-mediated process is at least one of the potential mechanisms involved in fusobacterium-modulated host cell invasion by has been proposed as a possible mechanism of pathogenesis in periodontal and cardiovascular diseases [3C (paccon2016.com)
  • Oral bacteria have evolved mechanisms to sense their environment and evade or modify the host. (wikipedia.org)
  • Archives of Oral Biology
  • Demonstration of mitochondrial oestrogen receptor β and oestrogen-induced attenuation of cytochrome c oxidase subunit I expression in human periodontal ligament cells," Archives of Oral Biology , vol. 52, no. 7, pp. 669-676, 2007. (hindawi.com)
  • Archives of Oral Biology 2017;83:169-173. (hku.hk)
  • present
  • The typical initial treatment known to be effective is scaling and root planing (SRP) to mechanically debride the depths of the periodontal pocket and disrupt the biofilm present. (wikipedia.org)
  • infection
  • The disease may be modified by and be associated with systemic diseases (e.g. diabetes mellitus, HIV infection) It can also be modified by factors other than systemic disease such as smoking and emotional stress. (wikipedia.org)
  • role
  • S. mutans and other anaerobes are the initial colonisers of the tooth surface, and play a major role in the establishment of the early biofilm community. (wikipedia.org)
  • Research
  • People with high blood pressure taking medication for their condition are more likely to benefit from the therapy if they have good oral health, according to new research in the American Heart Association's journal Hypertension . (doctorkrape.com)
  • occurs
  • in a well-maintained population who practises oral home care and has regular check-ups, the incidence of incipient periodontal destruction increases with age, the highest rate occurs between 50 and 60 years, and gingival recession is the predominant lesion before 40 years, while periodontal pocketing is the principal mode of destruction between 50 and 60 years of age. (wikipedia.org)
  • potential
  • The aim of this article is to provide the dental practitioner about the potential inadvertent effects of sodium hypochlorite and its management on encountering a dental emergency. (omicsonline.org)