• vaccine
  • There is no vaccine against dengue fever yet. (kidshealth.org)
  • The findings add to the conundrum that governments face, as the vaccine prevents hospital stays in children who have antibodies to the dengue virus. (umn.edu)
  • The controversial dengue vaccine should not be used until clinicians can confirm prior dengue infection, and such a test is at least 2 years away. (umn.edu)
  • A vaccine is available for people living in some Dengue endemic countries, but is not commercially available for travellers. (iamat.org)
  • A novel vaccine for dengue fever has been approved and is commercially available in a number of countries. (wikipedia.org)
  • Recombinant domains of the E protein are used as well-defined antigens in the serological detection of antibodies directed against dengue virus and as immunogens in vaccine candidates. (wikipedia.org)
  • Dengue vaccine is a vaccine to prevent dengue fever in humans. (wikipedia.org)
  • In 2017 the manufacturer recommended that the vaccine only be used in people who have previously had a dengue infection, as outcomes may be worsened in those who have not been previously infected. (wikipedia.org)
  • The development of vaccine for dengue fever began as early as 1929, but has been hindered first by incomplete knowledge of the disease pathogenesis, and later by the need to simultaneously create a stable immunity against all four dengue serotypes. (wikipedia.org)
  • CYD-TDV, sold under the brand name Dengvaxia and made by Sanofi Pasteur , is a live attenuated tetravalent chimeric vaccine made using recombinant DNA technology by replacing the PrM (pre-membrane) and E (envelope) structural genes of the yellow fever attenuated 17D strain vaccine with those from four of the five dengue serotypes. (wikipedia.org)
  • In 2017 the manufacturer recommended that the vaccine only be used in people who have previously had a dengue infection as otherwise there was evidence it may worsen subsequent infections. (wikipedia.org)
  • In both trials vaccine reduced by about 80% the number of severe dengue cases. (wikipedia.org)
  • An analysis of both the Latin American and Asian studies at the 3rd year of follow-up showed that the efficacy of the vaccine was 65.6% in preventing hospitalization in children older than 9 years of age, but considerably greater (81.9%) for children who were seropositive (indicating previous dengue infection) at baseline. (wikipedia.org)
  • DENVax is a recombinant chimeric vaccine with DENV1, DENV3, and DENV4 components on a dengue virus type 2 (DENV2) backbone originally developed at Mahidol University in Bangkok and now funded by Inviragen and Takeda. (wikipedia.org)
  • The Philippine Department of Health (DOH), on December 1, 2017, temporarily suspends a school-based dengue vaccination program after French drug based-Dengvaxia vaccine maker Sanofi Pasteur made a statement, two days prior, that its product poses higher risks to people without prior dengue infection. (wikipedia.org)
  • Prior to that, in 2016, the Department of Health (DOH), launched the dengue vaccination in regions Central Luzon, Calabarzon and Metro Manila, where about 700,000 individuals received at least one dose of the vaccine. (wikipedia.org)
  • Hontiveros said that Sanofi should take liability for the medical expenses of those who contracted severe dengue cases after receiving doses of vaccine. (wikipedia.org)
  • Sanofi representative Thomas Triomphe "was forced to apologize" during the House hearing on the Dengvaxia dengue vaccine. (wikipedia.org)
  • Secretary Duque reminded to the public, especially parents, that "that the vaccine is not a "standalone" preventive measure against dengue. (wikipedia.org)
  • A girl named Christine Mae de Guzman from Mariveles, Bataan died of severe dengue about six months after she was given a vaccine. (wikipedia.org)
  • The victims' parents blamed the dengue vaccine for the deaths of their children. (wikipedia.org)
  • antibodies
  • Seroprevalence of dengue and chikungunya virus antibodies, French Polynesia, 2014-2015. (umn.edu)
  • Virologists say a combination test that looks simultaneously for direct evidence of the dengue virus as well as antibodies against it is far superior to exclusive antibody tests favoured by the public health authorities. (telegraphindia.com)
  • World Health Organ
  • The World Health Organization provided technical guidance along with support for provincial and territorial dengue monitoring and coordination committees. (wikipedia.org)
  • DOH Secretary Francisco Duque III said that "In the light of this new analysis, the DOH will place the dengue vaccination on hold while review and consultation is ongoing with experts, key stakeholders and the World Health Organization. (wikipedia.org)
  • anti-dengue
  • A panel of experts had also been set up to advise the government on anti-dengue measures. (wikipedia.org)
  • On December 2, 2017, the government of Makati immediately suspended its anti-dengue vaccination drive following its statement. (wikipedia.org)
  • acute dengue
  • Treatment of acute dengue is supportive and includes giving fluid either by mouth or intravenously for mild or moderate disease. (wikipedia.org)
  • virus
  • Macrophages (Mϕ) are the major source of inflammatory cytokines and aretarget cells for dengue virus (DV) replication. (biomedcentral.com)
  • The infected mosquito will then carry the dengue virus and pass it onto a healthy person when it bites him/her and causing them to fall sick. (slideshare.net)
  • Dengue fever is caused by a virus that is spread through the bite of an infected mosquito. (bphc.org)
  • There are 4 different types of dengue fever virus. (bphc.org)
  • A person is only protected against the type of dengue fever virus they have been infected with and will not gain protection from the other types of dengue fever virus. (bphc.org)
  • If you are infected with the same Dengue virus serotype you become immune to future infections. (iamat.org)
  • Dengue virus (DENV) is the cause of dengue fever. (wikipedia.org)
  • Nevertheless, scientists are finding their understanding of dengue virus may be simplistic, as rather than distinct antigenic groups there appears to be a continuum. (wikipedia.org)
  • This same study identified 47 strains of dengue virus. (wikipedia.org)
  • The specific targets are: Dengue virus Hepatitis C virus West Nile virus Yellow fever virus Discovering Dengue Drugs - Together is divided into two phases. (wikipedia.org)
  • Dengue come to Pakistan through the second hand tires which Pakistan imported from Thailand and this virus first spread in Karachi. (wikipedia.org)
  • Health Minister Khaw Boon Wan said that one of the concerns is that more Singaporeans are infected with Dengue Type 3, which is a new strain of the dengue virus. (wikipedia.org)
  • He also highlighted the importance of dengue, a related mosquito-borne virus, as a cause of neurological disease. (wikipedia.org)
  • malaria
  • Diseases such as dengue fever, hepatitis, tuberculosis, malaria and pneumonia continue to plague India due to increased resistance to drugs. (wikipedia.org)
  • epidemics
  • During dengue fever epidemics, the Pakistan army created camps in Lahore city. (wikipedia.org)
  • Comparison of prevalence of dengue maculopathy during two epidemics with differing predominant serotypes. (bmj.com)
  • The first recognized dengue epidemics occurred almost simultaneously in Asia, Africa, and North America in the 1780s, shortly after the identification and naming of the disease in 1779. (wikipedia.org)
  • outbreaks
  • The mosquito is an urban one, and dengue outbreaks in poor "third world" urban slums can be particularly deadly for young children. (everything2.com)
  • Manifestations of dengue in the eye, though rare in the past, are now more recently noted to be common in some outbreaks. (bmj.com)
  • Significant outbreaks of dengue fever tend to occur every five or six months. (wikipedia.org)
  • 2017
  • In the 2017 dengue outbreak in Peshawar larger incidents of dengue fever was reported in Peshawar by month of August. (wikipedia.org)
  • Following the statement by the dengue vaccination maker Sanofi Pasteur on December 1, 2017, DOH suspended the vaccination program based in schools due to the concern that it worsen the disease in some cases. (wikipedia.org)
  • prevention
  • Effectiveness and economic assessment of routine larviciding for prevention of chikungunya and dengue in temperate urban settings in Europe. (umn.edu)
  • A 24-hour government sponsored online service, the "Punjab Health Line Project For Dengue" provided information about the disease and its prevention. (wikipedia.org)
  • The Union health ministry has laid down a protocol, as part of the National Vector Borne Disease Control Programme, for surveillance and prevention of dengue and other mosquito-borne diseases. (telegraphindia.com)
  • He will co-ordinate with the five mayors in Singapore to reach out to the 84 advisers and the town councils, to oversee dengue prevention measures at the community level. (wikipedia.org)
  • Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control (PDF). (wikipedia.org)
  • occurs
  • Dengue occurs in urban and suburban settings with higher transmission rates happening during the rainy season. (iamat.org)
  • deaths
  • On March 20, 2008, the secretary of health of the state of Rio de Janeiro, Sérgio Côrtes, announced that 23,555 cases of dengue, including 30 deaths, had been recorded in the state in less than three months. (wikipedia.org)
  • In the 2006 dengue outbreak in India, cases of dengue fever were reported first from New Delhi in early September and by the end of September other states also started to report deaths. (wikipedia.org)
  • By 9 October 2006 more than fifty deaths were reported to dengue fever and more than 3613 patients were treated for this disease. (wikipedia.org)
  • Highest no of dengue deaths in Delhi today, Hindustan Times. (wikipedia.org)
  • cases
  • Most cases of dengue fever will go away within a couple of weeks and won't cause any long-term problems. (kidshealth.org)
  • The " Seet Quek Lim triad" of flashes of light, floaters and blurring of vision (29) may now warrant an ophthalmic consult and if not requested may be construed as negligence if eventually the patient loses vision, because dengue vision loss can be irreversible and may be seen in up to 10 percent of cases and has potential to cause bilateral irreversible visual impairment or blindness as reported. (bmj.com)
  • If it is uveitis it may recover well with steroids like some reports suggest (35) but bilateral cases like vasculitis and macular oedema (36) one may need to use newer medications and even 66 years after eye manifestations of dengue were first reported (37) ,dengue continues to blind people and greater awareness and timely referral is important even today. (bmj.com)
  • With hundreds of cases - and one death - last season, North Queensland s Dengue Action Response Team puts their strategy to the test, and we find out if it s really mozzie-proof. (abc.net.au)
  • On Saturday, the minister of state for health, Chandrima Bhattacharya, had said 64 cases of dengue had been detected in Calcutta till August 7. (telegraphindia.com)
  • Leave alone three years, the health department or the civic body does not have the exact number of dengue cases this year, said an official. (telegraphindia.com)
  • The cyclical rise and fall in numbers of dengue cases is thought to be the result of seasonal cycles interacting with a short-lived cross-immunity[clarification needed] for all four strains in people who have had dengue. (wikipedia.org)
  • Reported cases of dengue are an under-representation of all cases when accounting for subclinical cases and cases where the patient did receive medical treatment. (wikipedia.org)
  • In 2005, there were a total of 14,209 dengue fever cases and 25 people died. (wikipedia.org)
  • Some experts, such as Dr Paul Reiter, Professor of Entomology at the Pasteur Institute in France, suggested that Singapore's success in suppressing the dengue has partly contributed to this year sudden increase in dengue cases. (wikipedia.org)
  • In the 2015 dengue outbreak in Taiwan, a significant rise in the number of dengue fever cases was reported in Tainan City, Kaohsiung City, and Pingtung City. (wikipedia.org)
  • In the 2013 dengue outbreak in Singapore, a significant rise in the number of dengue fever cases was reported in Singapore. (wikipedia.org)
  • In the week of 16-22 June 2013, there was a record of 842 dengue cases in Singapore in a single week. (wikipedia.org)
  • The number of dengue cases is rising at a faster rate and is expected to surpass 1,000 infections in a week. (wikipedia.org)
  • In the fourth week of June, a total of 842 new cases were reported, bringing the total number of dengue cases to cross the 11,000 mark. (wikipedia.org)
  • The total number of Dengue cases subsequently crossed the 13,000 mark on 16 July 2013. (wikipedia.org)
  • At least 3613 confirmed cases of dengue fever were reported and over 50 people died in the outbreak. (wikipedia.org)
  • New Delhi: By early October more than 590 cases of dengue fever were reported from Delhi and over 367 from neighbouring states who had come to New Delhi for treatment. (wikipedia.org)
  • Chandigarh: 159 cases of dengue fever were reported. (wikipedia.org)
  • Accessed 9 October 2006 Chandigarh reports 159 suspected dengue cases, Daily India, Accessed 9 October 2006 "Nationwide data on outbreak, The Hindu. (wikipedia.org)
  • diseases
  • It is still early days for nowcasting and similar tools for understanding the spread of diseases like flu and dengue - we're excited to see what comes next. (google.org)
  • Dengue is one of the most important emerging vector-borne viral diseases. (biomedcentral.com)
  • Punjab
  • The secretary of the Punjab Mineral Development Corporation, Ataullah Siddiqui and Ghiasuddin, a member of the Punjab Public Service Commission died as a result of the dengue fever. (wikipedia.org)
  • After an appeal by the Government of Punjab (Pakistan) , private hospitals agreed to provide free treatment to dengue patients. (wikipedia.org)
  • url= http://tribune.com.pk/story/251381/dengue-alert-punjab-govt-closes-schools-for-10-days/ "Dengue alert: Punjab govt closes schools for 10 days. (wikipedia.org)
  • Express Tribune.com "No end to Dengue fever in Punjab. (wikipedia.org)
  • Holtzman
  • Dengue Fever gained notoriety through shows in L.A. and San Francisco, where, Holtzman says, some members of the audience were already familiar with '60s Cambodian pop through the mysterious Cambodia Rocks compilation album released at about the same time. (metroactive.com)
  • vaccination
  • The initial protocol did not require baseline blood samples prior to vaccination in order to establish an understanding of increased risk of severe dengue in participants who had not been previously exposed. (wikipedia.org)
  • 14,209
  • As official data showed, more than 13,000 people were infected with dengue as of mid-July in 2013, fast nearing the total 14,209 infections in 2005 dengue outbreak, the worst year on record. (wikipedia.org)
  • Southeast Asia
  • Dengue was once prevalent only in Southeast Asia , but as the mosquito vectors have spread, so has the disease. (everything2.com)
  • Through the Arts Envoy Program of the Bureau of Educational and Cultural Affairs, the U.S. Department of State is pleased to bring the rock band Dengue Fever back to Southeast Asia," said Acting Deputy Assistant Secretary of State for Public Diplomacy in the Bureau of East Asian and Pacific Affairs, Thomas Hodges. (concordmusicgroup.com)