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  • nerves
  • If the nerves lost to denervation are part of the neuronal communication to a specific function in the body then altered or a loss of physiological functioning can occur. (wikipedia.org)
  • reductions
  • In recent years, concerns have been raised that the magnitude of the blood pressure reductions seen in renal denervation studies without control groups would not hold up in controlled trials, and those concerns now appear to be well founded. (medpagetoday.com)
  • The SPYRAL HTN-ON MED and RADIANCE-HTN SOLO trials tested two different devices in two different patient populations, but results from both studies linked renal denervation with significant reductions in BP on several assessments with little to no safety concerns. (healio.com)
  • occur
  • Cardiac noradrenergic denervation and attenuated baroreflex-cardiovagal function occur in de novo PD, but whether these abnormalities can precede PD has been unknown. (biomedsearch.com)
  • The results lead us to hypothesize that cardiac noradrenergic denervation and decreased baroreflex-cardiovagal function may occur early in the pathogenesis of PD. (biomedsearch.com)
  • symptoms
  • Denervation processes have a strong association with the symptoms seen in post-polio syndrome. (wikipedia.org)
  • Following an acute polio infection diagnosis symptoms such as fatiguability, general weakness and pain are believed to be correlated to muscle denervation. (wikipedia.org)
  • blood pressure
  • In our case, we present a 39-year-old patient with high blood pressure (BP) of 10-year evolution, left ventricular hypertrophy, and left putaminal hypertensive intracranial hemorrhage, which occurred one year before denervation. (ahajournals.org)
  • However, renal denervation is used less frequently in recent years due to new evidence suggesting that blood pressure is not significantly reduced after the procedure and there are even recommendations against using the procedure since there has been little proof to show that renal denervation leads to reduced blood pressure. (wikipedia.org)
  • muscle
  • The motor unit areas soon increase to a point where reinnervation is no longer possible causing an uncompensated denervation of motor units which leads to muscle atrophy and loss of muscular strength. (wikipedia.org)
  • In regard to skeletal muscle denervation there are two distinct diagnoses: entrapment and compressive neuropathies or non-entrapment neuropathies. (wikipedia.org)
  • Following denervation, muscular atrophy and degeneration occurs within affected skeletal muscle tissue. (wikipedia.org)
  • Denervation affects the muscle activation process that is brought on by the development and propagation of an action potential and the ensuing release of calcium. (wikipedia.org)
  • different
  • Together, [the SPYRAL HTN-ON MED and OFF MED and RADIANCE-HTN SOLO] trials suggest that a renal denervation class effect might apply, in that performing renal denervation with different intravascular techniques yields the same results. (healio.com)
  • Typically, numerous ablations are applied at a different longitudinal and rotational positions to ensure maximal denervation. (wikipedia.org)
  • trial
  • Aronow, however, said that it is premature to conclude whether any other renal denervation systems would have fared better in the trial, which "set the bar high. (medpagetoday.com)
  • Explanations offered for this mismatch include renal denervation obliterating the white coat response, thereby disproportionately reducing clinic pressures, or inadvertent bias arising from the unblinded design and lack of sham control procedure in almost all renal denervation trial designs to date. (wikipedia.org)