Demonstrates chemotherapeutic drug screening assays antitumor. Medical search. Frequent questions

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Anatomy18

Cell Line, Tumor Tumor Cells, Cultured KB Cells Cell Line HCT116 Cells Neoplastic Stem Cells HT29 Cells HL-60 Cells K562 Cells Hep G2 Cells Mitochondria Cells, Cultured HeLa Cells MCF-7 Cells Spheroids, Cellular T-Lymphocytes, Cytotoxic CD8-Positive T-Lymphocytes Jurkat Cells

Organisms6

Mice, Nude Mice, Inbred BALB C Mice, SCID Mice, Inbred C57BL Adenoviridae Oncolytic Viruses

Diseases39

Neoplasms Neoplasms, Experimental Breast Neoplasms Melanoma, Experimental Lung Neoplasms Colonic Neoplasms Leukemia P388 Melanoma Sarcoma 180 Ovarian Neoplasms Leukemia L1210 Adenocarcinoma Liver Neoplasms Fibrosarcoma Neuroblastoma Prostatic Neoplasms Carcinoma, Hepatocellular Mammary Neoplasms, Experimental Brain Neoplasms Pancreatic Neoplasms Osteosarcoma Neovascularization, Pathologic Neoplasm Metastasis Glioblastoma Glioma Disease Models, Animal Lymphoma Carcinoma Carcinoma, Lewis Lung Bone Neoplasms Leukemia Sarcoma, Experimental Colorectal Neoplasms Carcinoma, Squamous Cell Multiple Myeloma Carcinoma, Non-Small-Cell Lung Necrosis Skin Neoplasms Cell Transformation, Neoplastic

Chemicals and Drugs113

Antineoplastic Agents Doxorubicin Antibiotics, Antineoplastic Cisplatin Paclitaxel Antineoplastic Agents, Phytogenic Etoposide P-Glycoprotein Fluorouracil Antineoplastic Agents, Alkylating Antimetabolites, Antineoplastic Proto-Oncogene Proteins c-bcl-2 Tumor Suppressor Protein p53 Daunorubicin Camptothecin Caspases Vinblastine Deoxycytidine Vincristine RNA, Small Interfering Mitomycin Apoptosis Regulatory Proteins Caspase 3 Cyclophosphamide TNF-Related Apoptosis-Inducing Ligand Neoplasm Proteins Drug Carriers Multidrug Resistance-Associated Proteins bcl-X Protein Enzyme Inhibitors Bleomycin Mitoxantrone Dacarbazine Taxoids Prodrugs Antibodies, Monoclonal Carmustine Receptors, TNF-Related Apoptosis-Inducing Ligand Teniposide Methotrexate Organoplatinum Compounds bcl-2-Associated X Protein Angiogenesis Inhibitors Cancer Vaccines Inhibitor of Apoptosis Proteins ATP-Binding Cassette Transporters RNA, Messenger Fenretinide Pyrazines Melphalan Cytarabine Boronic Acids Proto-Oncogene Proteins c-akt Antigens, CD95 Nanoconjugates Protein Kinase Inhibitors Topoisomerase II Inhibitors Proto-Oncogene Proteins DNA, Neoplasm Dactinomycin Membrane Glycoproteins Radiation-Sensitizing Agents Poly(ADP-ribose) Polymerases Chlorambucil Organoselenium Compounds Piperazines Bridged Compounds Carboplatin Caspase 8 Plant Extracts Quinazolines Caspase 9 P-Glycoproteins Recombinant Proteins Imidazoles Rhodamine 123 Tumor Necrosis Factor-alpha Protein-Serine-Threonine Kinases DNA-Binding Proteins Caspase 7 Antigens, Neoplasm Fas Ligand Protein NF-kappa B Flavonoids DNA Myeloid Cell Leukemia Sequence 1 Protein Sulfonamides Enediynes Pyrimidines Ceramides Histone Deacetylase Inhibitors Nuclear Proteins Cyclin-Dependent Kinase Inhibitor p21 X-Linked Inhibitor of Apoptosis Protein Reactive Oxygen Species Glutathione TOR Serine-Threonine Kinases STAT3 Transcription Factor Intracellular Signaling Peptides and Proteins Receptor, Epidermal Growth Factor Cytochromes c Cell Cycle Proteins Proto-Oncogene Proteins c-mdm2 Carrier Proteins Pyridines Tubulin Modulators Polyethylene Glycols Topoisomerase I Inhibitors Indoles Tumor Suppressor Proteins Benzamides Immunotoxins Verapamil

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Drug Screening Assays, Antitumor Xenograft Model Antitumor Assays Neoplasm Transplantation Neoplasms, Experimental Antineoplastic Combined Chemotherapy Protocols Inhibitory Concentration 50 Drug Delivery Systems Melanoma, Experimental Transplantation, Heterologous Blotting, Western Flow Cytometry Transfection Drug Carriers Immunotherapy Tumor Burden Combined Modality Therapy Drug Evaluation, Preclinical Genetic Therapy Electrochemotherapy Mammary Neoplasms, Experimental Tumor Stem Cell Assay Reverse Transcriptase Polymerase Chain Reaction Nanoconjugates Drug Administration Schedule Models, Biological Treatment Outcome Immunohistochemistry Disease Models, Animal Oncolytic Virotherapy Immunotherapy, Adoptive Injections, Intralesional Immunoblotting Sarcoma, Experimental Gene Knockdown Techniques In Situ Nick-End Labeling Clinical Trials as Topic Colony-Forming Units Assay

Phenomena and Processes45

Drug Resistance, Neoplasm Apoptosis Drug Synergism Cell Survival Drug Resistance, Multiple Cell Proliferation Dose-Response Relationship, Drug Inhibitory Concentration 50 Gene Expression Regulation, Neoplastic Cell Cycle DNA Damage Drug Resistance Cell Division Signal Transduction Cell Death Transfection Time Factors Down-Regulation Enzyme Activation Up-Regulation Cell Growth Processes RNA Interference DNA Fragmentation Phosphorylation Genetic Vectors Gene Expression DNA Repair Gene Silencing Genes, MDR Tissue Distribution Protein Binding Mutation Structure-Activity Relationship Cytotoxicity, Immunologic G2 Phase Membrane Potential, Mitochondrial Molecular Structure Base Sequence Autophagy Kinetics Necrosis Genes, p53 Cytoprotection Radiation Tolerance Cell Movement

Disciplines and Occupations2

Nanomedicine Immunohistochemistry

Technology, Industry, Agriculture4

Nanomedicine Nanoconjugates Nanoparticles Polyethylene Glycols

Information Science2

Molecular Sequence Data Base Sequence

Health Care2

Treatment Outcome Clinical Trials as Topic

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science Health Care

Antineoplastic Agents Cell Line, Tumor Doxorubicin Drug Screening Assays, Antitumor Drug Resistance, Neoplasm Antibiotics, Antineoplastic Apoptosis Xenograft Model Antitumor Assays Cisplatin Drug Synergism Tumor Cells, Cultured Neoplasms Mice, Nude Paclitaxel Cell Survival Antineoplastic Agents, Phytogenic Drug Resistance, Multiple Etoposide P-Glycoprotein Neoplasm Transplantation Cell Proliferation Fluorouracil Antineoplastic Agents, Alkylating Dose-Response Relationship, Drug Neoplasms, Experimental Antimetabolites, Antineoplastic Antineoplastic Combined Chemotherapy Protocols Inhibitory Concentration 50 Drug Delivery Systems Proto-Oncogene Proteins c-bcl-2 Breast Neoplasms Mice, Inbred BALB C Tumor Suppressor Protein p53 Gene Expression Regulation, Neoplastic Cell Cycle Daunorubicin Mice, SCID Camptothecin Melanoma, Experimental Caspases Lung Neoplasms DNA Damage Colonic Neoplasms Vinblastine Leukemia P388 Deoxycytidine Drug Resistance Vincristine Transplantation, Heterologous RNA, Small Interfering Cell Division Blotting, Western Mitomycin Apoptosis Regulatory Proteins Caspase 3 Flow Cytometry Cyclophosphamide Signal Transduction TNF-Related Apoptosis-Inducing Ligand Cell Death Transfection Neoplasm Proteins Drug Carriers Multidrug Resistance-Associated Proteins bcl-X Protein Mice, Inbred C57BL Immunotherapy Melanoma Enzyme Inhibitors Tumor Burden Sarcoma 180 Ovarian Neoplasms Time Factors Bleomycin Mitoxantrone Dacarbazine Taxoids Leukemia L1210 Combined Modality Therapy Prodrugs Drug Evaluation, Preclinical Adenocarcinoma Antibodies, Monoclonal Carmustine Receptors, TNF-Related Apoptosis-Inducing Ligand Teniposide Nanomedicine Liver Neoplasms Fibrosarcoma Down-Regulation KB Cells Methotrexate Organoplatinum Compounds bcl-2-Associated X Protein Neuroblastoma Cell Line Angiogenesis Inhibitors Genetic Therapy Enzyme Activation Up-Regulation

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