• RESULTS: Among the CDC samples, antibodies against C6 and/or pepC10 were detected in all seropositive Lyme patients (8/8), but not in sera from seronegative patients or healthy controls (0/24). (bvsalud.org)
  • The initial sign of about 80% of Lyme infections is an erythema migrans (EM) rash at the site of a tick bite, often near skin folds such as the armpit, groin, or back of the knee, on the trunk, under clothing straps, or in children's hair, ears, or neck. (wikipedia.org)
  • Filaments can be white, black, or brightly colored.2-6 Fur thermore, MD patients exhibit a variety of manifestations that resemble symptoms of Lyme disease (LD), such as fatigue, joint pain, and neuropathy.2-6 A study found that 98% of MD subjects had positive LD serology and/or a tickborne disease diagnosis,5 confirming the clinical association between MD and spirochetal infection. (allaboutheaven.org)
  • Chronic symptoms following treatment are known as "post-treatment Lyme disease syndrome" (PTLDS). (wikipedia.org)
  • Lyme disease can affect several body systems and produce a broad range of symptoms. (wikipedia.org)
  • Not everyone with Lyme disease has all of the symptoms and many of the symptoms are not specific to Lyme disease, but can occur with other diseases, as well. (wikipedia.org)
  • Lyme symptoms most often occur from May to September in the Northern Hemisphere because the nymphal stage of the tick is responsible for most cases. (wikipedia.org)
  • Signs and symptoms of Lyme disease vary by disease stage. (medscape.com)
  • This review focuses specifically on infection with Chlamydophila (Chlamydia) pneumoniae in LOAD and how this infection may function as a 'trigger or initiator' in the pathogenesis of this disease. (semcs.net)
  • As of 2023[update] clinical trials of proposed human vaccines for Lyme disease were being carried out, but no vaccine was available. (wikipedia.org)
  • DISCUSSION: MENSA-based immunoassays present a promising complement to serum immunoassays for diagnosis and tracking therapeutic success in Lyme infections. (bvsalud.org)
  • Alzheimer and a number of other neurodegenerative diseases are characterized by the presence of reactive microglia and reactive astrocytes in association with the lesions. (semcs.net)
  • Antibiotic selection, route of administration, and duration of therapy for Lyme disease are guided by the patient's clinical manifestations and stage of disease, as well as the presence of any concomitant medical conditions or allergies. (medscape.com)
  • Therapy for Lyme disease includes antibiotics that target the Bbu ribosome. (bvsalud.org)
  • Lyme carditis may be treated with either oral or parenteral antibiotic therapy for 14 days (range, 14-21 days). (medscape.com)
  • Lyme disease is the most common disease spread by ticks in the Northern Hemisphere. (wikipedia.org)
  • The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease. (semcs.net)
  • Blood tests are often falsely negative in the early stages of the disease. (wikipedia.org)
  • In combination, the serum and MENSA tests identified 10/12 early Lyme patients. (bvsalud.org)
  • Sporadic, late-onset Alzheimer's disease (LOAD) is a non-familial, progressive neurodegenerative disease that is now the most common and severe form of dementia in the elderly. (semcs.net)
  • Then we examined serum and MENSA samples from 36 uninfected Control subjects and 12 Newly Diagnosed Lyme Disease Patients. (bvsalud.org)
  • In patients with late disease, the typical physical finding is arthritis. (medscape.com)
  • Since there is no reason to perform a titer without a confirmatory test if positive, Lyme titers should always be ordered with a reflex confirmatory test. (medscape.com)
  • PTLDS is different from chronic Lyme disease, a term no longer supported by scientists and used in different ways by different groups. (wikipedia.org)