ColobomaDown SyndromeSyndromeCostello SyndromePrurigoAbnormalities, MultipleMicrophthalmosChromosomes, Human, Pair 22Gene DeletionAnophthalmosGenetic Diseases, InbornChoanal AtresiaDevelopmental DisabilitiesSequence DeletionChromosome DisordersPedigreeHeart Defects, CongenitalInfant, NewbornFetal DiseasesBirth WeightChromosome DeletionMutationPregnancyChromosome AberrationsEye AbnormalitiesHypertelorismPupil DisordersPremature BirthIrisPAX2 Transcription FactorPosterior Eye SegmentBirth RateInfant, Low Birth WeightMetabolic Syndrome XFundus OculiChoroidMolecular Sequence DataPhenotypeBase SequenceCHARGE SyndromeEye