Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2.1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. (wikipedia.org)
The specific activity of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in normally cultured HD fibroblasts was not different from that in control and escapee fibroblasts. (duke.edu)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a cellular metabolic protein, was found to colocalize with viral RNA-dependent RNA polymerase (NS5) in JEV-infected cells. (biomedcentral.com)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a glycolytic enzyme that converts glyceraldehyde -3- phosphate (G3P) to 1,3-bisphosphoglycerate and produces NADH , is a major prospective solution for the cofactor imbalance issue. (bvsalud.org)
GAPDH (glyceraldehyde-3-phosphate dehydrogenase) is known as a major target protein in oxidative stresses and becomes thiolated in its active site. (elsevierpure.com)
Malate dehydrogenase1
Light activation: Chloroplastic glyceraldehyde-3-phosphate dehydrogenase and malate dehydrogenase. (uic.edu)
Phosphate10
The first reaction is the oxidation of glyceraldehyde 3-phosphate (G3P) at the position-1 (in the diagram it is shown as the 4th carbon from glycolysis), in which an aldehyde is converted into a carboxylic acid (ΔG°'=-50 kJ/mol (−12kcal/mol)) and NAD+ is simultaneously reduced endergonically to NADH. (wikipedia.org)
Crystalline lobster-muscle glyceraldehyde-3-posphate dehydrogenase (d-glyceraldehyde-3-phosphate: NAD + oxidoreductase (phosphorylating), EC 1.2.1.12) possesses 7.3 ± 0.3 cysteine residues per mole of enzyme (140 000 g), i.e. approx. (mssm.edu)
The reaction of 5,5' dithiobis(2 nitrobenzoic acid) (DTNB) with rabbit muscle glyceraldehyde 3 phosphate dehydrogenase [d glyceraldehyde 3 phosphate: NAD + oxidoreductase (phosphorylating), EC 1.2.1.12] consists of an initial burst of reaction over several minutes, corresponding to 2 thiols/subunit, followed by a further slow reaction of the 2 remaining groups. (edu.au)
Structure-Guided Protein Engineering of Glyceraldehyde-3-phosphate Dehydrogenase from Corynebacterium glutamicum for Dual NAD/NADP Cofactor Specificity. (bvsalud.org)
The enzyme activity of glyceraldehyde-3-phosphate dehydrogenase (GADPH), neuron specific enolase (NSE), succinate dehydrogenase (SDH), and lactate dehydrogenase (LDH), has been examined in saline-perfused, desheathed and denervated peroneal (P) and tibial (T) nerves from cats treated with acrylamide (15 mg/kg/day, s.c.) or vehicle for 15 days. (cdc.gov)
Mockrin SC, Byers LD, Koshland DE Jr. Subunit interactions in yeast glyceraldehyde-3-phosphate dehydrogenase. (medscape.com)
Alcohol2
As a proof of principle, we applied this technique to yeast alcohol dehydrogenase-1 exposed in vitro to H 2 O 2 and also in vivo to the complex proteome of the Gram-negative bacterium Bacillus subtilis . (hindawi.com)
U. Ryde, L. Hemmingsen (1997) "The active-site metal coordination geometry of cadmium-substituted alcohol dehydrogenase. (lu.se)
Specific1
In contrast, only small changes occurred in the specific activity of lipoamide dehydrogenase (LADH) over the same time period, and the values were not significantly different among the three groups at any time point. (duke.edu)
Enzyme6
hGAPDS (human sperm-specific glyceraldehyde-3-phosphate dehydrogenase) is a glycolytic enzyme essential for the survival of spermatozoa, and constitutes a potential target for non-hormonal contraception. (ox.ac.uk)
Which is the coenzyme for enzyme glyceraldehyde-3- phosphate dehydrogenase? (somperi.com)
Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily. (genome.jp)
The enzyme activity of glyceraldehyde-3-phosphate dehydrogenase (GADPH), neuron specific enolase (NSE), succinate dehydrogenase (SDH), and lactate dehydrogenase (LDH), has been examined in saline-perfused, desheathed and denervated peroneal (P) and tibial (T) nerves from cats treated with acrylamide (15 mg/kg/day, s.c.) or vehicle for 15 days. (cdc.gov)