Protein oxidationThiobarbituric acid reactOxidationAntioxidantsReactiveOxidativeHepaticMalondialdehydeSerumMetabolismEnzymesMembranesFerroptosisProteinsHydrogenSuperoxideEnzyme activitiesInflammationWithstandDamageSignificantlyPeroxidesVivoIncreasesCellsMiceFreeProcessTissueStressSignificantProductionCellProtectionType
Protein oxidation2
- The total antioxidant capacity, measured through the ferric reducing ability of plasma (FRAP, µmol/equivalent FeSO4) and oxygen radical absorbance capacity (ORAC, plasma trolox equivalents), lipid peroxidation, as serum levels of the thiobarbituric acid reactive substances (TBARs, µmol MDA) and the degree of protein oxidation, as advanced Oxidation Protein Products (AOPP, µmol/g protein), were measured. (ecco-ibd.eu)
- The peroxidation of lipids (16, 17), protein oxidation, and the formation of peroxinitrites frequently occur after liver ischemia and reperfusion. (ectrx.org)
Thiobarbituric acid react1
- Highly elevated contents of thiobarbituric acid reactive substances reflected extensive lipid peroxidation processes throughout the experiment. (nih.gov)
Oxidation1
Antioxidants2
- Bilberry and chokeberry fruits are rich sources of polyphenols which may act as antioxidants and prevent lipid peroxidation. (biomedcentral.com)
- The authors conclude that PAT is toxic to cardiac myocytes and is capable of inducing a state of oxidative stress, and that antioxidants and thiol containing compounds confer a degree of protection to cells. (cdc.gov)
Reactive7
- Reactive oxygen species degrade polyunsaturated lipids, forming malondialdehyde. (wikipedia.org)
- Ferroptosis-inducing factors can directly or indirectly affect glutathione peroxidase through different pathways, resulting in a decrease in antioxidant capacity and accumulation of lipid reactive oxygen species (ROS) in cells, ultimately leading to oxidative cell death. (nature.com)
- In 2012, Dixon 1 first proposed the concept of ferroptosis, an iron-dependent, non-apoptotic mode of cell death characterized by the accumulation of lipid reactive oxygen species (ROS). (nature.com)
- say their results suggest that 'CO 2 enrichment could reduce oxidative stress of reactive oxygen species to P. subcordiformis , and reduce the lipid peroxidation damage of UV-B to P. subcordiformis . (mitosyfraudes.org)
- Objectives To translocation (externalization) of phosphatidylserine lead at least the five negative effects observed during cells cryopreservation: hypoxia, increasing of intracellular Ca2+, osmotic disruption of cellular membranes, generation of reactive oxygen species (ROS) and lipid peroxidation. (uni-koeln.de)
- Ischemia-reperfusion (I/R) in the intestines is an inflammatory condition which activates leukocytes and reactive oxygen species (ROS) and leads to lipid peroxidation and DNA damage. (biomedcentral.com)
- All reactive oxygen species respond in varying degrees at the initiation of reperfusion. (ectrx.org)
Oxidative4
- Acrolein, a byproduct of lipid peroxidation, can damage critical biomolecules, deplete endogenous antioxidant defenses, and cause mitochondrial dysfunction, which catalyzes and perpetuates oxidative stress. (purdue.edu)
- PB260 clone was used to analyze the responses of leaves chilled at 10A degrees C during 96 h, as well as their recovery at 28A degrees C. Some key parameters were used to evaluate photosynthetic apparatus functioning, membrane damage (electrolyte leakage) and oxidative stress. (sirtsignaling.com)
- These observations support the hypothesis that during hepatocarcinogenesis the loss of superoxide dismutase causes an oxidative stress that increases cellular membrane lipid peroxidation, as a consequence of which the cell responds by synthesizing more saturated fatty acids that permanently modify cell membrane structure and properties. (unicatt.it)
- lipofuscin lipid peroxidation (oxidative stress) can happen on the skin. (thegoldensecrets.com)
Hepatic2
- Following hepatic I/R, the levels of hepatic lipid peroxidation and serum alanine aminotransferase increased, while the ratio of hepatic glutathione (GSH):oxidized GSH was reduced, which was effectively attenuated by pretreatment with GP. (spandidos-publications.com)
- This study was undertaken to determine the influences of various doses of peppermint oil on the hepatic en-zymes, alanine transaminase, apartate tranaminase, alkaline phosphotase and gamma glutamyl transferase and the level of malondialdehyde in the serum of mice with and without immobility stress. (openbiochemistryjournal.com)
Malondialdehyde4
- Malondialdehyde is easily deprotonated to give the sodium salt of the enolate (m.p. 245 °C). Malondialdehyde results from lipid peroxidation of polyunsaturated fatty acids. (wikipedia.org)
- The degree of lipid peroxidation can be estimated by the amount of malondialdehyde in tissues. (wikipedia.org)
- Peroxide and malondialdehyde levels are often increased by freezing and thawing stress suggesting peroxidation of lipids [ 2 ] that result in structural and functional membrane and membrane protein changes [ 3 ]. (biomedcentral.com)
- Malondialdehyde (MDA) was used as indicator of lipid peroxidation and was measured by a calorimetric assay, lactobacilli were cultured on Rogosa agar plates and Enterobacteriaceae on VRBG agar plates, anthocyanins and phenolic acids were analysed by HPLC-DAD-ESI-MSn. (biomedcentral.com)
Serum2
- After 48 hours (hr), cultures were subjected to lipid peroxidation and cytotoxicity analyses and then washed with a salt solution and exposed to 2 milliliter aliquots of PAT in serum free M199 media for 4hr. (cdc.gov)
- Omega-3 fatty acids had no significant effect on serum lipid levels, ApoA-I, glucose, insulin and HbA1c. (who.int)
Metabolism1
- Lipid peroxidation and metabolism of nitric oxide in patients with chronic kidney disease in dynamics of treatment. (kiev.ua)
Enzymes1
- In particular, we studied the effect of varying levels of salinity, herbicide, water pH, types of predators, and temperature in spadefoot toad larvae (Pelobates cultripes) evaluating their changes in corticosterone level, metabolic rate, activity of various antioxidant enzymes, lipid peroxidation, and immune state. (upo.es)
Membranes1
- Superoxide dismutase depletion and lipid peroxidation in rat liver microsomal membranes: correlation with liver carcinogenesis. (unicatt.it)
Ferroptosis2
- Is iron necessary to promote the production of lipid peroxides, or can other substances take the place of iron in ferroptosis? (nature.com)
- Galectin-1 regulated ferroptosis by inhibiting excessive lipid peroxidation, protecting sorafenib-resistant HCC cells from sorafenib-mediated ferroptosis. (aging-us.com)
Proteins2
- Different influence of CSP 310-like proteins on mitochondrial energetic activity and lipid peroxidation presumably depend on the various subunit combinations in their composition. (biomedcentral.com)
- Lezhenko HO, Pashkova OE, Kamenschyk AV. State of activity of peroxidation of proteins in children and patients with diabetes mellitus in dynamics of disease. (kiev.ua)
Hydrogen2
- They also report that elevated UV-B significan-tly increased the production of the toxic superoxide anion and hydrogen peroxide, as well as malo-nyldialdehyde, which is an end product of lipid peroxidation, whereas elevated CO 2 did just the opposite. (mitosyfraudes.org)
- It is reported that 0.5~mol/L of idebenone can significantly reduce the degree of apoptosis induced by diethyl maleate and hydrogen peroxide, thereby inhibiting the occurrence of inflammation and improving tissue repairing ability. (inopha.net)
Superoxide1
- The essential Ca2+ mediated process(es) in ECO-induced myopathy was thought to be the generation of superoxide and superoxide-derived free radicals and/or lipid peroxidation. (aston.ac.uk)
Enzyme activities1
- The effects of chronic ethanol intoxication on the open-field behavior, on antioxidant enzyme activities, and the degree of lipid peroxidation were investigated. (nih.gov)
Inflammation1
- Cerebral ischemia-reperfusion (IR) triggers lipid peroxidation and inflammation, which exacerbate injury. (biomedcentral.com)
Withstand1
- Predictive tests evaluate the ability of a lipid to withstand peroxidation when exposed to standardised, accelerated conditions to induce peroxidation. (alemakoudijs.com)
Damage2
- DNA damage caused by exposure of pBR322 to Cr(VI)-UV is markedly inhibited by both extracts in varying degrees. (vit.ac.in)
- Apart from setting up your degree of damage, extra exploration of cornael limbal base mobile destruction after compound direct exposure could be suitable to find out reversibility or perhaps irreversibility associated with vision effects. (bace-signal.com)
Significantly2
- Feeding peroxidised lipids significantly reduces growth rate, feed intake and gain efficiency (Animal Feed and Technology 231 (2017). (alemakoudijs.com)
- The mRNA appearance degrees of and by NP cells had been significantly greater than those by AF cells (comparative appearance in the NP (vs. AF): 2.77? (idplink.net)
Peroxides1
- 20mol/L), a-tocopherol (100rtmol/L) and glutathione (50tzmol/L). It can effectively inhibit the formation of lipid peroxides. (inopha.net)
Vivo1
- However, the degree and method of Quercetin absorption in vivo has yet to be absolutely determined. (biomedjournal.com)
Increases1
- Conclusions Long time (24 h) cooling of ovarian tissue to 5 degrees C before cryopreservation decreased translocation of phosphatidylserine that evidences about increases the viability of the cells in the tissue after thawing. (uni-koeln.de)
Cells5
- Long chain fatty acids (C16-C18) must be transformed by muscle and lipid cells into a chylomicron remnant before they can be synthesised by the liver (Fig. 1). (alemakoudijs.com)
- Detectable degree of mRNA appearance of had been clearly determined in both AF and NP cells (Fig.?2). (idplink.net)
- The mRNA appearance degrees of by AF cells and the ones of by both AF and NP cells had been considerably upregulated by excitement of rhRANKL with rhIL-1 (1.0?ng/mL). (idplink.net)
- Equivalent, however, not significant developments had been also determined in the appearance degree of by both NP and AF cells, which of by NP cells: *477.75? (idplink.net)
- The thyroid is derived both embryoge- protects the cells against lipid peroxidation. (who.int)
Mice1
- Group 4 pieces (n=30) were frozen after 24 h pre-cooling to 5 degrees C, thawed, transplanted to SCID mice and then, after 45 d their quality was analyzed. (uni-koeln.de)
Free1
- The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. (biomedcentral.com)
Process1
- Some previous data do not support the liter- process in the determination of morbidity ature suggesting adverse effects of omega-3 and mortality from coronary heart disease fatty acids on lipid peroxidation [ 2,21,35 ]. (who.int)
Tissue1
- The aim of this study was to test the intensiveness of the phosphatidylserine translocation immediately after thawing and after 45 d xenografting of human ovarian tissue, which was either frozen just after operative removal from patient or cooled before cryopreservation to 5 degrees C for 24 h and then frozen. (uni-koeln.de)
Stress1
- The study of an influence of infiltration by different plant uncoupling system activators (pyruvate, which activates AOX, and linoleic acid which is a substrate and activator for PUMP and CSP 310) showed that all of these decreased lipid peroxidation during cold stress. (biomedcentral.com)
Significant1
- Similarly, in a study of mature holm and white oak trees that had been growing near natural CO 2 springs in central Italy for 30 to 50 years, Schwanze and Polle (1998) found that they exhibited significant reductions in their amounts of lipid peroxidation. (mitosyfraudes.org)
Production2
- The degree of anemia and hypoxia required to stimulate EPO production is far greater for the fetal liver than for the fetal kidney. (medscape.com)
- The lipid analysis of commercial lamb meat, from the two main Moroccan production areas Middle Atlas and highlands of eastern Morocco, was conducted. (copernicus.org)
Cell1
- Nutritional deficiencies of iron, vitamin E, vitamin B-12, and folate may exaggerate the degree of anemia, as may blood loss and/or a reduced red cell life span. (medscape.com)
Protection1
- Bilberry alone and in combination with L. plantarum HEAL19 exerts a better protection against lipid peroxidation than chokeberry. (biomedcentral.com)
Type1
- De plus, un ensemble des composés contenant des vitamines, sels minéraux, ferments lactiques et oméga 3 et 6 ainsi qu'une alimentation de type anti-inflammatoire et les aliments pauvres en glucides fermentés cibles auraient également une influence positive sur les symptômes. (bvsalud.org)