• Audiologists and speech-language pathologists (SLP) are important members of interprofessional teams that treat individuals with dementia and can provide vital information about cognitive-communication, language, and feeding/eating/swallowing skills that can contribute to appropriate diagnosis. (asha.org)
  • Cognitive changes caused by dementia may impact communication and may cause challenging behaviors (e.g., paranoia, hallucinations, and repetitiousness) and other responsive behaviors (atypical behaviors in response to stimuli that are perceived as stressors in the environment), such as wandering, restlessness, or calling out. (asha.org)
  • Carotid stenosis is associated with cognitive aging in addition to an elevated stroke risk, Halliday explained, "so might prophylactic interventions such as [carotid endarterectomy] prevent cognitive aging and hence dementia? (tctmd.com)
  • But researchers at Case Western Reserve University are imbedding the blocks with technology that may provide a clearer view of problems a child or adult may suffer due to developmental disabilities, brain trauma or dementia. (technologynetworks.com)
  • Read Full Scientific Article Our research team shows that baseline brain integrity (brain markers commonly seen with Alzheimer's Disease-Vascular Dementia) and cognitive function predict variability during a controlled period of anesthesia while having knee replacement surgery. (ufl.edu)
  • Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. (karger.com)
  • Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments. (karger.com)
  • One showed that telephone-based evaluation is sufficient to assess the cognitive reserve of leucine-rich glioma inactivated-1-antibody encephalitis patients, thereby diagnosing their dementia. (encephalitisjournal.org)
  • Objective To summarise evidence on the preventive effects of continuing education on mild cognitive impairment and Alzheimer's-type dementia in adults 45 years or older. (bmj.com)
  • Systematic reviews consistently reported a positive association between participation in cognitively stimulating leisure activities and reduced incidence of dementia and improved cognitive test performance. (bmj.com)
  • Conclusion Available results demonstrate that cognitive reserve increases through continuing education and show a positive association of cognitive leisure activities with both improved cognitive function and lower dementia incidence. (bmj.com)
  • The goal of this project is to advance our understanding of the mechanisms linking diabetes to dementia and to test the hypothesis that the risk effect of diabetes on the brain can be counteracted by a low vascular burden, healthy diet, cognitive reserve (high level of education and mental stimulation in occupation and leisure activities), and optimal antidiabetic medications. (ki-su-arc.se)
  • Olfactory deficits are common in old age and associated with adverse health outcomes, such as dementia and mortality. (ki-su-arc.se)
  • We're not yet at the stage of recommending anti-inflammatory medication as a preventative strategy for cognitive decline as we haven't got trial data on this," Walker said, "but I think we can say it is a good idea to lead a healthy lifestyle and try to avoid becoming hypertensive or diabetic or obese and that should lower our risk of developing dementia later in life. (medscape.com)
  • Delirium-an acute state of confusion associated with temporary, but reversible, cognitive impairments (Mahendra & Hopper, 2013). (asha.org)
  • Prior cohort studies, including ACCOF-1 and InCHIANTI, have shown that asymptomatic carotid stenosis is associated with cognitive deficits, as well as mobility impairments and increased fall risk. (tctmd.com)
  • The possibility of reversing cognitive and mobility impairments in patients with asymptomatic carotid stenosis ≥ 70% has been tested in preliminary studies. (tctmd.com)
  • Later in 2010, researchers defined epileptic encephalopathy as a condition where the epileptic activity itself may contribute to severe cognitive and behavioral impairments above and beyond what might be expected from the underlying pathology alone (e.g., cortical malformation), and that these can worsen over time. (medscape.com)
  • One Neurology Review titled 'Eating Disorders and Cognitive Function' cites, "Many memory impairments exist as a result from or cause of eating disorders. (odomhealthandwellness.com)
  • Which is the nature of deficits in patients with emotional impairments caused by brain lesions or other neuropsychiatric conditions? (frontiersin.org)
  • Cognitive impairments contribute significantly to inadequate functional recovery following illness episodes in bipolar disorder, yet data on treatment interventions are sparse. (psychiatrist.com)
  • M eta-analyses from independent research groups have confirmed that individuals with bipolar disorder show cognitive impairments that persist during euthymic intervals. (psychiatrist.com)
  • In schizophrenia, cognitive impairments are consistently associated with poor functional outcomes. (psychiatrist.com)
  • 10 Likewise, in 6 of 8 studies, cognitive impairments were linked to worse functioning in persons with bipolar disorder even after controlling for demographic, illness, and mood variables. (psychiatrist.com)
  • Infants with congenital toxoplasmosis often are asymptomatic, but eye disease, neurologic disease, or other systemic symptoms can occur, and cognitive deficits, learning disabilities, or visual impairments could develop later in life. (cdc.gov)
  • In addition, the relationship between social isolation, depressive symptoms typical of the change of life in old age, and cognitive impairment is very large. (neuronup.us)
  • The postsynaptic protein Shank3 (SH3 and multiple ankyrin repeat domains) is of particular interest, as the loss of a single allele of the SHANK3 gene is sufficient to cause profound cognitive symptoms in children. (jneurosci.org)
  • Cognitive impairment has been shown to be a source of disability and diminished quality of life that rivals physical symptoms. (themedicalxchange.com)
  • Cognitive impairment is a well-documented consequence of the neurodegeneration associated with MS. 1 The risk of cognitive impairment increases with disease progression, but it can occur independently of other symptoms. (themedicalxchange.com)
  • When PwMS with a pediatric onset are followed longitudinally, cognitive symptoms and physical disability do not necessarily advance at the same pace over time. (themedicalxchange.com)
  • A new brain-zapping technology may help ease the symptoms of attention deficit hyperactivity disorder ( ADHD ) in children without some of the side effects stimulant medications can cause, a small, preliminary study suggests. (medicinenet.com)
  • The elderly often present attributable to a reduction in mental, cognitive and phys- with somatic or non-specific symptoms rather than the ical abilities, increased probability of death among their typical symptoms of depression, such as low energy, friends or loved ones, retirement and loss of communi- fatigue, reduction in physical movements and cognitive cation with people. (who.int)
  • Symptoms including fatigue, anxie- deficits (5) . (who.int)
  • symptoms may reflect deficits in any part of the nervous system. (msdmanuals.com)
  • Symptoms of mild cognitive impairment (MCI) include memory loss, language disturbance (eg, difficulty finding words), attention deficit problems, and deterioration in visuospatial skills. (medscape.com)
  • Clarification of this issue would allow for the development of more complete and accurate theoretical models of ADHD, aide in the etiological determination of the disorder, and inform cognitive neuroscience of the structure of attentional processes in normal and abnormal development. (psu.edu)
  • It is characterized by a progressive decline in memory and other cognitive domains that are severe enough to interfere with daily living and independent functioning. (asha.org)
  • The term epileptic encephalopathy describes a heterogeneous group of epilepsy syndromes associated with severe cognitive and behavioral disturbances. (medscape.com)
  • An enhanced CR may lead to less cognitive deficits despite severe pathological lesions. (e-jmd.org)
  • In addition, the level of cognitive reserve has been found to be associated with different AN prognosis and therefore treatment may be altered based on the cognitive reserve, where individuals who may experience more severe neurospsychological deficits may need more rehearsal and repeated practice of skills during treatment. (odomhealthandwellness.com)
  • in other words, a broad cognitive deficit although less severe than those reported in persons with schizophrenia. (psychiatrist.com)
  • The initial and less severe the scientific literature on CS with older adults with NCD, in clinical condition is mild NCD, defined by evidence of mo- particular, regarding to the format, periodicity and duration of the derate cognitive impairment compared to a previous level of sessions. (bvsalud.org)
  • DBS is typically reserved for patients with severe tics that have the potential to cause serious injury. (medscape.com)
  • Treatment is reserved for acutely infected immunocompromised or pregnant people and people with severe disease. (cdc.gov)
  • Prior studies have identified that decline in characterized by relative decrement in incidence of cognitive function of HIV + patients were strongly the severe form of HAND (i.e. (who.int)
  • These disorders vary in their age of onset, developmental outcome, etiologies, neuropsychological deficits, electroencephalographic (EEG) patterns, seizure types, and prognosis, but all may have a significant impact on neurological development. (medscape.com)
  • a) they get lost daily in extremely familiar surroundings, (b) they report experiencing topographical disorientation from childhood, (c) they have no other cognitive complaints (i.e., attentional, perceptual, or memory issues), and (d) they do not report any brain injury or neurological disorders. (nature.com)
  • Cognitive deficits are not better explained by other mental disorders, such as major depressive disorder or schizophrenia (APA, 2013). (asha.org)
  • to demonstrate diagnostic overshadowing we determined the prevalence of attention deficit-hyperactivity disorders ( adhd ) in a cohort of children with a wide range of neurological disabilities. (brain-knowledge-engine.org)
  • Cognitive disorders are now considered an integral part of the picture of multiple sclerosis. (mdpi.com)
  • In this work, the history of the description of cognitive disorders of multiple sclerosis will be retraced by analyzing the possible reasons for the differences in attention they have received over time. (mdpi.com)
  • Depressive disorders in elderly people can affect their cognitive and physical abilities and nutritional status. (who.int)
  • This study aimed to determine the prevalence of depressive disorders in older Palestinians and its relationship with nutritional, functional and cognitive status. (who.int)
  • The presence of depressive disorders was also significantly associated with lower scores on the instrumental activities of daily living scale and the Montreal cognitive assessment tool, and with hypercholesterolaemia, chewing and swallowing difficulties and lack of appetite. (who.int)
  • Cognitive stimulation (CS) is a non-pharmacological therapy with good support for its ability to limit the progression of cognitive decline in elderly people with neurocognitive disorders (NCD) by stimulating cognitive function. (bvsalud.org)
  • Mild cognitive impairment (MCI) , also known as mild neurocognitive disorder (mild NCD), is a clinical syndrome that is characterized by a modest decline in one or more cognitive domains. (asha.org)
  • Over the next five years, some of these healthy individuals developed Mild Cognitive Impairment or Alzheimer's Disease. (bu.edu)
  • Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. (jamanetwork.com)
  • Purpose: Cognitive communication deficits can be difficult to assess in individuals with mild traumatic brain injury (mTBI). (usuhs.edu)
  • Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review. (alzforum.org)
  • Can Apathy in Mild Cognitive Impairment Predict Alzheimer's Disease? (medscape.com)
  • There is evidence that whether the child's home language is in a majority or minority situation, is valued in the community, and is used as a medium for literacy affects the child's linguistic and cognitive outcomes. (child-encyclopedia.com)
  • The important issues that follow from linguistic diversity are the cognitive and educational outcomes for bilingual children. (child-encyclopedia.com)
  • Cognitive outcomes of childhood primary CNS vasculitis. (intelquo.com)
  • Older adults have been reported to have increased susceptibility to the adverse effects of SARS-CoV-2 infection, such as fatal outcomes, cognitive decline, and changes in physical and/or mental health. (nature.com)
  • Cognitive testing at baseline and 8 weeks assessed primary efficacy outcomes. (psychiatrist.com)
  • Proof of principle: Preoperative cognitive reserve and brain integrity predicts intraindividual variability in processed EEG (Bispectral Index Monitor) during general anesthesia. (ufl.edu)
  • The study goes on to say, "The level of cognitive reserve predicts improvement in neuropsychological function including verbal memory, semantic fluency, basic auditory attention, and visuospatial construction. (odomhealthandwellness.com)
  • Therefore, we hypothesized that the presence of motor reserve (MR) in PD explains the individual differences in motor deficits despite similar levels of striatal dopamine depletion. (e-jmd.org)
  • Background: Parkinson's disease (PD) is characterized by motor deficits and brain alterations having a detrimental impact on balance, gait, and cognition. (lu.se)
  • There is a significant decline from previous levels of performance in one or more cognitive domains, including complex attention, executive function, learning and memory, language, perceptual motor, or social cognition (preferably documented by standardized testing or clinical assessment). (asha.org)
  • Which are the perceptual and cognitive mechanisms characterizing conscious and unconscious emotion processing? (frontiersin.org)
  • 2014). Early identification of MCI may enable the use of cognitive interventions to slow the progression of decline (Huckans et al. (asha.org)
  • These interventions from midlife onwards, they might prevent several years of cognitive aging for some of the patients, so this lack of overall effect does not preclude protection from carotid intervention," Halliday said. (tctmd.com)
  • This may be because most patients can be treated with less aggressive interventions, such as medication or cognitive-behavioral approaches. (medscape.com)
  • Participants underwent balance, gait, cognitive function, and structural magnetic resonance imaging assessments before and after the interventions. (lu.se)
  • A significant end out-of browse towards alterations in cognitive function as the i years is that attentional deficits might have a significant effect with the a mature individuals ability to means acceptably and you will alone for the day to day life. (arboristreportsaustralia.com.au)
  • Regardless of whether we looked at a composite cognitive function [endpoint] or looked at individual cognitive function domains, stenosis patients performed far worse than those without stenosis," Lal said. (tctmd.com)
  • In a small, nonrandomized, prospective study of 46 patients, which was published in 2011, cognitive function improved 6 months after revascularization with either stenting or carotid endarterectomy. (tctmd.com)
  • Additional evidence to inform this question may be forthcoming from CREST-2, which has cognitive function as a secondary endpoint. (tctmd.com)
  • Based on combined behavioral and neuroimaging (voxel-based morphometry) analyses of demographic, cognitive, and neural markers of aging and cognitive reserve proxy measures, we examine here predictors of variability in the age-related changes in attention function, indexed by ability to suppress salient distraction. (ox.ac.uk)
  • Predicted association between Alzheimer disease (AD) pathologic changes and global cognitive function. (jamanetwork.com)
  • Predicted association between neurofibrillary tangles and global cognitive function. (jamanetwork.com)
  • Education modifies the association of amyloid but not tangles with cognitive function. (jamanetwork.com)
  • Education modifies the relation of AD pathology to level of cognitive function in older persons. (jamanetwork.com)
  • The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study. (jamanetwork.com)
  • In a secondary analysis of the phase 3 trial, those randomized to the active agent, a modulator of sphingosine-1-phosphate (S1P) receptor function, had a lower risk of cognitive impairment and a greater likelihood of improvement on measures of processing speed than those in the placebo arm. (themedicalxchange.com)
  • The trial provides a framework for considering how to evaluate and monitor cognitive function as a therapeutic target. (themedicalxchange.com)
  • Individual differences in brain reorganization may be relevant to the variability at which cognitive function advances at the level of an individual person. (themedicalxchange.com)
  • For example, self-reported data from an online survey were used to examine the impact of the COVID-19 period on well-being, activity levels, sleep quality, and cognitive function 7 . (nature.com)
  • The neat thing about this study is that as well as showing a temporal relationship, we compared cognitive function in people to their own baseline, so we eliminate much of the bias that can occur in observational studies," Walker added. (medscape.com)
  • Participants were evaluated in person over five visits until 2011-2013 and received a serial cognitive assessment using measures of memory, executive function, and language at visits 2, 4, and 5 spanning 20 years. (medscape.com)
  • An interview-based questionnaire was used to obtain information on sociodemographic char- acteristics, nutritional habits, anthropometric measurements, cognitive function (using the Montreal cognitive assess- ment tool), and functional status (using activities of daily living and instrumental activities of daily living scales). (who.int)
  • In addition, an analysis of the first 200 patients enrolled in CREST-2 , showed evidence of cognitive impairment compared with 30,000 participants in the REGARDS study, a national cohort study exploring stroke risk factors in adults 45 years and older. (tctmd.com)
  • If keeping your brain active is a good way to prevent cognitive decline, then why did people such as Ronald Reagan and Norman Rockwell develop Alzheimer's disease? (bu.edu)
  • The concept of cognitive reserve (CR) in Alzheimer's disease (AD) explains the differences between individuals in their susceptibility to AD-related pathologies. (e-jmd.org)
  • CLEVELAND - Neuroscientists at Case Western Reserve University School of Medicine have made a dramatic breakthrough in their efforts to find a cure for Alzheimer's disease. (case.edu)
  • The researchers' findings, published in the journal Science , show that use of a drug in mice appears to quickly reverse the pathological, cognitive and memory deficits caused by the onset of Alzheimer's. (case.edu)
  • In particular, the researchers were struck by the speed with which bexarotene improved memory deficits and behavior even as it also acted to reverse the pathology of Alzheimer's disease. (case.edu)
  • Objective: To characterize the clinical cognitive phenotypes and severity of cognitive burden according to disease subtype in children with primary central nervous system vasculitis (cPACNS). (intelquo.com)
  • The suggestion that individuals with attention deficit hyperactivity disorder (ADHD) suffer from a subtle neurological dysfunction has existed throughout the history of modern clinical observations. (psu.edu)
  • However, the use of discourse analysis as a direct and sensitive metric of cognitive communication skills has shown promising clinical utility for other TBI severity levels. (usuhs.edu)
  • But not only are these factors related, but part of the decline attributed to age may also be due simply to a lack of cognitive stimulation . (neuronup.us)
  • in other words, the more cognitive stimulation a person has, the more autonomy he or she will demonstrate. (neuronup.us)
  • This concept is known as cognitive reserve , which is the amount of knowledge, cognitive resources and coping strategies that a person accumulates throughout their life: the richer the stimulation a person has received (education, culture, experiences, challenges…) the more likely it is that they will have a reserve that allows them to face the changes associated with ageing and, therefore, better cope with the cognitive deterioration inherent to aging. (neuronup.us)
  • It has been shown that deterioration slows down and deficits are milder if subjects have lived in enriched environments and if they continue to stimulate their abilities through cognitive stimulation practices and exercises. (neuronup.us)
  • Half of the kids underwent brain stimulation for 10 days while playing cognitive training video games. (medicinenet.com)
  • Discussion: Structural features of discourse production may serve as potential markers of cognitive communication deficits in mTBI. (usuhs.edu)
  • Higher blood levels of inflammatory markers in midlife were associated with greater cognitive decline many years later in the decades leading up to older adulthood, according to a new study. (medscape.com)
  • We wanted to investigate whether inflammatory markers much earlier in life are related to cognitive decline in older years," he said. (medscape.com)
  • They found that those with higher levels of inflammatory markers in midlife had steeper rates of cognitive decline over the next 20 years. (medscape.com)
  • Inherent in the notion of an epileptic encephalopathy is that limiting or suppressing EEG ictal and/or interictal activity may improve cognitive and behavioral outcome. (medscape.com)
  • Whereas behavioral observations of "inattention" reliably distinguish children with ADHD from non-ADHD children (1), determination of whether inattention is a cognitive hallmark that identifies ADHD children from their non-ADHD counterparts has been more elusive. (psu.edu)
  • There are various types of psychotherapies, such as Cognitive Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and psychoanalysis, among others. (diseasefix.com)
  • Higher apathy was predicted by poorer global cognitive performance, increased anxiety, and emotional dysregulation as measured by a higher ratio of low-to-high frequency heart rate variability. (nature.com)
  • Similarly, pediatric onset of MS is associated with cognitive impairment, so that children and adolescents with MS on average have poorer academic performance and lower intelligence quotient scores than healthy controls. (themedicalxchange.com)
  • And there are increasingly stable results demonstrating that stenosis in the carotid artery is associated with cognitive and mobility impairment," Lal explained, suggesting that how "asymptomatic" is defined in the context of carotid stenosis should be reconsidered based on the evidence of cognitive impairment in this setting. (tctmd.com)
  • There is, however, a deficit of research looking at the relationship between obsessive-compulsive disorder (OCD) severity, nutrient intake and dietary quality. (cambridge.org)
  • Thus, we provide here novel experimental evidence supporting Robertson's theory of a right lateralized neural basis for cognitive reserve. (ox.ac.uk)
  • Results showed that scores before and during the pandemic were the same in memory and attention, whereas global cognitive, executive, and language functions improved. (nature.com)
  • However, emotional signals can also implicitly drive human behavior without reaching a full cognitive awareness. (frontiersin.org)
  • Data gathered in a novel transgenic mouse suggest that Shank3a deficiency synergizes with AD neuropathology to induce cognitive impairment, consistent with a causal role in AD. (jneurosci.org)
  • The Ginkgo tree has been used in Traditional Chinese Medicine for over 4,000 years.The German Commission E 'approves' Ginkgo Biloba extracts for effective therapy in cases of memory deficits,depression,impaired concentration,dizziness, tinnitus or migraine. (chisuk.org.uk)
  • Some of the main deficits observed in old age affect information processing , information learning and retrieval (memory) , problem solving and speed of response . (neuronup.us)
  • Conclusion: Children with small-vessel CNS vasculitis are more likely to demonstrate deficits in intellectual functioning than are those with large-vessel disease, and children with both types of CNS vasculitis demonstrate relatively poor working memory and processing speed. (intelquo.com)
  • Although a modest decline in memory and cognitive skills is to be expected, some changes may be indicative of a larger issue. (medscape.com)
  • Cognition, reserve, and amyloid deposition in normal aging. (jamanetwork.com)
  • Compared to placebo, WSE provided significant benefits for 3 cognitive tasks: digit span backward ( P = .035), Flanker neutral response time ( P = .033), and the social cognition response rating of the Penn Emotional Acuity Test ( P = .045). (psychiatrist.com)
  • The Cognition, Brain, and Aging (COBRA) project examines the relationship of the neurotransmitter dopamine (DA) and other brain parameters (i.e., grey- and white matter volumes, white-matter microstructure, functional activation patterns during rest and task performance, perfusion) to cognitive performance and change in aging, with a chief focus on longitudinal trajectories of DA availability and how those map onto corresponding cognitive paths. (ki-su-arc.se)
  • Recent studies have shown that social contact is the most important factor against cognitive decline in the elderly. (neuronup.us)
  • Active (Advanced Cognitive Studies for Independent and you will Vital Elderly), a study used between 1999 and you will 2001 where dos,802 individuals years 65 to 94, suggests that the clear answer is "yes. (arboristreportsaustralia.com.au)
  • Deficits included in of a lot opportunities, for instance the Stroop task and this strategies choosy attract, are going to be largely associated with an over-all reducing of information handling into the the elderly in lieu of so you can selective desire deficits per se. (arboristreportsaustralia.com.au)
  • Furthermore, PTSD may contribute to verbal fluency deficits in individuals with mTBI. (usuhs.edu)
  • Demyelination should be considered in any patient with unexplained neurologic deficits. (msdmanuals.com)
  • importantly, we test the specific hypothesis that the presence of DTD is significantly related to the inability of the individuals to form a mental representation of the spatial surroundings (i.e., a cognitive map). (nature.com)
  • The results of this study in human brain samples and in transgenic mice are consistent with the hypothesis that Shank3 deficiency makes a key contribution to cognitive impairment in AD. (jneurosci.org)
  • Cognitive reserve measured by proxies of cognitively enriching life experiences, such as education, occupation, and leisure activities, is thought to mitigate the effects of the aging process and account for variability in trajectories of cognitive decline. (ox.ac.uk)
  • In a MRI study of 234 PwMS of which 41% had cognitive deficits, cortical grey matter volume loss was the only consistent baseline predictor of cognitive decline across MS subtypes, but predictors differed for those with early-stage RRMS, in whom white matter integrity damage predicted cognitive deficits, relative to those with late-stage RRMS or progressive MS, in whom cortical atrophy was a significant predictor. (themedicalxchange.com)
  • Cognitive deficits do not occur exclusively in the context of delirium. (asha.org)
  • If we trace the history of the accounts of this disease, from the early descriptions by Jean-Martin Charcot, the first to provide systematic characteristics of multiple sclerosis, to present-day accounts, reports of cognitive disturbances have demonstrated an alternating trend. (mdpi.com)
  • Cognitive disturbances were identified in the beginning, quite clearly for the times. (mdpi.com)
  • Finally, since the 1980s, cognitive disturbances have been the subject of increasingly in-depth studies, and are currently assumed to be a very important consequence of multiple sclerosis. (mdpi.com)
  • Individuals with DTD report a lifelong selective inability to orient despite otherwise well-preserved general cognitive functions, and the absence of any acquired brain injury or neurological condition, with general intelligence reported to be within the normal range. (nature.com)
  • While performing interactive tasks, as a group, the individuals with DTD performed slightly worse on a scene-based perspective-taking task, and, notably struggled to solve tasks that demand the generation and use of a cognitive map. (nature.com)
  • Therefore, despite getting lost in extremely familiar surroundings, individuals with DTD do not seem to differ in their general cognitive abilities from individuals who have no orientation problems. (nature.com)
  • We first found a 30%-50% postmortem loss of SHANK3a associated with cognitive decline in the parietal cortex of individuals with AD. (jneurosci.org)
  • Most individuals with secondary progressive multiple sclerosis (SPMS) have or will develop measurable cognitive impairment. (themedicalxchange.com)
  • 2 In these asymptomatic individuals, who met criteria for radiologically isolated syndrome (RIS), cognitive impairment correlated with higher T1 lesion volume and lower cortical volume. (themedicalxchange.com)
  • 3.0 for at least 15 years after diagnosis, even though cognitive impairment in these individuals is an adverse prognostic marker. (themedicalxchange.com)
  • 11 Importantly, in previously employed individuals with bipolar disorder who had experienced a manic episode, changes in specific cognitive test scores robustly predicted occupational recovery 3 months after symptomatic recovery. (psychiatrist.com)
  • According to Elizabeth B. Dowdell and Brianne Q. Clayton, sleep-deprived college students performed significantly worse than peers who had adequate sleep on cognitive skills. (wikipedia.org)
  • The training was formal education, low baseline CD4, and un- given by the primary investigator on how to employment were found to be significantly associated administer the cognitive assessment tool. (who.int)
  • Conversely, cognitive impairment is not reported in other PwMS with advanced physical disability. (themedicalxchange.com)
  • Early childhood development (ECD) comprises the physical, cognitive, motor and socioemotional growth of children up to 8 years of age (1,2). (who.int)
  • David's dissertation work focused on (1) the further validation of a rodent Target Detection Task (rTDT) analogous to human Continuous Performance Tasks, (2) the further validation of the embryonic kynurenine (EKYN) animal model of schizophrenia, and (3) the use of EKYN deficits in the rTDT as a platform to assess the efficacy of cognitive training via prior experience in cognitively demanding tasks. (osu.edu)
  • Results showed that after adjusting for demographic variables, vascular risk factors, and comorbidities, each standard deviation (SD) increase in midlife inflammation composite score was associated with an additional 20-year decline of −0.035 SD on the cognitive composite score. (medscape.com)
  • Cognitive impairment is already common noted in clinically isolated syndrome (CIS), reported in up to 25% of those with this condition, 3 but the risk increases to 45% in those who progress to relapsing MS (RMS) and then as high as 75% in those with SPMS 4 (Figure 1 ). (themedicalxchange.com)
  • Finally, the lack of longitudinal studies with neuropsychological data collected before the pandemic made it impossible to detect potential changes in cognitive functioning and/or mood, limiting the resulting findings to short-term effects and neglecting the crucial role of "baseline" performance. (nature.com)
  • detect the optimal antidiabetic medications that may retard cognitive decline. (ki-su-arc.se)
  • Screening for Attention Deficit Hyperactivity Disorder in Young Autistic Adults: The Diagnostic Accuracy of Three Commonly Used Questionnaires. (brain-knowledge-engine.org)
  • The Bruno lab worked on exploring animal models of the cognitive deficits present in schizophrenia. (osu.edu)
  • 11 Greater cognitive decline was associated with greater structural damage at baseline in both groups, but one did not reliably predict the other in any individual patient. (themedicalxchange.com)
  • Where is the "attention deficit" in ADHD? (psu.edu)
  • Dive into the research topics of 'Where is the "attention deficit" in ADHD? (psu.edu)
  • Marked by trouble concentrating, sitting still and/or controlling impulsive behaviors, ADHD affects about 5.3 million children, according to Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD). (medicinenet.com)
  • Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD) has more on ADHD treatments. (medicinenet.com)
  • None of the other cognitive tasks showed significant between-group differences. (psychiatrist.com)
  • Here, we report the findings of a 10-year-long study investigating the behavioural and cognitive mechanisms of DTD in a large sample of 1211 cases. (nature.com)