• Soil
  • Arbuscular mycorrhizas (AM) play different roles in plant Zn nutrition depending on whether the soil is Zn-deficient (AM enhancement of plant Zn uptake) or Zn-toxic (AM protection of plant from excessive Zn uptake). (springer.com)
  • We undertook a glasshouse experiment to study the interactive effects of P and Zn on AM colonisation, plant growth and nutrition, focusing on the two extremes of soil Zn concentration-deficient and toxic. (springer.com)
  • Bi YL, Li XL, Christie P (2003) Influence of early stages of arbuscular mycorrhiza on uptake of zinc and phosphorus by red clover from a low-phosphorus soil amended with zinc and phosphorus. (springer.com)
  • Cavagnaro TR (2008) The role of arbuscular mycorrhizas in improving plant zinc nutrition under low soil zinc concentrations: a review. (springer.com)
  • To evaluate the physiological responses of wheat to zinc (Zn) fertilizer application under drought stress, pot, and field experiments were conducted on wheat plants grown under different soil moistures and treated with soil and foliar Zn applications. (frontiersin.org)
  • Increasing the amount of zinc in the soil and thus in crops and animals is an effective preventive measure. (wikipedia.org)
  • It can be brought about by a combination of factors including: a specific mineral deficiency in the soil, such as iron, magnesium or zinc deficient nitrogen and/or proteins a soil pH at which minerals become unavailable for absorption by the roots poor drainage (waterlogged roots) damaged and/or compacted roots pesticides and particularly herbicides may cause chlorosis, both to target weeds and occasionally to the crop being treated. (wikipedia.org)
  • Soil contains zinc in 5-770 ppm with an average 64 ppm. (wikipedia.org)
  • concentrations
  • some soils (sandy soils, histosols and soils developed from highly weathered parent material) have low total zinc concentrations, and others have low plant-available zinc due to strong zinc sorption (calcareous soils, highly weathered soils, vertisols, hydromorphic soils, saline soils). (wikipedia.org)
  • Although zinc requirements vary among crops, zinc leaf concentrations (on a dry matter basis) in the range 20 to 100 mg/kg are adequate for most crops. (wikipedia.org)
  • proteins
  • Only a handful of studies have been conducted using bone marrow-derived MSCs (BM-MSCs) to address questions regarding zinc and its cellular regulation in stem cells through proteins such as zinc transporters [ 21 , 22 ]. (hindawi.com)
  • Zinc occurs in plants as a free ion, as a complex with a variety of low molecular weight compounds, or as a component of proteins and other macromolecules. (wikipedia.org)
  • Initial selection efforts utilized phage display to select proteins that bound a given DNA target from a large pool of partially randomized zinc-finger arrays. (wikipedia.org)
  • adult
  • Regeneration of t-cell helper function in zinc deficient adult a/j mic" by jardieu P. Depasquale, P J. Fraker et al. (jax.org)
  • Regeneration of t-cell helper function in zinc deficient adult a/j mice. (jax.org)
  • Most chelatable zinc is contained in vesicles localized in the presynaptic terminals of the dentate granule cells that form the mossy fiber tracts of the hippocampus [ 13 , 14 ], a region where neurogenesis and neural migration actively occurs in the adult brain [ 15 , 16 ]. (hindawi.com)
  • A deficiency in the zinc mainly results in skin disorders in adult cats, but also results in growth oddities. (wikipedia.org)
  • diets
  • Experts say as many as two billion people around the world have diets deficient in zinc - and studies at Oregon State University and elsewhere are raising concerns about the health implications this holds for infectious disease. (theheartysoul.com)
  • affects
  • Zinc also affects the growth factor control of cell division, especially in cells regulated by insulin-like growth factor-I (IGF-I) [ 10 ] or nerve growth factor (NGF) [ 11 ]. (hindawi.com)
  • organic
  • Soils low in organic matter (such as where topsoils have been removed), and compacted soils that restrict root proliferation also have a high risk of zinc deficiency. (wikipedia.org)
  • Foliar applications of zinc as zinc sulphate or as zinc chelate (or other organic complexes) are also widely used, especially with fruit trees and grape vines. (wikipedia.org)
  • A variety of zinc compounds are commonly used, such as zinc carbonate and zinc gluconate (as dietary supplements), zinc chloride (in deodorants), zinc pyrithione (anti-dandruff shampoos), zinc sulfide (in luminescent paints), and zinc methyl or zinc diethyl in the organic laboratory. (wikipedia.org)
  • vitamin
  • Supplementing vitamin A with retinol to a deficient cat, and feeding a balanced diet to a cat with hypervitaminosis A will treat the underlying nutritional disorder. (wikipedia.org)
  • The brain retains its thiamine content in the face of a vitamin-deficient diet with great tenacity, as it is the last of all nervous tissues studied to become depleted. (wikipedia.org)
  • gene expression
  • Furthermore, we showed that zinc promoted neurite outgrowth via the inactivation of RhoA and led to the induction of neuronal gene expression (MAP2 and nestin) in differentiated stem cells. (hindawi.com)
  • Iron
  • With the help of these studies, iron and zinc treatment instead of only iron replacement may be considered in cases of iron deficiency. (tjh.com.tr)
  • Zinc is the second most plentiful transition metal after iron in the central nervous system [ 12 ]. (hindawi.com)
  • Corrosion-resistant zinc plating of iron (hot-dip galvanizing) is the major application for zinc. (wikipedia.org)
  • mainly
  • Taken together, zinc promoted AD-MSC proliferation and affected neuronal differentiation, mainly by increasing neurite outgrowth. (hindawi.com)
  • proliferation
  • Zinc is an essential element required for cell division, migration, and proliferation. (hindawi.com)
  • Under zinc-deficient conditions, proliferation and differentiation of neural progenitors are significantly impaired. (hindawi.com)
  • We initially examined the effect of zinc on stem cell proliferation at the undifferentiated stage. (hindawi.com)
  • Zinc chelation inhibited AD-MSC proliferation via downregulation of ERK1/2 activity. (hindawi.com)
  • A recent study also demonstrated that gestational zinc deficiency impaired fetal neuronal progenitor cell proliferation by reducing the ERK1/2 signaling pathway [ 20 ]. (hindawi.com)
  • Methods
  • Without methods to account for this "context dependence", the standard modular assembly procedure often fails unless it is used to recognize sequences of the form (GNN)N. Numerous selection methods have been used to generate zinc-finger arrays capable of targeting desired sequences. (wikipedia.org)
  • commonly
  • The most commonly used linker sequences between the zinc finger domain and the cleavage domain requires the 5' edge of each binding site to be separated by 5 to 7 bp. (wikipedia.org)
  • finger
  • Zinc finger nuclease mediated gene targeting of a single copy gp91 phox therapeutic minigene into one allele of the "safe harbor" AAVS1 locus in X-CGD iPSCs without off-target inserts resulted in sustained expression of gp91 phox and substantially restored neutrophil ROS production. (bloodjournal.org)
  • Our findings demonstrate how precise gene targeting may be applied to correction of X-CGD using zinc finger nuclease and patient iPSCs. (bloodjournal.org)
  • Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. (wikipedia.org)
  • The DNA-binding domains of individual ZFNs typically contain between three and six individual zinc finger repeats and can each recognize between 9 and 18 basepairs. (wikipedia.org)
  • If the zinc finger domains perfectly recognize a 3 basepair DNA sequence to generate a 3-finger array that can recognize a 9 basepair target site. (wikipedia.org)
  • Other procedures can utilize either 1-finger or 2-finger modules to generate zinc-finger arrays with six or more individual zinc fingers. (wikipedia.org)
  • This system combines pre-selected pools of individual zinc fingers that were each selected to bind a given triplet and then utilizes a second round of selection to obtain 3-finger arrays capable of binding a desired 9-bp sequence. (wikipedia.org)
  • This system was developed by the Zinc-Finger Consortium as an alternative to commercial sources of engineered zinc-finger arrays. (wikipedia.org)
  • see: Zinc finger chimera for more info on zinc finger selection techniques) The non-specific cleavage domain from the type IIs restriction endonuclease FokI is typically used as the cleavage domain in ZFNs. (wikipedia.org)
  • Standard ZFNs fuse the cleavage domain to the C-terminus of each zinc finger domain. (wikipedia.org)
  • Zinc finger nucleases have also been used in a mouse model of haemophilia and a clinical trial found CD4+ human T-cells with the CCR5 gene disrupted by zinc finger nucleases to be safe as a potential treatment for HIV/AIDS. (wikipedia.org)
  • essential
  • Zinc is an essential element, which is necessary for organ and tissue growth and development [ 8 ]. (hindawi.com)
  • Zinc deficiency occurs when plant growth is limited because the plant cannot take up sufficient quantities of this essential micronutrient from its growing medium. (wikipedia.org)
  • Zinc is an essential micronutrient which means it is essential for plant growth and development, but is required in very small quantities. (wikipedia.org)
  • Zinc plays an essential role in numerous biochemical pathways. (wikipedia.org)
  • Zinc is an essential mineral, including to prenatal and postnatal development. (wikipedia.org)
  • treatment
  • Zinc can also be supplied as a seed treatment, or by root-dipping of transplant seedlings. (wikipedia.org)
  • The use of zinc in the treatment of anorexia has been advocated since 1979 by Bakan. (wikipedia.org)
  • A 1994 trial showed that zinc doubled the rate of body mass increase in the treatment of anorexia nervosa. (wikipedia.org)
  • clinical
  • A cat will be deficient for many months prior to seeing clinical signs in the skin, after which the skin will become scaly, and greasy while the coat will become dull. (wikipedia.org)
  • women
  • A review of pregnancy outcomes in women with acrodermatitis enteropathica, reported that out of every seven pregnancies, there was one abortion and two malfunctions, suggesting the human fetus is also susceptible to the teratogenic effects of severe zinc deficiency. (wikipedia.org)
  • evidence
  • The mines of Rajasthan have given definite evidence of zinc production going back to the 6th century BC. (wikipedia.org)
  • To date, the oldest evidence of pure zinc comes from Zawar, in Rajasthan, as early as the 9th century AD when a distillation process was employed to make pure zinc. (wikipedia.org)
  • Effect
  • Promoting Effect of Foliage Sprayed Zinc Sulfate on Accumulation of Sugar and Phenolics in Berries of Vitis vinifera cv. (mdpi.com)
  • thus
  • According to a study published in PubMed, the accuracy of the zinc taste test in individual cases ranges between 70 and 100 percent, thus offering a pretty fair idea of zinc deficiency that can be followed up with blood testing if needed. (theheartysoul.com)
  • include
  • Other source minerals for zinc include smithsonite (zinc carbonate), hemimorphite (zinc silicate), wurtzite (another zinc sulfide), and sometimes hydrozincite (basic zinc carbonate). (wikipedia.org)
  • large
  • Zinc metal was not produced on a large scale until the 12th century in India, though it was known to the ancient Romans and Greeks. (wikipedia.org)