• Her primary interests are in cardiac arrhythmias, engaging full range of catheter-based endocardial and epicardial ablation therapies, complex ablations, pacemakers, defibrillator implants, and lead extractions. (mayoclinic.org)
  • Arrhythmias are one of the leading causes of heart disease deaths, and the number of people living with disorders caused by abnormal heart rhythms continues to rise," said Dr. Gadi Silberman, electrophysiologist at TMH. (tallahassee.com)
  • A pacemaker (or artificial pacemaker , not to be confused with the heart's natural pacemaker ) is an electronic device which is used to treat cardiac arrhythmias . (wikidoc.org)
  • Electrolytes, calcium, and magnesium: Severe metabolic acidosis, hypokalemia, hyperkalemia, hypocalcemia, and hypomagnesemia are some of the conditions that can increase the risk for arrhythmia and sudden death. (medscape.com)
  • Subtherapeutic levels of these drugs in patients being treated for specific cardiac conditions also can lead to an increased risk for arrhythmia. (medscape.com)
  • In this review, we present the current experimental and clinical data on the effect of these therapeutic modalities on cardiac electrophysiology and their potential role in arrhythmia management. (aerjournal.com)
  • Arrhythmia & Electrophysiology Review 2021;10(2):77-84. (aerjournal.com)
  • INTRODUCTION - Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in clinical practice. (medilib.ir)
  • The family background of the young boy revealed that a sister had suffered sudden cardiac death (SCD), even though she had been treated with pacemaker implantation and amiodarone. (bvsalud.org)
  • From the first pacemaker to the latest cardiac technology, follow us through the years and see what these innovations have made possible for you-and your patients. (bostonscientific.com)
  • In 1957, a pacemaker power failure leading to the death of a baby prompted Earl Bakken, an electrical engineer design the first battery-operated pacemaker the same year. (wikidoc.org)
  • The Danish Society of Clinical Pharmacology was founded in 1976, and mainly thanks to the persistent efforts of the society, clinical pharmacology became an independent medical speciality in Denmark in 1996. (bvsalud.org)
  • CLINICAL INTERESTS: Dr. Olgin is a Cardiologist and a Cardiac Electrophysiologist. (ucsf.edu)
  • Dr. Olgin's clinical research has focused on atrial fibrillation and sudden cardiac death mechanisms, epidemiology, genetics and interventions. (ucsf.edu)
  • Clinical electrophysiology 2023. (ucsf.edu)
  • JACC: Clinical Electrophysiology. (elsevierpure.com)
  • Dr. Duchesne is a clinical investigator, involved with multiple international clinical trials studying novel advances in the diagnosis and treatment of cardiac disease. (ottawaheart.ca)
  • The ingestion of alcohol may slow down the Cardiac conduction system, which is an important system for managing the Circulatory system. (wikipedia.org)
  • Autonomic and hormonal input modulate multiple facets of cellular electrophysiology - action potential duration, ion channel kinetics and intracellular calcium dynamics (just to name a few) - which translate into macroscopic manifestations of autonomic modulation such as heart rate variability, atrioventricular (AV) conduction time and QT interval variability. (aerjournal.com)
  • It was long after the concept of heart block from Chinese physician Pien Ch'io that the treatment was sought, due to the scarce knowledge of the details of the cardiac conduction. (wikidoc.org)
  • Dr. Cha is currently the Director of Cardiac Device Services at Mayo Clinic Rochester and is leading the service in various advanced technologies including leadless pacemakers, leadless cardiac resynchronization therapies, and subcutaneous implantable cardioverter defibrillators (ICD). (mayoclinic.org)
  • The Heart Rhythm Clinic is outfitted with 30 patient exam rooms, more than double the program's former outpatient capacity, and nine device rooms, where electrophysiologists routinely monitor and care for patients with implantable devices, such as pacemakers, cardiac defibrillators and loop recorders, that work to stabilize irregular heartbeats. (tallahassee.com)
  • Implantation of cardiac implantable electronic devices (CIED), such as pacemakers and implantable cardioverter-defibrillators (ICD), can be life-saving as they can restore brady - and tachyarrhythmias [1]. (fortunejournals.com)
  • Collaboration among citizens, professionals, communities, and organizations is key to survival from sudden cardiac arrest. (citizencpr.org)
  • Since its inception, CCPRF has sought to "strengthen the Chain of Survival," a metaphor used to define the "series of actions" that improves the chance of survival for thousands of victims of sudden cardiac arrest. (citizencpr.org)
  • Notably, autonomic stimulation is also a potent modulator of cardiac electrophysiology. (aerjournal.com)
  • Normally, cardiac neurohormonal regulation is accomplished through the balanced effects of sympathetic and parasympathetic autonomic stimulation, along with the hormonal regulation of the renin-angiotensinaldosterone system (RAAS). (aerjournal.com)
  • Effect of long term physical training on heart rate variability, Computers in Cardiology, September 8-11, 1996, 17-20, doi:10.1109/CIC.1996.542462 . (flutopedia.com)
  • However, literature concerning CVS in dialysis patients with a cardiac implantable electronic device is scarce. (fortunejournals.com)
  • In the ATRIA study, it was estimated that 2.3 million adults in the United States had AF in 1996 and 1997, and that this will increase to 5.6 million by the year 2050, with more than 50 percent being more than 80 years of age [ 11 ]. (medilib.ir)
  • 1 Therefore, it is no surprise that neurohormonal regulation of cardiac electrophysiology is an area of active investigation for its potential antiarrhythmic effects. (aerjournal.com)
  • Cardiac vagal tone, which represents the contribution of the parasympathetic nervous system to cardiac regulation, is acknowledged to be linked with many phenomena relevant for psychophysiological research, including self-regulation at the cognitive, emotional, social, and health levels. (frontiersin.org)
  • They may have their onset at any time from childhood to middle age, and they can vary in severity from mild chest discomfort or palpitations with or without syncope to severe cardiopulmonary compromise and cardiac arrest. (medscape.com)
  • He also has active studies in understanding the remodeling that occurs in the ventricle in the setting of heart failure and myocardial infarction to create the substrate for sudden death and ventricular tachycardia and fibrillation. (ucsf.edu)
  • This difference was mainly due to the reduction of myocardial infarction and bailout use of GP IIb/IIIa inhibitors, with no significant effect on TVR or death. (jacc.org)
  • In 1957 Dr. William L. Weirich's publication demonstrated the restoration of heart rate , cardiac output , and mean aortic pressures in animals with complete heart block through the use of a myocardial electrode. (wikidoc.org)
  • A decrease in the ejection fraction and worsening wall motion abnormalities upon exercise echocardiography in patients who have had an MI has been suggested to confer increased risk of cardiac death. (medscape.com)
  • The Multi-Center Post-Infarction Research Group provided evidence that resting ejection fraction was the most important noninvasive predictor of SCD and other cardiac events in patients with MI. (medscape.com)
  • Therefore, the neurological criteria of death are still lacking generally accepted scientific basis and should not be used in medicine and in the legal systems as a basis for diagnosing comatose/having no brainstem reflexes/apneic patients dead. (umk.pl)
  • 1996). "Prognosis among patients with out-of-hospital cardiac arrest judged as being caused by deterioration of obstructive pulmonary disease" . (wikidoc.org)
  • Left atrial volume (LAV) index has been proposed in the past as a predictor of POAF in patients undergoing cardiac surgery. (jafib.com)
  • 4 - 7 Moreover, almost all of these studies included patients undergoing any type of cardiac surgery and extending their results to the higher risk group undergoing AVR may not be accurate. (jafib.com)
  • 8 , 9 , 10 In patients undergoing cardiac surgery LAV index has been shown to be strongest predictor of POAF. (jafib.com)
  • Patients are at increased risk for death, heart failure, hospitalization, and thromboembolic events [ 1-3 ]. (medilib.ir)
  • However, transvenous cardiac device placement can lead to severe vascular and/or infectious complications, especially in vulnerable populations such as dialysis patients [7,8]. (fortunejournals.com)
  • Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/ARVC) is an important cause of sudden cardiac death in young adults, accounting for 11% of all cases and 22% of cases among athletes. (medscape.com)
  • 2010). "Factors associated with pulseless electric activity versus ventricular fibrillation: the Oregon sudden unexpected death study" . (wikidoc.org)
  • 4 In reality, the intrinsic cardiac nervous system, composed of several ganglia located primarily posterior to the atria, likely acts as a 'little brain' of the heart - it provides efferent input to the myocardium, collects afferent signals on a beat-to-beat basis and performs some integrative functions on its own, all under the tonic modulation of extrinsic sympathetic and parasympathetic input (see Figure 1 ). (aerjournal.com)
  • Despite treatment for MALA, he went into refractory cardiac arrest and was connected to venoarterial extracorporeal membrane oxygenation (VA-ECMO). (bvsalud.org)
  • Taken together these studies suggests that inhibiting α2δ-1 signaling may have therapeutic promise to reduce cell death and network reorganization associated with insult-induced DCMs. (eneuro.org)
  • In the year 2000, the World Health Organization (WHO) identified major depressive disorder (MDD) as the fourth ranked cause of disability and premature death globally and projected that by 2020 MDD and ischemic heart disease will be the two most important causes of disability worldwide [ 1 , 2 ]. (hindawi.com)
  • Psychophysiological research integrating heart rate variability (HRV) has increased during the last two decades, particularly given the fact that HRV is able to index cardiac vagal tone. (frontiersin.org)
  • Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures. (bvsalud.org)
  • Located at 2100 Centerville Road, near the intersection of Centerville Road and Blair Stone Road, the Heart Rhythm Clinic is an unprecedented expansion to the Big Bend's longest-standing, largest and most advanced electrophysiology program, now dubbed the Tallahassee Memorial Heart Rhythm Program. (tallahassee.com)
  • The Heart Rhythm Clinic is the latest addition to the Heart & Vascular Center's Heart Rhythm Program, which TMH launched in 1996 with founding physician, Dr. Marilyn Cox. (tallahassee.com)
  • The Heart Rhythm Clinic is complemented by the Tallahassee Memorial Heart & Vascular Center's Electrophysiology Lab (EP Lab), located within the Main Hospital. (tallahassee.com)
  • [ 1 ] Currently, Wolff-Parkinson-White (WPW) syndrome is defined as a congenital condition involving abnormal conductive cardiac tissue between the atria and the ventricles that provides a pathway for a reentrant tachycardia circuit, in association with supraventricular tachycardia (SVT). (medscape.com)
  • He also designed the first catheter-electrode for cardiac stimulation. (wikidoc.org)
  • The heightened level of acetaldehyde this syndrome causes can result in mitochondrial dysfunction, valvular disease, oxidative damage, cell death, lowered effects of cardioprotective molecules, and an altered calcium transport and protein synthesis system. (wikipedia.org)
  • 14, 15, 16] In some cases, mutation in the SCN5A gene may cause dysfunction in the cardiac voltage-gated sodium channel (Nav1.5), resulting in cardiomyopathy. (medscape.com)
  • In addition to its short and long-term neurological consequences, the COVID-19-related brainstem dysfunction compromises the adaptive response to stress and contributes to organ failure and death. (scientificarchives.com)
  • Cardiac magnetic resonance imaging (CMRI) to assess tissue characteristics and a 5-year risk score model has been proposed. (medscape.com)
  • VA-ECMO should be considered a rescue therapy alongside treatment with CVVHD in case of cardiac arrest due to severe MALA. (bvsalud.org)
  • Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death. (umk.pl)
  • More specifically, in this paper we refer to cardiac vagal tone as assessed by HRV measurement (also referred to as cardiac vagal control, given it reflects the contribution of the vagus nerve to cardiac functioning). (frontiersin.org)
  • The outbreak of the COVID-19 virus in 2019 had rapidly developed into a global pandemic, causing more than 6.8 million deaths and impacting the. (annals.edu.sg)
  • Post-operative atrial fibrillation (POAF) is one of the most common arrythmias after cardiac surgery with an increased mortality, stroke and prolonged hospital stay. (jafib.com)
  • There have been many studies in the literature identifying at least 17 pre-operative risk factors for POAF in various patient populations undergoing cardiac surgery. (jafib.com)
  • Journal of cardiac surgery. (wustl.edu)
  • Voulgari Ch, Papadogiannis D, Tentolouris N. Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies. (ter-arkhiv.ru)
  • The proposal was accepted by the medical, legal, religious and political circles in spite of the lack of any explanation why the irreversible coma combined with the absence of brainstem reflexes, including the respiratory reflex might be equated to death. (umk.pl)
  • The evolution of ECCU into the Cardiac Arrest Survival Summit will continue to provide the quality content and speakers you expect, and now include action-oriented programs and dynamic new content that brings together a broader range of partners working on initiatives to INFORM, MOTIVATE AND ACTIVATE our global community. (citizencpr.org)
  • Racial differences in the incidence of cardiac arrest and subsequent survival. (wikidoc.org)
  • In conclusion, it is possible to simulate the cardiac effects of methadone, yet several elements influence the approach uncertainty including but not limited to biophysically details model of cardiac electrophysiology, exposure data, and input parameters. (bvsalud.org)
  • A number of studies have demonstrated that the use of 2-dimensional echocardiogram to evaluate left wall motion abnormalities after an acute MI (using the LV wall-motion score index) is useful in predicting the risk for major cardiac events, including sudden death. (medscape.com)
  • A larger defect has been associated with greater risk for future cardiac events. (medscape.com)
  • In the context of the discussion about the neurological criteria for death, some authors follow the idea of Plato, that human being is the soul or mind, and the body does not belong to the human essence. (umk.pl)
  • Strokes and cardiac arrest can also occur in people with this syndrome. (wikipedia.org)
  • We confirm that Brugada syndrome is the same entity as sudden night death, highly prevalent in Southeast Asian countries (Thailand, Philippines and Japan), both of which share mutations in the same gene: SCN5A. (bvsalud.org)
  • He did Postgraduate Fellowship Training in Internal Medicine at the University of Toronto, and was recognized as a specialist in internal medicine by the Royal College of Physicians and Surgeons of Canada (FRCPC) in 1996. (ottawaheart.ca)
  • Here, we used mice with a genetic deletion of α2δ‐1 to determine how α2δ‐1 contributes to cell death, elevated excitatory synapse number, and in vitro network function after FL and to examine the molecular specificity of GBP's effects. (eneuro.org)
  • A predictive performance study was conducted using the simulation platform Cardiac Safety Simulator to mimic five literature studies using their described study conditions. (bvsalud.org)
  • Aside from respiratory depression, methadone is known to cause QT-prolongation, which may lead to sudden cardiac death. (bvsalud.org)