Non-psychoactive use of plants in the genus is usually done for medicinal purposes, and the alkaloids present in some species have long been considered traditional medicines in both the New and Old Worlds due to the presence of the alkaloids scopolamine and atropine, which are also produced by Old World plants such as Hyoscyamus niger, Atropa belladonna, and Mandragora officinarum. (wikipedia.org)
The tropane alkaloidsatropine, scopolamine, and hyoscyamine are highly anticholinergic compounds found in a number of plants. (medscape.com)
Scopolamine, acting as an antagonist at both peripheral and central muscarinic receptors, is thought to be the primary compound responsible for the toxic effects of these plants. (medscape.com)
Common examples of deliriants include plants of the genera Datura and Brugmansia (both containing scopolamine ) as well as higher than recommended dosages of diphenhydramine ( Benadryl ). (wikipedia.org)
Tropane alkaloids (TA) including anisodamine, anisodine, hyoscyamine and scopolamine are a group of important anticholinergic drugs with rapidly increasing market demand, so it is significant to improve TA production by biotechnological approaches. (biomedcentral.com)
Stramonium2
It was well known as an essential ingredient of magical ointments, potions, and witches' brews, most notably Datura stramonium. (wikipedia.org)
Although most tropane alkaloids cause an anticholinergic syndrome, a case report indicates that the tropane alkaloid-containing medicinal herb Erycibe henri Prain ("Ting Kung Teng") contains a tropane alkaloid that may cause a cholinergic syndrome, as well as kidney, liver, and erythrocyte toxicity. (medscape.com)
Deadly nightshade1
Datura belongs to the classic "witches' weeds", along with deadly nightshade, henbane, and mandrake. (wikipedia.org)
Thorn-apple1
The generic name Datura is taken from Hindi धतूरा dhatūra "thorn-apple", ultimately from Sanskrit धत्तूर dhattūra "white thorn-apple" (referring to Datura metel of Asia). (wikipedia.org)
Species11
Datura is a genus of nine species of highly poisonous, vespertine-flowering plants belonging to the nightshade family (Solanaceae). (wikipedia.org)
Due to their effects and symptoms, Datura species have occasionally been used not only as poisons, but also as hallucinogens by various groups throughout history. (wikipedia.org)
Certain common Datura species have also been used ritualistically as entheogens by some Native American groups. (wikipedia.org)
In the Ayurvedic text Sushruta Samhita, different species of Datura are also referred to as kanaka and unmatta. (wikipedia.org)
The Mexican common name toloache (also spelled tolguacha) derives from the Nahuatl tolohuaxihuitl, meaning "the plant with the nodding head" (in reference to the nodding seed capsules of Datura species belonging to section Dutra of the genus). (wikipedia.org)
Datura species are herbaceous, leafy annuals and short-lived perennials, which can reach up to 2 m in height. (wikipedia.org)
The larvae of some Lepidoptera (butterfly and moth) species, including Hypercompe indecisa, eat some Datura species. (wikipedia.org)
Classifying Datura as to its species is difficult, and the descriptions of new species often are accepted prematurely. (wikipedia.org)
Datura species are native to dry, temperate, and subtropical regions of the Americas, and are distributed mostly in Mexico, which is considered the center of origin of the genus. (wikipedia.org)
Many cultures worldwide add plants with tropane alkaloids (particularly Datura species) to alcoholic beverages to increase intoxication. (medscape.com)
Our data represent the first cross-species analysis of steroidal alkaloid biosynthesis in the genus Veratrum and indicate that the metabolic properties of V. maackii and V. nigrum are broadly conserved despite their distinct alkaloid profiles. (bvsalud.org)
Mandrake1
Warning: Mandrake is highly toxic, especially the leaves and stems but also the root. (enchantedaromatics.com)
Symptoms2
Chinese herbal medicines containing tropane alkaloids have been used to treat asthma, chronic bronchitis, pain, and flu symptoms. (medscape.com)
Symptoms usually occur 30-60 minutes after ingestion and may continue for 24-48 hours because tropane alkaloids delay gastric emptying and absorption. (medscape.com)
Genus2
All parts of the plants are toxic, and the genus has a long history of use for causing delirious states and death. (wikipedia.org)
Liliales) is a genus of perennial herbs known for the production of unique bioactive steroidal alkaloids. (bvsalud.org)
Roots1
We propose that ERF1A, CYP90G1-1 and CYP76AH1 are specifically involved in the key steps of steroidal alkaloid biosynthesis in V. maackii roots. (bvsalud.org)
Compounds1
[ 1 ] The alkaloids represent a very diverse group of medically significant compounds that include well-known drugs such as the opiates. (medscape.com)
Plants2
Toxicity from plants containing tropane alkaloids manifests as classic anticholinergic poisoning. (medscape.com)
These plants can be invasive, toxic, and even lethal. (lotusmagus.com)
Potentially1
We identified 235 differentially expressed unigenes potentially involved in the synthesis of steroidal alkaloids. (bvsalud.org)
Plant2
Alkaloids are plant metabolites that have a nitrogen-containing chemical ring structure, alkali-like chemical reactivity, and pharmacologic activity. (medscape.com)
Isoquinoline alkaloids - Isoquinoline alkaloids 1-Benzyl isoquinoline type: Papaverine: An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. (powershow.com)
Common1
In Africa, a common use of Datura is smoking the leaves to relieve asthma and pulmonary problems. (medscape.com)
Leaves1
It has been observed that while insects may prefer to feed on Datura leaves, other animals such as cows will generally avoid consuming them. (wikipedia.org)
Include1
A subgroup of the alkaloids is the alkaloid amines, which include three major pharmacologic groups: the hallucinogenic alkaloid amines, the stimulant alkaloid amines, and the tropane alkaloids (also called the belladonna alkaloids or bicyclic alkaloids). (medscape.com)