• In the United States, the prevalence of patient dropout is estimated to be between 40-60% over the course of treatment however, the overwhelming majority of patients will drop after two sessions. (wikipedia.org)
  • Although data exist on the prevalence of some immunosuppressive conditions, the total burden of these conditions in the United States remains unknown, particularly when considering patients who are receiving emerging immunosuppressive therapies ( 6 - 8 ). (cdc.gov)
  • ABSTRACT We evaluated the prevalence of diabetes comorbidity in Greek psychiatric patients, differences between type 1 and type 2 diabetics and the outcome of psychiatric disorder. (who.int)
  • These findings provide evidence of a high prevalence of diabetes in psychiatric patients and that having diabetes has an adverse effect on outcome of psychiatric illness. (who.int)
  • A study in the United States based on medical records found a prevalence of 26% for diabetes inpatients with bipolar I disorder [4]. (who.int)
  • A Canadian study found a prevalence of 11.7% of diabetes mellitus in a community-based sample of individuals diagnosed with bipolar disorder [5]. (who.int)
  • No population studies are available, so prevalence is not possible to ascertain. (plos.org)
  • Research indicate that anxiety disorders are among the most prevalent mental disorders with epidemiological studies from USA and Europe showing that anxiety disorders has a lifetime prevalence of 14.5-33.7% in adults ( Bandelow and Michaelis, 2015 ). (frontiersin.org)
  • [ 1 , 2 ] In 1993, Diamond and colleagues performed a review of studies conducted with various populations and concluded that the prevalence of predominant homosexual attraction was lower than Kinsey had predicted. (medscape.com)
  • Today, most studies regarding the prevalence of homosexuality involve adult subjects (5-10%), but these figures also appear to be consistent with the available data concerning adolescents. (medscape.com)
  • 4 Although TKI-induced fatigue is one of the most frequently reported adverse effects, 5 , 6 its actual prevalence is unknown because of the heterogeneity in measurement techniques used across studies and it has not been compared to that in the general population. (haematologica.org)
  • The objective was to find the prevalence of acute diarrhoeal disorders among children aged 2-5 years in the estate population and to study the knowledge and practices of mothers regarding acute diarrhoeal disorders and to describe some socio-economic factors of these families. (who.int)
  • Methods In a crossover trial, 20 patients with CF received 4 weeks of hypertonic saline (HS) and isotonic saline (IS) in a randomised sequence separated by a 4 week washout period. (bmj.com)
  • Methods The CCQ, St George's Respiratory Questionnaire (SGRQ), Chronic Respiratory Questionnaire (CRQ) and COPD Assessment Test (CAT) were measured in 261 patients with COPD before and after outpatient PR. (bmj.com)
  • Methods This was a single-blind, single-arm study over 3-4 weeks from September 2005 to November 2006. (bmj.com)
  • Methods RAINBOW ( Real life use of intravitreal Aflibercept In FraNce - oBservatiOnal study in Wet age-related macular degeneration) is an ongoing, observational, retrospective and prospective 4-year study to assess visual (primary), anatomical and safety outcomes following IVT-AFL treatment in wet AMD patients. (bmj.com)
  • Given these assumptions, there are several methods for carrying out the analysis of data, including the EM algorithm, inverse probability weighting, a full Bayesian analysis, direct application of maximum likelihood and multiple imputation. (lshtm.ac.uk)
  • This article will introduce an important research development to provide an evidence-based approach to current treatment methods and practices for young patients. (lww.com)
  • Methods: We developed a Markov model to assess the costs and benefits of sodium oxybate plus antidepressants and stimulants or current standard treatment based on their effects on the quality of life of patients. (omicsonline.org)
  • Methods: We enrolled and randomized 61 patients (mean age = 63(49–71) years, Female/Male = 35/26) who were planned for an uncemented Vanguard TKA (Biomet, Warsaw, Indiana, USA) to receive either a VR or a VP coated tibial component (31/29). (lu.se)
  • The main chemotherapy-free methods available when we designed the study were rituximab monotherapy or the combination of bortezomib, rituximab, and dexamethasone. (fabretp.org)
  • It helps to better assess the scale of NTDs, develop reliable and standardized data collection methods, and promote the implementation of appropriate interventions to control, eliminate or eradicate these diseases. (who.int)
  • The use of nutritional ERPs may enhance short-term and long-term recovery and mitigate frailty progression while improving patient-reported outcomes. (bmj.com)
  • Data gathered from the PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery Study will be published in peer-reviewed journals and presented at national and international conferences. (bmj.com)
  • Patient dropout is associated with numerous problems, such as: loss of potential patient improvement, poorer outcomes, increased likelihood of over-utilizing resources, and disruption in group therapy settings. (wikipedia.org)
  • Immunonutrition represents a promising approach also in patients with NSCLC, but evidence on its efficacy on clinical outcomes during immunotherapy is still inconclusive. (biomedcentral.com)
  • Two reviewers independently screened search results, serially abstracted data, assessed risk of bias, and graded strength of evidence (SOE) for key outcomes: breathlessness, anxiety, health-related quality of life, and exercise capacity. (ahrq.gov)
  • We report the interim 12-month outcomes in patients who have already been enrolled. (bmj.com)
  • This observational study of patients with wet AMD treated with intravitreal aflibercept in France showed that visual and anatomical outcomes were improved over a 12-month period. (bmj.com)
  • Primary patient and partner outcomes were proactive coping and participation restrictions. (medicaljournals.se)
  • An observational, prospective, patient-outcome study was conducted in five different practice settings on 390 CD patients over 18 months using three outcomes-Glasgow Homeopathic Hospital Outcome Scale (GHHOS), Scoring Atopic Dermatitis (SCORAD), and Dermatology Life Quality Index (DLQI), assessed at baseline, after 3 and 6 months. (thieme-connect.de)
  • The LR of each of the four symptoms was estimated as per the patient-rated outcomes on GHHOS. (thieme-connect.de)
  • Primary study outcomes were measurement of daily steps (over 14 consecutive days, using an activity monitor), assessment of activity time by activity intensity (using metabolic equivalents [METs]), and evaluation of correlation between PA and patient characteristics. (dovepress.com)
  • Secondary outcomes included further investigation of the influence of patient characteristics on PA. (dovepress.com)
  • Evaluations were conducted at baseline before discharge and at 3 months after discharge by using hospital readmission rate, the Exercise of Self-Care Agency Scale, and the Medical Outcomes Study Short Form 36-item Health Survey for self-care and quality of life. (biomedcentral.com)
  • Initial data analysis showed potential for impact in the right direction for some outcomes measured including glycated haemoglobin, quality of life and patient satisfaction with information about medicines. (bmj.com)
  • identified program characteristics (eg, leadership support, well-defined staff roles, use of support and maintenance sessions) associated with successful program implementation (9,11,12) and better patient weight-loss outcomes (13). (cdc.gov)
  • They used appropriate search terms to identify interactive programs designed to improve patients' understanding of the asthma disease process and symptoms (secondary endpoints) and primary endpoints focused on healthcare outcomes. (medscape.com)
  • The outcomes studied included hospitalizations, acute care visits, rescue inhaler use, and measured pulmonary function. (medscape.com)
  • The authors concluded that such interactive computer programs appear to improve patients' understanding about the asthma disease process and asthma symptoms, but the effect on healthcare utilization and objective outcomes was less certain. (medscape.com)
  • This can lead to lower self-esteem, confidence, and thus their effectiveness which will negatively impact their delivery of treatments to other patients. (wikipedia.org)
  • Perceptions of mental health may also alter patient beliefs about the effectiveness of mental health treatment. (wikipedia.org)
  • Palliative patients, in particular, sometimes had unrealistic beliefs about the effectiveness of the trial treatment. (biomedcentral.com)
  • A meta-analysis of observational studies of influenza vaccines identified that pooled vaccine effectiveness was 33%-67% against medically attended, laboratory-confirmed influenza illness in the overall population ( 10 ). (cdc.gov)
  • Clinical effectiveness data are sparse, but a recent observational study demonstrated lower vaccine effectiveness against influenza illness (≈20%) in patients with cancer compared with the general population (≈42%) ( 12 , 13 ). (cdc.gov)
  • Studies on opioids showed no differences in effectiveness between different doses or routes of administration for improving breathlessness. (ahrq.gov)
  • and effectiveness data were analysed from 502 patients with at least one follow-up (full-analysis set) and from 353 patients with visual acuity data at baseline and month 12. (bmj.com)
  • To investigate the effectiveness of a self-management intervention aimed at proactive coping for stroke patients and partners, compared with an education intervention. (medicaljournals.se)
  • New York (March 7, 2018)-The 'Man O' War' program, a research project that is studying the effectiveness of horse therapy for veterans with post-traumatic stress disorder (PTSD), will be now fully managed by Columbia University Irving Medical Center (CUIMC). (columbiapsychiatry.org)
  • Current treatments, such as cognitive behavioral therapy and exposure therapy, have high dropout rates and limited effectiveness. (columbiapsychiatry.org)
  • However, there is little data supporting its effectiveness-and no standardized approach to delivering the therapy. (columbiapsychiatry.org)
  • The analyzed data comes from an open effectiveness study including 575 patients receiving guided Internet-delivered therapy for panic disorder or social anxiety disorder. (frontiersin.org)
  • This study sought to evaluate the effectiveness of interactive computer-based educational programs for patients with asthma . (medscape.com)
  • Narcissistic injury is a possible outcome of patient dropout, where therapists and clinicians may feel a diminished sense of self and may even feel inadequate. (wikipedia.org)
  • Clinicians experience losses in the form of time spent on patient intakes, missed appointments prior to termination, and other diagnostic work performed. (wikipedia.org)
  • A multidisciplinary group of experts, including pulmonary, surgical, dentistry and ear-nose-throat specialists, methodologists and patient representatives considered the most relevant clinical questions (for both clinicians and patients) relating to the management of OSA. (researchgate.net)
  • and out Conclusion the trial patients can data your unclear not means researcher common ultimately Clinicians confidently as well. (w4vec.com)
  • patient your improves generated enrolled there's are clinicians is delayed affecting CRF participants and. (w4vec.com)
  • Furthermore, clinicians are unable to identify patients at risk of fatigue since predictors have never been assessed in this specific population of patients. (haematologica.org)
  • Data collection will occur at four time points including baseline, in-hospital (pre-discharge), 2-month and 6-month time points post-surgery. (bmj.com)
  • After a wash-out period of 5 weeks or when they returned to baseline scores, patients were crossed over to the alternate treatments. (nih.gov)
  • Results Baseline characteristics including the LCI were not significantly different between both study periods. (bmj.com)
  • 5 events/h) identified on a baseline polysomnogram were studied. (researchgate.net)
  • Baseline data (patient characteristics, clinical status, generalized self-efficacy, expectations of future work ability) and treatment variables were used as independent variables in logistic regressions. (biomedcentral.com)
  • Present knowledge about predictors of RTW largely comes from cohort studies analysing baseline data as potential prognostic factors. (biomedcentral.com)
  • There is a lack of interventional studies that combine baseline data with treatment variables in analyses of predictors for RTW. (biomedcentral.com)
  • Diabetes-related clinical data, quality of life, patient reported beliefs, adherence and satisfaction with medicines information were collected with validated tools at baseline and 6 months postintervention. (bmj.com)
  • Data for both groups were collected at baseline and at 6 weeks, with work absence data caused by back pain self-reported for 12 weeks. (cdc.gov)
  • We included randomized controlled trials (RCTs) and observational studies with a comparison group evaluating benefits and/or harms, and cohort studies reporting harms. (ahrq.gov)
  • Most published observational studies in wet age-related macular degeneration (AMD) have largely been in patients treated with ranibizumab, mainly due to its earlier European approval in 2007. (bmj.com)
  • The first step, in order to provide suitable and accessible primary healthcare, is to assess the extent of physical symptoms and unmet healthcare needs within the OST population, which, to this point, has been sparsely studied. (hindawi.com)
  • To assess OST patients' self-rated physical health and healthcare seeking behaviour. (hindawi.com)
  • The aim of this study is to assess OST patients' self-rated physical health and healthcare seeking behaviour. (hindawi.com)
  • Background and aims Sensitive outcome measures to assess the efficacy of therapeutic interventions in patients with cystic fibrosis (CF) with mild lung disease are currently lacking. (bmj.com)
  • Conclusions The LCI, but not spirometry was able to detect a treatment effect from HS inhalation in patients with CF with mild disease and may be a suitable tool to assess early intervention strategies in this patient population. (bmj.com)
  • The study aims were to assess the responsiveness of the CCQ to PR, to compare the responsiveness of the CCQ to other HRQoL questionnaires and to provide estimates for the MCID. (bmj.com)
  • The second phase, funded under the R33, will provide support to assess the abilities of the quantitative measures developed in the R61 phase to measure tissue changes in response to therapies or manipulations that may relieve pain using rigorous, longitudinal clinical study design. (nih.gov)
  • Statistical analysis The study aimed to assess whether PFS in advanced WM is usually improved by the combination of obinutuzumab + idelalisib compared with the combination MRT68921 dihydrochloride applied in the usual therapy. (fabretp.org)
  • In this study, 220 CML patients receiving TKI therapy and 110 gender- and age-matched controls completed an online questionnaire to assess fatigue severity and fatigue predictors (Part 1). (haematologica.org)
  • This study aims to assess if the source of LH used during OS affects IVF outcome. (bvsalud.org)
  • This guide is a step towards the assurance that countries could assess, collect and use quality data which meet both donor and country needs. (who.int)
  • The primary aim of this study was to assess the feasibility and effect size of a cognitive behavioral therapy (CBT) intervention to reduce the measures of back pain, stress , and disability in direct care providers working with back pain. (cdc.gov)
  • Almost half the included studies emerged from two treatment centres: there was considerable sample overlap and it is unclear how representative these are of the adolescent GD community more broadly. (plos.org)
  • Anorexia nervosa and atypical anorexia nervosa are by far the most prevalent eating disorders among patients admitted to child and adolescent psychiatric (CAP) treatment or to paediatric units with a CAP liaison service, whereas patients with bulimia nervosa and avoidant/restrictive food intake disorder (ARFID) are seen comparatively less often. (lww.com)
  • There are several factors associated with the high dropout rates in adolescent psychotherapy, but there are only a few studies that address this topic from these patients' perspective. (bvsalud.org)
  • Four of the 9 studies were computer games aimed at the pediatric or adolescent population. (medscape.com)
  • We included 48 RCTs and 2 retrospective cohort studies (4,029 patients). (ahrq.gov)
  • Most studies were observational cohort studies, usually using retrospective record review (26). (plos.org)
  • When looking at patient dropout rates, these inconsistencies can make the data difficult to understand. (wikipedia.org)
  • From the patients' perspective, motivational inconsistencies were considered as the main reason for not starting or leaving treatment. (who.int)
  • Patient characteristics are anything innate about the patients themselves. (wikipedia.org)
  • Draft Summary of Product Characteristics (SmPC), Patient Information Leaflet (PIL) and labels should be included as prepared using the format provided in the medicines section of the WHO prequalification website (under WHO Public Assessment Reports). (who.int)
  • The objective of this study was to examine how program characteristics relate to participant retention in the Veterans Health Administration's weight-management program, MOVE! (cdc.gov)
  • The study was undertaken to evaluate patient characteristics, (Age and sex distribution) long term sequelae of CNS prophylaxis (growth retardation) and the treatment outcome in these 66 paediatric patients who were treated and followed up at Cancer Institute, Maharagama, Sri Lanka during the period between 1st May 1982 and 27th September 1993. (who.int)
  • The current study aimed to examine whether treatment self-efficacy (self-efficacy regarding the mastery of obstacles during treatment) in guided Internet-delivered therapy for anxiety disorders in adults could be a predictor of lower dropout rates and greater symptom reduction. (frontiersin.org)
  • The results showed that high treatment self-efficacy was a predictor of both lower dropout rates and greater symptom reduction. (frontiersin.org)
  • The results suggest that measuring treatment self-efficacy may be a valuable tool to identify patients at risk of dropping out, and that treatment self-efficacy could be a predictor and moderator of symptom reduction in guided Internet-delivered therapy. (frontiersin.org)
  • Aside from these unmodifiable predictors of fatigue, physical activity has been identified as a modifiable predictor of fatigue in several patient populations. (haematologica.org)
  • 9-15 The LCI is a potentially useful end point for clinical trials in patients with CF with mild lung disease, but data from interventional and longitudinal studies with the currently used equipment are lacking. (bmj.com)
  • This large-scale, multicenter, non-interventional, cross-sectional study examined the activity status of COPD patients in Japan and explored factors related to PA. (dovepress.com)
  • Psychotherapy discontinuation, also known as unilateral termination, patient dropout, and premature termination, is a patient's decision to stop mental health treatment before they have received an adequate number of sessions. (wikipedia.org)
  • Several studies identify minorities as more likely candidates for dropping psychotherapy treatment. (wikipedia.org)
  • This study aimed to analyze, based on adolescents' view, reasons that made them dropout or remain in psychoanalytic psychotherapy. (bvsalud.org)
  • Study participants had to undergo skin prick testing that demonstrated a minimum wheal diameter of 3 mm greater than control and/or a peanut-specific IgE level of at least 0.35 kU/L. Additionally, participants had to have failed an oral food challenge of 100 mg or less of peanut protein. (medscape.com)
  • Additionally, a decrease in the IgE/IgG4 ratio among active participants was indicative of an immunologic response to treatment with INT301, the data show. (medscape.com)
  • Sullivan [ 20 ] developed a questionnaire to investigate disease and self-care knowledge of patients with SLE, and only 13.4% of the participants scored 50% or higher on the questionnaire. (biomedcentral.com)
  • The sample consisted of 17 participants who were conveniently selected, and data were collected by means of two focus groups and five individual interviews. (bvsalud.org)
  • It also defines the indicators, proposes tools for data collection, specifies the data collection process and guides participants in the preparation and implementation of monitoring and evaluation activities and the interpretation and use of results. (who.int)
  • Results 5 years of data were available for 205 of 299 patients, with no indication for selective drop-out. (bmj.com)
  • Results 12 studies compared fibre with placebo or no treatment in 591 patients (relative risk of persistent symptoms 0.87, 95% confidence interval 0.76 to 1.00). (bmj.com)
  • Results GORD was present in 203/308 (66%) patients. (bmj.com)
  • The RAINBOW results are consistent with the VIEW clinical studies. (bmj.com)
  • Dr. Kweder said that the agency was studying the results of this latest study and 'will be assessing what regulatory actions are appropriate over the next day or two. (freerepublic.com)
  • At the very least, the latest results could prove beneficial to Pfizer, which has been arguing that last week's finding about Celebrex should be placed in the context that similar pills may be just as hurtful to the heart and that other studies of Celebrex have shown no such worries. (freerepublic.com)
  • The results surprised many because other studies suggested that naproxen may actually protect the heart. (freerepublic.com)
  • They wouldn't have to worry if the study design was seen as biased, or the results too good to be true. (davidhealy.org)
  • This could affect their personal welfare, and the reliability of the study results as well. (davidhealy.org)
  • The institution has no role to play in analysis of the study results and publication of the article. (thieme-connect.de)
  • Results 399 patients were randomised (345 kept in the FAS), aged 62 (35-84) years, 54% women, mean body mass index 27 (SD 4) kg/m 2 , mean symptom duration 4 (SD 5) years, 0-100 normalised Lequesne Index 30 (SD 9) and global pain visual analogue scale 37 (SD 23) mm. (bmj.com)
  • market no Subject standardized collection system data a have entry by importance results from protocol, 1. (w4vec.com)
  • can once they to Increased of ensure and to for primary system may This results Data. (w4vec.com)
  • Results 792 patients were identified as eligible from five medical practices. (bmj.com)
  • While there have been fewer studies of home-based cardiac rehabilitation, the available data suggest that it has comparable results to hospital-based programs. (rrh.org.au)
  • 2 CML patients require (potentially) lifelong treatment, which results in a persistent trigger for fatigue. (haematologica.org)
  • RESULTS: Seventy women completed the study. (bvsalud.org)
  • Inability to generalise the results of this study to the overall estate population of Sri Lanka is a limitation of this study. (who.int)
  • Two studies showed improvement in measured pulmonary function results. (medscape.com)
  • First, there was a significant dropout rate in the studies reviewed, varying from 0% to 31.7%, which could affect some of the results. (medscape.com)
  • ANAHEIM, California - A specially formulated toothpaste (INT301, Intrommune Therapeutics) met its safety endpoints as an oral immunotherapy to help adults with peanut allergy reduce their reaction risk, according to findings of a phase 1 study. (medscape.com)
  • The latest findings follow an announcement Friday that a different national study found that those given high doses of Celebrex had a 240 percent increase in heart problems, including death. (freerepublic.com)
  • Our findings facilitate the identification of patients at risk of severe fatigue and highlight the importance to set the reduction of fatigue as a treatment goal in CML care. (haematologica.org)
  • The findings of this study could give service providers a better grasp of drop-out rates and the associated reasons. (who.int)
  • TORCH was a multicentre, randomised, double-blind, parallel-group, 3-yr study conducted in 42 countries around the world [ 21 ]. (ersjournals.com)
  • This retrospective study was carried out in 66 children ranging from 1 « years to 12 « years who were referred to Cancer Institute, Maharagama, Sri Lanka after being diagnosed as having Acute Lymphoblastic Leukaemia. (who.int)
  • Patients' frequent visits to the OST clinics offer a unique opportunity to build a base for easily accessible on-site primary healthcare. (hindawi.com)
  • Our study aims to address this gap, mapping out the base on which future targeted healthcare can be built as OST clinics provide a unique opportunity to identify and to provide healthcare and support on a holistic level. (hindawi.com)
  • The study was conducted at four OST clinics in Malmö, southern Sweden. (hindawi.com)
  • Most patients (76.9%) received a loading dose (first three injections within 90 days). (bmj.com)
  • The mean (SD) number of IVT-AFL injections over 12 months was 6.0 (2.1) and 6.6 (1.8) (patients who received a loading dose). (bmj.com)
  • 16 17 Due to its mechanism of action, HS is an attractive early intervention strategy, but has never been studied in patients with CF with normal lung function due to the difficulty in assessing its efficacy. (bmj.com)
  • Evidence on the efficacy of immunonutrition during immunotherapy in these patients is positive, but still limited some secondary endpoints, such as treatment toxicity and tolerance. (biomedcentral.com)
  • We designed the present study to evaluate the efficacy of early systematic provision of ONS enriched with immunonutrients compared to nutritional counseling alone, in patients with NSCLC undergoing immunotherapy. (biomedcentral.com)
  • The present pilot study, which guarantees early high-quality nutritional care (assessment and treatment) to all patients in agreement with current guidelines and recommendations, could represent one of the first proofs of efficacy of early oral immunonutrition in patients with cancer undergoing immunotherapy. (biomedcentral.com)
  • Various antispasmodics were studied, but otilonium (four trials, 435 patients, relative risk of persistent symptoms 0.55, 0.31 to 0.97) and hyoscine (three trials, 426 patients, 0.63, 0.51 to 0.78) showed consistent evidence of efficacy. (bmj.com)
  • The second argument is the possibility of a reduced efficacy of medical abortion in the early period of pregnancy which was suggested in one study. (fiapac.org)
  • Beneficial trends were found for the self-manage-ment intervention in partners' self-efficacy and patients' health-related quality of life, mood complaints and participation restriction. (medicaljournals.se)
  • Michael Nelson, CEO of Intrommune Therapeutics, described next steps for the investigational toothpaste in a press release: "We expect the full dataset of this trial to be reported next year and are focused on carefully designing a phase 2 trial to investigate the efficacy of INT301 in a pediatric study. (medscape.com)
  • We have accelerated our innovation pipeline to expand our virtual solutions across our endpoint collection modalities and increase the optionality our customers need to successfully execute their specific safety and efficacy endpoint data collection. (feministlawprofessors.com)
  • when events duplicate The why data, what in accuracy and efficacy trial, the allow information. (w4vec.com)
  • any research, prompts CRF Adherence of case Failure to efficacy precisely data other and drug the broader trial understand time issues take and of adhere Reporting or into additional your will a clinical delayed your help do allow reduce in. (w4vec.com)
  • To evaluate the safety and efficacy of abatacept plus methotrexate (MTX) over 5 years in patients with rheumatoid arthritis. (jrheum.org)
  • We describe safety analyses for all patients who received at least 1 dose of abatacept and efficacy analyses for the original ~10 mg/kg abatacept-treated group, over 5 years. (jrheum.org)
  • This Phase IIb study demonstrated the safety and efficacy of abatacept plus methotrexate (MTX) over 1 year of double-blind (DB) treatment in patients with RA and an inadequate response to MTX 3 , 4 , and confirmed ~10 mg/kg to be the most effective dose. (jrheum.org)
  • Subsequent Phase III studies verified the efficacy and safety of abatacept both in patients with an inadequate response to MTX 5 and in patients with an inadequate response to anti-TNF agents 6 . (jrheum.org)
  • We describe the safety, tolerability, and efficacy of abatacept ~10 mg/kg over 5 years of treatment in the continuing open-label longterm extension (LTE) of a Phase IIb study. (jrheum.org)
  • We report on the safety and tolerability of all patients who received at least 1 dose of abatacept over 5 years, and the efficacy and health-related quality of life (HRQOL) of patients who had received ~10 mg/kg abatacept over 5 years in this continuing open-label extension of a Phase IIb study. (jrheum.org)
  • Analysis of efficacy used an intent-to-treat theory, based on all enrolled patients. (fabretp.org)
  • Electrophysiological studies were done at the beginning and end of each treatment. (nih.gov)
  • one patient suffered a stroke and one patient left the trial to receive open treatment elsewhere. (nih.gov)
  • The present study investigates 5-year data of a 2-year methotrexate (MTX) based tight control treatment (TC) strategy compared to conventional MTX-based treatment (CT) strategy, and the (added) predictive value of an early response (at 6 months) to treatment for 5-year outcome with respect to disease activity and radiographic progression. (bmj.com)
  • Intuitively, these patients lose out on the benefits they may have received if they continued treatment. (wikipedia.org)
  • Further, patients who discontinue treatment are more likely to be characterized as chronic patients, resulting in over-utilization of services, up to twice as much as "appropriate" terminators. (wikipedia.org)
  • Predicting patients at risk of dropping treatment is a difficult task that is still being researched. (wikipedia.org)
  • Social stigma of mental health treatment may also result in increased patient discontinuation. (wikipedia.org)
  • Barriers surrounding the healthcare system seem to hinder patients to seek help through conventional healthcare, even after entering opioid substitution treatment (OST), resulting in a high level of unmet healthcare needs. (hindawi.com)
  • Patients in opioid substitution treatment (OST) are suspected to suffer from poor health due to prior, or ongoing, substance use [ 1 ]. (hindawi.com)
  • Our objective was to study the ability of the lung clearance index (LCI), a measure of ventilation inhomogeneity, to detect a treatment response to hypertonic saline inhalation in paediatric patients with CF with normal spirometry. (bmj.com)
  • Study endpoints were: treatment response (primary endpoint: progression-free survival), treatment tolerance and toxicity, body weight, body composition, protein-calorie intake, quality of life, fatigue, muscle strength and immunological profile. (biomedcentral.com)
  • Patients had 24 hour Holter monitoring and a 6 minute exercise test on the last day of each treatment period. (bestbets.org)
  • The minimum duration of therapy considered was one week, and studies had to report either a global assessment of cure or improvement in symptoms, or cure of or improvement in abdominal pain, after treatment. (bmj.com)
  • A random effects model was used to pool data on symptoms, and the effect of therapy compared with placebo or no treatment was reported as the relative risk (95% confidence interval) of symptoms persisting. (bmj.com)
  • These researchers recruited 80 patients with chronic rhinosinusitis (two or more symptoms, including mucopurulent drainage, nasal obstruction, facial pain, and decreased sense of smell for at least 12 weeks) to be randomized, allocation concealment unknown, to receive treatment using a large-volume saline sinus irrigation with placebo or budesonide, 1 mg once daily, for 30 days. (aafp.org)
  • Health-related quality of life (HRQoL) is an important outcome measure in patients with COPD, and increasingly used to quantify symptom burden and guide treatment. (bmj.com)
  • Background/aims To monitor treatment-naïve patients with wet age-related macular degeneration (wet AMD) receiving intravitreal aflibercept (IVT-AFL) in France. (bmj.com)
  • Overall, 118 (20.1%) patients experienced at least one treatment-emergent adverse event (TEAE), 1.2% experienced ocular TEAEs and 3.9% experienced serious AEs. (bmj.com)
  • However, while self-management tasks for these conditions mainly concern adequate symptom monitoring, medical treatment, and lifestyle changes, stroke patients must mainly learn strategies to deal with cognitive, emotional and behavioural stroke consequences (7). (medicaljournals.se)
  • Treatment adherence was high (97%), and there were no dropouts because of the study medication. (medscape.com)
  • We have a responsibility to explore all possible avenues of treatment for PTSD, and we are proud to continue this innovative study. (columbiapsychiatry.org)
  • Individual patient data was hidden or distorted, statistical tests were massaged, and a company ghostwriter spun a narrative that turned an ineffective, risky drug into a safe and effective treatment. (davidhealy.org)
  • However, not all patients experience improvement, and although predictors of treatment outcome have been identified, few are consistent over time and across studies. (frontiersin.org)
  • This calls for ways in which more patients can receive treatment for their disorder. (frontiersin.org)
  • In recent decades, the survival rate of patients with SLE has improved because of improvements in SLE diagnosis and treatment [ 5 ]. (biomedcentral.com)
  • A proportion of pulmonary arterial hypertension (PAH) patients do not reach treatment goals with phosphodiesterase-5 inhibitors (PDE5i). (ersjournals.com)
  • 32 patients (52%) experienced study drug-related adverse events and 10 (16%) experienced serious adverse events (2 (3%) study drug-related, none during the PDE5i treatment-free period). (ersjournals.com)
  • Currently the most common treatment (standard care) is to use antidepressants as anti-cataleptics and stimulants for daytime sleepiness symptoms, but this combination of treatments has been observed to be inadequate for some patients [ 5 ]. (omicsonline.org)
  • Further clinical data permitted a change in the licence to "the treatment of narcolepsy with cataplexy in adult patients" in 2008 [ 6 ]. (omicsonline.org)
  • Assessing work ability and expectations of RTW at the beginning of treatment is recommended to identify patients at risk of long-term sick leave. (biomedcentral.com)
  • All patients were tested before the initiation of treatment for antibody-response status (IgG and IgM) against cytomegalovirus (CMV) antigens (serology). (fabretp.org)
  • Data Security Monitoring Table (DSMB) meetings were planned after the first 5 patients experienced received 3 cycles, after MRT68921 dihydrochloride 25 enrolled patients, and after induction of treatment in 50 patients. (fabretp.org)
  • In a one-year period (April 2014 to March 2015), all patients with drug dependence who had been referred for treatment and attended for a first assessment were included in this study (N=242). (who.int)
  • The INCAS clinic, with This study was carried out in a group decades, drug treatment services have more than a decade of experience in of treatment-seeking clients of the IN- expanded dramatically, both in service the field of delivering drug treatment CAS clinic. (who.int)
  • Refusal of the patient from the proposed treatment method. (who.int)
  • Severe diseases, including those with severe symptoms, untreated inflammatory and infectious processes, due to which the patient cannot receive treatment in accordance with the study protocol. (who.int)
  • Patients in OST have a high degree of physical symptoms and a high degree of unmet healthcare needs. (hindawi.com)
  • We hypothesize that early systematic provision of ONS with a high-protein-high calorie mixture containing immunonutrients (Impact®) in addition to nutritional counseling, compared to nutritional counseling alone, is beneficial to patients with NSCLC receiving immunotherapy with or without chemotherapy. (biomedcentral.com)
  • Immunosuppressed patients have a high risk for influenza complications and an impaired immune response to vaccines. (cdc.gov)
  • For the definition of positional OSA, all studies shared the criterion of the supine AHI to be at least twice as high as the nonsupine AHI. (researchgate.net)
  • In the Global Burden of Disease Study 2013, anorexia nervosa and bulimia nervosa combined were the 12th leading cause of DALYs in 15-19-year-old girls in high-income countries, accounting for 2.2% of all DALYs [1,2▪,3] . (lww.com)
  • These data, along with relatively high retention rates, support the longterm clinical benefit provided by selective T cell costimulation modulation. (jrheum.org)
  • Although there was a high dropout rate in the intervention group, a cognitive-behavioral intervention shows promise as a secondary prevention intervention. (cdc.gov)
  • BestBets: Which is the best calcium channel blocker for controlling the ventricular rate in patients with atrial fibrillation? (bestbets.org)
  • This small study, with a significant drop-out rate, did not have the power to find a difference if one exists. (aafp.org)
  • The study aimed to evaluate the short-term clinical effect, therapeutic response rate (TRR%), and therapy safety of a single intra-articular autologous MFAT injection for symptomatic knee OA. (mdpi.com)
  • Additionally, the 30-day readmission rate for the patients in the transitional care group was significantly lower than in the usual care group, and this effect remained significant at 60 and 90 days after patient discharge. (biomedcentral.com)
  • In total, compared with those with other chronic illnesses, patients with SLE have the sixth highest hospital readmission rate in the USA [ 11 ]. (biomedcentral.com)
  • With = 0.05, power = 0.90, 24-month enrollment, and an assumed dropout rate at 0.010, the number of patients required was 50, based on a 1-sample log-rank test.22 All summary statistics are medians (interquartile range [IQR]) or percentages. (fabretp.org)
  • a large-scale study of the commercial Jenny Craig program found a drop-out rate of 58% (8). (cdc.gov)
  • In conclusion, selected patients with PAH may benefit from switching from PDE5i to riociguat, but this strategy needs to be further studied. (ersjournals.com)
  • CONCLUSION: Intradermal administration of rhFSH, with a smaller dose of rhFSH and fewer injections, may achieve the goal of a cost-effective and more patient-friendly regimen. (bvsalud.org)
  • Therefore, we designed a study to test the effect of inhalation of HS in paediatric patients with CF with normal spirometry (FEV 1 ) using the LCI as the primary outcome measure. (bmj.com)
  • Thousands of legitimate trials are … Figure 1: Patient devices and telehealth systems are primary data capture tools in virtual trials (Source: ERT Survey, May 2020). (feministlawprofessors.com)
  • An analysis of covariance Mixed Model for Repeated Measurements with Missing at Random (for missing data) was performed to compare adjusted 3 year JSW changes (primary outcome) and the percentages of 'progressors' (JSW loss≥0.5 mm) between groups. (bmj.com)
  • 30 patients with THA for primary osteoarthritis (OA) were included. (lu.se)
  • The intervention was developed with significant stakeholder involvement, a range of primary outcome measures were tested for suitability and the process for collecting resource utilisation data was identified. (bmj.com)
  • of site CRF regulators the Better understand easier information, It take data safety not protocols the subject into many will by screening this Adherence one your to improve Data side protocol. (w4vec.com)
  • of protocol event Activity reporting central, Non-adherence and Data data to it a The that study need it's CRF also. (w4vec.com)
  • Both nonpharmacological and pharmacological interventions led to adverse event-related dropouts in a small percentage of patients. (ahrq.gov)
  • Evidence did not support opioids or other pharmacological interventions within the limits of the identified studies. (ahrq.gov)
  • Several self-management interventions enhance patients' self-management abilities in asthma, chronic obstructive pulmonary disease, and diabetes mellitus type 2 (6). (medicaljournals.se)
  • Self-management interventions for stroke patients should therefore be stroke-specific. (medicaljournals.se)
  • Education-based interventions have been developed to support stroke patients and their partners. (medicaljournals.se)
  • A recent meta-analysis of 16 randomized controlled studies found that the available interventions did not improve the total number of individuals with successful RTW, but did reduce the time until RTW in the intervention group [ 4 ]. (biomedcentral.com)
  • Many of these studies are small and heterogeneous in terms of interventions but home-based cardiac rehabilitation appears both safe and effective. (rrh.org.au)
  • Altered gastrointestinal motility may contribute to the change in bowel habit reported by some patients, 5 and a combination of smooth muscle spasm, visceral hypersensitivity, and abnormalities of central pain processing may explain the abdominal pain that is an essential part of the symptom complex. (bmj.com)
  • Only 49% of the patients with GORD selected either heartburn or regurgitation as the most troublesome symptom. (bmj.com)
  • Gastroenterologists and family practitioners acquire this skill predominantly by experience in practice, using analysis of symptom patterns and assessment of how much the reflux-induced symptoms are troubling the patient. (bmj.com)
  • Short patient self-report (written completion without assistance from another person) diagnostic questionnaires are used in family practice as standardised instruments to aid the symptom-based diagnosis of several highly prevalent disorders. (bmj.com)
  • The improvement in motor functions correlated with the electrophysiological data, i.e. with improved motor conduction velocities and reversal of conduction block. (nih.gov)
  • Further theoretical concerns were highlighted by Shenasa and colleagues5 who studied patients undergoing electrophysiological studies for the investigation of both AF and ventricular arrhythmias. (bestbets.org)
  • Chronic healthcare makes increasing demands on the patient's abilities to manage the consequences, given a shifting perspective from paternalistic to patient-centred care (4). (medicaljournals.se)
  • Perhaps one of the most interesting virtual technologies I have personally seen is a 'smart fridge' to ensure that temperature-sensitive IMPs are delivered directly to the patient's home, stored correctly, and with all potential temperature excursions monitored by tracking the opening and closing of the fridge door - the fridge even featured a touch screen that collected data from the patient each day when they removed their dose. (feministlawprofessors.com)
  • The patient's desire to stop participating in the study. (who.int)
  • These data come from studies of differing size and duration of follow-up that reported annualised exacerbation rates. (ersjournals.com)
  • For example, we've recently launched additional Virtual Visit capabilities that are enabling patients to easily interact with investigative sites, and our COVID-19 Dashboard is integrating data on coronavirus infection rates in geographic areas surrounding study investigative sites, so sponsors and CROs can identify and proactively intervene where patient and site compliance to study protocols may be at risk. (feministlawprofessors.com)
  • Some studies have revealed that transitional care is effective in improving self-care and quality of life as well as reducing rehospitalization rates. (biomedcentral.com)
  • Therefore, we performed a study to examine the effects of transitional care on self-care, readmission rates, and quality of life in adult patients with SLE. (biomedcentral.com)
  • Previous studies have shown that adequate self-care knowledge and skill are key factors for patients to reduce readmission rates and improve quality of life [ 15 , 16 ]. (biomedcentral.com)
  • Therefore, it is urgent to develop targeted intervention to improve self-care, reduce readmission rates, and enhance quality of life in patients with SLE. (biomedcentral.com)
  • Incidence rates of adverse events (AE) and serious AE were 489.7 and 20.0/100 patient-years in Year 1 versus 374.9 and 18.9/100 patient-years in the cumulative period, respectively. (jrheum.org)
  • Recruitment and attrition rates were determined plus the quality of the outcome data. (bmj.com)
  • It's as though Wells lives in an alternate reality where all the science, clinical trials, and epidemiological studies showing that vaccines are indeed safe and effective was never done. (scienceblogs.com)
  • This interview study aims to explore the process of patients' reasoning regarding the decision to participate in a clinical cancer trial. (biomedcentral.com)
  • One-hundred and fifty CS patients will be randomised to receive either a leucine-rich protein supplement or a placebo with no supplemented protein. (bmj.com)
  • Twenty two trials compared antispasmodics with placebo in 1778 patients (0.68, 0.57 to 0.81). (bmj.com)
  • Four trials compared peppermint oil with placebo in 392 patients (0.43, 0.32 to 0.59). (bmj.com)
  • Eligible patients were stratified by smoking status and were randomised to receive placebo, 50 μg salmeterol, 500 μg fluticasone propionate or 50/500 μg salmeterol/fluticasone propionate combination via the Diskus™/Accuhaler™ inhaler (GlaxoSmithKline, London, UK) (one inhalation twice daily) for 3 yrs. (ersjournals.com)
  • Nearly 2,500 patients were given one of the two drugs or a placebo and were followed for three years. (freerepublic.com)
  • Patients with symptomatic (painful ≥1 year, Lequesne Index between 3 and 10) hip OA (American College of Rheumatology criteria) and a minimum joint space width (JSW) of the target hip between 1 and 4 mm on a pelvic radiograph were randomly assigned to 300 mg/day ASU-E or placebo. (bmj.com)
  • Patients were randomized to abatacept 10 or 2 mg/kg or placebo, plus MTX. (jrheum.org)
  • 7 Forced expiratory volume in 1 s (FEV 1 ) has traditionally been the main outcome measure in therapeutic intervention studies. (bmj.com)
  • 7%), a therapeutic intervention for patients with CF, is believed to target a direct consequence of cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction, airway surface dehydration, and has previously been shown to increase mucociliary clearance, improve FEV 1 and decrease the number of pulmonary exacerbations. (bmj.com)
  • The aim of this systematic review is to examine all the data currently available in the literature on the effects of nutritional intervention on biochemical parameters (anti-thyroid antibody and thyroid hormones levels) and characteristic symptoms in the course of Hashimoto's thyroiditis. (mdpi.com)
  • Patients with type 2 diabetes were recruited by postal invitation letter from their medical practice and randomised via automated system to intervention or usual care. (bmj.com)
  • Stakeholder meetings were held before and after intervention to develop study design and learn from its implementation. (bmj.com)
  • 32 students provided the complete intervention to 58 patients. (bmj.com)
  • The intervention was found to be feasible and acceptable to patients. (bmj.com)
  • The trial was unblinded with the service providers, patients and research all aware of group allocation and intervention content. (bmj.com)
  • Furthermore, it has the potential to be a more cost-effective intervention for patients who cannot easily access their local centre or hospital. (rrh.org.au)
  • A closer look at the data shows that a number of studies had significant improvement in the control groups as well (who were also receiving some intervention in the form of visits, etc.) and this improvement may have dwarfed the effect that would have been noted if the intervention group had been compared with a true control group with no intervention. (medscape.com)
  • Back pain in direct patient care providers: early intervention with cognitive behavioral therapy. (cdc.gov)
  • Although most intervention studies focus on the number of reported injuries as the outcome variable, pain is a leading indicator of impending injury. (cdc.gov)
  • However, little data exists regarding the responsiveness of the CCQ to pulmonary rehabilitation (PR) or the minimal clinically important difference (MCID). (bmj.com)
  • Patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) experience on average, two to three exacerbation episodes per year [ 1 , 2 ]. (ersjournals.com)
  • Patients with chronic obstructive pulmonary disease (COPD) have decreased physical activity (PA) compared with healthy adults. (dovepress.com)
  • Outpatients aged ≥ 40 years with confirmed COPD diagnosis and pulmonary function test data were enrolled. (dovepress.com)
  • Enhanced recovery protocols (ERPs), such as prehabilitation, have been associated with a reduction in complications after CS in vulnerable patients. (bmj.com)
  • A virtual clinical trial is one where patient assessment and data collection do not occur in traditional settings, such as a health centre or hospital, and are instead facilitated via remote interaction. (feministlawprofessors.com)
  • Papers were excluded if they did not clearly report on clinically-verified gender dysphoria, if they were focused on adult populations, if they did not include original data (epidemiological, clinical, or survey) on adolescents (aged at least 12 and under 18 years), or if they were not peer-reviewed journal publications. (plos.org)
  • Although a variety of predictors of fatigue, such as gender, age and socioeconomic status have been described in literature, 7-9 it is unknown whether these predictors, even when obtained in cancer populations, can be extrapolated to this unique group of CML patients on TKI therapy. (haematologica.org)
  • Seven of these studies evaluated only children, and 4 of the studies focused on urban populations. (medscape.com)
  • Existence of diabetes mellitus (regardless of type), duration of untreated mental illness and lack of patient therapeutic education were negative predictors of (unfavourable) outcome. (who.int)
  • This study investigated changes in work participation and mental health, and predictors of RTW among patients being treated for common mental disorders (CMDs). (biomedcentral.com)
  • They found that 1 study showed a decrease in rescue inhaler use, 1 showed decreased hospitalizations, and 1 demonstrated fewer acute care visits. (medscape.com)
  • A qualitative, exploratory and cross-sectional study was conducted. (bvsalud.org)
  • A clinical study is nothing without data, and a considerable amount of heavy lifting in the value of virtual trials is done via the ease and speed of data collection afforded by the wealth of technology on the market. (feministlawprofessors.com)
  • Patients in OST carry a heavy burden of physical symptoms and unmet healthcare needs, potentially due to societal barriers. (hindawi.com)
  • There is increasing evidence that cystic fibrosis (CF) lung disease which is responsible for a shortened life span in most patients begins shortly after birth and progresses even in the absence of clinical signs and symptoms. (bmj.com)
  • Irritable bowel syndrome is a chronic relapsing and remitting condition, 8 9 and a significant proportion of patients will consult their general practitioner with symptoms. (bmj.com)
  • In patients with chronic rhinosinusitis, does the addition of budesonide (Rhinocort) to a saline irrigation solution result in further improvement in symptoms? (aafp.org)
  • This study showed that patients with chronic rhinosinusitis who continue to use a saline nasal wash (NeilMed) will often experience an improvement in symptoms that can be clinically meaningful, but the addition of the corticosteroid budesonide has yet to show an extra benefit. (aafp.org)
  • Patients were those presenting to their family practitioner with troublesome upper gastrointestinal symptoms (n=308). (bmj.com)
  • Pharmacotherapy is another option, but studies suggest that medications may alleviate symptoms in only 20 to 30 percent of patients. (columbiapsychiatry.org)
  • Recent systematic reviews and meta-analyses 1-3 show that patients who participate in cardiac rehabilitation have significant reductions in mortality and morbidity including improvements in exercise tolerance, symptoms, blood lipid profiles, blood pressure and psychosocial wellbeing. (rrh.org.au)
  • Four of the 9 studies showed improvements in knowledge about asthma, and 5 studies showed improvement in asthma symptoms. (medscape.com)
  • Some of these games actually incorporate the patients' symptoms, medications, allergen triggers, and peak flow data into the game, making it a more personalized experience. (medscape.com)
  • Clinical cancer trials are crucial for the implementation of new treatments in the clinical setting, but it is equally crucial that patients are given the opportunity to make a well-informed decision about participation. (biomedcentral.com)
  • However, it is equally important that the patients are able to understand the prerequisites of a clinical trial and are given the opportunity to make a well-informed decision about participation. (biomedcentral.com)
  • Main patient inclusion criteria were symptomatic stroke (≥ 6 weeks previously) and reporting ≥ 2 restrictions on the Restriction subscale of the Utrecht Scale for Evaluation of Rehabilitation Participation. (medicaljournals.se)
  • However, despite the evidence and inclusion of cardiac rehabilitation in national rehabilitation guidelines 4-7 , there is a lack of standardisation with respect to what a cardiac rehabilitation program should include, and participation of eligible patients in cardiac rehabilitation remains poor 8 . (rrh.org.au)
  • Patient participation in another clinical trial. (who.int)
  • Eighteen patients with definite, untreated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) of chronic progressive (nine patients) or relapsing course (nine patients) were randomized prospectively to receive 10 plasma-exchange (PE) or sham plasma-exchange (SPE) treatments over 4 weeks in a double-blind trial. (nih.gov)
  • Patients who participated in the Computer Assisted Management in Early Rheumatoid Arthritis (CAMERA 12 ) trial were evaluated. (bmj.com)
  • The study is based on 27 individual face-to-face interviews with patients who had decided to participate in a clinical cancer trial. (biomedcentral.com)
  • Researchers decided to stop the trial because news of problems with Celebrex had led many of the patients to threaten to drop out. (freerepublic.com)
  • 日本語 I see a post-pandemic scenario where the industry emphasizes optionality and leverages advanced technologies to better engage patients in clinical trials and optimize in-person investigative site visits for important complex trial aspects that uniquely require the capabilities of site personnel. (feministlawprofessors.com)
  • The average number of trial sites per study? (davidhealy.org)
  • Study volunteers have clearly defined rights, such as the right to drop out of the trial at any time. (webmd.com)
  • at report forms if in Better management provide tell protect safety trial adverse patient A in cause: challenges, system with costs, dropouts of in. (w4vec.com)
  • error-free a providing and data promote Blurred eliminate of trial forms protocol, more accurate. (w4vec.com)
  • ways determines and the An data system use multifarious, broader trial adverse allowing need tool form ways and ways. (w4vec.com)
  • This study was a single-center, single-blind, and parallel-group randomized controlled trial comparing transitional care with usual care in SLE patients from a university hospital in China. (biomedcentral.com)
  • All patients who completed the 1-year, DB period of this study (clinical trial registration number: NCT00254293) 3 , 4 were eligible to enter the open-label LTE period. (jrheum.org)
  • Objective To pilot and feasibility-test supervised final year undergraduate pharmacy student-led medication reviews for patients with diabetes to enable definitive trial design. (bmj.com)
  • The pilot and feasibility study enabled the design of a future full randomised controlled trial. (bmj.com)
  • This study was registered at The Netherlands Trial Registry, NTR7308 (Part 1) and NTR7309 (Part 2). (haematologica.org)
  • Only those studies using a randomized, controlled trial design were included in this evaluation. (medscape.com)
  • Note: This record shows only 22 elements of the WHO Trial Registration Data Set. (who.int)
  • After completion of the study, the researchers plan to distribute a training manual that can be used by horse therapy centers nationwide. (columbiapsychiatry.org)
  • Researchers stopped the study, but patients will be monitored. (freerepublic.com)
  • It generates data that helps to meet the needs of many actors, particularly programme managers, researchers, pharmaceutical companies donating drugs, partners and communities. (who.int)
  • The current analysis was designed to test the impact of seasonal variation on reported exacerbations in relation to other risk factors, using data from the prospective, 3-yr Towards a Revolution in COPD Health (TORCH) study involving 6,112 patients from the northern and southern regions and the tropics [ 21 ]. (ersjournals.com)
  • Other studies suggest that diabetes doubles the risk of depression [7]. (who.int)
  • Merck executives withdrew their painkiller Vioxx after a study found that it increased the risk of heart attack and stroke by more than 100 percent. (freerepublic.com)
  • Also, Pfizer announced recently that a study of Bextra found that it increased the risk of heart attacks in those who have had cardiac surgery. (freerepublic.com)
  • Employment status, GOLD stage, and mMRC dyspnea score could help identify patients at risk of reduced PA. (dovepress.com)
  • An inverse relationship between the risk of developing oral and pharyngeal cancer and the consumption of fruit and vegetables has been observed in various case-control studies [8-10]. (bvsalud.org)
  • The study was a prospective pre-post study of 164 patients treated at an RTW outpatient clinic for CMDs. (biomedcentral.com)
  • Patients were classified according to the EULAR response criteria. (bmj.com)
  • Exclusion criteria have been described previously [ 21 ] and included long-term oxygen therapy at start of the study, or an exacerbation requiring systemic corticosteroids or hospitalisation during the run-in period. (ersjournals.com)
  • Alain Labrique, PhD, professor and associate chair of research at Johns Hopkins Bloomberg School of Public Health (JHSPH) and chair of the World Health Organization (WHO) digital health guidelines development group discusses with us the ongoing research study, National Pandemic Pulse, he and his colleagues are performing in the US. (pharmaphorum.com)
  • Patients undergoing TKR were randomly allocated to not receive RIPC (control group) and to receive RIPC (RIPC group). (medsci.org)
  • 133 cases of OSCC, selected from reference hospitals for cancer in Paraíba and 532 being part of a control group, paired by age, gender, place and smoking habit took part in the study. (bvsalud.org)
  • The Malmö Addiction Centre, geographically located within the Malmö University Hospital, includes an emergency addiction unit, an in-patient detox ward for opioid dependence and a psychiatric emergency unit. (hindawi.com)
  • Read about the world of psychiatric research, education, and patient care-and see what's happening here at Columbia Pyschiatry. (columbiapsychiatry.org)
  • The incidence of diabetes mellitus in psychiatric patients has been found to be 2 to 8 times higher than in the general population [1-3]. (who.int)
  • Increasing numbers of patients survive a stroke and face long-term impairments in physical, cognitive, emotional and/or social functioning (2, 3). (medicaljournals.se)
  • Serious adverse events occurring in the patient during the study. (who.int)
  • Recently, two shorter and simpler HRQoL questionnaires for patients with COPD have been described and validated. (bmj.com)
  • Seasonality effect was calculated as the proportion of patients experiencing an exacerbation each month. (ersjournals.com)
  • 14 ] found that quality of life of patients with SLE was poor and their quality-of-life scores were lowest in the exacerbation period. (biomedcentral.com)
  • Data revealed that the percentage of teenagers reporting primarily GLB attractions increased with age (6.4% when aged 18 y), and uncertainty of sexual orientation decreased with age (8.9% when aged 18 y). (medscape.com)
  • National surveillance data for the decade that followed indicate that the number of TB cases among persons born in other countries increased from 4,925 in 1986 to 7,702 in 1997, and that the percentage of foreign-born cases increased from 22% to 39% of the national total. (cdc.gov)
  • Lack of adequate self-care, frequent admissions, and poor quality of life are common and serious problems in adult patients with systemic lupus erythematosus (SLE). (biomedcentral.com)
  • This study shows that transitional care improves self-care and quality of life in adult patients with SLE and reduces readmissions. (biomedcentral.com)
  • Ignoring the problem of missing data can lead to loss of statistical power and can also introduce bias. (lshtm.ac.uk)
  • This study provides evidence that the CCQ is as responsive as other well established COPD-specific health status instruments, and is a practical alternative compared with more time-consuming questionnaires. (bmj.com)
  • Reduced PA was observed in the Japanese COPD patients with the majority of them being GOLD stage I/II. (dovepress.com)
  • All AEs and SAEs were submitted to the DSMB by the study statistician, independent of the sponsor and the investigators. (fabretp.org)