• These cells produce melanin , the substance that gives skin its color. (medlineplus.gov)
  • Skin with too much melanin is called hyperpigmented skin. (medlineplus.gov)
  • Skin with too little melanin is called hypopigmented. (medlineplus.gov)
  • Skin with no melanin at all is called depigmented. (medlineplus.gov)
  • Pale skin areas are due to too little melanin or underactive melanocytes. (medlineplus.gov)
  • Darker areas of skin (or an area that tans more easily) occurs when you have more melanin or overactive melanocytes. (medlineplus.gov)
  • Dark skin is a type of human skin color that is rich in melanin pigments. (wikipedia.org)
  • Humans with dark skin pigmentation have skin naturally rich in melanin (especially eumelanin), and have more melanosomes which provide superior protection against the deleterious effects of ultraviolet radiation. (wikipedia.org)
  • Too much exposure to the sun may also cause the body to produce more melanin, causing pigmentation under the eyes. (webmd.com)
  • We use a proprietary blend of Triphala and 12 radiance- boosters to fade dark spots, and help prevent melanin overproduction. (sachiskin.com)
  • All this, while supporting the skin barrier health and reducing the risk of irritation, which is most often experienced by melanin rich skins. (sachiskin.com)
  • That's typical in countries close the equator, where the dark pigment melanin protects against UV damage from the sun's rays. (wgbh.org)
  • Physiologic pigmentation, also known as racial or ethnic pigmentation, is an increased production of melanin pigment by melanocytes in dark-skinned individuals. (medscape.com)
  • Axéll T, Hedin CA. Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits. (medscape.com)
  • Hedin CA, Axéll T. Oral melanin pigmentation in 467 Thai and Malaysian people with special emphasis on smoker's melanosis. (medscape.com)
  • Smoking status and smoke-related gingival melanin pigmentation in army recruitments. (medscape.com)
  • The four major mechanisms leading to increased oral pigmentation are discussed in detail: physiologic pigmentation, systemic diseases (eg, Peutz-Jeghers syndrome [PJS]), oral mucosal insults (eg, amalgam tattoo), and neoplastic processes (eg, melanoma). (medscape.com)
  • In a study of Thai subjects and Malaysian subjects, nearly all had physiologic pigmentation, but tobacco users had significantly more oral surfaces displaying pigmentation. (medscape.com)
  • Smoker's melanosis is most evident in whites because of a lack of physiologic pigmentation in the oral mucosa of this population, but some dark-skinned individuals who smoke will have more prominent pigmentation in many oral sites. (medscape.com)
  • The bronze color can range from light to dark (in fair-skinned people) with the degree of darkness due to the underlying cause. (medlineplus.gov)
  • Fair-skinned children are more likely to get dark eye circles. (webmd.com)
  • In contrast, cutaneous lesions are linked directly to fair-skinned and blue-eyed persons with a history of blistering sunburns, and the incidence has increased dramatically (approximately 4-6% per year) over the same period. (medscape.com)
  • The other factor to consider in someone who has traditional risk factors-fair-skinned, a variety of nevi-is to look for the mole that looks different . (medscape.com)
  • [ 7 ] The tendency to develop pigmentation appears to be genetically determined, but color intensity might be influenced by smoking, hormones, systemic medications, and physical factors. (medscape.com)
  • Blisters that develop as part of a systemic (bodywide) disease may start in the deeper layers of the skin and cover widespread areas. (msdmanuals.com)
  • They are a mainstay of treating skin disorders. (msdmanuals.com)
  • It is one of the most common reasons people see doctors who specialize in skin disorders (dermatologists). (msdmanuals.com)
  • Post-inflammatory hyperpigmentation occurs following inflammation, commonly found in acneic skin, Pigmentary changes of this nature are much more common in darker-skinned individuals. (dermasweep.com)
  • People with very dark skin are often referred to as "black people", although this usage can be ambiguous in some countries where it is also used to specifically refer to different ethnic groups or populations. (wikipedia.org)
  • The global distribution of generally dark-skinned populations is strongly correlated with the high ultraviolet radiation levels of the regions inhabited by them. (wikipedia.org)
  • Studies into these populations indicates dark skin is not necessarily a retention of the pre-existing high UVR-adapted state of modern humans before the out of Africa migration, but may in fact be a later evolutionary adaptation to tropical rainforest regions. (wikipedia.org)
  • Due to mass migration and increased mobility of people between geographical regions in the recent past, dark-skinned populations today are found all over the world. (wikipedia.org)
  • In the tropics, natural selection favoured dark-skinned human populations as high levels of skin pigmentation protected against the harmful effects of sunlight. (wikipedia.org)
  • Indigenous populations' skin reflectance (the amount of sunlight the skin reflects) and the actual UV radiation in a particular geographic area is highly correlated, which supports this idea. (wikipedia.org)
  • Historically it has been used by anthropologists and scientists as a racial and ethnic classification to describe various dark-skinned populations, as in North Africa, the Middle East, Malaysia, and South Asia. (dictionary.com)
  • By the time modern Homo sapiens evolved, all humans were dark-skinned. (wikipedia.org)
  • The earliest primate ancestors of modern humans most likely had light skin, like our closest modern relative-the chimpanzee. (wikipedia.org)
  • That gene encodes an enzyme that influences pigmentation in mice and humans. (nature.com)
  • Early biopsy of focal pigmentations of undetermined etiology is extremely important in order to detect oral melanomas at an early stage. (medscape.com)
  • Conditions such as melanotic macules , nevi, smoker's melanosis , amalgam and graphite tattoos, racial pigmentation , and vascular blood-related pigments occur with some frequency. (medscape.com)
  • Abnormally dark or light skin is skin that has turned darker or lighter than normal. (medlineplus.gov)
  • Patients with darker skin, however, have a higher prevalencethan those with lighter pigmentation. (scirp.org)
  • Yet even in Senegal, a land of dark hues, some people aspire for lighter tones. (wgbh.org)
  • For example, are there any rashes or skin lesions ? (medlineplus.gov)
  • [ 5 ] This type of pigmentation appears as flat, light-to-dark-brown lesions, which are evenly pigmented and bilaterally symmetrical. (medscape.com)
  • Paired with our targeted SkinFusions, this synergistic treatment tackles stubborn pigmentation to even out and brighten skin. (dermasweep.com)
  • Brighten, refine and improve pigmentation, as well as recover and renew blemished skin with the Reluminate PeelFusion. (dermasweep.com)
  • Formulated after years of research, the Triphala Pigmentation Corrector is clinically proven to brighten the skin appearance by a whole 30.5% in just 28 days -less than a month. (sachiskin.com)
  • Keloid disease is a fibro proliferative skin tumor and occurs after a skin trauma in genetically vulnerable individuals. (scirp.org)
  • Oral pigmentation is a relatively common condition that may involve any portion of the oral cavity. (medscape.com)
  • Patients with oral melanoma often recall having a previous pigmentation in the same area months to years before the melanoma diagnosis, and the condition may even have elicited a prior comment from physicians or dentists. (medscape.com)
  • Any oral site may be involved, and the degree of pigmentation and oral involvement vary among affected individuals. (medscape.com)
  • Oral pigmentations may range from light brown to blue-black (see the image below), red, or purple. (medscape.com)
  • Patients with oral malignant melanoma often recall having an existing oral pigmentation months to years before diagnosis, and the condition may even have elicited prior comment from examining physicians and dentists (or healthcare providers, when considering the auxiliaries). (medscape.com)
  • Fungi usually live in moist areas of the body where skin surfaces meet: between the toes, in the genital area, and under the breasts. (msdmanuals.com)
  • Brown as a noun and adjective to describe people with a brownish skin color is often perceived as insulting. (dictionary.com)
  • Dans le cadre de la présente étude transversale menée à Téhéran (République islamique d'Iran), dans un pays où la prévalence du déficit en vitamine D est élevée, nous avons mesuré cette prévalence chez 90 patients souffrant d'un diabète de type 2 et 90 sujets en bonne santé. (who.int)
  • 50 nmol/L) et de l'insuffisance en vitamine D (50-75 nmol/L) était respectivement de 59,0 % et de 27,0 % chez les patients diabétiques, contre 47,0 % et 24,0 % chez les sujets en bonne santé. (who.int)
  • Dark circles under the eyes are common in adults but can also appear in children. (webmd.com)
  • Acne is a common skin condition causing pimples and other abnormalities on the face and upper torso. (msdmanuals.com)
  • Botanicals- we've blended botanicals, including Silymarin, all to help restore skin tone, control inflammation, minimise UV induced sun damage, and soothe redness, all while balancing blemish prone skins. (sachiskin.com)
  • I suffer from post acne marks with every breakout, regardless of whether or not I pick at my skin or leave it alone. (sachiskin.com)
  • Since using the Triphala Pigmentation Corrector, my post acne marks are less pigmented and fade significantly faster. (sachiskin.com)
  • Dark-skinned people who live in high latitudes with mild sunlight are at an increased risk-especially in the winter-of vitamin D deficiency. (wikipedia.org)
  • Due to natural selection, people who lived in areas of intense sunlight developed dark skin colouration to protect against ultraviolet (UV) light, mainly to protect their body from folate depletion. (wikipedia.org)
  • Yet people from the region have the darkest skin pigmentation outside Africa. (nature.com)
  • From his research, he's found that people from Senegal and the islands of Micronesia have some of the darkest skin tones in the world. (wgbh.org)
  • I saw myself among a lot of light-skinned people and I thought, "Wow, my skin is amazing. (wgbh.org)
  • Yet some people in Senegal use skin-lightening products. (wgbh.org)
  • This is due, in part, to the exposure of blood vessels under the thin skin of the eyes. (webmd.com)
  • Genetic evidence also supports this notion, demonstrating that around 1.2 million years ago there was a strong evolutionary pressure which acted on the development of dark skin pigmentation in early members of the genus Homo. (wikipedia.org)
  • The exclusive combination of age reversing growth factors, nourishing proteins, repairing peptides, ceramides and protective anti-oxidants aid in renewing skin from the inside out. (dermasweep.com)
  • Rarely, when a high concentration of a medication is needed at the affected area, a doctor injects the medication just under the skin (intradermal injection). (msdmanuals.com)
  • Note the small area of darker pigmentation. (medscape.com)
  • Over-the-counter and prescription creams are available for lightening the skin. (medlineplus.gov)
  • Your provider may recommend creams, ointments, surgery, or phototherapy, depending on the type of skin condition you have. (medlineplus.gov)
  • Bleaching creams can help lighten dark areas of skin. (medlineplus.gov)
  • and told me to try skin-lightening creams. (wgbh.org)
  • The evolution of dark skin is believed to have begun around 1.2 million years ago, in light-skinned early hominid species after they moved from the equatorial rainforest to the sunny savannas. (wikipedia.org)
  • a person whose skin has a light- or dark-brown pigmentation. (dictionary.com)
  • Pulse oximeters can measure blood oxygen saturation levels by sending light through the skin painlessly. (medlineplus.gov)
  • Pulse oximeters clip onto a fingertip and send beams of red and infrared light through tissues such as the nail, skin, and blood. (medlineplus.gov)
  • Corns are hard cone-shaped bumps of skin commonly found on the top surface of the smaller toes, particularly over a joint. (msdmanuals.com)
  • The outcome is firmer, smoother, brighter, luminous skin with an amazingly even tone and texture. (dermasweep.com)
  • Asides my PIH fading, my skin overall looks brighter & healthier. (sachiskin.com)
  • RÉSUMÉ Une relation inverse a été démontrée entre le déficit en vitamine D et le diabète de type 2. (who.int)
  • La prévalence du déficit en vitamine D chez les hommes atteints d'un diabète de type 2 était de 42,7 %, contre 22,2 % chez les hommes en bonne santé. (who.int)
  • When bacterial skin infections do occur, they can range in size from a tiny spot to the entire body surface. (msdmanuals.com)
  • Blisters most commonly form in response to a specific injury, such as a burn or irritation, and usually involve only the topmost layers of skin. (msdmanuals.com)
  • Some skin color changes may return to normal without treatment. (medlineplus.gov)
  • This is especially true if you have no other apparent symptoms other than the appearance of the dark skin color beneath the eyes. (webmd.com)
  • Changes may be visible around their eyes, where a dark color forms. (webmd.com)
  • a dark tertiary color with a yellowish or reddish hue. (dictionary.com)
  • Coronary artery or heart disease is noticeable with skin color and texture changes [skin could become shiny, tight and discolored] thereby helping your doctor diagnose the cause. (aawconline.org)
  • We talked to her about skin color, beauty norms and her mission to empower girls. (wgbh.org)
  • When did you first realize that your skin color was special? (wgbh.org)
  • In my family, only my brother has a similar skin color. (wgbh.org)
  • Did you face any pressure to change your skin color? (wgbh.org)
  • Morrison's last novel adopts the author's quintessential themes of beauty, American blackness versus whiteness, slavery and the ghosts of communal and individual traumas, inholding the lasting injury of rejection for having a skin color which is too dark, hair that is too kinky. (lu.se)
  • I wanted to try it at the time because I felt a little embarrassed being dark, but my sister told me not to, because she said my skin was unique and beautiful. (wgbh.org)
  • The result is uneven skin tone, brown blotchy areas, dark spots and age spots. (dermasweep.com)
  • They're here to address dark spots and hyperpigmentation, and also to provide antioxidant protection. (sachiskin.com)
  • Microalgae- encapsulated in a liposome delivery system, these microalgae actives effectively fade dark spots, and even skin tone. (sachiskin.com)
  • As hominids gradually lost their fur between 1.2 and 4 million years ago, to allow for better cooling through sweating, their naked and lightly-pigmented skin was exposed to sunlight. (wikipedia.org)
  • The loss of body hair led to the development of dark skin pigmentation, which acted as a mechanism of natural selection against folate (vitamin B9) depletion, and to a lesser extent, DNA damage. (wikipedia.org)
  • Insufficient vitamin A may lead to the formation of dark circles under your child's eyes. (webmd.com)
  • the relationship between folate breakdown induced by ultraviolet radiation and reduced fitness as a failure of normal embryogenesis and spermatogenesis led to the selection of dark skin pigmentation. (wikipedia.org)
  • Evolutionary pigmentation of the skin was caused by ultraviolet radiation of the sun. (wikipedia.org)
  • Hair follicles are present everywhere on the skin except the lips, palms of the hands, and soles of the feet. (msdmanuals.com)
  • If you believe you have Melasma, we recommend seeing your trained medical skin care professional for a customized DermaSweep treatment plan. (dermasweep.com)
  • Our exclusive combination of alpha-hydroxy acids and botanical ingredients combined with Trichlorecetic Acid (TCA) aids in brightening and enhancing skin clarity and evening out tone and texture. (dermasweep.com)
  • According to a 2002 study in the West African Journal of Medicine , the latest data, 52 to 67 percent of the Senegalese population used skin lightening products on their skin. (wgbh.org)
  • A study of Turkish Army recruits revealed gingival pigmentation in 27.5% of smokers and 8.6% of those who never smoked. (medscape.com)
  • If you have dark circles under your eyes , there is a high probability that your child will get them. (webmd.com)
  • We have taken a multi-pathway approach to skin-brightening which accounts for ALL skin tones in just 1 bottle. (sachiskin.com)
  • This product is for everyone and suitable for all skins and tones, and was formulated to account for highly-melanated and darker skins, which are also more prone to sensitivity. (sachiskin.com)
  • In addition to being effective in fading darkness and hyperpigmentation across tones, it also was made to minimise irritation, making it very suitable for sensitive skins. (sachiskin.com)
  • Calluses are broader, flat thickenings of the skin usually located on the palms or soles. (msdmanuals.com)
  • Einstein was handsome-dark hair, moustache, soulful brown eyes. (dictionary.com)
  • [ 8 ] In this particular site, the pigmentation appears as a well-demarcated, ribbonlike, dark-brown band that usually spares the marginal gingiva (see image below). (medscape.com)