• progression
  • This study evaluates the impact of irbesartan (an AII-RB which acts similar to an ACEinh) and pravastatin on the clinical progression of chronic rejection and on the expression of TGF-beta, PDGF, and connective tissue genes in the chronically rejecting kidney. (clinicaltrials.gov)
  • occurs
  • The Diagnostic and Statistical Manual of Mental Disorders IV says alcohol abuse occurs when an individual continues drinking despite the obvious problems that come with chronic drinking. (michaelshouse.com)
  • If a major stress such as illness or surgery occurs, the kidneys may fail, sending the blood test values up quickly. (vcahospitals.com)
  • This disease can be either acute, meaning it occurs suddenly, or chronic, meaning it is ongoing and eventually ends in kidney failure. (wikipedia.org)
  • In some cases, loin pain-haematuria syndrome occurs after a bladder infection with involvement of the kidney. (wikipedia.org)
  • erythropoietin
  • Iron- Kidney damage results in inability of the kidney to produce erythropoietin, which stimulates red blood cell production. (wikipedia.org)
  • As the kidneys fail, they produce less erythropoietin, resulting in decreased production of red blood cells to replace the natural breakdown of old red blood cells. (wikipedia.org)
  • fail
  • When kidneys fail to filter properly, waste accumulates in the blood and the body, a condition called azotemia. (wikipedia.org)
  • tissue
  • Renal biopsies of patients undergoing chronic rejection show greater expression of profibrotic cytokines, including TGF-beta and PDGF, than normal kidney tissue. (clinicaltrials.gov)
  • Since kidney tissue cannot regenerate if destroyed, the kidneys have a large amount of spare capacity to perform their various functions. (vcahospitals.com)
  • After approximately 2/3 of the kidney tissue is destroyed, there is a rapid rise in waste products in the bloodstream and an apparent sudden onset of severe disease. (vcahospitals.com)
  • progresses
  • Colonization of the gastric mucosa with Helicobacter pylori results in the development of chronic gastritis in infected individuals, and in a subset of patients chronic gastritis progresses to complications (e.g., ulcer disease, stomach cancers, some distinct extragastric disorders). (wikipedia.org)
  • medication
  • It may also be used to describe kidney injury from any single analgesic medication. (wikipedia.org)
  • maintain the medication to treat other conditions or help support the kidneys by stopping all but absolutely essential medications. (medhelp.org)
  • Kidney transplantation involves surgically placing a kidney from someone else and then taking immunosuppressant medication to prevent rejection. (wikipedia.org)
  • Blood
  • 13 In Zucker rats, pyridoxamine lowered levels of cholesterol and triglycerides, inhibited AGE formation, and protected against kidney and blood vessel damage. (lifeextension.com)
  • They appear to result from decreased blood flow to the kidney, rapid consumption of antioxidants, and subsequent oxidative damage to the kidney. (wikipedia.org)
  • Proper kidney function depends upon adequate blood flow to the kidney. (wikipedia.org)
  • Kidney blood flow is a complex, tightly regulated process that relies on a number of hormones and other small molecules, such as prostaglandins. (wikipedia.org)
  • Under normal circumstances, prostaglandin E2 (PGE2) produced by the kidney is necessary to support adequate blood flow to the kidney. (wikipedia.org)
  • In the kidney, this inhibition results in decreased PGE2 concentration causing a reduction in blood flow. (wikipedia.org)
  • Because blood flow to the kidney first reaches the renal cortex (outside) and then the renal medulla (inside), the deeper structures of the kidney are most sensitive to decreased blood flow. (wikipedia.org)
  • They did blood work and found her kidney levels were really high and the vet does not like it. (medhelp.org)
  • As the nerves of the legs become damaged due to the continuously high blood glucose levels, symptoms like burning and pain starts to arise. (healthhype.com)
  • Tests to measure the blood levels of other substances such as albumin, globulin, potassium, sodium, phosphorus and calcium, as well as the red and white blood cell counts are important in order to determine the extent of failure and the best course of treatment. (vcahospitals.com)
  • When healthy, the kidneys are responsible for the continuous filtration of blood in order to maintain fluid, electrolyte, and organic solute balance in the body. (wikipedia.org)
  • In addition to the inability to filter blood, renal failure results in the body's inability to make some vitamins and minerals (example: vitamin D), as well as difficulty excreting excessive amounts of certain vitamins and minerals (example: phosphorus). (wikipedia.org)
  • When the kidneys are damaged, they aren't able to remove excessive phosphorus, causing it to build up in blood. (wikipedia.org)
  • Your doctor may prescribe a phosphate binder that is taken with meals to help remove excess phosphorus Sodium: In patients with renal failure, sodium can cause excessive fluid retention, which can lead to elevated blood pressure, edema, heart failure, and shortness of breath. (wikipedia.org)
  • A confirmation of kidney failure is obtained by performing a blood test which measures the concentration of creatinine and urea. (wikipedia.org)
  • Like AKI, AoCRF can be difficult to distinguish from chronic kidney disease if the patient has not been monitored by a physician and no baseline (i.e., past) blood work is available for comparison. (wikipedia.org)
  • Hypertensive kidney disease is a medical condition referring to damage to the kidney due to chronic high blood pressure. (wikipedia.org)
  • Risk factors for HN include poorly controlled moderate to high blood pressure, older age, other kidney disorders. (wikipedia.org)
  • High blood pressure in the long term can damage the endothelium, commonly known as the blood vessel lining. (wikipedia.org)
  • Researchers have hypothesized that the syndrome may be due to blood vessel diseases of the kidney, spasms of the kidney vessels, or other bleeding disorders (coagulopathy). (wikipedia.org)
  • Angiogram tests to look at the blood vessels in the kidney may show abnormal blood flow, perhaps causing a cramp like pain. (wikipedia.org)
  • creatinine
  • Her Creatinine puts her in stage 3 kidney failure (Stage 4 being that last stage). (medhelp.org)
  • The acute part of AoCRF may be reversible, and the goal of treatment, as with AKI, is to return the patient to baseline kidney function, typically measured by serum creatinine. (wikipedia.org)
  • normally
  • Vitamin D- Normally, the kidney changes vitamin D into its active form, vitamin D3, which helps you absorb calcium. (wikipedia.org)
  • secretion
  • This antibiotic stands in sharp contrast to various other cephalosporins and to the structurally related penicillins in undergoing little or no net secretion by the mammalian kidney. (wikipedia.org)