Cell ProliferationCell DivisionCytotoxicity, ImmunologicCell Line, TumorCells, CulturedCell SurvivalApoptosisSignal TransductionCell CycleAntibody-Dependent Cell CytotoxicityCell LineCell DifferentiationTumor Cells, CulturedCytotoxicity Tests, ImmunologicBromodeoxyuridineRNA, MessengerLymphocyte ActivationBlotting, WesternDose-Response Relationship, DrugCell MovementMice, Inbred C57BLImmunohistochemistryFlow CytometryAntineoplastic AgentsPhosphorylationReverse Transcriptase Polymerase Chain ReactionProliferating Cell Nuclear AntigenRNA, Small InterferingGene Expression Regulation, NeoplasticT-LymphocytesTransfectionDown-RegulationKi-67 AntigenTime FactorsEpithelial CellsCell Growth ProcessesMice, NudeMice, Inbred BALB CFibroblastsGene Expression RegulationMice, KnockoutThymidineGene ExpressionUp-RegulationKiller Cells, NaturalCyclin D1Drug SynergismStem CellsMice, TransgenicDNADrug Screening Assays, AntitumorMolecular Sequence DataEnzyme InhibitorsRNA InterferenceCell DeathCell CountProto-Oncogene Proteins c-aktEnzyme ActivationTranscription FactorsInterleukin-2Muscle, Smooth, VascularCyclin-Dependent Kinase Inhibitor p27Antibodies, MonoclonalCell Transformation, NeoplasticRecombinant ProteinsGrowth InhibitorsBreast NeoplasmsRats, Sprague-DawleyCell Cycle ProteinsDNA-Binding ProteinsMutationHyperplasiaBase SequenceExtracellular Signal-Regulated MAP KinasesGene Knockdown TechniquesProto-Oncogene ProteinsPhenotypeCyclin-Dependent Kinase Inhibitor p21NeoplasmsCell AdhesionMitogensXenograft Model Antitumor AssaysProtein-Serine-Threonine KinasesLymphocytesProto-Oncogene Proteins c-mycMyocytes, Smooth MuscleModels, BiologicalDisease Models, AnimalTumor Suppressor Protein p53MAP Kinase Signaling SystemG1 PhaseMitogen-Activated Protein Kinase 3Antigens, CDNeoplasm ProteinsColonic NeoplasmsTetrazolium SaltsGene Expression Regulation, DevelopmentalCytotoxinsNuclear ProteinsMitogen-Activated Protein Kinase 1