Many chemotherapy drugs used to treat cancer are cytotoxic at very low doses. (cdc.gov)
Antineoplastic1
4. Pharmaceuticals used to destroy cancer cells are called anticancer, chemotherapeutic, antineoplastic, or cytotoxic 5. (studylib.net)
Antibodies2
This application covers novel compositions and uses of cytotoxic radioisotopes attached to antibodies that bind to uPAR, thereby creating precision targeted radiotherapeutics for the treatment of severe COVID-19 and other respiratory diseases. (stockwinners.com)
or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)
Molecules1
Upon the stage of tumorigenesis, down-regulation of the major histocompatibility complex class-I (MHC-I) molecules and also the overexpression of the stress-induced ligands on the surface of malignant cells to avoid recognition by cytotoxic T-lymphocytes (CTLs), make them more sensitive to NK cell-mediated death. (biomedcentral.com)
Inflammation2
1,2 Sustained inflammation, hepatocyte necrosis and regeneration, and fibrotic deposition lead to development of cirrhosis. (ajmc.com)
Allgemein cytotoxic the fledgling inflammation has developmentally difficult of a bridge. (tassenkuchenblog.de)
Esco2
The Esco Cytoculture® Lead-Shielded Class II Biosafety Cabinet is designed for radiopharmaceutical industry usage and protects the operator during work involving radioisotopes. (escolifesciences.eu)
Esco Pharma provides specialist services, equipment packages, and process solutions from our core platforms products leading to improved operator protection, reduction of cross contamination, and more efficient processing, thereby directly and indirectly advancing occupational health and human healthcare. (escopharma.com)
Dose1
To achieve the cytotoxic effect necessary to destroy tumour cells, radioactive dose administered is higher compared to diagnostic imaging. (qtinstruments.com)
Metabolism1
In the case of carbon disulphide, gastrointestinal involvement is attributed to the specific neurotropic action of this substance on the intramural plexus whilst liver damage seems to be more due to the solvent's cytotoxic action, which produces changes in lipoprotein metabolism. (cloudaccess.net)
Cells7
This is due to its useful characteristics: in its decay, it kills cancer cells, having high cytotoxic potency within a very short range (limited to few cancerous cells while sparing surrounding healthy tissues). (iba-radiopharmasolutions.com)
During a viral infection, non-customized (naïve) CD8+ T cells become activated and cytotoxic, seeking out and killing infected cells. (nootropicsnewshubb.com)
There has been a growing interest in studying the critical role of CD8+ T cells in immune response and memory," said Negar Omidvari, the study's lead author. (nootropicsnewshubb.com)
As these drugs cause damage to cells they are termed cytotoxic . (wikidoc.org)
This stress condition can also lead to the attraction of immune cells, notably antigen presenting cells (APCs) (i.e. immature dendritic cells), natural killer cells (NK cells), and cytotoxic T-cells to the site of infection [ 5 , 6 ]. (biomedcentral.com)
Results of this study suggest that STAT3- mediated upregulation of CD44 leads to the gain of cancer stem cell phenotype of PEITC-treated SNU449 cells. (fabad.org.tr)
Endogenous biomolecules (such as lactate dehydrogenase) or previously added exogenous labels (such as the radioisotope 51Cr) that leak into the media are then measured as an indirect readout of the damage caused by effector cells. (technologynetworks.com)
Therapeutic1
Several molecular alterations found in carcinoid tumors might act as molecular targets leading to development of new therapeutic options. (springeropen.com)
Laboratories1
However, workers who handle radioactive materials, such as radioisotopes in health care and laboratories, or radioactive waste, need to take precautions to reduce exposure. (cdc.gov)
Therapy1
Targeted Radioisotope Therapy (TRT) is known as a radiotherapy using cytotoxic radioisotopes which are administered orally or intravenously in a patient and accumulate in a targeted organ or a tumor. (edu.kz)
Reduction1
Improved tolerance of therapies for advanced HCC may lead to reduction in treatment discontinuation and contribute to better patient outcomes. (ajmc.com)
Action1
Pre-Kindergarten As led on the CDC download the next twenty five years: affirmative action in higher education in, the management conversations admitted never had to exist assumed as Contemporary i, nor was they taken to ensure the positive Clostridium of Lyme program. (thelambsivy.com)
System1
Dysregulation or imbalances of the histamine system can be a leading contributor to a variety of disease states and symptoms, many of which can be debilitating or life-disruptive. (justia.com)
Patient2
dantrolene for malignant hyperthermia.Its specific heat reflects this composition.NEW YORK NY Lead investigator for the Platelet Inhibition and Patient Outcomes PLATO trial of ticagrelor AstraZeneca says that negative press surrounding the trial is slowing the uptake of a guidelinerecommended antiplatelet drug in the US and depriving patients of the proven clinical benefits.b.The study results support current guidelines for maternal diets.It often does not require immediate treatment. (sen-e.ru)
Dynamic total-body PET involves injecting a very small amount of a radioisotope tracer into the patient, followed by continuous imaging over a period of time, which creates a movie showing the tracer's kinetics (distribution over time) within the body. (nootropicsnewshubb.com)
Agents1
20] Nonresponders are given other cytotoxic agents, such as paclitaxel. (medscape.com)
Research1
Goldblum leads the Bay Area Neutron Group, a research team focused on neutron detection for nuclear security applications, and founded and directs the Nuclear Policy Working Group, an interdisciplinary team of scholars developing policy solutions to strengthen global nuclear security. (berkeley.edu)
Treatment1
Monopar Therapeutics ( MNPR ) and NorthStar Medical Radioisotopes announced that a provisional patent application entitled "Precision Radioimmunotherapeutic Targeting of the Urokinase Plasminogen Activator Receptor for Treatment of Severe COVID-19 Disease" has been filed with the U.S. Patent and Trademark Office. (stockwinners.com)
Patients1
This has led to much controversy over fluid resuscitation in injured patients. (medicosecuador.com)
Life1
Sometimes, a cytokine storm may be severe or life threatening and lead to multiple organ failure. (stockwinners.com)
Provide1
Radioisotope Dispensing Isolator is designed to provide safe, controlled, and sterile environment for elution and dispensing of radiopharmaceuticals. (escolifesciences.co.id)