• vesicle
  • Macropinocytosis, which usually occurs from highly ruffled regions of the plasma membrane, is the invagination of the cell membrane to form a pocket, which then pinches off into the cell to form a vesicle (0.5-5 µm in diameter) filled with a large volume of extracellular fluid and molecules within it (equivalent to ~100 CCVs). (wikipedia.org)
  • The system is defined more accurately as the set of membranes that form a single functional and developmental unit, either being connected directly, or exchanging material through vesicle transport. (wikipedia.org)
  • A vesicle is a relatively small, membrane-enclosed sac that stores or transports substances. (wikipedia.org)
  • mannose
  • Therefore, Neufeld suggested that I-cell disease was caused by a deficiency in the enzymes that add a specific mannose 6-phosphate tag onto lysosomal enzymes so they can be targeted to the lysosome. (wikipedia.org)
  • Once the enzyme has dissociated from the mannose 6-phosphate receptor, it is translocated from the endosome to the lysosome where the phosphate tag is removed from the enzyme. (wikipedia.org)
  • cells
  • Lysosomes are cell organelles found in most animal cells. (wikipedia.org)
  • Epithelial cells are eukaryotic cells i.e. they have a distinct nucleus and possess membrane-bound organelles. (getrevising.co.uk)
  • Endocytosis and its counterpart, exocytosis, are used by all cells because most chemical substances important to them are large polar molecules that cannot pass through the hydrophobic plasma or cell membrane by passive means. (wikipedia.org)
  • They can constitute up to a third of the plasma membrane area of the cells of some tissues, being especially abundant in smooth muscle, type I pneumocytes, fibroblasts, adipocytes, and endothelial cells. (wikipedia.org)
  • Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). (uniprot.org)
  • Although the particular oligosaccharide modifications are quite different in animal, plant, and fungal cells, the Golgi apparatus always functions as a "carbohydrate factory. (thefreedictionary.com)
  • Membranes also occur inside the cells. (studyadda.com)
  • Plasma membrane of two adjacent cells are fused at a series of points with a network of ridges or sealing strands. (studyadda.com)
  • It is found in follicular cells of ovary of birds and have triple unit membrane. (studyadda.com)
  • Evidence is examined which suggests that the cell membrane is uniquely and ideally fit for its role of bounding the cell's contents and conferring on the cells of higher organisms the ability to move and adhere selectively to one another. (evolutiondeceit.com)
  • Cell membranes are vitally important in holding cells together to form tissue in multi-celled organisms. (evolutiondeceit.com)
  • The fact that such an important security system is performed by the membranes in trillions of cells is an example of Allah's compassion for human beings. (evolutiondeceit.com)
  • The first proposal that the membranes within cells form a single system that exchanges material between its components was by Morré and Mollenhauer in 1974. (wikipedia.org)
  • These membranes are flat sheets that form a continuous barrier around all cells. (wikipedia.org)
  • Phospholipids with certain head groups can alter the surface chemistry of a bilayer and can, for example, serve as signals as well as "anchors" for other molecules in the membranes of cells. (wikipedia.org)
  • Mitochondria
  • They will therefore have a large surface area provided by the microvilli and due to the need for active transport across their cell membranes they will contain a large number of mitochondria providing them with ATP. (biologyguide.net)
  • Importantly, the endomembrane system does not include the membranes of chloroplasts or mitochondria, but might have evolved from the latter (see below: Evolution). (wikipedia.org)
  • secretory
  • This targeting away from the secretory pathway is achieved by the presence of a specific sorting signal, an acidic cluster/dileucine motif, in the cytoplasmic tails of the MPRs. (wikipedia.org)
  • bacterial
  • One common example of such a modification in nature is the lipopolysaccharide coat on a bacterial outer membrane, which helps retain a water layer around the bacterium to prevent dehydration. (wikipedia.org)
  • residues
  • The C-type CRDs are each separated by linker regions of 10-20 amino acids containing a number of proline residues, whose cyclic side chain is fairly rigid and favours a conformation in which the N-terminal cysteine-rich domain is extended as far away from the plasma membrane as possible. (wikipedia.org)
  • receptor
  • The extracellular portion of the receptor is composed of 8 consecutive C-type carbohydrate recognition domains (CRDs) closest to the plasma membrane, followed by a single fibronectin type II repeat domain and an N-terminal cysteine-rich domain. (wikipedia.org)
  • gangliosides
  • While sialic acid exists in free form, or as a part of relatively small heterosaccharide molecules, the major portion of naturally occurring sialic acid is present as a constituent of either glycoproteins or gangliosides. (springer.com)