• vesicle
  • Macropinocytosis, which usually occurs from highly ruffled regions of the plasma membrane, is the invagination of the cell membrane to form a pocket, which then pinches off into the cell to form a vesicle (0.5-5 µm in diameter) filled with a large volume of extracellular fluid and molecules within it (equivalent to ~100 CCVs). (wikipedia.org)
  • The system is defined more accurately as the set of membranes that form a single functional and developmental unit, either being connected directly, or exchanging material through vesicle transport. (wikipedia.org)
  • A vesicle is a relatively small, membrane-enclosed sac that stores or transports substances. (wikipedia.org)
  • Mitochondria
  • They will therefore have a large surface area provided by the microvilli and due to the need for active transport across their cell membranes they will contain a large number of mitochondria providing them with ATP. (biologyguide.net)
  • Importantly, the endomembrane system does not include the membranes of chloroplasts or mitochondria, but might have evolved from the latter (see below: Evolution). (wikipedia.org)
  • cells
  • There was just one problem: Reflecting Ebola's ingenuity, both targets reside only in lysosomes deep within cells-making them invisible to the immune system and shielded from attack by conventional antibodies. (yu.edu)
  • Lysosomes are cell organelles found in most animal cells. (wikipedia.org)
  • Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). (uniprot.org)
  • The first proposal that the membranes within cells form a single system that exchanges material between its components was by Morré and Mollenhauer in 1974. (wikipedia.org)
  • Some cells can form gap junctions that connect their cytoplasm to the cytoplasm of adjacent cells. (wikipedia.org)
  • molecules
  • Knowing precisely where the antibodies attach to the glycoprotein molecules and when and how they act to neutralize ebolaviruses, we can begin to craft broadly effective immunotherapies," says Dr. Dye. (eurekalert.org)
  • Knowing precisely where the antibodies attach to the glycoprotein molecules and when and how they act to neutralise Ebola viruses, we can begin to craft broadly effective immunotherapies,' said John M Dye, from the US Army Medical Research Institute of Infectious Diseases. (tribuneindia.com)
  • tumor
  • This suggests that the three glycoproteins are involved in tumor development, specifically in the processes of angiogenesis and tissue remodeling. (wikipedia.org)
  • cholesterol
  • NPC1, which normally helps transport cholesterol within the cell, offers Ebola virus its only means of escaping the lysosome and multiplying. (yu.edu)