• gene
  • These results suggest that complex interactions of viral auxiliary and nonauxiliary gene functions with the host cell determine the ability to establish chronic virus producers. (umassmed.edu)
  • virus
  • Tests of a series of recombinants between NL4-3 and HXB-2 revealed that 5' internal sequences as well as fragments containing defective auxiliary genes affected the establishment of chronic virus producers. (umassmed.edu)
  • Viral envelope sequences and levels of virus production did not correlate with the ability to establish chronic virus producers. (umassmed.edu)
  • If a virus causes these morphological changes in the host cell, it is said to be cytopathogenic. (wikipedia.org)
  • Bovine viral diarrhea (BVD) or bovine viral diarrhoea (UK English), and previously referred to as bovine virus diarrhoea (BVD), is a significant economic disease of cattle that is endemic in the majority of countries throughout the world. (wikipedia.org)
  • The causative agent, bovine viral diarrhea virus (BVDV), is a member of the Pestivirus genus of the family Flaviviridae. (wikipedia.org)
  • Persistently infected animals are the most important source of the virus, continuously excreting a viral load one thousand times that shed by acutely infected animals. (wikipedia.org)
  • At the time of its discovery little was known about the effects of the virus or whether it played any role whatsoever in the development of lymphosarcoma in the cattle. (wikipedia.org)
  • RIGVIR is non-pathogenic, non-genetically modified wild type virus from Picornaviridae family (Enterovirus genus) - Enteric Cytopathogenic Human Orphan, type 7 (ECHO-7). (wikipedia.org)
  • diarrhea
  • The most commonly reported side effects are subfebrile temperature, pain in the tumor, fatigue, drowsiness, and dyspepsia (diarrhea). (wikipedia.org)
  • cells
  • Cytopathic effect or cytopathogenic effect (abbreviated CPE) refers to structural changes in host cells that are caused by viral invasion. (wikipedia.org)
  • Effects influencing the status of the cells - for example, changes in cell adhesion, cytotoxicity, cell proliferation, cell-cell interactions, and morphological changes - lead to changes in the impedance measurements and can therefore be easily and quickly detected in real time. (selectscience.net)
  • PCV1 persisted in most cell lines without causing any visible changes, while PCV2-transfected cells show cytopathogenic alterations. (pamfa.org)
  • certain
  • Moreover, in the case of falciparum malaria, which is nonrelapsing, complete eradication could be effected by single injections of this preparation provided certain qualifications were fulfilled. (ajtmh.org)