Our data have important implications for cyclic nucleotide-mediated signal transduction. (nih.gov)
A cyclic nucleotide, unlike other nucleotides, has a cyclic bond arrangement between the ribose sugar and the phosphate group. (pancreapedia.org)
A cyclase enzyme (lyase) catalyzes the formation of the cyclic nucleotide from its nucleotide triphosphate precursor ( Figure 1 ). (pancreapedia.org)
Cyclic nucleotides form when the phosphate group of the molecule of nucleotide triphosphate (ATP or GTP) is attacked by the 3' hydroxyl group of the ribose, forming a cyclic 3',5'-phosphate ester with release of pyrophosphate. (pancreapedia.org)
Cyclic nucleotide signaling can be initiated by two general mechanisms. (pancreapedia.org)
The end products of this catalytic reaction are a cyclic nucleotide (cyclic AMP or cyclic GMP) and a pyrophosphate group. (pancreapedia.org)
Antithrombotic activities of ferulic acid via intracellular cyclic nucleotide signaling. (uchicago.edu)
Monophosphate5
Inosine 5'- monophosphate (IMP), the most abundant 5'-ribonucleotide in meat, is known to impart an umami taste without the undesired side effects commonly associated with glutamate. (bvsalud.org)
The two well-established cyclic nucleotides are adenosine-3',5'-cyclic monophosphate (cyclic AMP) and guanine-3',5'-cyclic monophosphate (cyclic GMP). (pancreapedia.org)
The non-canonical cyclic nucleotides include the purines inosine-3',5'-cyclic monophosphate (cyclic IMP), xanthosine-3',5'-cyclic monophosphate (cyclic XMP) and the pyrimidines cytidine-3',5'-cyclic monophosphate (cyclic cCMP), uridine-3',5'-cyclic monophosphate (cyclic UMP), and thymidine-3',5'-cyclic monophosphate (cTMP) (145). (pancreapedia.org)
The synthetic plan centered around the key derivative 8-Br-N1-cIDPR (cyclic 8-Br-inosine 5'-diphosphate ribose, 2), which was prepared in only three steps from IMP (inosine 5'-monophosphate) via an unusual enzymatic cyclization reaction. (ox.ac.uk)
A phosphate group at the C1-atom of inositol-monophosphate (IMP) and fructose-1,6-bisphosphate (FBP) is hydrolyzed by a phosphatase IMPase and FBPase in a metal-dependent way, respectively. (rcsb.org)
Voltammetry6
Alternative methods like cyclic voltammetry might offer more practical solutions for rapidly detecting IMP. (bvsalud.org)
However, the cyclic voltammetry approach differentiated IMP concentrations at 0.50 mM or above in aqueous solutions and subsequentially meat extracts from the buffered blank solutions. (bvsalud.org)
In conclusion, cyclic voltammetry holds potential as a rapid and effective approach for detecting IMP in beef and other meat products, offering promising applications for future research. (bvsalud.org)
The cyclic voltammetry (CV) responses of ferrocyanide and ferrocene-dimethanol were used to compare brand new, surface-polished and plasma-treated GC electrodes. (bvsalud.org)
In this paper, the synthesis of poly(3,4-ethylenedioxythiophene) (PEDOT) by cyclic voltammetry (CV) electrochemical deposition and its application in the counter electrode of solid-state dye-sensitized solar cells were studied. (sioc-journal.cn)
The device with PEDOT transparent counter electrode film deposited by cyclic voltammetry could also achieve double-side illumination with good catalytic activity to the electrolyte. (sioc-journal.cn)
Ribose4
Cyclic nucleotides, like other nucleotides, are composed of three functional groups: a ribose sugar, a nitrogenous base, and a single phosphate group. (pancreapedia.org)
A concise synthesis of five new analogues of the second messenger cADPR (cyclic adenosine 5'-diphosphate ribose) is presented. (ox.ac.uk)
[1] [2] The N 1 -glycosidic bond to adenine is what distinguishes cADPR from ADP-ribose (ADPR), the non-cyclic analog. (cloudfront.net)
Nucleotides3
There are two main groups of cyclic nucleotides: the canonical or well-established and the non-canonical or unknown-function cyclic nucleotides. (pancreapedia.org)
An overview of the non-canonical cyclic nucleotides is provided in Section V. (pancreapedia.org)
This cyclic conformation allows cyclic nucleotides to bind to proteins to which other nucleotides cannot. (pancreapedia.org)
Nanoformulated calix[8]arenes functionalized with N -heterocyclic carbene (NHC)-palladium complexes were found to be efficient nano-reactors for Suzuki-Miyaura cross-coupling reactions of water soluble iodo- and bromoaryl compounds with cyclic triol arylborates at low temperature in water without any organic co-solvent. (mdpi.com)
Heterocyclic compounds are cyclic compounds in which one or more ring atoms are not carbon (that is, hetero atoms). (medmuv.com)
HOSTs5
Initial Experiments Experiment One Experiment Two Introduction The software for the ARPA Network exists partly in the IMPs and partly in the respective HOSTs. (ietf.org)
We believe that any good solution to the general problem of interfacing Hosts to IMPs must satisfy at least the following criteria: 1) The characteristics of the connection should be such that the undetected error rate can be expected to be extremely low. (vim.org)
Hosts must order arriving messages anyway, so the IMP need not do it. (kit-jussieu.org)
In spite of the fact that the IMP subnet can deliver up to 80 kb/sec between pairs of Hosts^, virtually no application using Host software has achieved this figure. (kit-jussieu.org)
The following analysis shows that the current Host/Host protocol cannot offer more than 40 kb/sec on a single connection owing to message format overhead, and that this figure drops hyperbolically if the communicating Hosts are separated by several IMPs. (kit-jussieu.org)
HOST-IMP6
Somewhat independently, Gerard DeLoche of UCLA has been working on the HOST-IMP interface. (ietf.org)
Host side) end for the usual Host/IMP interface software. (vim.org)
The Imp-to-Imp protocol [4] has undergone continuous re- vision, and the HOST/IMP interface specification [5] has been modified slightly. (kit-jussieu.org)
This paper deals with the motivations for the redesign of the HOST-to-HOST, IMP-to-IMP, and HOST/IMP communication protocols in the ARPANET. (kit-jussieu.org)
c) HOST/IMP protocol could be changed to allow arbitrarily long messages to be sent from HOST to IMP, as long as the destination IMP need not reassemble or re-order the arriving packets before delivery to the HOST. (kit-jussieu.org)
d) Host level retransmission, positive end-to-end acknowledgments, error detection, duplicate detection, and message ordering, can eliminate the need for many of these features in the IMP/IMP protocol, and the Request for next Message (RFNM) facility in the present HOST/IMP protocol. (kit-jussieu.org)
Chemical2
In enzymology, an IMP cyclohydrolase (EC 3.5.4.10) is an enzyme that catalyzes the chemical reaction IMP + H2O ⇌ {\displaystyle \rightleftharpoons } 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide Thus, the two substrates of this enzyme are IMP and H2O, whereas its product is 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. (wikipedia.org)
Although it does not form unstable cyclic endopc protein + phosphate chetalor of calcium in chemical contraception implicated in the diluent, and 1 differentiation art lymphocytes he stpplied containers at less polished spots, e.G. (stonecottagegardens.com)
Functional1
Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway. (uchicago.edu)
MeSH1
Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
19831
1983. "Relational Grammar and Interaction of Cyclic Rules in Bahasa Malaysia. (sealang.net)
Enzyme3
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. (wikipedia.org)
The systematic name of this enzyme class is IMP 1,2-hydrolase (decyclizing). (wikipedia.org)
This enzyme catalyses the cyclisation of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP, a reaction which is important in de novo purine biosynthesis in archaeal species. (wikipedia.org)
Synthesis1
Thus the purine synthesis starts with IMP synthesis (See the mind map). (hotelsunshine.co.in)
BB&N has specified the software of the IMPs and it is the responsibility of the HOST groups to agree on HOST software. (ietf.org)
Packets3
IMP Transmission and Error Checking After receiving a message from a HOST, an IMP partitions the message into one or more packets. (ietf.org)
Packets are not more than 1010 bits long and are the unit of data transmission from IMP to IMP. (ietf.org)
Packets are reassembled into messages at the destination IMP. (ietf.org)
Summary3
Network Working Group Steve Crocker Request for Comments: 1 UCLA 7 April 1969 Title: Host Software Author: Steve Crocker Installation: UCLA Date: 7 April 1969 Network Working Group Request for Comment: 1 CONTENTS INTRODUCTION I. A Summary of the IMP Software Messages Links IMP Transmission and Error Checking Open Questions on the IMP Software II. (ietf.org)
I . A Summary of the IMP Software Messages Information is transmitted from HOST to HOST in bundles called messages. (ietf.org)
This interface frames blocks of outgoing data with special characters and appends a 24 bit cyclic redundancy check (CRC). (vim.org)
Alternative2
The objections to the link structure notwithstanding, the links are easily programmed within the IMPs and are probably a better alternative to more complex arrangements just because of their simplicity. (ietf.org)
En conclusion, l'utilisation d'huile de margousier, substance plutôt inoffensive pour l'environnement, est une alternative au larvicide d'anophèle. (who.int)
Interface1
At the IMP end, a hardware interface identical in type, but not necessarily in speed, to the usual IMP 50 kilobit modem interface will be used. (vim.org)
Potential1
The basic conclusions reached in this report are: a) Multipacket message facilities can be eliminated without loss of potential throughput, and with a concurrent simplification of IMP software. (kit-jussieu.org)
Links2
RFC 1 Host Software 7 April 1969 Links The link field is a special device used by the IMPs to limit certain kinds of congestion. (ietf.org)
The IMPs place the restriction on these links that no HOST can send two successive messages over the same link before the IMP at the destination has sent back a special message called an RFNM (Request for Next Message). (ietf.org)
Software2
No notion of beginning or ending a conversation is contained in the IMP software. (ietf.org)
In conjunction with the CRC creation and checking, the IMP will be provided with a small amount of "retransmission" software as a front (i.e. (vim.org)
Position2
A deep pocket was in fact found on the surface of IMP cyclohydrolase in a position equivalent to that of active sites of NTN-hydrolases, but an N-terminal nucleophile could not be found. (wikipedia.org)
The enhanced stability of 2 allowed for the direct modification of this cyclic dinucleotide at the 8 position, providing the unsubstituted parent N1-cIDPR (4) as well as the 8-phenyl (5), 8-azido (6), and 8-amino (7) N1-cIDPR analogues. (ox.ac.uk)
Hardware1
A 24 bit cyclic checksum is computed by the transmission hardware and is appended to an outgoing packet. (ietf.org)
Destination1
8] b) Ordering by the destination IMP of messages delivered to a destina- tion HOST can lead to a lockup condition similar to the reassembly lockup experienced in an earlier version of the IMP protocol in connection with multipacket message reassembly [7]. (kit-jussieu.org)
Message2
The trace bit signals the IMPs to record status information about the message and send the information back to the NMC (Network Measurement Center, i.e. (ietf.org)
By "always functioning," we mean that the IMPs are always prepared to transmit another message over them. (ietf.org)