• Oxidative
  • Antioxidant Oxidative stress Peroxidases Noctor G, Foyer CH (Jun 1998). (wikipedia.org)
  • The central question of this paper is whether in plant cells oxidative stress, in particular H2O2, is required for heat stress- and heat shock factor (HSF)-dependent expression of genes. (deepdyve.com)
  • Rapid (15 min) formation of heat shock promoter element (HSE) protein-binding complex of high molecular weight in extracts of heat-stressed or H2O2-treated cells and the inability to form this complex after ascorbate treatment suggests that oxidative stress affects gene expression via HSF activation and conversely, that H2O2 is involved in HSF activation during the early phase of heat stress. (deepdyve.com)
  • scavenger
  • Clinically, in a disease ameliorated by ascorbate, there is a suppression of symptoms only with very high doses and approximately to that extent which a nonrate-limited, antioxidant free radical scavenger , might be expected to affect that disease process if all harmful free radicals and highly reactive oxidizing substances were quenched. (eco-supplements.com)
  • genes
  • Significant induction of the genes tested after diamid treatment and moderate expression of the sHSP genes in the presence of 50 mM ascorbate at 37°C occurred without activation of HSF, indicating that other mechanisms may be involved in stress signalling. (deepdyve.com)
  • redox
  • Using high resolution crystal structures, a detailed catalytic cycle has been derived for Prxs, including a model for the redox-regulated oligomeric state proposed to control enzyme activity. (wikipedia.org)
  • vitamin
  • Knowledge of the known vitamin functions of ascorbate would not have allowed one to predict these beneficial results. (eco-supplements.com)
  • It is thought that commonly the rate-limiting step in the last series of reactions is that catalyzed by glutathione peroxidase and its cofactor selenium, but other substances which could limit all this are the vitamin E, vitamin C, vitamin B2, vitamin B3, cysteine, etc. (vitaminc.foundation)
  • high
  • Since even at very high doses, ascorbate is virtually nontoxic, it may be given in the enormous doses necessary to quench almost all unwanted free radicals and oxidants. (eco-supplements.com)
  • Low or moderate doses (doses substantially below bowel tolerance) usually had no noticeable immediate beneficial effects, but high doses (doses just below the amount that would produce diarrhea in a patient tolerant to ascorbate) would have the effect of markedly suppressing symptoms as the high dose levels were reached. (eco-supplements.com)
  • The heat stress induction of a high mobility HSE-binding complex, characteristic for later phase of heat shock response, was blocked by ascorbate and DPI. (deepdyve.com)
  • functional
  • Understanding functional diversity and substrate specificity in haem peroxidases: what can we learn from ascorbate peroxidase? (wikipedia.org)
  • Liu, Jin-Yuan 2006-08-30 00:00:00 A novel cDNA of phospholipid hydroperoxide glutathione peroxidase (PHGPx), which encodes a functional protein capable of complementing the yeast PHGHX-deletion mutant, was recently discovered in radish (Raphanus sativus) and designated as RsPHGPx [Yang X-D, Li W-J, Liu J-Y (2005) Biochim Biophys Acta 1728:199- (deepdyve.com)
  • activity
  • It displayed GSH-dependent peroxidase activity and exhibited the largest affinity to and the highest catalytic efficiency on phosphatidylcholine hydroperoxide, suggesting that phospholipid hydroperoxide is probably the optimum substrate for RsPHGPx. (deepdyve.com)
  • complex
  • H2O2 was unable to induce this complex suggesting that H2O2 is involved only in the early stages of HSF activation. (deepdyve.com)
  • higher
  • The concentration of H2O2 in the pathogen inoculated seedlings was two folds higher at 12 h after pathogen inoculation compared to control. (deepdyve.com)