• Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin. (medscape.com)
  • Virchow initially described calcinosis cutis in 1855. (medscape.com)
  • Calcinosis cutis is classified into 4 major types according to etiology: dystrophic, metastatic, iatrogenic, and idiopathic. (medscape.com)
  • These include calcinosis cutis circumscripta, calcinosis cutis universalis, tumoral calcinosis, and transplant-associated calcinosis cutis. (medscape.com)
  • In all cases of calcinosis cutis, insoluble compounds of calcium are deposited within the skin due to local and/or systemic factors. (medscape.com)
  • The pathogenesis of calcinosis cutis is not completely understood and a variety of factors allow for different clinical scenarios to occur. (medscape.com)
  • Some infectious granulomas produce 1,25-vitamin D. Infections that may result in calcinosis cutis include onchocerciasis, cysticercosis, histoplasmosis, cryptococcosis, and intrauterine herpes simplex. (medscape.com)
  • In the setting of dermatomyositis, calcinosis cutis is associated with longer disease duration, fingertip ulcers, and NXP-2 autoantibodies. (medscape.com)
  • Dystrophic calcinosis cutis is most common. (medscape.com)
  • Calcinosis cutis circumscripta tends to arise in the second half of life. (medscape.com)
  • Calcinosis cutis universalis occurs in the second decade of life. (medscape.com)
  • Calcinosis cutis complicating adult-onset dermatomyositis. (medscape.com)
  • Calcinosis cutis universalis with joint contractures complicating juvenile dermatomyositis. (medscape.com)
  • Marzano AV, Kolesnikova LV, Gasparini G, Alessi E. Dystrophic calcinosis cutis in subacute lupus. (medscape.com)
  • Miteva L, Pramatarov K, Vassileva S. Calcinosis cutis in childhood systemic lupus erythematosus. (medscape.com)
  • Extensive calcinosis cutis with systemic lupus erythematosus. (medscape.com)
  • Tristano AG, Villarroel JL, Rodriguez MA, Millan A. Calcinosis cutis universalis in a patient with systemic lupus erythematosus. (medscape.com)
  • Solitary milialike idiopathic calcinosis cutis: a case unassociated with Down syndrome. (medscape.com)
  • Sais G, Jucglà A, Moreno A, Peyrí J. Milia-like idiopathic calcinosis cutis and multiple connective tissue nevi in a patient with Down syndrome. (medscape.com)
  • INTRODUCTION - The term "calcinosis cutis" describes the deposition of insoluble calcium salts in the skin and subcutaneous tissue. (medilib.ir)
  • The treatment of calcinosis cutis is often challenging, and the subtype influences the approach to treatment. (medilib.ir)
  • The management of the various subtypes of calcinosis cutis will be reviewed here. (medilib.ir)
  • The diagnosis and evaluation of patients with calcinosis cutis is discussed separately. (medilib.ir)
  • See "Calcinosis cutis: Etiology and patient evaluation" . (medilib.ir)
  • DYSTROPHIC CALCINOSIS CUTIS - Dystrophic calcinosis cutis, the most common form of calcinosis cutis, results from local tissue injury. (medilib.ir)
  • Treatment principles - The treatment of dystrophic calcinosis cutis associated with autoimmune connective tissue disease is often difficult. (medilib.ir)
  • Do the signs and symptoms of calcinosis cutis warrant treatment? (medilib.ir)
  • Treatment of calcinosis - Treatment of calcinosis cutis associated with autoimmune connective tissue diseases involves careful consideration of the need for treatment and the selection of an appropriate treatment regimen. (medilib.ir)
  • Decision to treat - Consideration of the severity of the signs and symptoms of calcinosis cutis is important because the response to treatment is variable and unpredictable, and there is risk for treatment-related adverse effects. (medilib.ir)
  • Clinical follow-up without intervention to reduce calcium deposits is a reasonable option for calcinosis cutis that is asymptomatic, nonprogressive, unassociated with internal involvement, and of minimal concern to the patient. (medilib.ir)
  • Surgery - Surgical removal of calcinosis may be useful for patients with discrete, symptomatic areas of calcinosis cutis as the primary treatment or as an adjunct to medical therapy. (medilib.ir)
  • Although early reports documenting poor wound healing and sinus track formation led to the historical avoidance of surgical procedures for dystrophic calcinosis cutis, subsequent reports suggest that surgery can be effective for some patients. (medilib.ir)
  • Duration of therapy - Patients who respond to systemic pharmacologic therapies for calcinosis cutis are often maintained on continuous or intermittent treatment for months to years in an attempt to reduce risk for recurrence of disease. (medilib.ir)
  • Methotrexate-Exposed fathers showed aplasia cutis congenita and mental health care. (ultimate-vsb.cz)
  • Although initial reports were following intramuscular injections, the reaction has since also been reported following subcutaneous, intravenous, and intraarticular injections. (wikipedia.org)
  • Livedoid dermatitis is a iatrogenic cutaneous reaction that occurs immediately after a drug injection. (wikipedia.org)
  • Iatrogenic lipoatrophy is typically caused by medication injections. (biomedcentral.com)
  • FETROJA® is indicated in patients 18 years of age or older who have limited or no alternative treatment options for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis caused by the following susceptible Gram-negative microorganisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and Enterobacter cloacae complex. (globalrph.com)
  • Effective use of lymphoscintigraphy to plan therapy requires an understanding of the pathophysiology of lymphedema and the influence of technical factors such as selection of the radiopharmaceutical, imaging times after injection, and patient activity after injection on the images. (snmjournals.org)
  • And for the past 5 days, I've been jamming pills down her throat and administering injections and subcutaneous IV fluids. (blogspot.com)
  • Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)
  • Erythema nodosum is an inflammation of the fat cells in the subcutaneous tissue. (racgp.org.au)
  • Evaluation of tissue response to dental alloys by subcutaneous implantation. (cdc.gov)
  • A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. (maineusgbc.org)
  • Lipoatrophy is defined as disappearance of the subcutaneous fat, without exudative reactions or appreciable fibrosis and just as lipodystophy, it is divided into generalized, partial and localized forms [ 1 ]. (biomedcentral.com)
  • these are called depot injections. (maineusgbc.org)
  • We suggest that a single serum pattern for LH obtained 30 to 60 minutes after depot leuprolide injection in kids supplies a handy and accurate assessment of remedy efficacy. (unisel.edu.my)
  • It presents as an immediate, extreme pain around the injection site, with overlying skin rapidly becoming erythematous, violaceous, or blanched ("ischemic pallor"): 124 and sometimes with reticular pattern. (wikipedia.org)
  • When it comes to describing the journey that a drug takes through the body, pharmacologists like to employ a cute little acronym: ADME. (drugsandpoisons.com)
  • To recap: Pharmacologists use a cute little acronym, ADME, to describe the path that a drug takes through the body: Absorption into the bloodstream, Distribution to the tissues, Metabolism in some of those tissues to produce metabolites, and finally Elimination in body wastes like urine and poop. (drugsandpoisons.com)
  • Long term therapy with subcutaneous testosterone, or testosterone combined with anastrozole, did not increase the incidence of ibc. (jovenslivres.com)
  • The reaction is associated with a range of both injection sites and drugs. (wikipedia.org)
  • Semoga membantu, selamat mencoba dan semoga berhasil, hgh injection joint pain. (phonostorage.com)
  • Livedoid dermatitis has been reported to occur with many different drug injections, including: penicillins, local anesthetics (e.g. lidocaine), vaccines (e.g. (wikipedia.org)
  • Necrotizing fasciitis at a possible site of insulin injection in the left upper part of the thigh in a 50-year-old obese woman with diabetes. (medscape.com)
  • And instead of a cute cap, he had half a fro. (blogspot.com)
  • Potentiates stress-induced increase regarded Mona as a strange character, even though she was very cute something more actionable to work with. (nextslide.com)
  • Although initial reports were following intramuscular injections, the reaction has since also been reported following subcutaneous, intravenous, and intraarticular injections. (wikipedia.org)
  • The recommended starting dose for the first treatment cycle, for all patients regardless of baseline hematology values, is azacitidine for injection 75 mg/m 2 daily for 7 days to be administered by subcutaneous injection or intravenous infusion. (nih.gov)
  • The recommended starting dose for the first treatment cycle,for all patients regardless of base line hematology values,is azacitidine for injection75 mg/m 2 daily for 7 days to be administered by subcutaneous injection or intravenous infusion.Premedicate for nausea and vomiting. (nih.gov)
  • 2%) Resulting in Clinical Intervention (Subcutaneous or Intravenous Route): Discontinuation: leukopenia, thrombocytopenia, neutropenia. (drugcentral.org)
  • This policy has been updated to communicate the Company's coverage position for Abatacept (Orencia) injection for intravenous use, in accordance with US Food and Drug Administration ​ (FDA) to include a four-dose limit for the Prophylaxis of Acute Graft-Versus-Host Disease (aGVHD). (ibx.com)
  • Abatacept (Orencia) injection for intravenous use is considered medically necessary and, therefore, covered when used in individuals who have moderately to severely active polyarticular juvenile idiopathic arthritis ​(pJIA). (ibx.com)
  • If the individual has not previously received a bDMARD to treat pJIA, abatacept (Orencia) injection for intravenous use is only eligible for coverage when the individual has a documented failure, contraindication, or intolerance to golimumab (Simponi Aria), or there is a clinical reason that a trial of golimumab (Simponi Aria) would be otherwise inappropriate for the member. (ibx.com)
  • However, medications including subcutaneous fluids and injections such as insulin require additional expertise, and an add-on fee. (localpawpals.com)
  • And for the past 5 days, I've been jamming pills down her throat and administering injections and subcutaneous IV fluids. (blogspot.com)
  • Revitalisation of the skin and subcutaneous tissues is carried out by means of cross-linked hyaluronic acid. (crpub.org)
  • Necrotizing fasciitis is a rapidly progressive inflammatory infection of the fascia, with secondary necrosis of the subcutaneous tissues. (medscape.com)
  • Börjeson's syndrome , Börjeson-Forssman-Lehmann syndrome a hereditary syndrome, transmitted as an X-linked recessive trait, characterized by severe mental retardation, epilepsy, hypogonadism, hypometabolism, marked obesity, swelling of the subcutaneous tissues of the face, and large ears. (topgrowupclinic.eu)
  • Each bottle is to be used as an Imaging Bulk Package for dispensing multiple single doses of iopamidol injection for multiple patients, using an automated contrast injection system, contrast management system, or contrast media transfer set approved or cleared for use with this contrast agent in this Imaging Bulk Package. (nih.gov)
  • The number of treatment sessions, treatment volumes, doses, injections required for each anatomic area, and associated adverse events were recorded. (nih.gov)
  • Most patients received average daily doses between 50 and 100 mg/m2.In Study 4, total of 175 patients with higher-risk MDS (primarily RAEB and RAEB-T subtypes) were exposed to azacitidine for injection. (drugcentral.org)
  • Most patients received daily azacitidine for injection doses of 75 mg/m2. (drugcentral.org)
  • Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: twenty-four-week efficacy and safety results of a randomized, placebo-controlled study. (medicalletter.org)
  • Azacitidine for injection is a nucleoside metabolic inhibitor indicated for the treatment of patients with the following FAB myelodysplastic syndrome (MDS) subtypes: Refractory anemia (RA) or refractory anemia with ringed sideroblasts (RARS) (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-T), and chronic myelomonocytic leukemia (CMMoL). (nih.gov)
  • These highlights do not include all the information needed to use AZACITIDINE FOR INJECTION safely and effectively. (nih.gov)
  • See full prescribing information for AZACITIDINE FOR INJECTION. (nih.gov)
  • Tumor Lysis Syndrome: Azacitidine for injection may cause fatal or serious tumor lysis syndrome, including in patients with MDS. (nih.gov)
  • Embryo-Fetal Risk: Azacitidine for injection can cause fetal harm. (nih.gov)
  • Azacitidine for injection is pyrimidine nucleoside analog of cytidine. (drugcentral.org)
  • Azacitidine for injection is believed to exert its antineoplastic effects by causing hypomethylation of DNA and direct cytotoxicity on abnormal hematopoietic cells in the bone marrow. (drugcentral.org)
  • 6.1 Adverse Reactions in Clinical Trials Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.The data described below reflect exposure to azacitidine for injection in 443 MDS patients from clinical studies. (drugcentral.org)
  • In Studies 1, and 3, total of 268 patients were exposed to azacitidine for injection, including 116 exposed for cycles (approximately months) or more and 60 exposed for greater than 12 cycles (approximately one year). (drugcentral.org)
  • Azacitidine for injection was studied primarily in supportive-care controlled and uncontrolled trials (n=150 and n=118, respectively). (drugcentral.org)
  • Table presents adverse reactions occurring in at least 5% of patients treated with azacitidine for injection (subcutaneous) in Studies and 2. (drugcentral.org)
  • Includes adverse reactions from all patients exposed to azacitidine for injection, including patients after crossing over from observations. (drugcentral.org)
  • It is not advisable to increase the amount of Macrolane VRF 30, as this would make superficial injection with thin needles more difficult. (crpub.org)
  • Necrotizing fasciitis at a possible site of insulin injection in the left upper part of the thigh in a 50-year-old obese woman with diabetes. (medscape.com)
  • Intravascular injection of a radiopaque diagnostic agent opacifies those vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs. (nih.gov)
  • Following intravascular injection, radiopaque diagnostic agents are immediately diluted in the circulating plasma. (nih.gov)
  • Bilateral Subcutaneous Lipomas: The Potential of Point-Of-Care Ultrasonography as a Diagnostic Tool in Dermatology. (mayo.edu)
  • Livedoid dermatitis is a iatrogenic cutaneous reaction that occurs immediately after a drug injection. (wikipedia.org)
  • The reaction is associated with a range of both injection sites and drugs. (wikipedia.org)
  • Delayed Adverse Subcutaneous Reaction to a New Family of Hyaluronic Acid Dermal Fillers With Clinical, Ultrasound, and Histologic Correlation. (nvcg.nl)
  • Livedoid dermatitis has been reported to occur with many different drug injections, including: penicillins, local anesthetics (e.g. lidocaine), vaccines (e.g. (wikipedia.org)
  • The authors sought to describe the experience with ATX-101 subcutaneous injections for body and jawline contouring and evaluate its safety. (nih.gov)
  • Cellulitis is an infection of the deeper subcutaneous layers of the skin with a classic set of signs and symptoms including redness, pain, and warmth, and swelling. (contourderm.com)
  • Each mL of ISOVUE-300 (Iopamidol Injection 61%) provides 612 mg iopamidol with 1 mg tromethamine and 0.39 mg edetate calcium disodium. (nih.gov)
  • The speed of spread is directly proportional to the thickness of the subcutaneous layer. (medscape.com)
  • Sometimes a small blood vessel in the subcutaneous layer gets nicked when closing with a suture. (blackandtansiamese.com)
  • This single-arm, single-center observational study included 201 patients who underwent injection adipocytolysis with ATX-101 (area-adjusted dose of 2 mg/cm2) in the jowl, abdomen (upper/lower), thigh (inner/outer/banana roll), arm, anterior periaxillary fat, back (lower/upper/nape/lipoma), knee (anterior/medial), chest, and/or neck. (nih.gov)
  • Ninety-one percent (125/137) of patients saw an improvement in midface fullness 12 weeks after injection. (stylebeautyonline.com)
  • Most patients also experience small bumps at the injection sites, which last about five to seven days, but can be concealed with makeup. (contourderm.com)
  • ISOVUE® Imaging Bulk Package For use only with an automated contrast injection system, contrast management system, or contrast media transfer set approved or cleared for use with this contrast agent in this Imaging Bulk Package. (nih.gov)
  • Filler migration to the forehead due to multiple filler injections in a patient addicted to cosmetic fillers. (nvcg.nl)
  • I've owned 4 elderly cats in the past and have experience with daily medications that needed to be administered either in pill or injection form. (meowtel.com)
  • The population in the subcutaneous studies (n=220) was 23 to 92 years old (mean 66.4 years), 68% male, and 94% white, and had MDS or AML. (drugcentral.org)
  • Ultrasound and Histologic Examination after Subcutaneous Injection of Two Volumizing Hyaluronic Acid Fillers: A Preliminary Study. (nvcg.nl)
  • ISOVUE (Iopamidol Injection) is a stable, aqueous, sterile, and nonpyrogenic solution for intravascular administration. (nih.gov)
  • Methotrexate-Exposed fathers showed aplasia cutis congenita and mental health care. (ultimate-vsb.cz)