• Lipomatosis is believed to be an autosomal dominant condition in which multiple lipomas are present on the body. (wikipedia.org)
  • Other entities which are accompanied by multiple lipomas include Proteus syndrome, Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis (Madelung disease), Dercum's Disease, familial lipodystrophy, hibernomas, epidural steroid injections with epidural lipomatosis, and familial angiolipomatosis. (wikipedia.org)
  • Approximately 60% of solitary cutaneous lipomas display clonal alterations. (medscape.com)
  • Cutaneous lipomas can cause mild tenderness, and angiolipomas are often tender. (medscape.com)
  • Apparent alopecia and small cutaneous soft lipomas on the face and eyelid. (medscape.com)
  • rarely appear several lipomas producing a condition called lipomatosis. (fastlyheal.com)
  • only valid in the presence of multiple lipomas, that is, lipomatosis. (fastlyheal.com)
  • Multiple lipomas may run in families and be part of a genetic condition (for example, familiar multiple lipomatosis). (msdmanuals.com)
  • Encephalocraniocutaneous lipomatosis (ECCL) is a rare, congenital, neurocutaneous disorder with unilateral lipomatous cutaneous neoplasms devoid of hair and ipsilateral ophthalmologic and neurologic malformations. (medscape.com)
  • There are no effective treatment modalities for encephalocraniocutaneous lipomatosis (ECCL). (medscape.com)
  • Owing to reported midline low-grade gliomas in the suprasellar region in 4 encephalocraniocutaneous lipomatosis (ECCL) patients, some authors also recommend ophthalmologic and endocrinologic control in order to quickly discover any warning signs. (medscape.com)
  • Encephalocraniocutaneous lipomatosis (ECCL) is a rare condition that primarily affects the brain, eyes, and skin of the head and face. (medlineplus.gov)
  • Grade II pilocytic astrocytoma in a 3-month-old patient with encephalocraniocutaneous lipomatosis (ECCL): case report and literature review of low grade gliomas in ECCL. (medscape.com)
  • [ 1 ] They suggested that the man had a previously unreported neurocutaneous syndrome, which they termed encephalocraniocutaneous lipomatosis. (medscape.com)
  • Encephalocraniocutaneous lipomatosis has also become known under the term Fishman syndrome. (medscape.com)
  • All reported cases of encephalocraniocutaneous lipomatosis are sporadic. (medscape.com)
  • A nonhereditary, autosomal mutation that may survive only in a mosaic state may be a cause of the clinical picture of encephalocraniocutaneous lipomatosis. (medscape.com)
  • In 2004, Cultrera et al described a female infant that showed significant overlap of encephalocraniocutaneous lipomatosis with oculocerebrocutaneous Delleman syndrome. (medscape.com)
  • Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis. (medlineplus.gov)
  • Haberland C, Perou M. Encephalocraniocutaneous lipomatosis. (medscape.com)
  • Happle R, Steijlen PM. [Encephalocraniocutaneous lipomatosis. (medscape.com)
  • Observations on encephalocraniocutaneous lipomatosis. (medscape.com)
  • Encephalocraniocutaneous lipomatosis with a mutation in the NF1 gene. (medscape.com)
  • Ayer RE, Zouros A. Encephalocraniocutaneous lipomatosis: a review of its clinical pathology and neurosurgical indications. (medscape.com)
  • Hauber K, Warmuth-Metz M, Rose C, Brocker EB, Hamm H. Encephalocraniocutaneous lipomatosis: a case with unilateral odontomas and review of the literature. (medscape.com)
  • Moog U. Encephalocraniocutaneous lipomatosis. (medscape.com)
  • Encephalocraniocutaneous lipomatosis: a rare neurocutaneous syndrome. (medscape.com)
  • Encephalocraniocutaneous lipomatosis with didymosis aplasticopsilolipara. (medscape.com)
  • Almer Z, Vishnevskia-Dai V, Zadok D. Encephalocraniocutaneous lipomatosis: case report and review of the literature. (medscape.com)
  • Valladares MJ, Blanco MJ, Lopez-Lopez F, Gonzalez F. Bilateral ocular involvement in encephalocraniocutaneous lipomatosis. (medscape.com)
  • Thakur S, Thakur V, Sood RG, Thakur CS, Khanna S. Encephalocraniocutaneous lipomatosis with calvarial exostosis - Case report and review of literature. (medscape.com)
  • Pregowska K, Jurkiewicz E, Miszczak-Knecht M, Turska-Kmiec A, Bieganowska K. Persistent multifocal atrial tachycardia in infant with encephalocraniocutaneous lipomatosis: a case report. (medscape.com)
  • Oculocerebrocutaneous and encephalocraniocutaneous lipomatosis syndromes: blind men and an elephant or separate syndromes? (medscape.com)
  • Brain anomalies in encephalocraniocutaneous lipomatosis. (medscape.com)
  • Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis? (medscape.com)
  • Zielinska-Kazmierska B, Grodecka J, Jablonska-Polakowska L, Arkuszewski P. Mandibular osteoma in the encephalocraniocutaneous lipomatosis. (medscape.com)
  • Koishi GN, Yoshida M, Alonso N, Matushita H, Goldenberg D. Encephalocraniocutaneous lipomatosis (Haberland's syndrome): a case report of a neurocutaneous syndrome and a review of the literature. (medscape.com)
  • The patient was tentatively diagnosed with spinal epidural lipomatosis (SEL) secondary to hypothyroidism. (e-jvc.org)
  • Benign symmetric lipomatosis (Madelung's disease). (medscape.com)
  • Ardeleanu V, Chicos S, Georgescu C, Tutunaru D. Multiple benign symmetric lipomatosis -- a differential diagnosis of obesity. (medscape.com)
  • Cutaneous skin tags also known as acrochorda or fibroepithelial polyps are small benign tumours that may either form secondarily over time primarily in areas where the skin forms creases, such as the neck, armpit or groin or may also be present at birth, in which case they usually occur in the periauricular region. (nih.gov)
  • Historically, the clinical diagnoses in patients with PIK3CA activating mutations have included Hemihyperplasia Multiple Lipomatosis (HHML), Vascular Malformations, Scoliosis/Skeletal and Spinal (CLOVES) syndrome, macrodactyly and the related megalencephaly syndromes, Megalencephaly-Capillary Malformation Polymicrogyria (MCAP or M-CM) and Dysplastic Megalencephaly (DMEG) [ 10 ]. (longdom.org)
  • Therapy of cutaneous and subcutaneous lesions, especially on the face and cranium, is challenging. (medscape.com)
  • Proteus syndrome is a rare sporadic disorder that appears with localized macrosomia, congenital lipomatosis, and slow flow vascular malformations, connective tissue nevus, and epidermal nevus. (ac.ir)
  • MCAP is characterized by primary megalencephaly, prenatal overgrowth, brain and body asymmetry, digital anomalies consisting of syndactyly with or without postaxial polydactyly, cutaneous vascular malformations, connective tissue dysplasia involving the skin, joints and subcutaneous tissue, and cortical brain malformations, most commonly polymicrogyria [ 11 , 12 ]. (longdom.org)
  • Named after Sir Alfred Poland, Poland anomaly (PA) is described as an underdevelopment or absence of the chest muscle (pectoralis) on one side of the body and webbing of the fingers (cutaneous syndactyly) of the hand on the same side (ipsilateral hand). (the-medical-dictionary.com)
  • They may be either solitary entities or engaged in multiple lipomatosis, which may have a familial origin or be an acquired disorder. (baskent.edu.tr)
  • Kawaguchi M, Kato H, Tomita H, Hara A, Matsuo M. CT and MR imaging findings of solitary nevus lipomatosus cutaneous superficialis: radiological-pathological correlation. (medscape.com)
  • Klippel-Trenaunay syndrome and Sturge-Weber syndrome are rare disorders with neurologic and cutaneous signs of vascular origin. (pediatricneurosciences.com)
  • Güven M, Anık A, Ünüvar T, İlgün Gürel D, Şendur N. Cutaneous manifestations of obesity in Turkish children: A comparative study. (medscape.com)
  • Viljoen DL, Saxe N, Temple-Camp C. Cutaneous manifestations of the Proteus syndrome. (ac.ir)
  • Gomes da Silva R, Detoffol Bragança R, Ribeiro Costa C, Torres de Melo L, Weiss Telles R, Costa Silva L. Multiple symmetric lipomatosis. (medscape.com)
  • However, lipoma development is known to occur in fewer than 1 in 100 individuals, and only a few examples of multiple cutaneous lipomatosis triggered by this therapy have been documented. (baskent.edu.tr)
  • Here we present a very rare case of lipomatosis in a pediatric patient with GCT under cisplatin therapy, which might be the third report of this kind affecting children. (baskent.edu.tr)
  • Lipomatosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • As a result, exposure to platinum-based drugs throughout infancy can have predictable long-term effects such as infertility, as well as other rare encounters such as lipoma formation and lipomatosis. (baskent.edu.tr)
  • Phakomatosis pigmentovascularis is a distinctive association of cutaneous hemangiomas and melanocytic nevi. (pediatricneurosciences.com)
  • Cytoprotective Polyphenols Against Chronological Skin Aging and Cutaneous Photodamage. (harvard.edu)
  • Primary cutaneous B-cell lymphoblastic lymphoma in children. (medscape.com)
  • BACKGROUND Encephalocraniocutaneous lipomatosis (ECCL) was first announced as a new type of ectomesodermal dysgenesis in 1970 by Haberland and Perou. (nih.gov)
  • Encephalocraniocutaneous lipomatosis (ECCL) is a rare, congenital, neurocutaneous disorder with unilateral lipomatous cutaneous neoplasms devoid of hair and ipsilateral ophthalmologic and neurologic malformations. (medscape.com)
  • [ 1 ] They suggested that the man had a previously unreported neurocutaneous syndrome, which they termed encephalocraniocutaneous lipomatosis. (medscape.com)
  • Encephalocraniocutaneous lipomatosis has also become known under the term Fishman syndrome. (medscape.com)
  • All reported cases of encephalocraniocutaneous lipomatosis are sporadic. (medscape.com)
  • A nonhereditary, autosomal mutation that may survive only in a mosaic state may be a cause of the clinical picture of encephalocraniocutaneous lipomatosis. (medscape.com)
  • There are no effective treatment modalities for encephalocraniocutaneous lipomatosis (ECCL). (medscape.com)
  • Owing to reported midline low-grade gliomas in the suprasellar region in 4 encephalocraniocutaneous lipomatosis (ECCL) patients, some authors also recommend ophthalmologic and endocrinologic control in order to quickly discover any warning signs. (medscape.com)
  • In 2004, Cultrera et al described a female infant that showed significant overlap of encephalocraniocutaneous lipomatosis with oculocerebrocutaneous Delleman syndrome. (medscape.com)
  • When Do Symptoms of Encephalocraniocutaneous lipomatosis Begin? (nih.gov)
  • Encephalocraniocutaneous lipomatosis (ECCL) is a rare congenital syndrome with an unknown etiology. (wustl.edu)
  • Connective tissue naevi are sometimes found in other diseases including tuberous sclerosis, chronic myelocytic leukaemia , syphilis and encephalocraniocutaneous lipomatosis. (dermnetnz.org)
  • The neck and shoulders usually are spared (unlike benign symmetric lipomatosis). (medscape.com)
  • Benign symmetric lipomatosis (Madelung's disease). (medscape.com)
  • Gomes da Silva R, Detoffol Bragança R, Ribeiro Costa C, Torres de Melo L, Weiss Telles R, Costa Silva L. Multiple symmetric lipomatosis. (medscape.com)
  • Ardeleanu V, Chicos S, Georgescu C, Tutunaru D. Multiple benign symmetric lipomatosis -- a differential diagnosis of obesity. (medscape.com)
  • Other entities which are accompanied by multiple lipomas include Proteus syndrome, Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis (Madelung disease), Dercum's Disease, familial lipodystrophy, hibernomas, epidural steroid injections with epidural lipomatosis, and familial angiolipomatosis. (wikipedia.org)
  • Benign symmetric lipomatosis (Madelung disease) - involves diffuse, infiltrative, symmetric painless lipomatous growths affecting the head, neck and shoulder region. (rxharun.com)
  • As in other types of tumors, the exact cause of a lipoma is not known and, although it is sometimes related to a genetic origin , it has only been shown that genetic inheritance is correctly involved with the development of hereditary multiple lipomatosis syndrome, in which the tumors can be both superficial and deep. (fastlyheal.com)
  • A different variant affecting the same residue G12S is associated with Cardio-facio-cutaneous syndrome in HGMD (Nava_2007). (varsome.com)
  • Maculopapular cutaneous mastocytosis (urticaria pigmentosa of the old nomenclature) is by far the most comm. (altmeyers.org)
  • Primary cutaneous B-cell lymphoblastic lymphoma in children. (medscape.com)
  • Cutaneous neurofibroma - Cutaneous neurofibroma is a benign nerve sheath tumor composed of cells of neuromesenchymal origin, including Schwann cells, fibroblasts, perineurial cells, and mast cells. (medilib.ir)
  • Mostly a single tumor is formed, but in 7% of cases it is possible that multiple of them arise, which is known as lipomatosis. (fastlyheal.com)