Cutaneous lichens. Medical search. Frequent questions

Primary Cutaneous Lichen Amyloidosis is a rare condition in which there is a deposition of amyloid in the dermis layer of the skin without systemic involvement. (247healthblog.com)
In primary localized cutaneous amyloidosis, the deposition of amyloid occurs in previously apparent normal skin with no evidence of deposits occurring in the internal organs. (247healthblog.com)
Lichen Amyloidosis (LA) is a different manifestation of the same disease process which is characterized by the closely set, discrete, brown-red papules that are commonly seen on the legs especially on the shins and often shows scaling. (247healthblog.com)
The lesions of lichen amyloidosis itch severely. (247healthblog.com)
What are the Symptoms of Primary Cutaneous Lichen Amyloidosis? (247healthblog.com)
Lichen Amyloidosis (LA) is associated with severe itching (pruritis). (247healthblog.com)
Adnexal structures and blood vessels are not invaded in lichen amyloidosis but are invaded in other types of amyloidosis. (247healthblog.com)
Skin biopsy and histological investigations are usually suggested when suspected with lichen amyloidosis. (247healthblog.com)
Modern treatment of lichen amyloidosis generally involves the prescription of corticosteroid creams, anti-histamines, dermabrasion (removal of superficial layers of the skin) and in severe cases there is an excision of the individual lesion but recurrence is common. (247healthblog.com)
What is the Cause of Primary Cutaneous Lichen Amyloidosis According to Ayurveda? (247healthblog.com)
According to Ayurveda, the cause of primary cutaneous lichen amyloidosis is the accumulation of endotoxins or Ama in the body. (247healthblog.com)
This churna also removes Ama formation or endotoxins within the system therefore quite effective for the treatment of primary cutaneous lichen amyloidosis. (247healthblog.com)
Lichen amyloidosis, a variant of localized cutaneous amyloidosis, is characterized by discrete, intensely pruritic, hyperkeratotic brown-coloured papules and plaques (1). (medicaljournals.se)
All are characterized by variable and limited response frequently followed by reoccurrence of lichen amyloidosis. (medicaljournals.se)
A 67-year-old Caucasian woman with a history of lichen amyloidosis on the upper back for more than 26 years presented to the itch clinic of the Department of Dermatology in 2007 because of severe therapy-resistant pruritus within the affected skin area. (medicaljournals.se)
The lichen amyloidosis had begun in 1982, the size of a hens egg, constantly extending in a triangular area of the upper and lower back up to a size of 30 × 25 cm in 2007. (medicaljournals.se)
She denied any sun or ultraviolet (UV) exposure before lichen amyloidosis had begun. (medicaljournals.se)
Her past medical history comprised arterial hypertension, which had started 20 years after onset of lichen amyloidosis. (medicaljournals.se)
The appearance of the lichen amyloidosis improved continuously with a decrease in papules, infiltration and pigmentation. (medicaljournals.se)
The patient's lichen amyloidosis has improved significantly (Fig. 2) and she remains almost free of pruritus (VAS 1-3). (medicaljournals.se)
MEN 2A is associated with medullary thyroid carcinoma (MTC), phaeochromocytoma, primary hyperparathyroidism, cutaneous lichen amyloidosis and Hirschprung's disease and MEN 2B with MTC, phaeochromocytoma, ganglioneuromatosis of the aerodigestive tract, musculoskeletal and ophthalmologic abnormalities. (nih.gov)
with resultant hyperparathyroidism), and occasionally cutaneous lichen amyloidosis. (msdmanuals.com)
Primary localized cutaneous amyloidosis (PLCA) is a condition in which clumps of abnormal proteins called amyloids build up in the skin, specifically in the wave-like projections (dermal papillae) between the top two layers of skin (the dermis and the epidermis). (medlineplus.gov)
The appearance of these patches defines three forms of the condition: lichen amyloidosis, macular amyloidosis, and nodular amyloidosis. (medlineplus.gov)
Lichen amyloidosis is characterized by severely itchy patches of thickened skin with multiple small bumps. (medlineplus.gov)
In some affected individuals, the patches have characteristics of both lichen and macular amyloidosis. (medlineplus.gov)
Mutations in either gene are likely involved in lichen and macular amyloidosis, which are thought to be related conditions that arise through similar disease mechanisms. (medlineplus.gov)
In lichen and macular amyloidosis, it is thought that scratching the itchy skin causes skin cells to undergo apoptosis, releasing proteins that abnormally clump together and form amyloids. (medlineplus.gov)
Primary cutaneous amyloidosis (keratinamyloidosis) with dense papules and very intense lesional pruritus. (altmeyers.org)
a recent skin biopsy showed more established features of lichen amyloidosis. (bvsalud.org)
It is debatable whether the cutaneous amyloidosis was a secondary or primary phenomenon. (bvsalud.org)
Our report highlights that the diagnosis of epidermolysis bullosa pruriginosa may be obscured when cutaneous amyloidosis is coexistent. (bvsalud.org)

Lesions of this syndrome share features of both lupus erythematosus and lichen planus. (wikipedia.org)
Annular lesions on the head and neck could also be secondary to petaloid seborrheic dermatitis, tinea corporis, discoid lupus erythematosus, subacute lupus erythematosus, cutaneous sarcoidosis, or granuloma annulare. (ccjm.org)
and for locating a splinter, examining nail fold capillaries in cutaneous lupus erythematosus or systemic sclerosis, and detection of melanoma. (medgadget.com)
It is not uncommon to find that a single disease (say cutaneous lupus, inflammatory vitiligo, or lichen sclerosus) may sometimes present with both hypo as well as hyperpigmented lesions (occasionally, a single patch displaying both variants), indistinguishable histologically. (lww.com)
Emergency Central , emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114176/all/Discoid__chronic_cutaneous__lupus_erythematosus. (unboundmedicine.com)
Cutaneous lupus erythematosus Hair loss, also called alopecia, can occur on any part of the body. (msdmanuals.com)
The condition often shares the features of a variety of autoimmune diseases, such as lichen planus, Sjögren's syndrome, systemic lupus erythematosus or primary biliary cirrhosis [12, 13]. (bvsalud.org)
Local (intra-articular or intralesional) injection of [CV004 trade name] may be given as part of the short-term management of inflammatory joint and tendon disorders, and localised inflammatory and hypertrophic skin lesions including those of lichen simplex, lichen planus, granuloma annulare, discoid lupus erythematosus, and keloids. (who.int)

The scalp is rarely affected by a condition known as lichen planopilaris, acuminatus, follicular lichen planus, and peripilaris, characterised by violaceous, adherent follicular scale with progressive scarring alopecia. (wikipedia.org)
While lichen planus and lichen planopilaris may occur together, aside from sharing the term 'lichen' and revealing inflammation on skin biopsy, there is neither established data on their co-occurrence nor data to suggest a common etiology. (wikipedia.org)
Lichen planopilaris is considered an orphan disease with no definitive prevalence data and no proven effective treatments. (wikipedia.org)
Considered a clinical variant of lichen planopilaris (LPP), it has distinctive features and associations which distinguish it from LPP. (skintherapyletter.com)
1 Clinically, the follicular features appeared identical to lichen planopilaris (LPP) however, the pattern of the disease was distinct from typical LPP in several ways. (skintherapyletter.com)
Less common causes include primary hair shaft abnormalities (that is, the abnormality originates in the hair shaft), lichen planopilaris (lichen planus of the scalp) and frontal fibrosing alopecia, , and rare skin conditions. (msdmanuals.com)

Cutaneous lichen planus (CLP) most commonly involves the flexor surfaces of the extremities and presents as small itchy violaceous Papules in middle-aged adults. (hindawi.com)
Lichen planus which is characterized by the papules with a white lacy appearance on mucosal surfaces. (247healthblog.com)
Although lichen planus can present with a variety of lesions, the most common presentation is as a well defined area of purple-coloured, itchy, flat-topped papules with interspersed lacy white lines (Wickham's striae). (wikipedia.org)
Oral lichen planus (OLP) is a chronic mucocutaneous disorder that presents in a wide range of clinical forms, such as unilateral or bilateral white striations, papules, or plaques on the buccal mucosa, labial mucosa, tongue, and gingiva. (medscape.com)
Typically, the clinical diagnosis of lichen planus is made when it presents as the class variant, characterized by purple, polygonal papules. (jcadonline.com)
Cutaneous Lichen Planus patients with papules and extreme skin dryness respond very well to Sulphur. (homoeoonline.com)
Oral lichen planus (OLP) is a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa, tongue, and gingivae. (medscape.com)

No therapeutic modality has been rigorously evaluated for the treatment of lichen nitidus because of the rarity, lack of significant symptomatology, and disappearance of this disease within one or several years. (medscape.com)
It is also of great help in the treatment of lichen Planus. (homoeoonline.com)
A natural medicine that gives wonderful results in the treatment of Lichen Planus is Thuja. (homoeoonline.com)

In clinical practice, he specializes in medical dermatology and dermatopathology with a specific focus in cutaneous granulomatous disorders (sarcoidosis and granuloma annulare). (yale.edu)

It was originally named "lichen ruber planus" and "lichen psoriasis" [ 5 ]. (hindawi.com)
It is also used to distinguish certain skin conditions, such as lichen planus, from others such as psoriasis and eczema. (medgadget.com)
Has been used as a photosensitizer for photodynamic therapy † [off-label] (PDT) for topical treatment of dermatologic or mucocutaneous infections (e.g., herpes labialis, eczema herpeticum, oral candidiasis, cutaneous leishmaniasis, chromoblastomycosis) or chronic dermatologic or mucocutaneous conditions (e.g., plaque psoriasis, oral lichen planus). (drugs.com)
Cutaneous psoriasis is a chronic inflammatory disease of the epidermis. (centrethermalavene.com)

[ 19 ] Research published in 2015 also suggests that osteopontin, CD44, and survivin may be involved in the pathogenesis of oral lichen planus. (medscape.com)
The pathogenesis of oral lichen planus. (medscape.com)

This is a retrospective case series of cutaneous squamous cell carcinomas (SCCs) which were incompletely excised in National Skin Centre, Singapore from 1991 to 1995. (annals.edu.sg)
Biopsy also helps detect squamous cell carcinoma , the risk of which is increased in lichen planus. (amboss.com)
Because lichen sclerosus is associated with increased risk of squamous cell carcinoma in women with genital involvement, it is important for those affected to have life long screening examinations as well as continued treatment to keep the disorder under control. (rarediseases.org)
Recent data suggest that OLR present a greater percentage of malignant transformation than OLP and, although the association between cancer and OLP has been documented in scientific reports, there is no association between squamous cell carcinoma and cutaneous lichen planus [ 4 - 6 ]. (ecancer.org)
Younes F, Quartey EL, Kiguwa S, Partridge M. Expression of TNF and the 55-kDa TNF receptor in epidermis, oral mucosa, lichen planus and squamous cell carcinoma. (medscape.com)

These systemic disorders and the associated renal diseases and cutaneous manifestations are tabulated in Table 1, below. (medscape.com)
Sclerotic features, systemic involvement, and monoclonal gammopathy are absent in localized lichen myxedematosus. (medscape.com)
OBJECTIVE: We sought to determine whether viral transcripts were present within the skin of patients with HCV and LP, and if systemic virologic response to interferon alfa and ribavirin correlated with response of the LP.Materials and methods A total of 4 men and 1 woman all presented with cutaneous eruptions of LP, and 1 had oral LP lesions. (thedoctorsdoctor.com)
Reported associations between oral lichen planus and systemic diseases may be coincidental, because (1) oral lichen planus is relatively common, (2) oral lichen planus occurs predominantly in older adults, and (3) many drugs used in the treatment of systemic diseases trigger the development of oral lichenoid lesions as an adverse effect. (medscape.com)
6 Treatment is identical to other cutaneous forms of LP. In localized cases, topical corticosteroids are considered first-line therapy, followed by narrowband ultraviolet B. There are numerous options for generalized or refractory cases, including systemic or intramuscular corticosteroids, plaquenil, dapsone, oral retinoids, or apremilast. (jcadonline.com)

The main sites are inner forearm, wrist, legs, ankles, and face.Lichen Planus affecting mucous membranes is termed Mucosal Lichen Planus. (homoeoonline.com)
In Mucosal Lichen Planus, the main presentation is white patches or white, lacy net-like pattern, ulcers or patches of irregular redness.Like for other skin disorders, Homeopathy is very effective as a remedy for Lichen Planus patients too. (homoeoonline.com)

The following five chapters encompass the application and role of skin biopsy to the overall diagnosis of certain conditions such as non-scarring and scarring alopecia, Langerhan cell neoplasms, severe cutaneous adverse reactions, pemphigus vulgaris and foliaceus, and oral lichen planus. (freebookcentre.net)

Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. (hindawi.com)
Lichen planus (LP) is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. (hindawi.com)
Planet Ayurveda offers herbal remedies that aim at removing the toxins in a natural way, controlling the inflammatory process thereby reducing itching, burning and further spread of the lichen spots. (247healthblog.com)
Although classic cutaneous LP (CCLP) and oral LP (OLP) are basically known as the different subtypes of the same disease sharing the common histopathological features, they actually have significant differences both in the clinical behavior and in the molecular inflammatory pathogenesis. (deu.edu.tr)
Lichen planus is a pruritic inflammatory dermatosis of unknown origin. (thedoctorsdoctor.com)
Lichen planus is a chronic inflammatory disease of unknown origin, which most commonly affects individuals between 30-60 years of age and is characterized by different types of lesions involving the skin and mucosa . (amboss.com)
Lichen sclerosus is a chronic inflammatory skin disorder that most commonly affects women before puberty or after menopause. (rarediseases.org)
Oral lichen planus and lichenoid reactions are autoimmune type inflammatory conditions of the oral mucosa with similar clinical and histological characteristics. (ecancer.org)
Lichen Planus is a chronic non-infectious inflammatory condition affecting the skin and mucous membranes inside the mouth.Lichen Planus is an autoimmune disorder. (homoeoonline.com)

Oral LP (OLP) can be the sole clinical presentation of the disease or accompanied by cutaneous or other mucosal manifestations including the genital area, gastrointestinal tract, and eyes. (hindawi.com)
In 1937, Guogerot and Burnier described the coexistence of oral, cervical, and stomach LP lesions with no cutaneous involvement as "plurimucosal LP" [ 9 ]. (hindawi.com)
Bettoli V, De Padova MP, Corazza M, Virgili A. Generalized lichen nitidus with oral and nail involvement in a child. (medscape.com)
Plaquelike oral lichen planus on the buccal mucosa on the left side. (medscape.com)
Ulcerative oral lichen planus on the dorsum of the tongue. (medscape.com)
The dense subepithelial mononuclear infiltrate in oral lichen planus is composed of T cells and macrophages, and there are increased numbers of intraepithelial T cells. (medscape.com)
Therefore, early in the formation of oral lichen planus lesions, CD8 + T cells may recognize an antigen associated with the major histocompatibility complex (MHC) class I on keratinocytes. (medscape.com)
Oral lichen planus lesions contain increased levels of the cytokine tumor necrosis factor (TNF)-alpha. (medscape.com)
[ 8 ] T cells in oral lichen planus contain mRNA for TNF and secrete TNF in vitro. (medscape.com)
[ 9 ] Serum and salivary TNF levels are elevated in oral lichen planus patients. (medscape.com)
Of possible significance, elevated concentrations of interleukin-6 (IL-6) and neopterin in saliva and serum of patients with the erosive-atrophic form of oral lichen planus suggest they may be involved in the etiology of this disease variation. (medscape.com)
[ 20 ] Additionally, microRNA 4484 (miR-4484) has been found to be significantly up-regulated in the salivary exosomes of patients with oral lichen planus. (medscape.com)
The role of autoimmunity in the pathogenesis is supported by many autoimmune features of oral lichen planus, including its chronicity, onset in adults, predilection for females, association with other autoimmune diseases, occasional tissue-type associations, depressed immune-suppressor activity in patients with oral lichen planus, and the presence of autocytotoxic T-cell clones in lichen planus lesions. (medscape.com)
Current data suggest that oral lichen planus (OLP) is a T-cell-mediated autoimmune disease in which autocytotoxic CD8 + T cells trigger the apoptosis of oral epithelial cells. (medscape.com)
However, the precise cause of oral lichen planus is unknown. (medscape.com)
Lichen planus and hepatitis C virus: a multicenter study of patients with oral lesions and a systematic review. (jcadonline.com)
Recent data suggest that oral lichenoid reactions (OLR) present a greater percentage of malignant transformation than oral lichen planus (OLP). (ecancer.org)
Oral lichen planus (OLP) is a relatively common mucocutaneous entity. (ecancer.org)
When the mucosal lining of mouth is involved, it is termed Oral Lichen Planus. (homoeoonline.com)
Oral Lichen Planus includes inner cheeks, lips, tongue and gums. (homoeoonline.com)
Among the bunch of natural remedies for Lichen Planus, Borax is most often used for Oral lichen. (homoeoonline.com)
Plantago is another natural medicine of great help in the treatment of Oral Lichen Planus. (homoeoonline.com)
The prevalence of oral lichen planus in the United States is unknown. (medscape.com)
Oral lichen planus affects approximately 1-2% of the general adult population, although the prevalence of the disease is unknown in many areas. (medscape.com)
[ 22 ] Oral lichen planus is a common noninfectious oral mucosal disorder among adult patients who attend oral pathology and oral medicine clinics. (medscape.com)
Oral lichen planus affects all racial groups. (medscape.com)
The female-to-male ratio for oral lichen planus is 1.4:1. (medscape.com)
Oral lichen planus predominantly occurs in adults older than 40 years, although younger adults and children can be affected. (medscape.com)
Shan J, Ma JM, Wang R, Liu QL, Fan Y. Proliferation and Apoptosis of Peripheral Blood Mononuclear Cells in Patients with Oral Lichen Planus. (medscape.com)

Lichen sclerosus overlap syndrome, sharing features of lichen planus and lichen sclerosus. (wikipedia.org)

Objectives Previous studies have shown that patients with lichen planus (LP) have an increased occurrence of inflammation-related dyslipidemia. (deu.edu.tr)
Cutaneous examination of patients with ESRD has shown that 50-100% of patients have at least 1 dermatologic condition. (medscape.com)
A high prevalence of cutaneous disorders is expected, because most patients with ESRD have an underlying disease process with cutaneous manifestations. (medscape.com)
Many cutaneous disorders experienced by patients undergoing dialysis have little to do with the uremic syndrome and are related to the same underlying pathologic process that caused the renal disease. (medscape.com)
Patients with lichen myxedematosus have a long-term, disfiguring, possibly disabling disorder. (medscape.com)
Glorioso S, Jackson SC, Kopel AJ, Lewis V, Nicotri T Jr. Actinic lichen nitidus in 3 African American patients. (medscape.com)
Coexistence of atopic dermatitis and lichen nitidus in three patients. (medscape.com)
A number of associated cutaneous findings have been reported in up to 15% of these patients including lichen planus-like eruptions (LP). (thedoctorsdoctor.com)
Cutaneous biopsies were performed on all patients. (thedoctorsdoctor.com)
Some patients with lichen sclerosus do not have any symptoms, whereas others experience intense itching, discomfort and/or erosions/ulcers. (rarediseases.org)
High prevalence of glucose metabolism disturbance in patients with lichen planus. (jcadonline.com)
Molecular and phenotypic spectrum of cardio-facio-cutaneous syndrome in Chinese patients. (cdc.gov)

Other variants may include: Lichen planus pemphigoides characterized by the development of tense blisters atop lesions of lichen planus or the development vesicles de novo on uninvolved skin. (wikipedia.org)

Hill TG, Crawford JN, Rogers CC. Successful management of lichen myxedematosus. (medscape.com)

A patient who is suffering from other skin conditions such as lichen planus, fungal infections or atopic dermatitis has higher chances of developing this condition. (247healthblog.com)

An increased prevalence of a wide range of liver disease in lichen planus has been observed by many authors. (thedoctorsdoctor.com)

The most common cutaneous presentation of secondary syphilis is a generalized morbilliform rash, usually involving the palms and soles. (ccjm.org)
Mucocutaneous candidiasis, including recurrent and widespread diaper dermatitis and chronic paronychia, is a common cutaneous manifestation in children with HIV infection. (medscape.com)
The most common cutaneous infections in children with HIV disease are impetigo and cellulitis caused by Staphylococcus aureus. (medscape.com)

The purpose of this article is to integrate renal and cutaneous aspects of disease as well as highlight some important, although frequently underappreciated, clinical or laboratory findings that ally renal and skin diseases. (medscape.com)
The term lichenoid reaction (lichenoid eruption or lichenoid lesion) refers to a lesion of similar or identical histopathologic and clinical appearance to lichen planus (i.e., an area which resembles lichen planus, both to the naked eye and under a microscope). (wikipedia.org)
Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. (jcadonline.com)
Weston G, Payette M. Update on lichen planus and clinical variants. (jcadonline.com)
This group of cutaneous disorders is thought to represent a clinical spectrum that most often starts as erythematous serpentine streaks precisely located over the injected veins, followed by hyperpigmentation [ 2 ]. (cdlib.org)
Clinical manifestations of chronic GVHD are similar to autoimmune collagen vascular disease and the two main types of cutaneous chronic GVHD are lichenoid and sclerodermatous. (bvsalud.org)

Hyperkeratotic and hypertrophic lichen nitidus. (medscape.com)

In addition, uremia and conditions associated with renal replacement therapy are fraught with numerous and, often, relatively unique cutaneous disorders. (medscape.com)
The image below illustrates several uremia-related cutaneous disorders. (medscape.com)
Several uremia-related cutaneous disorders are visible. (medscape.com)
Cutaneous manifestations of human immunodeficiency virus (HIV) disease may result from HIV infection itself or from opportunistic disorders secondary to the decline in immunocompetence from the disease. (medscape.com)
1] Cutaneous disorders may be the initial signs of HIV-related immunosuppression. (medscape.com)

Punch biopsy showed an effaced and markedly thinned epidermis with overlying compact hyperkeratosis, a band-like lymphocytic infiltrate filling the papillary dermis, and numerous colloid bodies and melanophages along the dermal-epidermal junction, all consistent with atrophic lichen planus (LP). The patent was started on topical corticosteroids and showed an improvement in his symptoms at his four-month follow-up appointment. (jcadonline.com)

Purpuric generalized lichen nitidus: an unusual eruption simulating pigmented purpuric dermatosis. (medscape.com)

Three cases of lichen nitidus associated with various cutaneous diseases. (medscape.com)
A variety of neoplastic, infectious, and noninfectious diseases can produce cutaneous manifestations throughout the course of HIV disease. (medscape.com)
Many diseases present with cutaneous annular lesions, making distinction by physical appearance alone challenging. (aafp.org)

Cutaneous forms are those affecting the skin, scalp, and nails. (wikipedia.org)
Lichen planus can affect the skin , mucosa , scalp, genitalia, and nails , and manifests with varying symptoms depending on the subtype of the disease. (amboss.com)

The specific antigen that triggers lichen planus is unknown, although it may be a self-peptide (or altered self-peptide), in which case lichen planus would be a true autoimmune disease. (medscape.com)

The expression or unmasking of the lichen planus antigen may be induced by drugs (lichenoid drug reaction), contact allergens in dental restorative materials or toothpastes (contact hypersensitivity reaction), mechanical trauma (Koebner phenomenon), viral infection, or other unidentified agents. (medscape.com)

Lichen planus associated with hepatitis C virus: No viral transcripts are found in the lichen planus, and effective therapy for hepatitis C virus does not clear lichen planus. (thedoctorsdoctor.com)

RÉSUMÉ Nous avons passé en revue les manifestations dermatologiques liées à l'infection chronique par le virus de l'hépatite C (VHC) et leur rapport avec l'état hépatique. (who.int)

Organisms1

Diseases8

Chemicals and Drugs1

Amyloidosis32

Lupus8

Planopilaris6

Papules7

Treatment of lichen3

Granuloma1

Psoriasis4

Pathogenesis of oral lichen2

Squamous5

Systemic5

Mucosal Lichen Planus2

Alopecia1

Inflammatory9

Oral29

Features of lichen1

Patients12

Lesions of lichen1

Management of lichen1

Atopic dermatitis1

Prevalence1

Common cutaneous3

Clinical6

Hypertrophic1

Disorders5

Dermal-epidermal junction1

Eruption1

Diseases3

Scalp2

Autoimmune1

Lichenoid drug1

Hepatitis C vir1

Manifestations1