• At 5 years there was no longer any significant difference for clinical and radiographic outcomes between treatment strategies applied during the first 2 years. (bmj.com)
  • Childhood-onset schizophrenia is a severe form of psychotic disorder that occurs at age 12 years or younger and is often chronic and persistently debilitating, with worse outcomes than patients who have later onset of symptoms. (medscape.com)
  • They instead suggested a cut-off age of 14.7 years of age based on higher levels of positive symptoms and poorer psychosocial functioning under this cut-off and better outcomes over this cut-off. (medscape.com)
  • The aim of this study is to evaluate the 2-years outcomes of repetitive doses of the transvaginal pudendal nerve injections (PNI) and to compare the success of the PNI concerning anatomical levels (endopelvic and extrapelvic portion) of the pudendal nerve pathology. (researchsquare.com)
  • We have been interested in the publication by Möttönen and colleagues concerning the outcome of patients with early rheumatoid arthritis (RA) who have been treated actively by disease suppressing drugs using a "sawtooth" strategy 1 , 2 and have assessed the outcomes in our patients with early RA who have been treated using a similar strategy. (bmj.com)
  • The use of nutritional ERPs may enhance short-term and long-term recovery and mitigate frailty progression while improving patient-reported outcomes. (bmj.com)
  • Data gathered from the PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery Study will be published in peer-reviewed journals and presented at national and international conferences. (bmj.com)
  • secondary outcomes included evaluation of changes in Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, tear film break-up time (TBUT), corneal and conjunctival staining, tear osmolarity, matrix metalloproteinase-9 (MMP-9), artificial tear use and safety assessments. (springer.com)
  • The surgical duration and patient-reported outcomes (visual analog scale for discomfort) will be documented. (biomedcentral.com)
  • The secondary outcomes are inferior scapular notching, patient-reported and functional outcomes (Oxford shoulder score, Constant-Murley score and pain), side effects and complications, changes in bone mineral density and economy. (lu.se)
  • BACKGROUND: Locoregional therapies (LRTs) are commonly used to increase the number of potential candidates for liver transplantation (LT). The aim of this paper is to assess the outcomes of LRTs prior to LT in patients with hepatocellular carcinoma (HCC) beyond the listing criteria. (bvsalud.org)
  • We included papers assessing adult patients with HCC considered for LT and reporting intention-to-treat (ITT) survival outcomes. (bvsalud.org)
  • INTRODUCTION: Locoregional therapies are commonly used as bridging strategies to decrease the drop-out of patients with hepatocellular carcinoma (HCC) awaiting liver transplantation (LT). The present paper aims to assess the outcomes of bridging therapies in patients with HCC considered for LT according to an intention-to-treat (ITT) survival analysis. (bvsalud.org)
  • Papers assessing adult patients with HCC considered for LT and reporting ITT survival outcomes were included. (bvsalud.org)
  • Outcomes following liver transplantation improved dramatically for patients with HCC following the implementation of the Milan criteria in the late 1990s. (hindawi.com)
  • Ever since, the rather restrictive nature of the Milan criteria has been challenged with good outcomes. (hindawi.com)
  • Although the event rates for both the primary and secondary outcomes were nearly identical with the two antiplatelet regimens, the trial failed to meet the non-inferiority criteria. (webwire.com)
  • Tools that can facilitate patient-provider interaction around dDPPs may contribute to improved patient engagement and adherence to these programs and improved health outcomes. (researchprotocols.org)
  • Secondary outcomes will be patient engagement (use and activity) in the dDPP. (researchprotocols.org)
  • modify the patient's beliefs and consider patient's characteristics (21/25 statements) to influence patient outcomes during chronic LBP rehabilitation. (biomedcentral.com)
  • All five CF domains were perceived as capable of influencing patient outcomes, with the patient-practitioner relationship being perceived as the most important CF during routine clinical practice. (biomedcentral.com)
  • The objective of this study was to identify and compare predictors of three relevant outcomes of chronic arthritis in a cohort of very early arthritis patients. (biomedcentral.com)
  • Logistic regression analyses were performed to determine independent predictors of three outcomes: persistent synovitis, prescription of disease-modifying anti-rheumatic drugs (DMARDs), and established clinical RA diagnosis within one year. (biomedcentral.com)
  • Positive ACPA status and small joint arthritis were consistent predictors of three relevant outcomes of chronic arthritis in very early arthritis patients. (biomedcentral.com)
  • For highly selected patients with early stage (≤3 cm), unresectable hilar cholangiocarcinoma or cholangiocarcinoma arising in the setting of primary sclerosing cholangitis, the sequential combination of high-dose neoadjuvant radiotherapy with chemosensitization, brachytherapy, maintenance chemotherapy, and orthotopic liver transplantation achieves excellent outcomes, with a 65% rate of recurrence-free survival after 5 years. (medscape.com)
  • However, the efficacy of the PNIs declined over two years. (researchsquare.com)
  • In recent years, 2 enhanced IIVs, MF59-adjuvanted standard-dose IIV and a high-dose IIV that contains 4 times the hemagglutinin antigen of each virus compared with the standard-dose IIV, have been developed to improve the immune responses to and efficacy of standard-dose IIVs ( 15 , 16 ). (cdc.gov)
  • High-dose IIV has also met prespecified criteria for superior efficacy against laboratory-confirmed influenza compared with standard-dose IIV ( 15 , 17 ). (cdc.gov)
  • This study will seek to investigate the efficacy of "Microbiota modulation of the Gut-Lung Axis" combined with chemotherapy in patients with advanced NSCLC. (biomedcentral.com)
  • Based on the theoretical basis of "intestinal and lung axis microecological adjustment", combined with traditional platinum-containing two-drug chemotherapy, the efficacy of the new therapy on patients with advanced NSCLC was observed. (biomedcentral.com)
  • We aim to compare two different doses of dexamethasone in patients with moderate to severe ARDS undergoing mechanical ventilation regarding efficacy and safety. (biomedcentral.com)
  • The primary efficacy criterion will be the change in Movement Disorders Society-Unified Parkinson's Disease-Rating Scale Part I score between baseline (i.e. randomization) and week 4. (springer.com)
  • This study should be the basis for further evaluations of long-term efficacy and safety of the use of cannabinoids in PD patients. (springer.com)
  • To evaluate the safety and efficacy of abatacept plus methotrexate (MTX) over 5 years in patients with rheumatoid arthritis. (jrheum.org)
  • We describe safety analyses for all patients who received at least 1 dose of abatacept and efficacy analyses for the original ~10 mg/kg abatacept-treated group, over 5 years. (jrheum.org)
  • Abatacept maintained the efficacy observed at Year 1 over 5 years of treatment, and demonstrated consistent safety and tolerability. (jrheum.org)
  • This Phase IIb study demonstrated the safety and efficacy of abatacept plus methotrexate (MTX) over 1 year of double-blind (DB) treatment in patients with RA and an inadequate response to MTX 3 , 4 , and confirmed ~10 mg/kg to be the most effective dose. (jrheum.org)
  • Subsequent Phase III studies verified the efficacy and safety of abatacept both in patients with an inadequate response to MTX 5 and in patients with an inadequate response to anti-TNF agents 6 . (jrheum.org)
  • We describe the safety, tolerability, and efficacy of abatacept ~10 mg/kg over 5 years of treatment in the continuing open-label longterm extension (LTE) of a Phase IIb study. (jrheum.org)
  • We report on the safety and tolerability of all patients who received at least 1 dose of abatacept over 5 years, and the efficacy and health-related quality of life (HRQOL) of patients who had received ~10 mg/kg abatacept over 5 years in this continuing open-label extension of a Phase IIb study. (jrheum.org)
  • Stroke is the third leading cause of death in developed countries after coronary heart disease and cancer.4 Patients who survive a first stroke are at a high risk of a first recurrent stroke.5 PRoFESS is the first trial to directly compare the efficacy and safety of the two antiplatelet agents, ER-DP plus aspirin and clopidogrel, in the prevention of recurrent stroke after non-cardioembolic ischaemic stroke. (webwire.com)
  • The mediator variables (self-efficacy, digital health literacy, and patient-provider relationship) will be measured. (researchprotocols.org)
  • Patients who are seen in clinical practice commonly have multiple problems, yet efficacy data often reflect treatment of a single illness. (psychiatrictimes.com)
  • Thus, shared decision making and patient preferences are central to care models that can improve efficacy, patient and clinician satisfaction, and help reduce health disparities. (ahrq.gov)
  • Methods Clinical and radiographic 5-year outcome was compared between initial strategies. (bmj.com)
  • Material and Methods: It was conducted in a population of 168 students between 6-12 years old in concerted Azalea Beniel School. (isciii.es)
  • The objective of this document is to outline the available methods and tools for screening and sequencing patient specimens for the detection of VOC or VOI, with a focus on those that offer a rapid turn-around time so as to support rapid implementation of public health actions for COVID 19 control. (who.int)
  • However, none of the studied therapies (including CBT) "fulfilled the criteria for empirically supported treatment. (wikipedia.org)
  • Although data exist on the prevalence of some immunosuppressive conditions, the total burden of these conditions in the United States remains unknown, particularly when considering patients who are receiving emerging immunosuppressive therapies ( 6 - 8 ). (cdc.gov)
  • Enrollees also know they are helping mankind develop new therapies for future generations of patients. (gacancer.com)
  • Results presented showed that in the SETTLE study safinamide significantly improved 'super responder' rates in fluctuating PD patients as add-on to levodopa and other dopaminergic therapies. (news-medical.net)
  • Safinamide was also associated with clinically important improvement in motor symptoms in fluctuating PD patients as add-on to levodopa and other dopaminergic therapies. (news-medical.net)
  • These include evaluation of extended criteria, the use of bridging therapies while patients are awaiting a transplant, the concept of allocation and prioritising, the use of living related donor transplants, the implications of using marginal grafts for HCC, and the role of downstaging therapies. (hindawi.com)
  • Despite significant progress in the pathophysiology of AR and BA and availability of several therapies in recent years, a true and complete cure for these two so far seems out of reach 1 . (ijpsr.com)
  • Multiple regression analysis showed that early response to treatment is an independent predictor of 5-year outcome, irrespective of treatment strategy. (bmj.com)
  • Good-response to treatment independently predicts significantly better 5-year clinical and radiographic outcome. (bmj.com)
  • 9 Disease activity during the first 3 months of treatment has been related to clinical and radiographic outcome after the first year of treatment, 6 10 11 and an early treatment response can predict the long-term work disability outcome. (bmj.com)
  • The present study investigates 5-year data of a 2-year methotrexate (MTX) based tight control treatment (TC) strategy compared to conventional MTX-based treatment (CT) strategy, and the (added) predictive value of an early response (at 6 months) to treatment for 5-year outcome with respect to disease activity and radiographic progression. (bmj.com)
  • ABSTRACT We evaluated the prevalence of diabetes comorbidity in Greek psychiatric patients, differences between type 1 and type 2 diabetics and the outcome of psychiatric disorder. (who.int)
  • Existence of diabetes mellitus (regardless of type), duration of untreated mental illness and lack of patient therapeutic education were negative predictors of (unfavourable) outcome. (who.int)
  • These findings provide evidence of a high prevalence of diabetes in psychiatric patients and that having diabetes has an adverse effect on outcome of psychiatric illness. (who.int)
  • The 28% remission rate noted in our patients at two years is very similar to the 27% noted by Möttönen and colleagues after two year of treatment suggesting that this figure could be used as a standard for those auditing the outcome of the management of early RA by different rheumatology centres. (bmj.com)
  • 1996 ) Outcome of patients with early rheumatoid arthritis treated according to the "sawtooth" strategy. (bmj.com)
  • We wish to thank Dr Teir and colleagues for the comments and their data concerning the outcome of patients with early rheumatoid arthritis (RA). (bmj.com)
  • We hypothesize that the lateralization improves the patient outcome by decreasing the risk of inferior scapular notching without increasing the risk of migration and loosening of glenoid component. (lu.se)
  • This study intends to determine which treatment has the most optimal outcome for the benefit of future patients with an indication for reverse shoulder arthroplasty. (lu.se)
  • A total of 38 patients will have 80% power to detect a probability of 0.231 that an observation in the treatment group is less than an observation in the placebo group using a Wilcoxon rank-sum test with a 0.050 two-sided significance level assuming a true difference of 2.5 points between nabilone and placebo in the primary outcome measure and a standard deviation of the change of 2.4 points. (springer.com)
  • Outcome measures were assessed and analyzed after one year. (ijpsr.com)
  • Impaired neck movement was related to poor outcome after 1 year. (painstudy.ru)
  • To evaluate the association between the outcome and patient variables was applied Cox regression test. (bvsalud.org)
  • From primary data collected from patients enrolled in a referral hospital for the care of women and adolescents victims of sexual violence and legal termination of pregnancy, with the outcome variable analyzed as abortion, logistic regression was applied and the use of stepwise backward method observed that where only when the sex offender is typified as known explains the withdrawal of the procedure. (bvsalud.org)
  • Subjective global assessment of change in elbow symptoms, patient-rated tennis elbow evaluation, visual analogue pain at rest, visual analogue pain with activity, visual analogue pain intensity, grip strength, and strength testing using the Orthopaedic Research Institute-Tennis Elbow Testing System. (bmj.com)
  • The American Academy of Neurology no longer recommends syphilis screening in the routine evaluation of dementia if patients come from geographic regions with a very low base rate of syphilis. (medscape.com)
  • Patients who participated in the Computer Assisted Management in Early Rheumatoid Arthritis (CAMERA 12 ) trial were evaluated. (bmj.com)
  • 1998 ) Only high disease activity and postive rheumatoid factor indicate poor prognosis in patients with early rheumatoid arthritis treated with "sawtooth" strategy. (bmj.com)
  • The current 1987 American College of Rheumatology (ACR) classification criteria for rheumatoid arthritis (RA) have proven less useful in early arthritis. (biomedcentral.com)
  • The study cohort included 25 adult patients (50 surgery sites) recruited from Peking University Hospital and School of Stomatology who met the inclusion criteria. (biomedcentral.com)
  • REMED is a prospective, open-label, randomised controlled trial testing the superiority of dexamethasone 20 mg (dexamethasone 20 mg on days 1-5, followed by dexamethasone 10 mg on days 6-10) vs 6 mg administered once daily intravenously for 10 days in adult patients with moderate or severe ARDS due to confirmed COVID-19. (biomedcentral.com)
  • Private practice patients: 154 adult patients with chronic lateral epicondylosis were recruited, with 136 patients completing the trial. (bmj.com)
  • The Norwegian Very Early Arthritis Cohort (NOR-VEAC) includes adult patients with at least one swollen joint of ≤16 weeks' duration. (biomedcentral.com)
  • 66 patients with the chronic fatigue syndrome who had neither a psychiatric disorder nor appreciable sleep disturbance. (bmj.com)
  • These findings support the use of appropriately prescribed graded aerobic exercise in the management of patients with the chronic fatigue syndrome. (bmj.com)
  • Patients with the chronic fatigue syndrome perceive greater fatigue than healthy controls taking the same exercise. (bmj.com)
  • 10 Fitness training improved both aerobic capacity and myalgia more than flexibility exercises in patients with the "fibrositis/fibromyalgia syndrome," 13 a condition which overlaps with the chronic fatigue syndrome. (bmj.com)
  • Patients met the Oxford criteria for the chronic fatigue syndrome. (bmj.com)
  • Data suggest that classical homeopathic treatment may be a useful measure for the patients suffering from chronic AR. (ijpsr.com)
  • In this cohort of primary care patients with predominantly subacute or chronic ACJ pain of non-traumatic onset, traditional ACJ tests were of limited diagnostic value. (biomedcentral.com)
  • Drawing on a panel of United Kingdom practitioners' expertise, this study aimed to investigate their perceptions of CFs during the management of patients presenting with chronic low back pain (LBP). (biomedcentral.com)
  • A modified two-round online Delphi-consensus survey was conducted to measure the extent of panel agreement regarding the perceived acceptability and influence of five main types of CFs during clinical management of patients with chronic LBP. (biomedcentral.com)
  • Qualified musculoskeletal practitioners in the United Kingdom providing regular treatment for patients with chronic LBP were invited to take part. (biomedcentral.com)
  • Musculoskeletal practitioners may require further training to enhance their proficiency and confidence in applying essential psychosocial skills to address the complex needs of patients with chronic LBP. (biomedcentral.com)
  • The rationale behind this approach is derived from the hypothesis that the physician at the time of a disease-modifying anti-rheumatic drug (DMARD) prescription assumes the patient to be at high risk of developing chronic and severe disease. (biomedcentral.com)
  • it applies principles of the chronic care model, including community-clinic linkages, to the management of patients newly diagnosed with diabetes and prediabetes through screening. (cdc.gov)
  • Because more than 80% of PDAC is locally advanced unresectable or metastatic at the time of diagnosis [ 2 ], the prognosis of PDAC patients is dismal with a 5-year relative survival rate of 11.4% [ 3 ]. (jcancer.org)
  • Prognosis was worsened in a Swiss study in patients with previously known neck pain, tension-type headache or migraine. (painstudy.ru)
  • Nevertheless, the criteria have been widely used in the clinical setting, even in the assessment of patients with recent-onset arthritis, and it can be assumed that rheumatologists often consider the fulfilment of these criteria when evaluating the diagnosis and/or prognosis in their arthritis patients [ 6 ]. (biomedcentral.com)
  • Two clinical experts will independently screen the studies for inclusion using eligibility criteria established a priori . (biomedcentral.com)
  • then thirty four consenting patients were enrolled after screening of 58 patients by eligibility criteria and were allocated to classical homeopathic treatment. (ijpsr.com)
  • 50 nmol/L). The primary objective is to determine whether the dosing protocol normalizes vitamin D status, defined as a blood total 25(OH)D concentration above 75 nmol/L. Secondary objectives include an examination of the safety of the dosing regimen (e.g. hypercalcemia, hypercalciuria, nephrocalcinosis), measures of vitamin D axis function (e.g. calcitriol levels, immune function), and protocol feasibility (eligibility criteria, protocol deviations, blinding). (biomedcentral.com)
  • RÉSUMÉ Nous avons évalué la prévalence de la comorbidité du diabète chez des patients grecs atteints de troubles psychiatriques, les différences entre les diabétiques de type 1 et de type 2 et l'évolution des troubles psychiatriques. (who.int)
  • The first five years in schizophrenia evolution are considered the most important and throughout this perspective, early and sustained interventions are a major objective for these patients well-being. (romjpsychiat.ro)
  • This will facilitate patient engagement in digital behavior change interventions and provider engagement in patients' use of dDPPs. (researchprotocols.org)
  • Depression and alcoholism treatment requires the proper use of medication and psychosocial interventions, as well as a solid doctor-patient relationship and a commitment to treat both disorders. (psychiatrictimes.com)
  • Virtual health technologies, also considered telehealth services, may include mobile health applications (apps) or devices that collect patient-generated health data and interventions provided over the internet, such as screening questionnaires and education. (ahrq.gov)
  • Screening high-risk patients to detect diabetes and prediabetes was cost-effective (7-9), and prevention of type 2 diabetes in people with prediabetes through adoption of appropriate lifestyle changes and pharmacologic interventions has been successful in experimental settings (10). (cdc.gov)
  • DSM-5 diagnostic criteria for schizophrenia requires at least two of the following five symptoms to be present for a month. (medscape.com)
  • In patients with a history of autism spectrum disorder or a communication disorder of childhood onset, the additional diagnosis of schizophrenia is made only if prominent delusions or hallucinations, in addition to the other required symptoms or schizophrenia are also present for at least 1 month (or less if successfully treated). (medscape.com)
  • One study on the validity of a diagnosis of early-onset schizophrenia in Denmark found a correspondence of 88.8%, comparing the diagnosis listed in the Denmark registry to a clinical diagnosis based on symptoms reported in patient records. (medscape.com)
  • Ravi Anand, Newron's CMO, stated: 'The results presented indicate a magnitude of benefit with safinamide which is of clinical relevance, i.e. improvements of more than one hour in the patient and caregiver-rated ON and OFF time plus 30 per cent or greater improvement in motor symptoms (UPDRS Part III, as rated by a neurologist) in a significantly super responders' and have not been observed with other treatments to date. (news-medical.net)
  • The responder rate analysis using multiple and combined criteria show compelling evidence that a substantial proportion of Parkinson's disease patients, even in advanced stage treated with safinamide obtain significant clinical benefits in all major motor symptoms thus significantly improving their quality of life', said Marco Sardina, Zambon's CSO. (news-medical.net)
  • Although open-label observations report a positive effect of cannabinoids on non-motor symptoms (NMS) in Parkinson's disease (PD) patients, these effects remain to be investigated in a controlled trial for a broader use in NMS in PD patients. (springer.com)
  • 14 A similar training programme improved symptoms and physiological findings in an open study of patients with the "effort syndrome. (bmj.com)
  • The first phase, funded by the R61, will provide funding for up to 3 years to develop quantitative measures that can differentiate abnormal myofascial tissue from healthy tissues using cross-sectional correlations with clinical signs/symptoms. (nih.gov)
  • AR may be intermittent with symptoms occurring on less than 4 days out of 7 or for less than 4 weeks per year or persistent with symptoms occurring on at least 4 days out of 7 or for more than 4 weeks per year 5, 7 . (ijpsr.com)
  • These studies focus on factors patient-dependent and are targeting the predictive value of positive symptoms, insight and social abilities. (romjpsychiat.ro)
  • In a small but substantial number of patients, grief may become persistent and disabling. (msdmanuals.com)
  • However, those individuals meeting the criteria for catatonia would receive an additional diagnosis of catatonia associated with schizophrenia to indicate the presence of the comorbidity. (medscape.com)
  • The validity of a diagnosis of childhood-onset schizophrenia has been a point of concern for some, due to difficulty in differentiating pediatric patients' reports of visual hallucinations from imaginary figures (which may be developmentally normal). (medscape.com)
  • Difficulties encountered in the treatment of patients suffering from PN are usually a result of its delayed diagnosis. (researchsquare.com)
  • Background The Harrogate and District Hospital Health and Wellbeing Project has successfully delivered education programmes to patients living with and beyond a cancer diagnosis. (bmj.com)
  • In 2018 the Palliative Care Team (PCT) was approached to develop a programme with focus on patients with a palliative diagnosis and their carers. (bmj.com)
  • The model has the potential to be developed for patients with a non-malignant diagnosis. (bmj.com)
  • An ongoing European League Against Rheumatism (EULAR)/ACR task force aims to define a set of criteria for the diagnosis of early RA [ 13 ]. (biomedcentral.com)
  • In patients with newly diagnosed dementia, obtain neuroimaging studies (ie, CT scanning or MRI of the head) to rule out treatable causes of dementia and to aid in the differential diagnosis. (medscape.com)
  • Diagnosis is by clinical criteria. (msdmanuals.com)
  • Infection with human papillomavirus increases the probability of developing carcinoma of the cervix, which is the second leading cause of cancer- related mortality in females worldwide, killing some 240 000 women per year.1 Making a correct diagnosis of a sexually transmitted infection is essential for the provision of appropriate and effective treatment. (who.int)
  • The study of malocclusions and their etiology is of fundamental importance to dentists who can prevent and/ or intercept problems that are difficult to solve in the long term through early diagnosis and preventive measures, and by increasing patients and/or guardians' awareness of the problem 6 . (bvsalud.org)
  • RESULTS: The literature search yielded 3,106 records, of which 11 papers (1874 patients) met the inclusion criteria. (bvsalud.org)
  • This retrospective longitudinal cohort study consists of patients with PN diagnosed with the first four essential Nantes criteria. (researchsquare.com)
  • This prospective population-based cohort study included all 98,551 individuals who in 2010 turned 65 years, lived in Sweden, and were in paid work at some point when aged 60-64. (biomedcentral.com)
  • In addition to the five symptom domain areas identified in the diagnostic criteria, the assessment of cognition, depression, and mania symptom domains is vital for making critically important distinctions between schizophrenia and other psychotic disorders. (medscape.com)
  • Within the included samples the average age was 13 years at referral, 15 years at assessment. (plos.org)
  • At the conclusion of the session, the participant will be able to describe Diagnostic and Statistical Manual of Mental Disorders 5th edition , DSM-5 assessment criteria for opioid use disorder, discuss the evidence for opioid use disorder medication assisted treatment with types of medications and settings used in medication assisted therapy. (cdc.gov)
  • Draft Summary of Product Characteristics (SmPC), Patient Information Leaflet (PIL) and labels should be included as prepared using the format provided in the medicines section of the WHO prequalification website (under WHO Public Assessment Reports). (who.int)
  • After the drop-outs, further analyses were carried out with a total of 56 patients. (researchsquare.com)
  • Several random controlled trials comparing DBT to other forms of cognitive-behavioral treatments have favored the use of DBT to treat borderline patients. (wikipedia.org)
  • The exclusion criteria are as follows: below 50 years of age, cognitive or linguistic impairment, insufficient glenoid bone stock, previous fracture in the upper extremity and autoimmune-mediated inflammatory arthritis. (lu.se)
  • Most studies evaluating therapeutic alliance were conducted in standardized therapeutic programs, which include cognitive-behavior therapy (CBT) and recovery- oriented cognitive therapy (CT-R) (5, 6, 7), and they investigated patients with a long history of disease. (romjpsychiat.ro)
  • The patient-practitioner relationship was rated as the most important CF, although the panel were not entirely confident in managing a range of patients' cognitive and emotional needs. (biomedcentral.com)
  • Conclusions The difference in disease activity between treatment strategies disappeared over the years. (bmj.com)
  • This treatment should begin within the school years, focusing on different areas of activity, especially Physical Education. (isciii.es)
  • There has traditionally been skepticism about the psychological treatment of personality disorders, but several specific types of psychotherapy for BPD have developed in recent years. (wikipedia.org)
  • The treatment emphasizes balancing acceptance and change (hence dialectic), with the overall goal of helping patients not just survive but build a life worth living. (wikipedia.org)
  • There were no significant clinical differences in the baseline measurements of disease severity or activity between those patients who subsequently developed remission with drug treatment and those who did not improve. (bmj.com)
  • In conclusion, the most common cause for failing to respond to a regimen of treatment of early RA patients within two years is lack of tolerance to the disease suppressing drug regimen. (bmj.com)
  • Despite the observed seemingly high remission rates it is clear that the results obtained with these treatment modalities do not satisfy all the RA patients, especially those with most severe disease and we have to develop more effective strategies to treat RA patients. (bmj.com)
  • Cytotoxic chemotherapy drugs have become the main treatment in recent decades, especially in patients with NSCLC without EGFR, ALK, and ROS gene mutations. (biomedcentral.com)
  • This study explores the combination of intestinal microecological regulation and chemotherapy to provide new treatment strategies and basis for lung cancer patients. (biomedcentral.com)
  • Patients will be randomised in a 1:1 ratio into one of the two treatment arms. (biomedcentral.com)
  • palliative treatment or best supportive care and likely to be in the last year of life. (bmj.com)
  • Patients who were experiencing a minimum of one and a half hours of 'OFF' time during the day were randomized equally to treatment with once a day safinamide (50-100mg) or placebo (standard of care including levodopa), as adjunctive treatment. (news-medical.net)
  • Again this year, SMRI is offering assistance for treatment trial applicants. (stanleyresearch.org)
  • Despite increasing awareness in recent years, NMS in PD are still frequently missed or undeclared during routine consultations and well-performed large-scale randomized controlled trials (RCTs) for the treatment of the different NMS in PD are lacking (Schrag et al. (springer.com)
  • Four patients receiving exercise and three receiving flexibility treatment dropped out before completion. (bmj.com)
  • 16 of 29 patients rated themselves as better after completing exercise treatment compared with eight of 30 patients who completed flexibility treatment. (bmj.com)
  • 12 of 22 patients who crossed over to exercise after flexibility treatment rated themselves as better after completing exercise treatment. (bmj.com)
  • 32 of 47 patients rated themselves as better three months after completing supervised exercise treatment. (bmj.com)
  • 35 of 47 patients rated themselves as better one year after completing supervised exercise treatment. (bmj.com)
  • 1. To estimate the treatment adherence and completion rates among confirmed tuberculosis patients. (who.int)
  • Unfortunately due to either tumour stage, size, and/or anatomy, patient comorbidities, or shortage of donor livers from both cadaveric and living donors, only 20% of patients undergo curative treatment [ 6 , 7 ]. (hindawi.com)
  • The purpose of this review is to provide an update on the current role of transplantation in the treatment of HCC and the strategies employed to increase the donor pool, improve the overall survival of patients on the transplant register, and reduce the number of patients dropping out of the waiting lists. (hindawi.com)
  • The recovery of menstrual function in adolescent patients with AN should be a major treatment goal to prevent severe long-term physical and psychological sequelae. (biomedcentral.com)
  • Given the high prevalence of stroke and recurrent stroke in aging societies, physicians need a range of treatment options so they can offer patients a regimen tailored to their individual needs. (webwire.com)
  • Landmark trials like PRoFESS help clinicians make evidence-based treatment choices and ensure that patients receive optimal therapy for their condition, said Professor Hans-Christoph Diener, MD, University of Essen, Germany, one of the three principal investigators of the study. (webwire.com)
  • Therapeutic alliance is consider an important therapeutic factor for both the involvement of patients, but also for the success of the therapeutic program itself, which is explained by a reduced severity in symptomatology, a better treatment compliance, low rates of drop-out and fewer hospitalizations (3, 4). (romjpsychiat.ro)
  • These CFs (i.e., the patient-practitioner relationship, patient's and practitioner's beliefs/characteristics, treatment characteristics, and environment) have not been widely evaluated by musculoskeletal practitioners. (biomedcentral.com)
  • Evidence from clinical treatment trials and changes made in the delivery of treatment from inpatient to outpatient settings bring into question the long-held view that patients with co-occurring depression and alcohol dependence must achieve abstinence from alcohol before treatment of depression can begin. (psychiatrictimes.com)
  • It was postulated that there were links between all three categories in etiology and also treatment, i.e., if the patient is treated for GPPPD, there might be an improvement in FSIAD and vice versa [ 6 ]. (biomedcentral.com)
  • However, conjugated estrogens vaginal cream is not available in Thailand, driving patients and physicians to seek alternative treatment for GSM. (biomedcentral.com)
  • 98 patients (25.5%) had persistent synovitis, 106 (27.6%) had received DMARD treatment during follow-up, while 68 (17.7%) were diagnosed with RA. (biomedcentral.com)
  • Features such as erosions and rheumatoid nodules reflect established disease and their value as part of the criteria is questioned in the era of early aggressive treatment, when the aim is to treat patients before bone damage occurs. (biomedcentral.com)
  • Patients with confirmed metastasis to N2 nodal stations (para-aortic, celiac, or superior mesenteric artery) do not benefit from radical resection and should receive systemic and/or palliative treatment. (medscape.com)
  • One study of 88 patients found the age cut-off of 12 years old to lack utility. (medscape.com)
  • Our study is prospective for five years and started in 1996. (bmj.com)
  • Clinical effectiveness data are sparse, but a recent observational study demonstrated lower vaccine effectiveness against influenza illness (≈20%) in patients with cancer compared with the general population (≈42%) ( 12 , 13 ). (cdc.gov)
  • With studies showing nearly 70% of potential patients live more than two hours away from the nearest study center, common sense suggests offering remote, yet meaningful, ways to participate will grow the trial patient population. (acrpnet.org)
  • During this new techXpo session, Kundert and Rangel will provide guidance on selecting a telemedicine provider and how VirTrial can help your site improve patient engagement, protocol compliance, and study retention. (acrpnet.org)
  • Headache and neck pain had totally disappeared after 20 days in Lithuania (4), whereas a Swiss study (7) reported neck pain in 25% after two years follow-up. (painstudy.ru)
  • A minor group who did not recover had, however significantly reduced neck mobility throughout the observation time, and this study shows that whiplash injured persons with reduced cervical- range-of-motion are at risk for long-term disability with a high sensitivity and persons exposed to whiplash injury with initial normal neck mobility almost all recover within one year. (painstudy.ru)
  • All patients who completed the 1-year, DB period of this study (clinical trial registration number: NCT00254293) 3 , 4 were eligible to enter the open-label LTE period. (jrheum.org)
  • This study aims to use a rigorous, user-centered design (UCD) methodology to develop a theory-driven system that supports patient engagement with dDPPs and their primary care providers with their care. (researchprotocols.org)
  • In this study design, investigators find a group of initially healthy people, record information about them (in this case what they eat), and watch who gets sick over the years. (blogspot.com)
  • Results 5 years of data were available for 205 of 299 patients, with no indication for selective drop-out. (bmj.com)
  • will allow obtaining results with 194 patients recruited. (bmj.com)
  • Analysis by intention to treat gave similar results (17/33 v 9/33 patients better). (bmj.com)
  • Patients with suggestive results in CBNAAT of pulmonary tuberculosis. (who.int)
  • These tests may be given to your child once or twice a year and the results are given in what we call percentiles. (naset.org)
  • The results are partially contradictory, as regarding the severity of positive symptomatology, which correlates negative, in some studies, with how the therapeutic alliance is perceived by the patient, while in others they do not (5, 8, 9). (romjpsychiat.ro)
  • The same contradictory results appear when the patient, and also the therapist opinion on the quality of therapeutic relationship were investigated. (romjpsychiat.ro)
  • As of December 2020, 27 patients have been enrolled and first results are expected to be submitted for publication in early 2021. (researchprotocols.org)
  • In recent years, GD diagnoses have been increasingly made in child and adolescent services [ 2 - 4 ]. (plos.org)
  • The patients had a range of diagnoses. (bmj.com)
  • To the best of our knowledge, there are no studies that have examined the association between sickness absence (SA) or disability pension (DP) due to mental diagnoses in the years leading up to the standard retirement age of 65 and being in paid work after 65. (biomedcentral.com)
  • 10 Data were collected on a sample of 43,093 adults (18 years and older) who were interviewed between 2001 and 2002 to determine lifetime and current (past 12 months) DSM-IV diagnoses. (psychiatrictimes.com)
  • In fact though, involving patients with schizophrenia spectrum disorders and maintaining them in therapy is a real challenge, and this process has often a high rate of abandonment, followed shortly by relapse (1, 2). (romjpsychiat.ro)
  • 0.015) and the duration of untreated mental illness was shorter (mean 2.86, SD 3.06 years compared with mean 4.13, SD 6.24 years for type 2 diabetics). (who.int)
  • It enrolled 549 patients with mid-to late-stage idiopathic Parkinson's disease (more than three years of disease duration) treated with optimized, stable doses of levodopa and standard of care (dopamine agonist, COMT inhibitor, anticholinergic and/or amantadine) for at least four weeks. (news-medical.net)
  • 6 - 8 The duration of the average episode is estimated to be between 6 months and 2 years, 9 with 83% of patients either "completely recovered" or "much improved" within 12 months with a wait-and-see policy. (bmj.com)
  • Whiplash injured patients had significantly higher scores on both intensity and quality of cold-induced pain and shorter duration regarding time of immersion in cold water compared with healthy controls (10). (painstudy.ru)
  • Of 384 patients eligible for one year follow-up (56.3% females, mean (SD) age 45.8 (14.7) years, median (IQR) duration of arthritis 31 (10-62) days), 14.4% were anti-CCP2 positive, and 11.2% were IgM RF positive. (biomedcentral.com)
  • Recent estimates of the co-occurrence of these disorders in the general population are derived from the National Epidemiologic Survey on Alcohol and Related Conditions , a large-scale, nationally representative survey using DSM-IV diagnostic criteria. (psychiatrictimes.com)
  • Importantly, this surrogate is used in ongoing efforts to develop new diagnostic criteria for early RA. (biomedcentral.com)
  • Specifically, DBT has been found to significantly reduce self-injury, suicidal behavior, impulsivity, self-rated anger and the use of crisis services among borderline patients. (wikipedia.org)
  • Digital diabetes prevention programs (dDPPs) are effective behavior change tools to prevent disease progression in patients at risk for diabetes. (researchprotocols.org)
  • Nonpharmacologic strategies may help with behavior problems in patients with vascular dementia. (medscape.com)
  • At two years 14 patients were in remission, nine patients showed partial improvement but were not in remission, 21 subjects have not shown an over all clinical improvement. (bmj.com)
  • Disease Activity Score-28-defined remission = 25.3% vs 45.3% at Years 1 and 5, respectively). (jrheum.org)
  • Introduction In the past 20 years, the increasing burden of heart disease in an ageing population has resulted in cardiac surgery (CS) being offered to more frail and older patients with multiple comorbidities. (bmj.com)
  • Patients with early-onset AN are at particularly great risk of suffering from the long-term physical and psychological consequences of persistent gonadal dysfunction. (biomedcentral.com)
  • Patients were treated actively with conventional doses of standard disease suppressing drugs. (bmj.com)
  • Some studies reported significant associations between their opinion and how good the relationship was (8, 9, 10), while others did not find an association (11), and some studies reported a higher significant rates for the relationship perceived by the patient (8, 9). (romjpsychiat.ro)
  • The incidence of diabetes mellitus in psychiatric patients has been found to be 2 to 8 times higher than in the general population [1-3]. (who.int)
  • Over 3,200 new cases are registered in the UK each year [ 2 ] and although rare in the UK, the incidence of primary liver carcinoma is predicted to rise in the future as a consequence of the hepatitis C virus epidemic and alcohol and nonalcoholic steatohepatitis (NASH) [ 3 - 5 ]. (hindawi.com)
  • 1 It has an incidence of 2%, has an even gender distribution and occurs in all ages, with a peak incidence in the fourth and fifth decades of life, and the dominant arm is involved in 75% of patients. (bmj.com)
  • Incidence rates of adverse events (AE) and serious AE were 489.7 and 20.0/100 patient-years in Year 1 versus 374.9 and 18.9/100 patient-years in the cumulative period, respectively. (jrheum.org)
  • Thirty-seven patients (median age 61.5 years) were enrolled. (jcancer.org)
  • A total of 172 female adolescent patients with first-onset AN according to DSM-IV criteria were recruited for inclusion in a randomized, multi-center, German clinical trial. (biomedcentral.com)
  • Patients with premenarchal onset of AN are at particular risk for protracted amenorrhea despite weight rehabilitation. (biomedcentral.com)
  • Patients with adolescent-onset AN are at particular risk of suffering from long-term physical and neuropsychiatric consequences of continuous gonadal dysfunction. (biomedcentral.com)
  • One-hundred and fifty CS patients will be randomised to receive either a leucine-rich protein supplement or a placebo with no supplemented protein. (bmj.com)
  • Patients were randomized to abatacept 10 or 2 mg/kg or placebo, plus MTX. (jrheum.org)
  • However, it is recommended to perform therapeutic nerve blocks even in patients with suspected endopelvic pudendal nerve pathology before the referral to surgery. (researchsquare.com)
  • One of these studies evaluated therapeutic alliance in these patients, while undergoing a group therapy intervention (1). (romjpsychiat.ro)
  • High variations in therapy alliance levels appear in patients with worsening negative symptomatology, after therapeutic intervention. (romjpsychiat.ro)
  • Papers were excluded if they did not clearly report on clinically-verified gender dysphoria, if they were focused on adult populations, if they did not include original data (epidemiological, clinical, or survey) on adolescents (aged at least 12 and under 18 years), or if they were not peer-reviewed journal publications. (plos.org)
  • Two reviewers independently identified, extracted the data, and evaluated the papers according to Newcastle-Ottawa criteria. (bvsalud.org)
  • Using national survey data to compare changes in disparities in past-year dental use and untreated dental caries by income between adults and youth sheds light on the potential impact of expanding the dental safety net. (cdc.gov)
  • To avoid circularity, the task force has proposed to use the start of DMARD therapy as a surrogate endpoint in the data-driven process of developing new candidate criteria. (biomedcentral.com)
  • Healthcare practitioners' views regarding the recognition and modulation of contextual factors (CFs) during routine clinical practice is important and has the potential to improve the quality and effectiveness of patient care [ 1 , 2 ]. (biomedcentral.com)
  • Metformin is a widely used hypoglycemic agent for patients with T2DM and has been shown to play a potentially beneficial role in improving the survival of patients with HCC. (bvsalud.org)
  • Based on discussions with the regulatory authorities, the primary endpoint of the trial was the change in daily 'ON' time, as assessed by the patient completed daily diary cards (18 hours/day). (news-medical.net)
  • In phase 2, we will conduct a single-arm feasibility pilot of the engagement system among patients with prediabetes and their primary care providers. (researchprotocols.org)
  • Consecutive patients with shoulder pain were recruited prospectively from primary health care clinics. (biomedcentral.com)
  • Disorders of the acromioclavicular joint (ACJ) are a common cause of shoulder pain in primary care, affecting patients of all ages and levels of activity[ 1 ]. (biomedcentral.com)
  • Six clinics in a primary care network in New York City, 3 of which are federally qualified health centers, have established an evidence-based diabetes management system grounded in CCM principles in the context of developing a patient-centered medical home in each clinic (14). (cdc.gov)
  • Criteria for classifying normal occlusions and malocclusions were: terminal relationship primary second molars, canine relationship, transverse relationship, goodwill and presence / absence of crowding. (bvsalud.org)
  • Chemotherapy-naïve patients with pathologically-proven locally advanced, recurrent, or metastatic pancreatic adenocarcinoma were assessed for eligibility. (jcancer.org)
  • Following the approval of gemcitabine by the US Food and Drug Administration in 1997 [ 4 ], gemcitabine-based chemotherapy was considered the standard of care for patients with advanced PDAC for a decade. (jcancer.org)
  • Patients with preoperatively staged T3 or T4 N1 disease should be considered for clinical trials of neoadjuvant chemotherapy. (medscape.com)
  • Following R0 resection of T2-4 disease in N1 gallbladder cancer, patients should be considered for adjuvant systemic chemotherapy and/or chemoradiotherapy. (medscape.com)
  • NCCN guidelines recommend consideration of a course of neoadjuvant chemotherapy for patients with jaundice. (medscape.com)
  • The Cancer of the Liver Italian Program (CLIP) classification [ 14 ] and the Chinese University Prognostic index (CUPI score) [ 15 ] tend to classify patients who have more advanced disease and are not descriptive enough to be able to distinguish those patients with lower volume of disease who may benefit the most from surgical intervention. (hindawi.com)
  • Detection of painful ACJ conditions is also of prognostic significance having been identified as one of the strongest factors associated with reduced patient satisfaction[ 8 ] and with reduced functional ability following rotator cuff repair surgery[ 9 ]. (biomedcentral.com)
  • The enhanced diabetes management system is designed to facilitate the management of patients identified through the screening program as having diabetes or prediabetes. (cdc.gov)
  • For a 6% non-inferiority margin and considering a 5% withdrawal rate, 284 patients will be included. (bmj.com)
  • In recent years, an increasing number of patients are receiving biologic or immune-modulating agents with immunosuppressive potential ( 4 , 5 ). (cdc.gov)
  • In recent years, a very close relationship between the gut-lung axis microecology and malignant tumors have been found in some studies. (biomedcentral.com)
  • Effective approaches must appeal to both patients and clinicians. (ahrq.gov)
  • 16 In addition, by using the structured clinical interview for the DSM-III-R ( Diagnostic and Statistical Manual of Mental Disorders , third edition, revised) 17 we excluded patients who also had a current psychiatric disorder or symptomatic insomnia because of the separate effects of these conditions on fatigue. (bmj.com)
  • Treat patients with risk factors for cerebrovascular disease. (medscape.com)
  • In some cases, the institution sponsoring the trial compensates the physician or group enrolling the patients. (gacancer.com)
  • For Kundert, it makes sense to use virtual tools when it best suits the patient rather than trying to implement a 100% virtual trial. (acrpnet.org)
  • A major limitation of the extant reviews is the lack of rigorous investigation of clinical characteristics that would maximize the benefit harms ratio in favor of surgical patients. (biomedcentral.com)
  • We will focus on the identification of surgical models and patient characteristics that have shown benefit and adverse effects from pregabalin. (biomedcentral.com)