Counteract protein stability. Medical search. Frequent questions

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Anatomy12

Cell Line HEK293 Cells Cell Line, Tumor HeLa Cells COS Cells Cell Nucleus Cells, Cultured NIH 3T3 Cells Cytoplasm Fibroblasts HCT116 Cells Tumor Cells, Cultured

Organisms8

Escherichia coli Saccharomyces cerevisiae Bacteriophage T4 Cercopithecus aethiops Mice, Knockout Bacillus Cricetinae Thermotoga maritima

Diseases1

Genomic Instability

Chemicals and Drugs108

Proteins Proteasome Endopeptidase Complex Ubiquitin Guanidine Ubiquitin-Protein Ligases Urea RNA, Messenger Muramidase Solvents Recombinant Proteins Mutant Proteins Nuclear Proteins DNA-Binding Proteins Transcription Factors Recombinant Fusion Proteins Leupeptins Bacterial Proteins Tumor Suppressor Protein p53 Proto-Oncogene Proteins c-mdm2 Amino Acids Salts Proteasome Inhibitors Lysine Serine F-Box Proteins Multiprotein Complexes RNA, Small Interfering Tumor Suppressor Proteins Solutions Ribonucleases Carrier Proteins Glycogen Synthase Kinase 3 Disulfides Lactalbumin Cysteine Complex Mixtures Cell Cycle Proteins Protein-Serine-Threonine Kinases Peptidylprolyl Isomerase Water Cullin Proteins Repressor Proteins Proto-Oncogene Proteins c-myc Membrane Proteins SUMO-1 Protein DNA Primers Hypoxia-Inducible Factor 1, alpha Subunit Apoproteins DNA Proline Ubiquitin-Specific Proteases Ubiquitins Alanine HSP90 Heat-Shock Proteins Molecular Chaperones Peptides Micrococcal Nuclease Trans-Activators SKP Cullin F-Box Protein Ligases Protein Isoforms Ribonuclease T1 Tryptophan Saccharomyces cerevisiae Proteins RNA-Binding Proteins Multienzyme Complexes Histidine Protein Subunits Plant Proteins Cysteine Endopeptidases Thermolysin Methylamines Small Ubiquitin-Related Modifier Proteins beta-Transducin Repeat-Containing Proteins Peptide Hydrolases Escherichia coli Proteins Ligands Anilino Naphthalenesulfonates Hypoxia-Inducible Factor-Proline Dioxygenases Protein Synthesis Inhibitors Intracellular Signaling Peptides and Proteins Cycloheximide Threonine Proto-Oncogene Proteins Chymotrypsinogen Arabidopsis Proteins Cyclin-Dependent Kinase Inhibitor p21 Casein Kinase II Adaptor Proteins, Signal Transducing Sarcosine PTEN Phosphohydrolase Green Fluorescent Proteins Endopeptidases Von Hippel-Lindau Tumor Suppressor Protein Ribonuclease, Pancreatic Axin Protein Myoglobin Guanidines Azurin RNA Arginine Tacrolimus Binding Protein 1A p300-CBP Transcription Factors Tacrolimus Binding Proteins Betaine Detergents S-Phase Kinase-Associated Proteins Ubiquitin Thiolesterase Thioredoxins

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Enzyme Stability Drug Stability Protein Denaturation Models, Molecular Circular Dichroism Protein Engineering Amino Acid Substitution Mutagenesis, Site-Directed Protein Unfolding Calorimetry, Differential Scanning Models, Chemical Spectrometry, Fluorescence Crystallography, X-Ray Models, Biological Sequence Alignment Transfection Immunoprecipitation Blotting, Western Sequence Analysis, Protein Calorimetry Molecular Dynamics Simulation Two-Hybrid System Techniques Nuclear Magnetic Resonance, Biomolecular Immunoblotting Magnetic Resonance Spectroscopy Drug Storage Spectrophotometry, Ultraviolet Gene Knockdown Techniques Reverse Transcriptase Polymerase Chain Reaction Protein Interaction Mapping Electrophoresis, Polyacrylamide Gel Cloning, Molecular Precipitin Tests Directed Molecular Evolution Microscopy, Fluorescence DNA Mutational Analysis

Phenomena and Processes87

Protein Stability Enzyme Stability Protein Denaturation Thermodynamics Protein Folding RNA Stability Mutation Protein Conformation Amino Acid Sequence Ubiquitination Protein Structure, Tertiary Temperature Proteolysis Protein Structure, Secondary Protein Binding Amino Acid Substitution Protein Unfolding Hot Temperature Half-Life Kinetics Protein Processing, Post-Translational Hydrogen Bonding Base Sequence Phosphorylation Hydrogen-Ion Concentration Binding Sites Transition Temperature Mutation, Missense Static Electricity Structure-Activity Relationship Amino Acid Motifs Transcription, Genetic Hydrophobic and Hydrophilic Interactions Gene Expression Regulation Signal Transduction Transfection Sequence Homology, Amino Acid Point Mutation Protein Structure, Quaternary Sumoylation Plasmids Solubility Entropy Protein Multimerization Dimerization Time Factors Protein Transport Protein Biosynthesis Molecular Dynamics Simulation Down-Regulation Mutagenesis Cell Cycle Protein Interaction Domains and Motifs Genomic Instability Sequence Deletion Conserved Sequence Algorithms RNA Interference Phenotype Physicochemical Phenomena Molecular Structure Catalytic Domain Transcriptional Activation DNA Damage Cell Proliferation Apoptosis Promoter Regions, Genetic RNA Processing, Post-Transcriptional Acetylation Glycosylation Surface Properties Substrate Specificity Gene Expression Catalysis Fluorescence Active Transport, Cell Nucleus Osmolar Concentration Molecular Conformation Genes, Reporter Gene Expression Regulation, Enzymologic Up-Regulation Gene Expression Regulation, Neoplastic Hydrolysis Evolution, Molecular Biophysical Phenomena Gene Deletion Ultraviolet Rays

Disciplines and Occupations3

Chemistry, Physical Computational Biology Biophysics

Technology, Industry, Agriculture1

Information Science7

Molecular Sequence Data Amino Acid Sequence Base Sequence Computer Simulation Molecular Dynamics Simulation Algorithms Databases, Protein

Health Care3

Temperature Hot Temperature Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Protein Stability Enzyme Stability Drug Stability Protein Denaturation Thermodynamics Protein Folding Models, Molecular RNA Stability Mutation Proteins Protein Conformation Molecular Sequence Data Amino Acid Sequence Ubiquitination Protein Structure, Tertiary Circular Dichroism Proteasome Endopeptidase Complex Temperature Proteolysis Protein Structure, Secondary Protein Binding Ubiquitin Guanidine Protein Engineering Amino Acid Substitution Mutagenesis, Site-Directed Protein Unfolding Cell Line Ubiquitin-Protein Ligases Calorimetry, Differential Scanning Hot Temperature Half-Life Kinetics Protein Processing, Post-Translational Urea HEK293 Cells Hydrogen Bonding RNA, Messenger Muramidase Solvents Base Sequence Phosphorylation Hydrogen-Ion Concentration Binding Sites Recombinant Proteins Escherichia coli Transition Temperature Mutation, Missense Models, Chemical Static Electricity Structure-Activity Relationship Cell Line, Tumor Mutant Proteins Amino Acid Motifs Nuclear Proteins Transcription, Genetic DNA-Binding Proteins Hydrophobic and Hydrophilic Interactions Transcription Factors Recombinant Fusion Proteins Leupeptins Spectrometry, Fluorescence Crystallography, X-Ray Gene Expression Regulation Bacterial Proteins Signal Transduction Computer Simulation Tumor Suppressor Protein p53 Models, Biological Proto-Oncogene Proteins c-mdm2 HeLa Cells COS Cells Sequence Alignment Transfection Sequence Homology, Amino Acid Amino Acids Salts Point Mutation Proteasome Inhibitors Lysine Protein Structure, Quaternary Sumoylation Serine Plasmids Solubility F-Box Proteins Immunoprecipitation Multiprotein Complexes RNA, Small Interfering Entropy Protein Multimerization Tumor Suppressor Proteins Solutions Dimerization Time Factors Blotting, Western Ribonucleases Sequence Analysis, Protein Carrier Proteins Calorimetry

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