• AVP resistance (AVP-R) (nephrogenic diabetes insipidus) arises from defective or absent receptor sites at the cortical collecting duct segment of the nephron (X-linked, vasopressin V2 receptor deficiency, locus Xq28) or defective or absent aquaporin, the protein that transports water at the collecting duct (autosomal recessive, locus 12q13). (medscape.com)
  • Amiloride exerts its potassium-sparing effect through the inhibition of sodium reabsorption at the DCT, the cortical collecting tubule, and the collecting duct. (medscape.com)
  • Triamterene interferes with potassium/sodium exchange (active transport) in the distal tubule, cortical collecting tubule, and collecting duct by inhibiting sodium/potassium adenosine triphosphatase (ATPase). (medscape.com)
  • Decreases sodium reabsorption in the distal convoluted tubule (interaction with NCC) [ 5 ] and cortical collecting duct of the nephron via guanosine 3',5'-cyclic monophosphate (cGMP) dependent phosphorylation of ENaC. (encyclopedia.pub)
  • Aquaporin-2 is involved in the transportation of water in the renal tubules. (medscape.com)
  • Since most ingested K is excreted through the kidneys, decreased renal function is a major factor in increased serum levels, and target values for its intake according to the degree of renal dysfunction have been established. (mdpi.com)
  • The patient was hospitalized thirteen years earlier for similar issues and was diagnosed with hypokalemic paralysis due to distal renal tubular acidosis with primary Sjögren's syndrome. (bvsalud.org)
  • Laboratory tests conducted during the second admission indicated distal renal tubular acidosis. (bvsalud.org)
  • CONCLUSIONS: This case study demonstrates that vacuolar-type H+-ATPases are associated with distal renal tubular acidosis, and distal renal tubular acidosis precedes interstitial nephritis in patients with primary Sjögren's syndrome. (bvsalud.org)
  • La acidosis tubular renal distal (ATRd) primaria es una tubulopatía poco frecuente caracterizada por la presencia de acidosis metabólica hiperclorémica. (bvsalud.org)
  • Spironolactone is a potassium-sparing diuretic that acts on the distal convoluted tubule of the kidney as an aldosterone antagonist. (medscape.com)
  • CONCLUSIONS: HRTD (most commonly distal RTA and Bartter syndrome) could be relatively common among Egyptian children, and the diagnosis seems challenging and often delayed. (bvsalud.org)
  • Among 7 dogs with histologically confirmed RCs, 4 had concurrent ICLs in ipsilateral/contralateral kidney, compared with 2/6 dogs with histologically confirmed neoplasia. (biomedcentral.com)
  • Presence of concurrent ICLs in ipsilateral/contralateral kidney does not appear reliable in differentiating benign from malignant ICLs. (biomedcentral.com)
  • Adv Chronic Kidney Dis 13: 118‐123, 2006. (comprehensivephysiology.com)
  • The CRS classification system includes a vast array of acute or chronic conditions in these two important organs, where the primary failing organ can be either the heart or the kidneys. (biomedcentral.com)
  • Last, only one case (with cystinosis) developed end-stage kidney disease. (bvsalud.org)
  • Spironolactone is a potassium-sparing diuretic that acts on the distal convoluted tubule of the kidney as an aldosterone antagonist. (medscape.com)
  • The prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Result from the Boston Kidney Biopsy Cohort Study. (istanbul.edu.tr)
  • Diuretic agents promote excretion of water and electrolytes by the kidneys. (medscape.com)
  • Acute kidney injury (AKI) is a clinical syndrome manifested by a rapid or abrupt decline in kidney function and subsequent dysregulation of the body electrolytes and volume, and abnormal retention of nitrogenous waste. (medscape.com)
  • Kidney Int. 2022 May 26:S0085-2538(22)00375-1. (charite.de)
  • Kidney Int. 2022 Jun 16:S0085-2538(22)00454-9. (charite.de)
  • In such cases there is consider- able danger of producing fatal ischemic damage to such vital structures as the liver, kidneys, and gastro-intestinal tract, as a consequence of temporary arrest of blood flow to these organs during the period re- quired to excise the aneurysm and replace it with an aortic homograft. (nih.gov)
  • Clinical associations of total kidney volume: the Fra-mingham Heart Study. (istanbul.edu.tr)
  • Apolipoprotein A-IV concentrations and clinical outcomes in a large chronic kidney disease cohort: Results from the GCKD study. (charite.de)
  • Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. (charite.de)
  • Nephron hypertrophy and glomerulosclerosis and their association with kidney function and risk factors among living donors. (istanbul.edu.tr)
  • Glomerular number and size in relation to age, kidney weight and body surface in normal man. (istanbul.edu.tr)