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  • vascular
  • ABSORB III - A Clinical Evaluation of Absorb™ BVS, the Everolimus Eluting Bioresorbable Vascular Scaffold in the Treatment of Subjects with de novo Native Coronary Artery Lesions Absorb™ is an investigational bioabsorbable vascular scaffold manufactured by Abbott. (centerwatch.com)
  • In vascular diseases, endothelial dysfunction is a systemic pathological state of the endothelium (the inner lining of blood vessels). (wikipedia.org)
  • Causes
  • A build-up of plaque causes the wall to "bulge" into the artery where blood normally flows, partly or completely restricting blood flow. (bidmc.org)
  • A description of the most common type of heart disease, its symptoms, causes, diagnosis and treatment. (dmoztools.net)
  • It can also result from increased oxidative stress (one of the causes of oxidative stress being platelets disrupting the carotid artery), hypertension, or obesity. (wikipedia.org)
  • However, if enlargement of fat cells and fat tissue causes them to become "sick," then important fat tissue functions are disrupted, and deranged responses contribute to metabolic disease. (wikipedia.org)
  • Sudden cardiac arrest can result from cardiac and non-cardiac causes including the following: Coronary artery disease (CAD), also known as ischemic heart disease, is responsible for 62 to 70 percent of all SCDs. (wikipedia.org)
  • acute coronary
  • The purpose of this study is to evaluate the cardiovascular outcomes of alogliptin compared with placebo, in addition to standard of care, in patients with type II diabetes mellitus and acute coronary syndrome. (centerwatch.com)
  • Angina
  • Chest pain that occurs regularly with activity, after eating, or at other predictable times is termed stable angina and is associated with narrowings of the arteries of the heart . (wikipedia.org)
  • These hardened and narrow arteries may lead to symptoms such as angina, a pain in the chest which may be brought about by physical activity, emotional upset or even just eating a meal. (news-medical.net)
  • If you have a stable pattern of angina, other tests may be done to determine the severity of your disease. (bidmc.org)
  • Jenner contributed papers on angina pectoris, ophthalmia, and cardiac valvular disease and commented on cowpox. (wikipedia.org)
  • healthy
  • Healthy habits can slow or even stop the disease and improve the quality and length of your life. (webmd.com)
  • Healthy coronary arteries are clean, smooth, and slick. (encyclopedia.com)
  • Healthy coronary arteries have smooth walls through which blood can easily flow through. (healthline.com)
  • Clinical studies indicate that moderate coffee consumption is benign or mildly beneficial in healthy adults, with continuing research on whether long-term consumption lowers the risk of some diseases, although there is generally poor quality of such studies. (wikipedia.org)
  • cardiac
  • In the human heart, adenosine functions as an autacoid in the regulation of various cardiac functions such as heart rate, contractility, and coronary flow. (wikipedia.org)
  • The most common cause of cardiac arrest is coronary artery disease. (wikipedia.org)
  • Cases have shown that the most common finding at postmortem examination of sudden cardiac death (SCD) is chronic high-grade stenosis of at least one segment of a major coronary artery, the arteries that supply the heart muscle with its blood supply. (wikipedia.org)
  • In an experimental setting if the left anterior descending coronary artery of the animal is ligated the downstream cardiac cellular mass is infarcted and will be injured and then die. (wikipedia.org)
  • walls
  • The artery walls are flexible and can expand to let more blood through when the heart needs to work harder. (encyclopedia.com)
  • The disease process in arteries is thought to begin with an injury to the linings and walls of the arteries. (encyclopedia.com)
  • As fat builds up over time - influenced by CAD risk factors - it can damage artery walls. (bidmc.org)
  • Your body's cells release chemicals in attempt to heal the damage, which make the artery walls sticky. (bidmc.org)
  • In turn, proteins, calcium deposits, cholesterol and other substances traveling through your blood vessels begin to stick to the artery walls, combining with fat to form plaque. (bidmc.org)
  • hypertension
  • Metabolic Syndrome (hypertension, diabetes mellitus, obesity, cerebrovascular-cardiovascular disease) In Community Survey was performed in central Bangkok. (centerwatch.com)
  • cardiovascular diseases
  • It is within the group of cardiovascular diseases of which it is the most common type. (wikipedia.org)
  • FLAP is necessary in synthesis of leukotriene, which are lipid mediators of inflammation that is involved in respiratory and cardiovascular diseases. (wikipedia.org)
  • The structure of FLAP provides a tool for the development of novel therapies for respiratory and cardiovascular diseases and for the design of focused experiments to probe the cell biology of FLAP and its role in leukotriene biosynthesis. (wikipedia.org)
  • Prevention
  • The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death in patients with coronary or peripheral artery disease. (centerwatch.com)
  • Treatment
  • Our expert cardiologists offer care and treatment, as well as a full range of procedures, for coronary artery disease. (bidmc.org)
  • This is a non-randomized, multi-center, prospective, single arm, controlled clinical study to collect information about the safety and effectiveness of the COBRA PzFTM Coronary Stent System in the treatment of de novo stenotic lesions in native coronary arteries. (centerwatch.com)
  • Monitoring CA-125 blood serum levels is also useful for determining how ovarian cancer is responding to treatment (with the duration of disease-free survival correlating with the rate of fall of CA-125) and for predicting a patient's prognosis after treatment. (wikipedia.org)
  • proteins
  • Other substances traveling through your arteries, such as proteins and cellular waste products, can stick to the plaque as well. (healthline.com)
  • blood flow
  • When a coronary artery suddenly becomes blocked and blood flow to an area of heart muscle stops, it is called a heart attack. (emoryhealthcare.org)
  • A common heart disease characterized by reduced or absent blood flow in one or more of the arteries that encircle and supply the heart. (uniprot.org)
  • Depending on how much blood is flowing through an artery at a particular point, the artery must be able to dilate or constrict to allow sufficient blood flow. (wikipedia.org)
  • If an artery is unable to dilate to the necessary amount to allow sufficient blood flow to the heart because of some issue to this flow-mediated dilation, it can be very problematic. (wikipedia.org)
  • severity
  • Some studies have described Frank's sign as a marker of cardiovascular disease but not linked to the severity of the condition. (wikipedia.org)
  • stents
  • Current implementations for Cardiology uses are sometimes limited by lengthy protocols, claustrophobia and contraindications based on some complex metallic implants (pacemakers, defibrillators, insulin pumps), while artificial valves and coronary stents are generally not problematic. (wikipedia.org)
  • Unlike angioplasty and stents, which push plaque into the vessel wall, atherectomy cuts plaque from the wall of the artery. (wikipedia.org)
  • graft
  • This phase II trial studies how well tacrolimus and mycophenolate mofetil works in preventing graft-versus-host disease in patients who have undergone total-body irradiation (TBI) with or without fludarabine phosphate followed by donor peripheral blood stem cell transplant for hematologic cancer. (clinicaltrials.gov)
  • I. To estimate the incidence of grade III/IV graft-versus-host disease (GVHD) after conditioning with 200 centigray (cGy) TBI alone or Fludarabine (fludarabine phosphate)/200 cGy TBI followed by tacrolimus (Tac)/mycophenolate mofetil (MMF) immunosuppression in patients with hematologic malignancies. (clinicaltrials.gov)
  • describes
  • Atrioventricular conduction disease (AV block) describes impairment of the electrical continuity between the atria and ventricles. (wikipedia.org)
  • Drug
  • Because this drug is thought to expand the arteries, it helps to increase the blood flow as well as increase the flow of oxygen throughout the body. (wikipedia.org)
  • human
  • D. Li, B. Yang, and J. L. Mehta, "Tumor necrosis factor- α enhances hypoxia-reoxygenation-mediated apoptosis in cultured human coronary artery endothelial cells: critical role of protein kinase C," Cardiovascular Research , vol. 42, no. 3, pp. 805-813, 1999. (hindawi.com)
  • near
  • The AV node lies at the lower back section of the interatrial septum near the opening of the coronary sinus, which conducts the normal electrical impulse from the atria to the ventricles. (wikipedia.org)
  • The most common access point is near the groin through the common femoral artery (CFA). (wikipedia.org)