AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceNamed GroupsHealth Care
C-Reactive ProteinBlood SedimentationCoronary VesselsCoronary AngiographyBiological MarkersCoronary Artery DiseaseCoronary CirculationArthritis, RheumatoidAcute-Phase ReactionAngioplasty, Balloon, CoronarySerum Amyloid A ProteinCoronary DiseaseCoronary StenosisTuberculosis, MiliarySpondylitis, AnkylosingProspective StudiesCoronary Artery BypassAntirheumatic AgentsNephelometry and TurbidimetryLeukocyte CountGold Sodium ThiomalatePolyarteritis NodosaMendelian Randomization AnalysisAcute DiseaseSeverity of Illness IndexBacterial InfectionsRheumatoid FactorOrosomucoidPolymyalgia RheumaticaArthritis, PsoriaticStatistics, NonparametricRisk FactorsComplement C4Meningitis, ViralCoronary VasospasmTreatment OutcomeSynovitisCalcitoninLatex Fixation TestsFeverAngina, UnstableTime FactorsFollow-Up StudiesCoronary AneurysmCrohn DiseasePredictive Value of TestsCoronary ThrombosisInfant, Premature, DiseasesSynovial FluidOsteoarthritisCase-Control StudiesPrognosisAcute-Phase ProteinsMyocardial InfarctionCoronary RestenosisArthritisSepsisInterleukin-6Coronary OcclusionInfant, NewbornDouble-Blind MethodCardiovascular DiseasesCross-Sectional StudiesChi-Square DistributionEnzyme-Linked Immunosorbent AssayPercutaneous Coronary InterventionPancreatitisInflammationPrednisoloneFalse Positive ReactionsAnalysis of VarianceInflammation MediatorsSensitivity and SpecificityROC CurveAnti-Inflammatory AgentsCoronary Care UnitsLipidsCohort StudiesTumor Necrosis Factor-alphaImmunoglobulin GAntibodies, MonoclonalDrug Therapy, CombinationBody Mass IndexGlucocorticoidsAutoantibodiesStentsPilot ProjectsMyocardial IschemiaElectrocardiographyTroponin TUltrasonography, InterventionalCalcinosisDogsCoronary Artery Bypass, Off-PumpRetrospective StudiesMyocardial RevascularizationVasodilator AgentsCardiac CatheterizationHemodynamicsPlatelet Aggregation Inhibitors
Computed tomographyPercutaneous coronary intAcute coronaryDiseaseMyocardialAtherosclerosisHigh-sensitivityRight coronaArteriesSerumStenosisPatientsHeartCholesterolCardiacBiomarkersAbstractCardiovascular riskPredictorsLipidsClinicalInflammatoryUnstable anginaUnderwentMortalityCalcificationLeft coronaStatinAngiographicRisk FactorsLevelsThrombosisCalcium
Computed tomography1
  • This study aimed to examine the association between hsCRP and coronary computed tomography angiography (CCTA)-detected coronary atherosclerosis in a population-based cohort. (lu.se)
Percutaneous coronary int10
Acute coronary2
  • Cardiac markers are used for the diagnosis and risk stratification of patients with chest pain and suspected acute coronary syndrome (ACS) and for management and prognosis in patients with acute heart failure, pulmonary embolism, and other disease states. (medscape.com)
  • Three separate papers published online in Neurology on March 30 describe eight cases of acute acalculous cholecystitis (AAC), two cases of hemophagocytic lymphohistiocytosis (HLH), and one occurrence of acute coronary syndrome (ACS), all linked to the drug. (medscape.com)
Disease80
  • CRP may become a novel coagulation index in coronary artery atherosclerotic disease. (researchsquare.com)
  • C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC) None. (ox.ac.uk)
  • OBJECTIVE: To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. (ox.ac.uk)
  • PARTICIPANTS: 194 418 participants, including 46 557 patients with prevalent or incident coronary heart disease. (ox.ac.uk)
  • MAIN OUTCOME MEASURES: Risk ratios for coronary heart disease associated with genetically raised C reactive protein versus risk ratios with equivalent differences in C reactive protein concentration itself, adjusted for conventional risk factors and variability in risk factor levels within individuals. (ox.ac.uk)
  • In a combined analysis, the risk ratio for coronary heart disease was 1.00 (0.90 to 1.13) per 1 SD higher genetically raised natural log (ln) concentration of C reactive protein. (ox.ac.uk)
  • The genetic findings were discordant with the risk ratio observed for coronary heart disease of 1.33 (1.23 to 1.43) per 1 SD higher circulating ln concentration of C reactive protein in prospective studies (P=0.001 for difference). (ox.ac.uk)
  • CONCLUSION: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease. (ox.ac.uk)
  • To assess associations between baseline values of four different circulating markers of inflammation and future risk of coronary heart disease, potential triggers of systemic inflammation (such as persistent infection), and other markers of inflammation. (bmj.com)
  • 506 men who died from coronary heart disease or had a non-fatal myocardial infarction and 1025 men who remained free of such disease until 1996 selected from 5661 men aged 40-59 years who provided blood samples in 1978-1980. (bmj.com)
  • Information on fatal and non-fatal coronary heart disease was obtained from medical records and death certificates. (bmj.com)
  • Compared with men in the bottom third of baseline measurements of C reactive protein, men in the top third had an odds ratio for coronary heart disease of 2.13 (95% confidence interval 1.38 to 3.28) after age, town, smoking, vascular risk factors, and indicators of socioeconomic status were adjusted for. (bmj.com)
  • In the context of results from other relevant studies these findings suggest that some inflammatory processes, unrelated to the chronic infections studied here, are likely to be involved in coronary heart disease. (bmj.com)
  • Several reports have suggested that plasma C reactive protein and other possible markers of low grade inflammation can predict increased risks of coronary heart disease, but it is not known whether the associations are causal. (bmj.com)
  • 2 6 A variety of mechanisms by which C reactive protein might directly promote vascular disease have been proposed, 7 but none is proved. (bmj.com)
  • These markers of inflammation might, however, be indicators of chronic infective processes possibly correlated with risk of coronary heart disease, such as infection by Chlamydia pneumoniae or chronic gastric infection with Helicobacter pylori . (bmj.com)
  • Inflammation in patients with coronary artery disease (CAD) has been linked to adverse clinical outcomes. (bvsalud.org)
  • Underlying coronary heart disease, chronic heart failure. (cdc.gov)
  • In this study, we aimed to investigate the possible association of isolated CAE with SUA and CRP levels.Patients and Methods: In this study, 4.600 patients undergoing coronary angiography in our hospital due to a known or suspected ischemic heart disease between January 2011 and August 2012 were retrospectively evaluated. (kosuyoluheartjournal.com)
  • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. (ox.ac.uk)
  • INTERPRETATION: CRP concentration has continuous associations with the risk of coronary heart disease, ischaemic stroke, vascular mortality, and death from several cancers and lung disease that are each of broadly similar size. (ox.ac.uk)
  • 194418 participants, including 46557 patients with prevalent or incident coronary heart disease. (ox.ac.uk)
  • Risk ratios for coronary heart disease associated with genetically raised C reactive protein versus risk ratios with equivalent differences in C reactive protein concentration itself, adjusted for conventional risk factors and variability in risk factor levels within individuals. (ox.ac.uk)
  • Blood parameters were repeatedly measured in 57 male patients with coronary heart disease during the winter of 2000/2001. (nih.gov)
  • Epidemiological and clinical studies have found associations between depression and cardiovascular disease risk factors, and coronary artery disease patients with depression have worse prognosis. (plos.org)
  • We here investigated overlap at the genome-wide level and in individual loci between depression, coronary artery disease and cardiovascular risk factors. (plos.org)
  • We used the bivariate causal mixture model (MiXeR) to quantify genome-wide polygenic overlap and the conditional/conjunctional false discovery rate (pleioFDR) method to identify shared loci, based on genome-wide association study summary statistics on depression (n = 450,619), coronary artery disease (n = 502,713) and nine cardiovascular risk factors (n = 204,402-776,078). (plos.org)
  • ConjFDR identified 79 unique loci associated with depression and coronary artery disease or cardiovascular risk factors. (plos.org)
  • Loci associated with increased risk for depression were also associated with increased risk of coronary artery disease and higher total cholesterol, low-density lipoprotein and c-reactive protein levels, while there was a mixed pattern of effect direction for the other risk factors. (plos.org)
  • Our results showed polygenic overlap between depression, coronary artery disease and several cardiovascular risk factors and suggest molecular mechanisms underlying the association between depression and increased cardiovascular disease risk. (plos.org)
  • We applied novel statistical tools for polygenic architectures to investigate if there are common genes for depression, coronary artery disease and cardiovascular risk factors (body mass index, blood pressure, lipids, type 2 diabetes and c-reactive protein). (plos.org)
  • We also identified 79 unique genomic variants associated with depression and coronary artery disease or the risk factors. (plos.org)
  • The second trial by Dr Schmermund in Circulation 2006 randomized 471 patients with no pre-existing coronary artery disease, treated for one year with either low dose (10mg/d) or high dose (80 mg/d) atorvastatin therapy. (greenmedinfo.com)
  • So our take-home is that biologic therapy, whether it's anti-IL-17 therapy or anti-TNF therapy, looks like it is beneficial for coronary disease," he said. (medscape.com)
  • Microscopic examination of the heart showed inflammatory infiltrates of the right coronary artery consistent with Kawasaki disease. (hawaii.edu)
  • C reactive protein (CRP), an important serum marker of atherosclerotic vascular disease, has recently been reported to be active inside human atherosclerotic plaques. (bmj.com)
  • The presence of CRP, complement, and oxLDL in a high proportion of plaque tissue from patients with unstable coronary artery disease implies that these surrogate markers have important proinflammatory effects inside atherosclerotic plaques. (bmj.com)
  • ABSTRACT Psychosocial factors such as depression, hostility, social isolation are associated with increased risk of coronary heart disease. (who.int)
  • Coronary heart disease. (epnet.com)
  • Available at: https://www.nhlbi.nih.gov/health-topics/coronary-heart-disease. (epnet.com)
  • Plasma cholesterol concentration, lipoprotein profile, and homocysteine levels are a few of the other markers currently incorporated into the toolbox for assessment of the risk of coronary artery disease. (ift.org)
  • OBJECTIVE -People with diabetes have an increased risk of coronary artery disease (CAD). (diabetesjournals.org)
  • Thus, through its effects on these and other variables, insulin resistance could be the underlying cause of much of coronary artery disease (CAD) ( 1 , 2 ). (diabetesjournals.org)
  • Further research is needed to determine whether or not higher levels of sICAM-1 may identify a subgroup of depressed patients at particularly high risk for cardiac events among patients with established coronary artery disease or among those without previous coronary artery disease. (ucla.edu)
  • His research interests include personalized medicine, pharmacogenetics, thrombosis, and therapies for coronary artery disease. (iu.edu)
  • I am interested in the effects of genomic or epigenetic variations on coronary thrombosis phenotypes, and use of ex-vivo thrombosis assays in risk stratification of patients with coronary artery disease. (iu.edu)
  • MicroRNA sequencing in patients with coronary artery disease - considerations for use as biomarker for thrombotic risk. (iu.edu)
  • Coronary artery aneurysm in Kawasaki disease. (jefferson.edu)
  • and Gould, Sharon, "Coronary artery aneurysm in Kawasaki disease. (jefferson.edu)
  • Several scoring systems have tried to determine the severity of coronary artery disease (CAD) to investigate the connection between CAD severity and laboratory parameters. (dovepress.com)
  • Since the late 1960s, the severity of coronary stenosis was suspected to be a prognostic factor for patients with coronary artery disease (CAD), 1 - 3 and this hypothesis was proven in several clinical studies with long follow-up periods. (dovepress.com)
  • Your family history of early coronary artery disease. (healthwise.net)
  • Early coronary artery disease means you have a male family member who was diagnosed before age 55 or a female family member who was diagnosed before age 65. (healthwise.net)
  • Usefulness of carotid intima-media thickness measurement and peripheral B-mode ultrasound scan in the clinical screening of patients with coronary artery disease. (epnet.com)
  • C-reactive protein and angiographic coronary artery disease: independent and additive predictors of risk in subjects with angina. (epnet.com)
  • Purpose The Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort is aimed to gain a better understanding of cardiovascular risk factors and their relation to the diagnosis and severity of coronary artery disease, as well as to the long-term prognosis in consecutive (including revascularised) patients referred for elective coronary angiography. (bmj.com)
  • The data contain basic patient characteristics, cardiovascular risk factors, laboratory measurements, medications, detailed information on the extent and severity of coronary artery disease, revascularisation history, treatment strategy and mortality specifics. (bmj.com)
  • 1 2 Particularly for coronary artery disease (CAD), up to now research into the determinants, such as the Framingham Heart Study, has focused mainly on aetiology and prognosis, 3 and only few studies pertain to the predictors of diagnosis or severity of angiographically ascertained CAD in larger cohorts. (bmj.com)
  • It could be coronary artery disease, heart failure or heart arrhythmia. (targetwoman.com)
  • Coronary artery disease (CAD) is the most common type of heart ailment causing heart attack. (targetwoman.com)
  • Trimetazidine (TMZ) is effective at improving clinical outcomes in chronic heart failure and stable coronary artery disease patients. (hindawi.com)
  • A sedentary lifestyle and poor cardiorespiratory fitness are independent risk factors for coronary atherosclerotic heart disease [ 8 ]. (hindawi.com)
  • Coronary artery disease is a condition in which the blood supply to the heart muscle is partially or completely blocked. (msdmanuals.com)
  • Coronary artery disease was once widely thought to be a man's disease. (msdmanuals.com)
  • After menopause, coronary artery disease becomes more common among women. (msdmanuals.com)
  • Among people aged 75 and older, a higher proportion of the people who have coronary artery disease are women because women live longer. (msdmanuals.com)
  • In high-income countries, coronary artery disease is the leading cause of death in both men and women, accounting for about one third of all deaths. (msdmanuals.com)
  • Coronary artery disease affects people of all races, but the incidence is extremely high among people of African ancestry. (msdmanuals.com)
  • In 2016 she was awarded a fellowship by the ESRC under the Future Leader's scheme to investigate the biosocial mechanisms linking depression with long term conditions such as coronary heart disease, diabetes, cancer and arthritis. (surrey.ac.uk)
  • New guidelines on screening for cardiovascular risk, released in late 2013 by the American Heart Association/American College of Cardiology (AHA/ACC), recommend use of a revised calculator for estimating the 10-year risk of developing a first atherosclerotic CVD event, which is defined as nonfatal myocardial infarction, death from coronary heart disease, or stroke (fatal or nonfatal) in a person who was initially free from atherosclerotic CVD. (medscape.com)
  • In patients with acute coronary disease, CRP level predicts mortality and cardiac complications. (medscape.com)
  • Periodontitis is a chronic infection capable of inducing an inflammatory response that increases the level of proteins during the acute phase, such as C-reactive protein, and considering that these proteins are independent risk factors for cardiovascular diseases, this could explain the connection between periodontal disease and heart disease that is, periodontal diseases increase the risk of cardiovascular diseases. (bvsalud.org)
  • Intervention (n = 29) and comparison (n = 31) participants from a 172-employee organization underwent health screening of risk factors for coronary heart disease at baseline (fall 2006) and at 12 months (fall 2007). (cdc.gov)
  • We used the Framingham Risk Score to calculate risk of coronary heart disease. (cdc.gov)
  • To calculate cost-effectiveness, we used direct employer costs of the program divided by either the relative reduction in low-density lipoprotein cholesterol or the absolute change in coronary heart disease risk. (cdc.gov)
  • 10.17 per percentage-point reduction of low-density lipoprotein cholesterol and $454.23 per point reduction in coronary heart disease risk. (cdc.gov)
  • This study demonstrated the cost-effectiveness in a small organization of a worksite health promotion that improved low-density lipoproteins and coronary heart disease risk in participating employees. (cdc.gov)
  • An elevated low-density lipoprotein cholesterol (LDL-C) is associated with coronary heart disease (CHD) and frequently coexists with metabolic syndrome. (cdc.gov)
  • There are increased risk for: Atherosclerosis, Peripheral vascular disease, Coronary heart disease, Heart attack, Stroke and Type 2 diabetes. (bvsalud.org)
  • Coronary atherosclerotic disease is a leading cause of mortality and morbidity due to major cardiovascular events in the United States and abroad. (bvsalud.org)
Myocardial5
  • Individuals with coronary calcium at fluoroscopy were three times as likely to experience revascularization, new-onset angina, myocardial infarction, or sudden death. (auntminnie.com)
  • Methods: We evaluated relationships between the LDL cholesterol and CRP levels achieved after treatment with 80 mg of atorvastatin or 40 mg of pravastatin per day and the risk of recurrent myocardial infarction or death from coronary causes among 3745 patients with acute coronary syndromes. (natap.org)
  • Specifically, on an a priori basis, we hypothesized that patients with acute coronary syndromes who had lower CRP levels as a result of statin therapy would have a lower risk of recurrent myocardial infarction or death from coronary causes than those who had higher CRP levels, even after we controlled for the achieved levels of LDL cholesterol. (natap.org)
  • Myocardial FFR has been used as an index of functional severity of coronary artery stenosis. (medscape.com)
  • C-reactive protein (CRP) is a marker of inflammation that is naturally present in the plasma at levels that may rise due to inflammatory processes, associated with a greater risk of cardiovascular events such as acute myocardial infarction. (bvsalud.org)
Atherosclerosis6
  • Despite abundant knowledge about the relationship between inflammation and coronary atherosclerosis, it is still unknown whether systemic inflammation measured as high-sensitivity C-reactive protein (hsCRP) is associated with coronary atherosclerosis in a general population. (lu.se)
  • Coronary atherosclerosis was defined as presence of plaque of any degree in any of 18 coronary segments. (lu.se)
  • Compared with hsCRP below the detection limit, elevated hsCRP (≥ 2.3 mg/L) was weakly associated with any coronary atherosclerosis (OR 1.15, 95% CI 1.07-1.24), coronary diameter stenosis ≥ 50% (OR 1.27, 95% CI 1.09-1.47), ≥ 4 segments involved (OR 1.13, 95% CI 1.01-1.26 ) and severe atherosclerosis (OR 1.33, 95% CI 1.05-1.69) after adjustment for age, sex and traditional risk factors. (lu.se)
  • In conclusion, the additional value of hsCRP to traditional risk factors in detection of coronary atherosclerosis is low. (lu.se)
  • For scientists and clinicians who carry out research about the genesis of atherosclerosis, it has always been compelling to somehow quantify the grade of severity of coronary artery calcification and stenosis. (dovepress.com)
  • Imaging tests can detect subclinical coronary atherosclerosis and aid initiation of targeted preventative efforts based on patient risk. (bvsalud.org)
High-sensitivity2
Right corona4
  • Echocardiogram revealed ectasia of the right coronary artery (RCA). (jefferson.edu)
  • As basis for their quantification, they measured the remaining lumina in the right coronary artery, main left coronary artery and its anterior descending and circumflex branches. (dovepress.com)
  • The right coronary artery and the left coronary artery, which branch off the aorta just after it leaves the heart, deliver oxygen-rich blood to the heart muscle. (msdmanuals.com)
  • The right coronary artery branches into the marginal artery and the posterior interventricular artery, located on the back surface of the heart. (msdmanuals.com)
Arteries3
  • This led the present team to question whether this was due to simply reducing systemic inflammation or a more local benefit on the coronary arteries, for example, plaque modulation. (medscape.com)
  • Recently, CRP was identified within early atherosclerotic lesions in human coronary arteries obtained at necropsy. (bmj.com)
  • In another study, 1 they used a more precise system by classifying the coronary vessels as non/slightly/moderately/severely/totally obstructed depending on the grade of obstruction in percental gradations from no to total stenosis, but they concentrated on the major arteries and branches. (dovepress.com)
Serum9
  • Plasma concentrations of C reactive protein, serum amyloid A protein, and serum albumin and leucocyte count. (bmj.com)
  • Circulating concentrations of C reactive protein, serum amyloid A protein, and serum albumin and the leucocyte count can fluctuate widely during acute responses to tissue damage or infection. (bmj.com)
  • 2 3 Moreover, highly sensitive assays for C reactive protein and serum amyloid A protein are now available that can detect low grade inflammation that would previously have been unnoticed. (bmj.com)
  • Serum uric acid (SUA) and C-reactive protein (CRP) are the most widely used markers of inflammation. (kosuyoluheartjournal.com)
  • İzole Koroner Arter Ektazilerinde Serum Ürik Asit ve C-reaktif Protein Düzeylerinin Değerlendirilmesi. (kosuyoluheartjournal.com)
  • İzole Koroner Arter Ektazilerinde Serum Ürik Asit ve C-reaktif Protein Düzeylerinin Değerlendirilmesi' Koşuyolu Heart Journal, vol. 17, no. 2, 2014, pp. 105-109. (kosuyoluheartjournal.com)
  • Dr Ware's fine article in Medical Hypotheses 2009 , reveals there is no correlation between serum cholesterol and the amount of atherosclerotic plaque when reviewing either autopsy studies or coronary calcium score studies. (greenmedinfo.com)
  • Plasma levels of soluble intercellular adhesion molecule 1 (sICAM-1) and interleukin-6 (IL-6) and the serum level of C-reactive protein were measured in 481 patients 2 months after hospitalization for acute coronary syndromes. (ucla.edu)
  • At 2 and/or 6 days, we evaluated creatine kinase (CK and CK-MB), cardiac troponin I (cTnI), C-reaction protein (CRP), serum tumor necrosis factor (TNF- α ), serum creatinine (Cr), serum urea, glucose, glutamic pyruvic transaminase (ALT), and glutamic oxaloacetic transaminase (AST). (hindawi.com)
Stenosis2
  • Introduction: Isolated coronary artery ectasia (CAE) is defined as the arterial enlargement of 1.5 times or more compared to the adjacent normal arterial portion without significant coronary artery stenosis. (kosuyoluheartjournal.com)
  • FFR represents the fraction of the normal maximal coronary flow that can be achieved in an artery in which flow is restricted by a coronary stenosis. (medscape.com)
Patients13
  • To evaluate whether preoperative C-reactive protein (CRP) can be a novel marker of postoperative bleeding in patients having off-pump coronary artery bypass grafting (CABG). (researchsquare.com)
  • p<0.001).Conclusion: We found that levels of SUA and CRP were higher in the patients with CAE than in subjects with normal coronary artery, but no significant different was found compared to patients with CAD. (kosuyoluheartjournal.com)
  • Currently we are following a number of similar patients with elevated coronary calcium score treated with statin drugs by their cardiologist. (greenmedinfo.com)
  • After psoriasis treatment with an interleukin (IL)-17 inhibitor, computed coronary tomography angiography (CCTA) in patients at low cardiovascular risk revealed reductions in noncalcified plaque, reductions in the plaque's necrotic core, and increases in its fibrous cap, which makes it harder for plaques to rupture. (medscape.com)
  • Last year, the researchers reported that patients with psoriasis have a coronary plaque burden equivalent to that of a person about 10 years older with hyperlipidemia. (medscape.com)
  • To investigate the simultaneous presence of macrophages, CRP, membrane attack complex C5b-9 (MAC), and oxidised low density lipoprotein (oxLDL) in atherectomy specimens from patients with different coronary syndromes. (bmj.com)
  • The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes. (ucla.edu)
  • This study was conducted to determine whether or not depression is associated with higher levels of inflammatory markers in patients recovering from acute coronary syndromes. (ucla.edu)
  • Depressed patients not taking statins had markedly higher C-reactive protein levels than did nondepressed patients. (ucla.edu)
  • These results suggest chronic endothelial activation among depressed patients after acute coronary syndromes. (ucla.edu)
  • We prospectively addressed this issue among 3745 patients with acute coronary syndromes who were randomly assigned to receive either intensive or moderate lipid-lowering therapy with a statin. (natap.org)
  • Our data indicate that among patients with acute coronary syndromes who are treated with a statin, achieving a target level of CRP of less than 2 mg per liter is associated with a significant improvement in event-free survival, an effect present at all levels of LDL cholesterol achieved. (natap.org)
  • High CRP levels portend a worse prognosis in patients with acute coronary syndromes. (medscape.com)
Heart3
  • Jim has an elevated coronary calcium score in the 95% percentile indicating high risk for future heart attack . (greenmedinfo.com)
  • The elevated calcium score indicates higher risk for future coronary event such as chest pain, angina , heart attack etc. (greenmedinfo.com)
  • Gross evaluation of the heart showed mild chamber dilatation, mitral and aortic valvulitis, focal myocarditis, and right coronary arteritis. (hawaii.edu)
Cholesterol5
Cardiac3
  • The troponins are regulatory proteins found in skeletal and cardiac muscle. (medscape.com)
  • C-reactive protein (CRP) and other biomarkers as cardiac risk factors. (epnet.com)
  • C-reactive protein (CRP) as a cardiac risk factor. (epnet.com)
Biomarkers2
  • Among the numerous biomarkers evaluated, C-reactive protein (CRP) has been the most intensely studied. (efim.org)
  • The coronary score would offer a suitable tool for the investigation of the connection between CAD and new biomarkers. (dovepress.com)
Abstract1
  • ABSTRACT This study investigated whether breast arterial calcification (BAC) has an association with coronary artery diseases (CAD) in young premenopausal women and evaluated the association of BAC with carotid intima-media thickness and standard CAD risk factors. (who.int)
Cardiovascular risk1
  • 3 Moreover, inflammatory markers, such as C reactive protein (CRP), are strong independent predictors of future cardiovascular risk. (bmj.com)
Predictors1
  • Stepwise multiple regression analysis with backward elimination revealed diabetes status, sex, and fibrinogen Clauss as significant predictors of coronary score. (dovepress.com)
Lipids1
  • In this regard, TMZ may protect cardiomyocytes against excessive oxygen free radical (OFR) production that occurs in ischemia and inflammation and that initiates oxidation of lipids and proteins and damages DNA. (hindawi.com)
Clinical2
  • The association to high-risk noncalcified plaques, although unlikely through a causal pathway, could explain the relationship between hsCRP and clinical coronary events in numerous studies. (lu.se)
  • Increases in CRP concentration are non-specific and should be used in conjunction with traditional clinical laboratory evaluation of acute coronary syndromes. (cdc.gov)
Inflammatory3
  • Especially in chronic inflammatory diseases like psoriasis, targeting specific cytokines like IL-17 or TNF-a may have a similar effect, not only by preventing coronary plaque progression, but even by reducing the volume of existing plaques, leading to plaque regression," he said. (medscape.com)
  • This protein is produced whenever an inflammatory process is initiated in the body and under normal physiological conditions, such as everyday stress, pregnancy, and aging. (ift.org)
  • C-reactive protein (CRP) is an acute-phase protein of the pentraxin family produced in the liver in response to inflammatory signals, particularly interleukin-6, which is synergistically enhanced by IL-1β. (nature.com)
Unstable angina2
  • Unstable Angina) Acute coronary syndromes result from a sudden blockage in a coronary artery. (msdmanuals.com)
  • This suggests that although measurements of coronary flow reserve (CFR) and fractional flow reserve (FFR), both of which are discussed below, may be useful in the assessment of the severity of stenoses and in the identification of lesions responsible for effort angina, they are not likely to identify the more dangerous plaques responsible for unstable angina, AMI, and sudden ischemic death. (medscape.com)
Underwent1
  • n = 18) underwent directional coronary atherectomy for coronary lesions. (bmj.com)
Mortality1
  • Moreover, slightly elevated CRP is an independent predictor of coronary events and stroke and has been associated with cardiovascular mortality and all-cause mortality in adults. (nature.com)
Calcification1
  • statin treatment does not have a major effect on the rate of progression of coronary artery calcification. (greenmedinfo.com)
Left corona1
  • The left coronary artery (typically called the left main coronary artery) branches into the circumflex and the left anterior descending artery. (msdmanuals.com)
Statin3
  • as of the year 2010 there had been five randomized controlled studies showing that statin drug treatment does not reduce coronary calcium score. (greenmedinfo.com)
  • Worse, the statin treatment showed progression of coronary calcium score indistinguishable from the non-treated placebo group. (greenmedinfo.com)
  • Although there was no significant association between depression and IL-6, there was an interaction between depression and statin therapy for levels of C-reactive protein. (ucla.edu)
Angiographic1
  • 55 years who were referred for coronary angiography, 34 (40.5%) had abnormal angiographic findings and 6 (7.1%) showed BAC in their mammograms. (who.int)
Risk Factors1
  • Information was available on four CRP gene tagging single nucleotide polymorphisms (rs3093077, rs1205, rs1130864, rs1800947), concentration of C reactive protein, and levels of other risk factors. (ox.ac.uk)
Levels5
Thrombosis1
Calcium2
  • We've known about coronary calcium from the very beginning, so a big problem is individuals not learning from the past," he said. (auntminnie.com)
  • Results of tests such as C-reactive protein, coronary calcium scan, or ankle-brachial index. (healthwise.net)