• corneal
  • It is characterized by changes in corneal collagen structure and organization which leads to progressive stretching and thinning of the cornea . (medcraveonline.com)
  • This treatment increases the stiffness of the cornea by causing the addition of new covalent bonds between and within the corneal collagen fibrils , subsequently improving the shape and refractive properties of the cornea. (medcraveonline.com)
  • Because the whorl-like characteristic pattern of the corneal subbasal nerve plexus is in the inferocentral cornea, we evaluated whether IVCM images of the whorl-like patterns can accurately evaluate the corneal nerve fibers in diabetic neuropathy. (arvojournals.org)
  • Forty-seven patients with diabetes (DM group) and 21 healthy control subjects underwent IVCM examination to compare the characteristics of the corneal subbasal nerve plexus around the central cornea (conventional method) and the whorl-like pattern in the inferocentral cornea (study method). (arvojournals.org)
  • In vivo corneal confocal microscopy (IVCM), a novel noninvasive technique to obtain repeated images of the small nerve fibers that compose the corneal subbasal nerve plexus, 5 is now used to evaluate diabetic polyneuropathy because the cornea is the most richly innervated bodily tissue. (arvojournals.org)
  • However, it may not as specific as corneal pachymetry , because corneal topography only evaluates the degree and distribution of surface irregularities on the cornea, not the thickness of the cornea. (wikipedia.org)
  • Corneal transplant surgery may be difficult due to the peripheral thinning of the cornea, even with large and off-center grafts. (wikipedia.org)
  • astigmatism
  • The portion of the cornea that is immediately adjacent to the limbus is spared, usually a strip of about 1-2 mm. In PMD we can see high against the rule astigmatism along with horizontal bow ties. (wikipedia.org)
  • leads
  • However, in rare cases, PMD may present with sudden onset vision loss and excruciating eye pain, which occurs if the thinning of the cornea leads to perforation . (wikipedia.org)