• patients
  • Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics should undergo fasting blood glucose testing. (drugs.com)
  • According to the manufacturer, patients treated with quetiapine in 3- to 6-week placebo-controlled trials had increases in cholesterol and triglyceride of 11% and 17%, respectively, compared to slight decreases in the placebo group. (drugs.com)
  • Primary or secondary prevention: Note: Treatment initiation using either moderate- or high-intensity statin therapy is recommended in qualifying patients based on ASCVD risk assessment criteria and baseline non-HDL-C and LDL-C values. (etok.info)
  • Geriatric: Plasma concentrations of atorvastatin in healthy elderly subjects are higher than those in young adults, and clinical data suggests a greater degree of LDL-lowering at any dose for patients in the population as compared to young adults. (wikipedia.org)
  • In 1982, some small-scale clinical investigations of lovastatin, a polyketide-derived natural product isolated from Aspergillus terreus, in very high-risk patients were undertaken, in which dramatic reductions in LDL cholesterol were observed, with very few adverse effects. (wikipedia.org)
  • The clinical presentation is similar to people with congenital lipodystrophy: the only difference is that AGL patients are born with normal fat distribution and symptoms develop in childhood and adolescence years and rarely begins after 30 years of age. (wikipedia.org)
  • Importantly, patients with symptoms that last more than one hour are more likely to have permanent neurologic damage, making prompt diagnosis and treatment important to maximize recovery. (wikipedia.org)
  • stroke
  • Too much bad cholesterol can increase your chance of getting heart disease, stroke, and other problems. (medlineplus.gov)
  • LDL cholesterol is called "bad" because high levels mean a higher risk of heart attack and stroke. (livestrong.com)
  • Signs and symptoms of a stroke depend upon the part of the brain affected and how much damage occurred. (drugs.com)
  • Mitral stenosis poses a high risk of forming emboli which may travel to the brain and cause stroke. (wikipedia.org)
  • Initial symptoms, as promoted by the American Stroke Association, are FAST (stroke), representing F = Facial weakness (droop), A = Arm weakness (drift), S = Speech difficulty (slur), and T = Time to act (priority of intervention). (wikipedia.org)
  • Any one of these symptoms, whether seen alone or in combination, should be assumed to be stroke until proven otherwise. (wikipedia.org)
  • After the initial stroke, other symptoms depend on the area of the brain affected. (wikipedia.org)
  • The American Heart Association and the American Stroke Association (AHA/ASA) now define TIA as a brief episode of neurological dysfunction with a vascular cause, with clinical symptoms typically lasting less than one hour, and without evidence of infarction on imaging. (wikipedia.org)
  • TIA causes the same symptoms associated with stroke, such as paralysis, weakness, or numbness on one side of the body. (wikipedia.org)
  • In ischemic stroke, symptoms generally persist beyond 7 days. (wikipedia.org)
  • While a TIA must by definition be associated with symptoms, a stroke may be symptomatic or silent. (wikipedia.org)
  • In silent stroke, also known as silent cerebral infarct (SCI), there is permanent infarction present on imaging, but there are no immediately observable symptoms. (wikipedia.org)
  • include
  • It can include several conditions, but usually refers to a high cholesterol and triglyceride level. (news-medical.net)
  • Symptoms of embolisation in an organ vary with the organ involved but commonly include: Pain in the involved body part Temporarily decreased organ function Later symptoms are closely related to infarction of the affected tissue. (wikipedia.org)
  • Symptoms of limb infarction include coldness, decreased or no pulse beyond the site of blockage, pain, muscle spasm, numbness and tingling, pallor and muscle weakness, possibly to the grade of paralysis in the affected limb. (wikipedia.org)
  • Some of the symptoms include: Heart failure (Dilated cardiomyopathy) in over 60% of cases, usually within the first few weeks after birth, but sometimes the onset is in adolescence or adulthood. (wikipedia.org)
  • If one of the three central nervous system pathways is affected, symptoms can include numbness, reduced sensation, and hyperreflexia. (wikipedia.org)
  • Symptoms can include altered breathing, problems with balance, drooping of eyelids, and decreased sensation in the face. (wikipedia.org)
  • Side effects of nandrolone decanoate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. (wikipedia.org)
  • Other symptoms may include weight gain, feeling tired, and foamy urine. (wikipedia.org)
  • Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. (wikipedia.org)
  • Eye signs in TED In moderate active disease, the signs and symptoms are persistent and increasing and include myopathy. (wikipedia.org)
  • The most common presenting symptoms of TIA are focal neurologic deficits, which can include, but are not limited to: Amaurosis fugax (painless, temporary loss of vision) One-sided facial droop One-sided motor weakness Diplopia (double vision) Problems with balance and spatial orientation A detailed neurologic exam, including a thorough cranial nerve exam, is important to identify these findings and to differentiate them from mimickers of TIA. (wikipedia.org)
  • Chronic
  • More commonly, infants with GSD I tolerate without obvious symptoms a chronic, mild hypoglycemia, and compensated lactic acidosis between feedings. (wikipedia.org)
  • Statins
  • HMG-CoA reductase inhibitors, commonly known as statins, are one class of drugs that lower blood cholesterol levels. (medicinenet.com)
  • Controlling Cholesterol with Statins. (medicinenet.com)
  • Statins are one kind of drug that lowers cholesterol and has been proven to reduce the chance of heart disease. (medlineplus.gov)
  • Randomized controlled trials (RCTs) have found that treating with statins reduces ASCVD events. (aafp.org)
  • Based on these data, the Blood Cholesterol Expert Panel from the American College of Cardiology (ACC) and the American Heart Association (AHA) issued an updated evidence-based guideline in 2013 that addresses the use of fixed doses of cholesterol-lowering drugs (statins) to reduce the risk of ASCVD in adults 21 years and older. (aafp.org)
  • Specific statins and dosages noted in bold were evaluated in RCTs included in critical question 1, critical question 2, and the Cholesterol Treatment Trialists 2010 meta-analysis included in critical question 3 (see full guideline for details). (aafp.org)
  • Causes
  • Nystagmus (usually affects the children) one of the first symptoms to occur which causes involuntary rapid eye movement. (wikipedia.org)
  • risk
  • What puts me at a higher risk to have a cerebrovascular accident? (drugs.com)
  • Have cholesterol tests starting at age 20-or younger if you have risk factors. (doctors-hospital.net)
  • A lack of exercise can therefore increase the risk of high cholesterol. (news-medical.net)
  • It is well recognized that obese women are at increased risk of preeclampsia and that women who have never been pregnant are at higher risk of preeclampsia than women who have had children in the past. (wikipedia.org)
  • Nandrolone esters have also more recently been proposed for the treatment of androgen deficiency in men due to favorable properties including their high ratio of anabolic to androgenic effect and consequent much lower risk of prostate enlargement, prostate cancer, and scalp hair loss relative to testosterone. (wikipedia.org)
  • lovastatin
  • Mevalonate is a required building block for cholesterol biosynthesis and lovastatin interferes with its production by acting as a reversible competitive inhibitor for HMG-CoA, which binds to the HMG-CoA reductase. (wikipedia.org)
  • Compactin and lovastatin, natural products with a powerful inhibitory effect on HMG-CoA reductase, were discovered in the 1970s, and taken into clinical development as potential drugs for lowering LDL cholesterol. (wikipedia.org)
  • Lovastatin is also naturally produced by certain higher fungi, such as Pleurotus ostreatus (oyster mushroom) and closely related Pleurotus spp. (wikipedia.org)
  • Earlier
  • A possible explanation for this is that the tomatine only in the deprotonated form binds to cholesterol to form the earlier mentioned complexes. (wikipedia.org)
  • body
  • Cholesterol is a fatty, waxy substance that is present in every cell of the body and is carried in the bloodstream. (medicinenet.com)
  • Cholesterol plays a number of roles in maintaining vital body functions including hormone production and digestion. (medicinenet.com)
  • In order to assess the effectiveness of a hop extract (HE) for postmenopausal symptoms, the effects of Lifenol on ovariectomy-induced osteoporosis, hyperlipidemia, body weight increase, and hot flash were investigated in rats. (hindawi.com)
  • In the body cholesterol localizes in the cell membranes and is responsible for maintaining its structural integrity. (boloji.com)
  • The steroid hormones in the body are also derived from cholesterol which provides the basic chemical skeleton. (boloji.com)
  • Death of a part of the brain may lead to loss of certain body functions controlled by that affected part. (drugs.com)
  • When the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. (wikipedia.org)
  • one of insulin's effects is to control arterial wall tension throughout the body Acanthosis nigricans - insulin prevents lipolysis of adipose tissues. (wikipedia.org)
  • Yellow deposits of cholesterol-rich fat may be seen in various places on the body such as around the eyelids (known as xanthelasma palpebrarum), the outer margin of the iris (known as arcus senilis corneae), and in the tendons of the hands, elbows, knees and feet, particularly the Achilles tendon (known as a tendon xanthoma). (wikipedia.org)
  • Symptoms occur on the opposite side of the body from the affected hemisphere of the brain (contralateral hemiparesis or hemianesthesia). (wikipedia.org)
  • Diagnosis
  • In general, focal deficits make TIA more likely, but the absence of focal findings do not exclude the diagnosis and further evaluation may be warranted if clinical suspicion for TIA is high (see "Diagnosis" section below). (wikipedia.org)