DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceNamed GroupsHealth Care
gamma-GlutamyltransferaseHydroxylaminesGlutamate-Ammonia LigaseAcyltransferasesBiological EvolutionTime FactorsPhylogenyRisk FactorsAlcoholismAlcohol DrinkingEthanolAlcohol-Related DisordersTemperanceAlcohol DeterrentsChild of Impaired Parents
TransferaseCardiovascularPlacebo-controlledAlanine aminotransferaseGlucose controlPrevalenceTested the efficacyFavorableAdverseClinicalGeneticInterventionHumansMetabolicInflammationComplicationsMethodsDiabetesDouble-blindPatientsStudyGroupComponentDietaryHealthy controlsDataContentHealthLevelsDiseaseDamageTotalLowerCellBloodFoundReports
Transferase2
  • Liver functions were assessed using levels of gamma-glutamyl transferase (γ-GT), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) and inflammatory statuses were assessed using serum high-sensitive C-reactive peptide (hs-CRP) concentrations. (nutraingredients.com)
  • Bloodwork showed leukocytosis (13 K/mcl), alkaline phosphatase (141 U/L), total bilirubin (2.0 mg/dL), and gamma-glutamyl transferase (172 U/L). Computed Tomography (CT) revealed multiple hepatic cysts with the largest measuring 17 × 14 × 18 cm (Figure 1). (bvsalud.org)
Cardiovascular4
  • OBJECTIVE: To evaluate the association of atherosclerotic cardiovascular disease (ASCVD) risk factors with incident ASCVD events among type 2 diabetes (T2D) individuals with microvascular complications. (bvsalud.org)
  • The expanding list of nontraditional biomarkers is outweighed by the standard risk factors for predicting future cardiovascular events and adds only moderately to standard risk factors. (medscape.com)
  • The most informative biomarkers for predicting major cardiovascular events were BNP and the urinary albumin-to-creatinine ratio. (medscape.com)
  • We analyzed the US National Readmission Database (NRD) to investigate the incidence of combined LAAO + CA and compare major adverse cardiovascular events (MACEs) with matched LAAO-only and CA-only patients. (bvsalud.org)
Placebo-controlled5
  • We systematically searched three large electronic databases (up to 31 October 2020) for identifying placebo-controlled or active-controlled RCTs that used different SGLT-2 inhibitors (dapagliflozin, empagliflozin, ipragliflozin or canagliflozin) for treatment of NAFLD. (encyclopedia.pub)
  • The effect of oral choline-stabilized orthosilicic acid (ch-OSA) on markers of bone turnover and bone mineral density (BMD) was investigated in a double-blind placebo-controlled trial. (biomedcentral.com)
  • This is a randomized, parallel-group, double-blind, placebo-controlled, multi-center, phase II study in which patients, treating physicians, and the associated clinical staff as well as the sponsor clinical team are blinded. (biomedcentral.com)
  • The trial design allows the first placebo-controlled data collection on the efficacy and safety of secukinumab in patients with GCA. (biomedcentral.com)
  • This trial aimed to evaluate the anti-obesity effects and safety of Neoagaro-oligosaccharides (NAOs) in humans in a 16 week, randomized, double-blind, placebo-controlled clinical trial. (biomedcentral.com)
Alanine aminotransferase1
  • In the clinical trials, adverse reactions that occurred in at least 5 percent of patients in either ozanimod treatment group, with at least a 1 percent difference greater than the IFN β-1a group, were nasopharyngitis, headache, increased alanine aminotransferase, upper respiratory tract infection, hypertension, increased gamma-glutamyltransferase, pharyngitis and urinary tract infections. (blogspot.com)
Glucose control2
  • However, the recent ACCORD and ADVANCE trials in patients with longstanding T2DM have shown that aggressive glucose control in such patients has no clear benefits, or may even increase CVD events (3). (ddw-online.com)
  • By reducing the renal capacity to reabsorb filtered glucose, SGLT-2 inhibitors increase renal glycosuria and osmotic diuresis, thereby improving glucose control and exerting additional positive effects, such as weight loss and the lowering of blood pressure [ 11 ] . (encyclopedia.pub)
Prevalence2
  • These astonishing statistics help to illustrate the epidemic prevalence of T2DM, and the major need for effective diagnostic, intervention and disease management strategies. (ddw-online.com)
  • We tested which environmental, social, lifestyle, and health related factors of the individual contribute to the seasonal variations in mood and behavior and whether these influence the risks of the metabolic syndrome and major depressive disorder, both conditions having a high prevalence in industrialized populations. (hindawi.com)
Tested the efficacy1
  • Recent randomized controlled trials (RCTs) tested the efficacy of sodium-glucose cotransporter-2 (SGLT-2) inhibitors to specifically treat nonalcoholic fatty liver disease (NAFLD). (encyclopedia.pub)
Favorable1
  • These differences make EE more favorable for use in birth control pills than estradiol, though also result in an increased risk of blood clots and certain other rare adverse effects. (wikipedia.org)
Adverse1
  • There were no ch-OSA related adverse events observed and biochemical safety parameters remained within the normal range. (biomedcentral.com)
Clinical1
  • A meta-analysis of four small clinical trials in patients with second-degree burns shows that use of topical aloe vera reduces time to healing by about 4.4 days when compared to control groups treated with silvadene, silver sulfadiazine, or gauze containing 0.5% chlorhexidine acetate ( 110209 ). (therapeuticresearch.com)
Genetic3
  • Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry. (nature.com)
  • After attributing a regional and/or continental ancestry to each individual using genome-wide polymorphism data, we are able to capture the effect of different environmental exposures on gene expression and health-related traits, while simultaneously controlling for genetic relatedness and migration. (nature.com)
  • Twin studies suggest that substance use initiation in children and adolescents is determined primarily by environmental influences, whereas the establishment of use patterns is strongly controlled by genetic factors. (blogspot.com)
Intervention2
  • This national multicentre study is a two-arm randomised controlled trial including 460 women with GDM in a ratio of 2 (intervention):1 (usual care). (biomedcentral.com)
  • This randomised controlled trial seeks to demonstrate whether the Face-it intervention, addressing the individual, family and health care system levels, is superior to usual care in reducing diabetes risk for mothers and their families. (biomedcentral.com)
Humans1
  • Potential Risks and Side Effects of NMN - "NMN is generally considered safe, and no major side effects have been reported in humans," says Sabat. (decadethirty.com)
Metabolic1
  • Co-occurrence of the metabolic syndrome is frequent as disturbances in metabolic networks, in glucose metabolism for instance, are implicated and often form a key component in major depressive disorder [ 16 , 17 ]. (hindawi.com)
Inflammation2
  • Recent medical events resulting in tissue injury, infections, or inflammation, which may cause elevated CRP levels, should also be considered when interpreting results. (walkinlab.com)
  • Large vessel vasculitis covers the spectrum of primary vasculitis which leads to chronic granulomatous inflammation of larger arteries, e.g., temporal arteries, the aorta, or its major branches [ 1 ]. (biomedcentral.com)
Complications1
  • Prospective studies in T2DM have shown an association between the degree of hyperglycemia and the risk of micro- and macrovascular complications, including fatal CVD events. (ddw-online.com)
Methods1
  • METHODS: In this retrospective study, 64 NDR patients and 71 controls were included. (bvsalud.org)
Diabetes2
  • Insulin resistance is a major factor of prediabetes, type 2 diabetes and a range of chronic diseases. (nutraingredients.com)
  • The glucose test identifies blood sugar levels, the most direct way to not only discover diabetes, but to evaluate options for controlling the disease as well. (walkinlab.com)
Double-blind1
  • SUNBEAM is a pivotal, phase III, multicenter, randomized, double-blind, double-dummy, active-controlled trial evaluating the efficacy, safety and tolerability of two doses of oral ozanimod (0.92 mg and 0.46 mg, equivalent to 1 mg and 0.5 mg ozanimod HCl, respectively) against weekly intramuscular interferon beta-1a (Avonex®) over a 12-month treatment period. (blogspot.com)
Patients2
  • Three hundred and eighty-two stomach cancer patients and 382 healthy controls from Taixing and Changshu city of Jiangsu province were enrolled in this study. (blogspot.com)
  • All patients and control group were Caucasians of European descent. (amegroups.org)
Study2
  • In the pivotal study, the dose was reduced for grade 3 events and interrupted for grade 4 events. (medicines.org.uk)
  • The cross-section genotyping study included 155 subjects with CAD upon acute myocardial infarct and 104 control subjects. (amegroups.org)
Group2
  • Another major group of proteins in the blood, comprising the infection fighting antibodies. (walkinlab.com)
  • Group D was control, included non-obese (BMI (bvsalud.org)
Component2
  • The major component fatty acids are linoleic (44-62%), oleic (19-30%), palmitic (7-14%), linolenic (4-11%) and stearic (1.4-5.5%) 1 . (rxlist.com)
  • Agar is a major component of the cell wall of red algae. (biomedcentral.com)
Dietary1
  • It is unclear regarding associations of dietary patterns with a wide range of chronic diseases and which dietary score is more predictive of major chronic diseases. (bvsalud.org)
Healthy controls1
  • Furthermore, in 1992 Mourkarzel [ 21 ] reported that a decreased serum Si concentration in total parenterally fed infants was associated with a decreased bone mineral content compared to healthy controls. (biomedcentral.com)
Data1
  • Increasing evidence suggests that disease-related damage to grey matter is of major importance in MS. The data analyses to be presented show reductions in cortical grey matter loss and thalamic volume loss are consistent with the reductions in whole brain volume loss seen in SUNBEAM at one year for ozanimod compared with IFN β-1a. (blogspot.com)
Content1
  • If you are visiting a 3rd party website, we have no control over the content and are not responsible for and make no representation as to the accuracy or any other aspect of such resource or the privacy practices of such 3rd party. (emdserono.com)
Health1
  • Caesarean delivery in the absence of any medical indications has become a major issue of concern among the women's health professionals. (mi-rna.com)
Levels1
  • Having experienced more numerous negative life events or low levels of social support and being nonnative or a woman are predictive of affective disorder with the seasonal pattern [ 13 ]. (hindawi.com)
Disease1
  • Centers for Disease Control and Prevention. (cdc.gov)
Damage1
  • Reviewed are the phosphorylation events reporting activation of protein kinases and the key substrates critical for the DNA damage signaling (DDS). (shengsci.com)
Total1
  • Over a median follow-up of 11.7 years, a total of 1,180 cases of incident ASCVD were documented, of which 1,040 were CHD, 100 were stroke, and 40 were both CHD and stroke events. (bvsalud.org)
Lower4
  • RESULTS: EZ RR in most retinal locations was significantly lower in NDR eyes compared to controls (all P (bvsalud.org)
  • Compared with controls, NDR eyes also displayed lower RR at N2000, T2000, S1000, and I1000 of OS, at S500 and I500 of IS, and at I500 of ONL (all P (bvsalud.org)
  • Compared to controls, EZ, OS, and IS RR of the NDR eyes showed lower correlation coefficients with whole image SCP and DCP VD of parafovea and perifovea regions. (bvsalud.org)
  • The potential for abuse liability with modafinil is apparently lower than that of other controlled stimulants, though still present. (empowerpharmacy.com)
Cell1
  • One key pathological finding in giant cell arteritis (GCA) is the presence of interferon-gamma and interleukin (IL)-17 producing T helper (Th) 1 and Th17 cells in affected arteries. (biomedcentral.com)
Blood1
Found2
  • Today, EE is found in almost all combined forms of birth control pills and is nearly the exclusive estrogen used for this purpose, making it one of if not the most widely used estrogens. (wikipedia.org)
  • No significant associations were found in any of the studies, possibly due to the low numbers of SAH events. (biomedcentral.com)
Reports1
  • In France, a case was reported in Nice in 2010, after which the number of case reports has been increasing, and 9 events of autochthonous DENV transmission were identified in 2022, resulting in 65 autochthonous cases ( 3 , 4 ). (cdc.gov)