• The mean values of right ventricular fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), right ventricular ejection fraction (RVEF), right myocardial performance index (RMPI), and tricuspid annular plane systolic speed (S') were compared between patients after COVID-19 rehabilitation and healthy subjects. (hindawi.com)
  • Left Ventricular Contraction Pattern in Chronic Aortic Regurgitation and Preserved Ejection Fraction: Simultaneous Stress-Strain Analysis by Three-Dimensional Echocardiography. (uib.no)
  • The estimated left ventricular ejection fraction (LVEF) is 55%-60%, right-heart size and systolic function are normal, and no hemodynamically significant valvular disease is detected. (medscape.com)
  • MFS patients presenting with normal ejection fraction show disturbed diastolic function and higher NT-proBNP levels, which is partly explained by aortic Z-score. (scipedia.com)
  • 1) Abnormal movement of the interventricular septum early in cardiac contraction ( systole) ie in the pre-ejection phase the septum moves to the left. (blogspot.com)
  • The primary outcome was change in left ventricular pump function (ejection fraction) at six months. (escardio.org)
  • The difference was not statistically significant after adjusting for sex, baseline left ventricular ejection fraction and other factors. (escardio.org)
  • Principal investigator Dr Charlotte Stephansen, of Aarhus University Hospital, Denmark, said: "Increased left ventricular ejection fraction after CRT is associated with a better prognosis. (escardio.org)
  • 1 The abstract 'Targeting left ventricular lead implantation towards the latest electrical activation improves left ventricular ejection fraction in cardiac resynchronization therapy: a randomized controlled trial' will be presented during the session Late-breaking trials 2 on Monday 18 March at 08:30 to 10:00 WET (GMT) in the Sokolov lecture room. (escardio.org)
  • However, patients with a reduced left ventricular ejection fraction (LVEF) at baseline suffer more consequences. (acc.org)
  • The pathophysiological mechanisms underlying preserved left ventricular (LV) ejection fraction (EF) in patients with heart failure and preserved ejection fraction (HFpEF) remain incompletely understood. (frontiersin.org)
  • Among patients hospitalized for an HF incident, 47% had HF with preserved ejection fraction (HFpEF) or systolic function, which is the focus of this paper. (frontiersin.org)
  • Notably, right-sided heart failure and PH are associated with poor outcomes and in particular have been noted to occur in another type of heart failure, called heart failure with preserved ejection fraction or HFpEF, in which the heart seems to function normally but causes difficulty breathing due to a stiffening of the heart and blood vessels. (ucsf.edu)
  • Two-dimensional and Doppler echocardiography may be used to determine systolic and diastolic LV performance, the cardiac output (ejection fraction), and pulmonary artery and ventricular filling pressures. (medscape.com)
  • An alternative method uses abrupt occlusion of the aorta during isovolumic contraction to determine peak isovolumic pressure, LV volume during ejection is estimated by integrating aortic flow and synchronizing the result with LV pressure. (justia.com)
  • We evaluated whether left ventricular contractile reserve (CR), measured with strain imaging on dobutamine echocardiography (DSE), is a reliable non-invasive measure of coronary microvascular function. (nih.gov)
  • This research was aimed at exploring the changes in right ventricular function in patients after the recovery of coronavirus disease 2019 (COVID-19) under echocardiography and providing a reference for the rehabilitation and treatment of COVID-19 patients. (hindawi.com)
  • Echocardiography is one of the most commonly used examination methods to assess cardiac structure and function and plays a crucial role in the diagnosis, disease evaluation, and prognosis evaluation of cardiovascular diseases [ 11 , 12 ]. (hindawi.com)
  • 14 ] analyzed the potential role of echocardiography in the current critical period and short and long term of COVID-19 and found that echocardiography has an important role in the assessment of cardiac function in COVID-19. (hindawi.com)
  • Doppler echocardiography is ideally suited for assessment of diastolic function, being widely available, non-invasive, and less expensive than other techniques. (bmj.com)
  • Assessment of cardiovascular remodeling, diastolic function in echocardiography, and NT-proBNP was analyzed with univariate analysis and multi-parameter analysis of covariance (MANCOVA). (scipedia.com)
  • For each dog, two-dimensional (2D) echocardiography was performed to assess LA diameter and volume for each phase of the LA cycle and to assess complete, passive, and active LA function. (openveterinaryjournal.com)
  • Cardiac function was evaluated by echocardiography. (biomedcentral.com)
  • A recent study assessing cardiac function using echocardiography in a large patient population revealed an increase in LV-EF with a decrease in end-diastolic volume (EDV) and end-systolic volume (ESV) in older compared to younger individuals [ 11 ]. (biomedcentral.com)
  • Nitroxyl has also been shown to increase the sensitivity to cardiac myocytes to Ca2+, which in turn enhances the force of contraction. (wikipedia.org)
  • Incubation of electrically-paced ventricular myocytes with a membrane-permeant Ins(1,4,5) P 3 ester provoked the occurrence of spontaneous diastolic Ca 2+ transients with the same characteristics and sensitivity to 2-APB as the events stimulated by endothelin-1. (biologists.com)
  • In addition to evoking spontaneous Ca 2+ transients, stimulation of ventricular myocytes with the Ins(1,4,5) P 3 ester caused a positive inotropic effect. (biologists.com)
  • This cycle of muscle contraction and relaxation results from the precise control of calcium ions within myocytes. (medlineplus.gov)
  • It is clear that changes in the structure and function of the RYR2 channel disrupt the careful control of calcium ion flow in myocytes, which can trigger an abnormal heart rhythm in people with CPVT. (medlineplus.gov)
  • The tips of the Purkinje fibers are electrically coupled to muscle cells and the working myocytes are longitudinally connected via gap junctions, thereby initiating a coordinated, efficient contraction of the ventricles. (medscape.com)
  • Overt damage to the ventricular myocytes was indicated by absence of fura-2 loss through leaky membranes. (cdc.gov)
  • AF could lead to the loss of atrial systolic function and ventricular irregular contraction and then promote the decline of cardiac diastolic function. (hindawi.com)
  • this combination is referred to as a CRT-defibrillator (CRT-D). Current clinical guidelines recommend the use of a CRT-D in patients with moderate to severe heart failure, reduced systolic function and ventricular conduction delay. (bmj.com)
  • Ventricular ectopy associated with a structurally normal heart most commonly occurs from the right ventricular outflow tract beneath the pulmonic valve. (medscape.com)
  • Mitral annular dynamics are influenced by left ventricular load and contractility in an acute animal model. (uib.no)
  • Scholars@Duke publication: Nitric oxide improves transpulmonary vascular mechanics but does not change intrinsic right ventricular contractility in an acute respiratory distress syndrome model with permissive hypercapnia. (duke.edu)
  • With further study, RDN has been found to have significant therapeutic effects on other cardiovascular diseases, such as atrial fibrillation (AF), heart failure, and ventricular arrhythmia [ 4 - 9 ]. (hindawi.com)
  • Similar to persistent AF, paroxysmal atrial fibrillation (PAF) could also have a significant impact on cardiac diastolic function. (hindawi.com)
  • 3) Cardiovascular actions of relaxin and its therapeutic potential in the context of three pathologies: (i) relaxin-induced maternal vascular remodeling and associated functional benefits in preeclampsia, (ii) relaxin-induced left atrial remodeling and suppression of atrial fibrillation, and (iii) relaxin-induced left ventricular remodeling and associated functional benefits in the setting of diastolic dysfunction. (pitt.edu)
  • Sudden cardiac death during ventricular fibrillation results in a compromised mechanical pump function of the heart. (physiomeproject.org)
  • Disrupted patterns of electrical excitation during ventricular fibrillation results in desynchronised cardiac contractions. (physiomeproject.org)
  • Asystole, ventricular tachycardia (VT), ventricular fibrillation (VF), and pulseless electrical activity are the underlying rhythm disturbances in the pediatric age group. (thieme-connect.de)
  • Renal function and outcomes after catheter ablation of patients with atrial fibrillation: The Guangzhou atrial fibrillation ablation registry. (cdc.gov)
  • If the source is the left ventricular outflow tract, there is a right bundle-branch block pattern in V 1 . (medscape.com)
  • Comparison of ultrasound vector flow imaging and CFD simulations with PIV measurements of flow in a left ventricular outflow trackt phantom - Implications for clinical use and in silico studies. (uib.no)
  • Nitroxyl is capable of enhancing left ventricular contractility without increasing heart rate by modifying normal Ca2+ cycling through the sarcoplasmic reticulum as well as increasing the sensitivity of cardiac myofilaments to Ca2+. (wikipedia.org)
  • Vagus nerve stimulation decreases left ventricular contractility in vivo in the human and pig heart. (ox.ac.uk)
  • A premature ventricular contraction (PVC) is caused by an ectopic cardiac pacemaker located in the ventricle. (medscape.com)
  • Premature ventricular contractions (PVCs) are extra heartbeats that begin in one of the heart's two lower pumping chambers (ventricles). (nchmd.org)
  • Premature ventricular contractions are a common type of irregular heartbeat (arrhythmia). (nchmd.org)
  • Occasional premature ventricular contractions in people without heart disease usually aren't a concern and likely don't need treatment. (nchmd.org)
  • You might need treatment if the premature ventricular contractions are very frequent or bothersome, or if you have an underlying heart condition. (nchmd.org)
  • Premature ventricular contractions often cause few or no symptoms. (nchmd.org)
  • To understand the cause of premature ventricular contractions (PVCs), it might help to learn more about how the heart typically beats. (nchmd.org)
  • The cause of premature ventricular contractions isn't always clear. (nchmd.org)
  • Certain lifestyle choices and health conditions may make a person more likely to develop premature ventricular contractions (PVCs). (nchmd.org)
  • Intriguingly, therapy-resistance bigeminy with premature ventricular contractions (PVCs) continued despite all these treatments. (thieme-connect.de)
  • Hypertension and PAF can affect cardiac diastolic function. (hindawi.com)
  • The study aimed to evaluate the effect of RDN on cardiac diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • The 190 patients were divided into the decreasing HR and nondecreasing HR group, the decreasing MAP and nondecreasing MAP group, the HFPEF group, and the normal diastolic function group, respectively. (hindawi.com)
  • Before RDN, the indices about cardiac diastolic function were out of the normal range. (hindawi.com)
  • The diastolic function about the indices of NT-proBNP, E / e ′, e ′ was improved in the decreasing HR group, the decreasing mean arterial pressure (MAP) group, and the HFPEF group, correspondingly compared to the nondecreasing HR group, the non-decreasing MAP group, and the preoperative normal diastolic function group. (hindawi.com)
  • In the multivariate analysis, the MAP and HR were the only two indicators significantly associated with the improvement of diastolic function. (hindawi.com)
  • RDN could improve the diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • It was speculated that RDN improved the diastolic function mainly through decreasing HR and MAP. (hindawi.com)
  • Long-term hypertension, especially long-term uncontrolled hypertension, could directly lead to myocardial hypertrophy, myocardial wall stiffness, and compliance decline, eventually causing a decrease in diastolic function. (hindawi.com)
  • Theoretically, the RDN also has a certain effect on cardiac diastolic function in these patients. (hindawi.com)
  • In this study, we studied the changes in diastolic function in patients with refractory hypertension and PAF before and after RDN. (hindawi.com)
  • Paradoxically, the role of diastolic function assessment is more difficult to define in patients with diastolic HF. (bmj.com)
  • 4 w6 w7 Zile and colleagues demonstrated that at least one abnormal index of diastolic function was present in patients with HF and normal systolic function. (bmj.com)
  • Echocardiographic assessment of diastolic function makes the diagnosis of diastolic HF more specific, allows serial assessment of the response of diastolic dysfunction to treatment, and facilitates inclusion of more homogeneous populations into intervention trials. (bmj.com)
  • NT-proBNP, C-reactive protein (CRP) and diastolic function were assessed in 217 patients with MFS (31 ± 16 y, 110 f. and in 339 patients referred for suspected MFS in whom the diagnosis was ruled out according to the Ghent nosology (30 ± 15 y, 154 f). (scipedia.com)
  • Besides age and gender, diagnosis of MFS, diastolic function (e′ and E/e′), Z-Score of aortic diameter, and left ventricular size were identified as significant independent parameters with impact on NT-proBNP levels. (scipedia.com)
  • Assessment of diastolic function and NT-proBNP levels may therefore detect early abnormalities and guide surveillance and prevention management of patients with MFS. (scipedia.com)
  • The aim of the present study was to evaluate left ventricular diastolic function, type of cardio-vascular hypertrophy and NT-proBNP levels in out-patients with MFS and a control group with similar clinical manifestations referred for evaluation of suspected MFS in whom the diagnosis was ruled out. (scipedia.com)
  • Effect of isolated left bundle branch block on systolic and diastolic function of left ventricle), see ref 3 below. (blogspot.com)
  • We quantified alterations in myocardial function in a mathematical model of the human LV that is based on the finite element method. (frontiersin.org)
  • 1. Studies of the effect of vagus nerve stimulation on ventricular myocardial function in mammals are limited, particularly in the human. (ox.ac.uk)
  • The objective of this study was to evaluate the ability of human iPSC-CMs to improve myocardial function in a rat postinfarction heart failure model. (biomedcentral.com)
  • Human iPSC-CM grafts survived in infarcted rat hearts and restored myocardial function 4 weeks after transplantation. (biomedcentral.com)
  • This retrospective study enrolled patients who underwent CMR for assessment of myocardial function including those individuals who had normal function and no cardiac pathology. (biomedcentral.com)
  • More than 200 mutations in the RYR2 gene have been found to cause catecholaminergic polymorphic ventricular tachycardia (CPVT), a heart condition characterized by an abnormal heart rhythm (arrhythmia) during exercise or emotional stress, which can be fatal. (medlineplus.gov)
  • Researchers are uncertain how RYR2 gene mutations lead to ventricular tachycardia, the abnormally fast and irregular heart rhythm that is characteristic of CPVT. (medlineplus.gov)
  • Catecholaminergic polymorphic ventricular tachycardia: A paradigm to understand mechanisms of arrhythmias associated to impaired Ca(2+) regulation. (medlineplus.gov)
  • Gyorke S. Molecular basis of catecholaminergic polymorphic ventricular tachycardia. (medlineplus.gov)
  • The predominant effect is hypokalemia, which can result in ventricular tachycardia, hypertension and/or hypotension, muscle weakness, and paralysis. (cdc.gov)
  • Catheter ablation for monomorphic ventricular tachycardia in Brugada syndrome patients: detailed characteristics and long-term follow-up. (cdc.gov)
  • During ventricular activation, the area of slow conduction activates the blocked part of the system after the rest of the ventricle has recovered, resulting in an extra beat. (medscape.com)
  • Abnormalities in cardiac conduction can occur due to a variety of factors, including developmental and congenital defects, acquired injury or ischemia of portions of the conduction system, or less commonly due to inherited diseases that alter cardiac conduction system function. (medscape.com)
  • Next, the importance of embryonic developmental genes such as homeobox and T-box transcription factors are highlighted in conduction system development and function. (medscape.com)
  • Last, a new glycogen storage cardiomyopathy associated with ventricular preexcitation and progressive conduction system degeneration will be reviewed. (medscape.com)
  • The heart achieves the coordinated contraction of the atrial and ventricular chambers due to the precise timing of the cardiac conduction system (CCS), a specialized complex and heterogeneous network of cells that initiate and allow propagation of action potentials through the heart. (medscape.com)
  • Deformation and wall-thickening of ventricular myocardium are essential for cardiac pump function. (ox.ac.uk)
  • 8. These studies show that in the human and pig heart the left vagus nerve can profoundly decrease the inotropic state of the left ventricular myocardium independent of its bradycardic effect. (ox.ac.uk)
  • Causes of primary diastolic dysfunction include an anatomic obstruction that prevents ventricular filling (eg, pulmonary venous obstruction), a primary reduction in ventricular compliance (eg, cardiomyopathy, transplant rejection), external constraints (eg, pericardial effusion), and poor hemodynamics after the Fontan procedure (eg, elevated pulmonary vascular resistance). (medscape.com)
  • Several other mutations in the RYR2 gene have been found to cause a heart condition called arrhythmogenic right ventricular cardiomyopathy (ARVC). (medlineplus.gov)
  • MYL2 gene mutation impacts the structure and function of myosin, thereby leading to the occurrence and progression of hypertrophic and dilated cardiomyopathy as well as the following chronic heart failure. (shsmu.edu.cn)
  • Herein, we would like to report a case of a 15-year-old female patient with dilated cardiomyopathy (DCM) who was admitted to our clinic a year ago, and while her left ventricular systolic functions were improved, SCA suddenly occurred. (thieme-connect.de)
  • Hypertrophic cardiomyopathy is a congenital or acquired disorder characterized by marked ventricular hypertrophy with diastolic dysfunction (eg, due to valvular aortic stenosis, coarctation of the aorta, systemic hypertension). (msdmanuals.com)
  • Modes 2 and 9 were the most important for determining simulated left ventricular mechanics and pressure-derived phenotypes. (plos.org)
  • Understanding the transmural variations in left ventricular (LV) mechanics associated with HFpEF may offer pathophysiological insights for developing potential therapeutic targets. (frontiersin.org)
  • 4) The role of regional contraction dyssynchrony in global ventricular mechanics and energetics. (pitt.edu)
  • OBJECTIVE: To test the hypothesis that in a swine model of acute respiratory distress syndrome (ARDS) with permissive hypercapnia, inhaled nitric oxide would improve transpulmonary vascular mechanics and right ventricular workload while not changing intrinsic right ventricular contractility. (duke.edu)
  • MEASUREMENTS AND MAIN RESULTS: We evaluated the pulmonary vascular and right ventricular effects of permissive hypercapnia, with and without inhaled nitric oxide, by measuring variables of transpulmonary vascular mechanics and right ventricular function. (duke.edu)
  • The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. (uab.es)
  • Although ventricular cardiomyocytes express inositol 1,4,5-trisphosphate [Ins(1,4,5) P 3 ] receptors, it is unclear how these Ca 2+ channels contribute to the effects of Gq-coupled agonists. (biologists.com)
  • The ability of eight widely used halogenated hydrocarbons (HC) to depress calcium (Ca) ion dynamics in rat cardiomyocytes during excitation/contraction coupling was examined. (cdc.gov)
  • The heart's electrical wiring system is designed so that the impulses that cause muscle contraction spread out more or less simultaneously from the two bundle branches. (blogspot.com)
  • In LBBB the activation pattern is markedly altered so that the septum is activated from right to left with early septal activation and contraction of septal area during the isovolumic contraction phase of systole and there is delay of the impulses arriving at the lateral and posterior left ventricular wall delaying muscle contraction. (blogspot.com)
  • Severe variants in KV11.1 can predispose individuals to a fatal ventricular arrhythmia, torsades de pointes, so restoring the function of the channel has clinical importance. (phrmafoundation.org)
  • Ventricular pump function. (ucsd.edu)
  • Simulations of cardiac electrical activation and mechanical pump function in hearts with shapes described by different combinations of shape components were performed. (plos.org)
  • Late-breaking results from the ElectroCRT trial presented today at EHRA 2019 1 a European Society of Cardiology (ESC) congress, pave the way for a new standard of care to improve the heart's pump function in selected patients with heart failure. (escardio.org)
  • These impairments range from the mildest forms, which are manifest clinically only during stress, to the most advanced forms, in which cardiac pump function is unable to sustain life without external support. (medscape.com)
  • This method yields two pressure-volume points, one for the isovolumic contraction and one for the resting ejecting contraction, and by linking the two points by a line, one can estimate the slope E.sub.max. (justia.com)
  • Instead of actually occluding the Aorta to determine isovolumic pressure and volume, an approach that could never be used clinically, these investigators provided a method to estimate this pressure-volume (PV) data by mathematical curve fitting of LV data measured during isovolumic contraction and relaxation phases of a steady-state ejecting beat. (justia.com)
  • There were no differences between groups in left ventricular reverse remodelling, New York Heart Association functional class, six minute walk test, and quality of life. (escardio.org)
  • Animals injected with cell-free solution (control group) demonstrated significant left ventricular (LV) functional deterioration, whereas grafting of iPSC-CMs attenuated this remodeling process. (biomedcentral.com)
  • This retrospective cardiac magnetic resonance (CMR) study included 183 subjects with normal structural and functional ventricular values. (biomedcentral.com)
  • The aging process is associated with significant changes in left and right ventricular EF, ESV and EDV in subjects with no cardiac functional and structural abnormalities. (biomedcentral.com)
  • Elderly people with aortic stenosis used to have to undergo open-heart surgery to get a new valve but now there's transcatheter aortic valve replacement, or TAVI. (chaunceycrandall.com)
  • and pump (active contractile function), during late ventricular diastole. (openveterinaryjournal.com)
  • In end-diastole the interaction occurs between LA contraction, LV passive elastic properties, myocardial visco-elasticity, and pericardial function. (echobyweb.com)
  • Nonetheless, a recent review has highlighted the disconnect between Doppler echo measurements and true diastolic properties of the left ventricle, and has questioned the prevailing assumption that HF with preserved systolic function is always caused by diastolic dysfunction. (bmj.com)
  • 2] Systolic dysfunction is characterized by diminished ventricular contractility that results in an impaired ability to increase the stroke volume to meet systemic demands. (medscape.com)
  • Diastolic dysfunction results from decreased ventricular compliance, necessitating an increase in venous pressure to maintain adequate ventricular filling. (medscape.com)
  • The computational results simulating the effects of transmural alterations in the ventricular tissue replicate the phenotypic patterns of LV dysfunction observed in clinical practice. (frontiersin.org)
  • Heart Failure (HF) Heart failure (HF) is a syndrome of ventricular dysfunction. (msdmanuals.com)
  • Patients with acute decompensated heart failure have diminished left ventricular systolic and/or diastolic functioning. (wikipedia.org)
  • Biophysical computational models of the heart provide a quantitative framework for mapping changes in anatomy to whole heart function. (plos.org)
  • Little is known about the influence of hemodynamic changes on ventricular performance during pregnancy in patients with congenital heart disease. (nih.gov)
  • 3 However, the American College of Cardiology/American Heart Association guidelines for the evaluation and management of HF w4 support a diagnosis of exclusion-that is, clinical evidence of HF with preserved systolic function. (bmj.com)
  • Daniel's heart function had continued to deteriorate, and he needed a heart transplant. (heart.org)
  • However,at the time, It was not known what was the role of LBBB in altering cardiac function.Did it cause heart disease- this point is debated still. (blogspot.com)
  • For CRT, a pacemaker is implanted below the collarbone and three leads are attached in the heart to resynchronise the contraction by stimulation with pulses of electricity. (escardio.org)
  • ESC guidelines advise placing the left ventricular lead at the back of the heart where late activation occurs, as this improves response to CRT. (escardio.org)
  • 3 Briefly, 122 heart failure patients were randomly allocated to left ventricular lead placement at the latest electrically activated site (using electrical mapping) or the latest mechanically activated site (using imaging). (escardio.org)
  • The Danish-CRT trial, set to enrol 1,000 patients, is testing whether electrically guided positioning of the left ventricular lead reduces hospitalisation for heart failure or death compared to standard of care lead placement. (escardio.org)
  • Histo-anatomical structure of the living isolated rat heart in two contraction states assessed by diffusion tensor MRI. (ox.ac.uk)
  • Compensatory mechanisms increase blood volume, as well as the cardiac filling pressure, heart rate, and cardiac muscle mass, to maintain the pumping function of the heart and to cause a redistribution of blood flow. (medscape.com)
  • Do you know how these valves operate when it comes to breathing and helping the heart meet its function? (proprofs.com)
  • This contraction allows blood to flow into the ventricles before they contract and pump the blood out of the heart. (proprofs.com)
  • There's even good news for people with serious congestive heart failure. (chaunceycrandall.com)
  • The left ventricular assist devices, which take over the beating function of the heart, can help them. (chaunceycrandall.com)
  • In patients with chronic heart failure, especially in those with III-IV symptoms, as defined by the New York Heart Association, the prognosis is extremely poor due to irreversibly impaired left ventricular function [ 2 ]. (biomedcentral.com)
  • The treatment of heart failure remains a challenging problem as conventional treatments (drug therapy, interventional therapy, and surgery) have difficulty in restoring the function of the heart. (biomedcentral.com)
  • In the embryonic period, myosin regulatory light chain (MYL2) plays a pivotal role in the development and function of the heart. (shsmu.edu.cn)
  • The heart is constituted by three types of muscle: atrial, ventricular, and specialized excitatory and conducting fibers. (bvsalud.org)
  • From a physiological and pathophysiological point of view, the conformational states of the sodium channel during heart function constitute a significant aspect for the diagnosis and treatment of heart diseases. (bvsalud.org)
  • Meanwhile, his doctors implanted an LVAD, or left ventricular assist device, a machine that essentially does the heart's pumping. (heart.org)
  • The heart's inability to pump a sufficient amount of blood to meet the needs of the body's tissues may be a result of insufficient or defective cardiac filling and/or impaired contraction and emptying. (medscape.com)
  • PVCs are irregular contractions that start in the ventricles instead of the atria. (nchmd.org)
  • Right Ventricular Shape Feature Quantification for Evaluation of Pulmonary Hypertension: Feasibility and Preliminary Associations With Clinical Outcome Submitted for Publication. (ucsf.edu)
  • This allowed us consider what features of contraction can and cannot be ascribed to the myosin isoforms present in the atria and ventricles. (cam.ac.uk)
  • Reduced ventricular functioning limits the ability of the ventricles to fill with blood and pump blood to the rest of the body. (wikipedia.org)
  • Both atria contract together, as do the ventricles, but atrial contraction occurs first. (medscape.com)
  • 2 Thus, diastolic evaluation is an important component of the evaluation of the patient with systolic left ventricular (LV) impairment. (bmj.com)
  • A broad spectrum of severity of impairment of cardiac function is ordinarily included in the definition of HF. (medscape.com)
  • Inhaled nitric oxide did not change right ventricular contractility, as measured by preload-recruitable stroke work. (duke.edu)
  • The beneficial effects of inhaled nitric oxide are related to alterations in right ventricular afterload and not intrinsic right ventricular contractility. (duke.edu)
  • Echocardiographic parameters can not only estimate the hemodynamic status of patients but also measure the diameter of the pulmonary artery, the size, and the overall motion status of the right ventricle to assess the right ventricular function of patients [ 13 ]. (hindawi.com)
  • Excitation-contraction coupling. (ucsd.edu)
  • Modeling cardiac excitation-contraction coupling. (ucsd.edu)
  • ECG shows biventricular pacing (double ventricular pacing spikes). (medscape.com)
  • 1) Relationships between left ventricular mechano-energetic function and underlying cellular processes, with a special emphasis on contractile and regulatory proteins and post-translational regulation of cardiac contraction (e.g., via phosphorylation or acetylation). (pitt.edu)
  • 2. The present study was designed to determine the effect of direct electrical stimulation of the left vagus nerve on left ventricular contractile state in hearts paced at 10 % above the natural rate, in anaesthetised pigs and anaesthetised human subjects undergoing open chest surgery for coronary artery bypass grafting. (ox.ac.uk)
  • The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. (uab.es)
  • The pressure-volume framework for assessing cardiac function, specifically the use of an end-systolic pressure-volume relationship (ESPVR) to assess cardiac contractile function is well-known. (justia.com)
  • In the most common phenotype, the anterior septum and contiguous anterior free wall below the aortic valve are markedly hypertrophied and thickened, with little or no hypertrophy of the left ventricular (LV) posterior wall. (msdmanuals.com)
  • Right ventricular function between patients after COVID-19 rehabilitation and healthy people was compared. (hindawi.com)
  • In summary, COVID-19 had no substantial effect on right ventricular function and better recovery in patients. (hindawi.com)
  • These findings suggest that subclinical left ventricular intolerance for volume overload, probably because of the smaller LVEDD, may exist during pregnancy in patients with a repaired ToF. (nih.gov)
  • These data suggest that a diagnosis of diastolic HF may accurately be made as a diagnosis of exclusion, 4 albeit in a highly selected population of relatively young, predominantly male patients who were scheduled to undergo cardiac catheterisation (contrasting with the large clinical population of elderly, hypertensive, predominantly female patients with HF and preserved systolic function). (bmj.com)
  • These patients present with exertional dyspnoea in the context of normal systolic function, and in this situation, symptoms may be ascribed to diastolic HF. (bmj.com)
  • Details regarding cardiac function in patients with LBBB and normal coronary arteries ( most were shown not to have coronary artery disease by angiography) were provided by Ozdemir who studied 45 cases of isolated LBBB ranging in age from 48 to 72. (blogspot.com)
  • The potentially harmful effects of long-term RV pacing may occur in patients with either preserved and reduced left ventricular (LV) systolic function. (acc.org)
  • However, we still have a group of selected patients with preserved LV function for whom the indication of CRT remains controversial. (acc.org)
  • This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. (uab.es)
  • however, virtually any asymmetric pattern of left ventricular hypertrophy can be observed, and in a small minority of patients even symmetric hypertrophy has been noted. (msdmanuals.com)
  • Pulsed-wave tissue Doppler imaging (TDI) of the left ventricular longitudinal myocardial velocity associated with atrial contraction (A'), both at the level of the interventricular septum and the LV free wall, was also used as an indicator of LA function. (openveterinaryjournal.com)
  • 4. Anatomical classifications of epithelial tissue and 2 primary functions? (fsu.edu)
  • However, insight into the histo-anatomical basis for cardiac tissue re-arrangement during contraction is limited. (ox.ac.uk)
  • Coronary microvascular function has important diagnostic and prognostic implications but routine assessment is difficult. (nih.gov)
  • 0.001) and the ratio of E to inflow velocity during atrial contraction (A), E/A (p = 0.012) was significantly lower. (scipedia.com)