• Proline isomerization greatly impacts biological signaling but is subtle and difficult to detect in proteins. (rcsb.org)
  • Our structural and kinetic data support a role for Cdc14 in the preferential dephosphorylation of proteins modified by proline-directed kinases. (rcsb.org)
  • Proline, one of the 20 naturally occurring amino acids in the body, is enriched in extracellular matrix proteins, e.g., collagen, and as such is readily available when connective tissue is broken down at sites of infection, or when a host becomes vulnerable as a result of cancerous growth or upon the onset of sarcopenia. (sciencedaily.com)
  • Proline-rich proteins (PRPs) is a class of intrinsically unstructured proteins (IUP) containing several repeats of a short proline-rich sequence. (wikipedia.org)
  • Adults with no caries neutralize these acids better than adults with severe caries, and their parotid saliva possesses longer, less fragmented basic proline rich proteins, BPRPs (Ayad et al. (umich.edu)
  • It is the high proline and glutamine content in gluten that prevents the proteins from being completely broken down by the digestive enzymes. (thegardenisland.com)
  • Prolidase is particularly important in the breakdown of collagens, a family of proteins that are rich in proline and hydroxyproline. (medlineplus.gov)
  • The intellectual disability that occurs in prolidase deficiency might result from problems in processing neuropeptides, which are brain signaling proteins that are rich in proline. (medlineplus.gov)
  • Novri Y. Kandowangko : Revision of Certificate Plagiarism by Turnitin Proline and Abscisic Acid Content in Droughted Corn Plant Inoculated with Azospirillum sp. (ung.ac.id)
  • Compatible solutes fall into 3 major groups: amino acids (e.g., proline), quaternary and tertiary onium compounds (e.g., glycine betaine, dimethylsulfoniopropionate), and polyol/small sugars (e.g., mannitol, trehalose), all of which are substances that are highly soluble in water [ 9 ]. (hindawi.com)
  • 14 ] reported that the accumulated citrulline could contribute to the protection of green tissues from the secondary oxidative stress induced under drought conditions because it behaves in vitro as a more potent hydroxyl radical scavenger than compatible solutes like mannitol, proline, and glycine betaine. (hindawi.com)
  • The water deficit in the soil provided significant increases in the concentrations of glycine betaine, nitrate, proline and aminoacids, both in the leaves and in the roots of the corn plants. (bvsalud.org)
  • Increased para-amino-isobutyric acid, leucine, and proline levels in the urine. (medscape.com)
  • The mutation (a CCG to CTG transition) at codon 82 in exon 4, resulting in a proline to leucine substitution, has not previously been reported and was not present in a control set of 60 healthy individuals. (lu.se)
  • Further weighted gene co-expression network analysis (WGCNA) uncovered that turquoise and yellow gene modules were tightly linked to antioxidant enzymes activity and ion content, respectively. (frontiersin.org)
  • Also, some TFs-hub genes were identified by WGCNA in these two modules highly positive-related to antioxidant enzymes activity and ion content. (frontiersin.org)
  • Sodium and proline contents were also measured and finally, effects of MJ and salinity interactions on all characteristics as well as relationship of antioxidant enzymes activity with proline content were investigated. (springer.com)
  • Amino acid proline content in a plant or plant part. (planteome.org)
  • The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections. (sciencedaily.com)
  • Furthermore, an elevation of antioxidant enzymes activities (superoxide dismutase, catalase, glutathione peroxydase) and proline content in association with relatively high amounts of hydrogen peroxide, thiobarbituric acid reactive substances and electrolyte leakage were observed. (unboundmedicine.com)
  • The activity of superoxide dismutase (SOD) and the concentration of chlorophyll, free proline (Pro), and malondialdehyde (MDA) of Camptotheca acuminata seedling under low temperature stress were studied. (lykxyj.com)
  • Due to this inherent characteristic, these phosphatases respond differently to enzymes that catalyze the isomerization of proline, like Ess1/Pin1. (rcsb.org)
  • In fact, Cd-stressed olive plants treated with proline showed an increase of antioxidant enzymes activities, photosynthetic activity, nutritional status, plant growth and oil content of olive fruit. (unboundmedicine.com)
  • These observations provide novel insights implicating proline metabolism as a key determinant of pathogenic fungal growth. (sciencedaily.com)
  • Iqbal N, Umar S, Khan NA, Khan MIR (2014) A new perspective of phytohormones in salinity tolerance: regulation of proline metabolism. (springer.com)
  • Compressed disc did not incorporate proline, demonstrating marked interference with protein metabolism. (cdc.gov)
  • These results support a model in which, instead of a global enhancement of downstream enzymatic activities, proline isomerases selectively boost the activity of a subset of CTD regulatory factors specific for cis-proline. (rcsb.org)
  • The team used proline as a reducing agent, potassium acetate as a base, and dimethylsulfoxide (DMSO) as the solvent. (chemistryviews.org)
  • The photosynthetic rate concomitantly with membrane stability index, potassium content, as well as free proline content was markedly increased. (springer.com)
  • Other examples include Proline-Rich 12, Proline-Rich Protein 30, and Proline-Rich Protein 21. (wikipedia.org)
  • The lack of water in plants provided a reduction in the protein and nitrate reductase contents, in leaves and roots. (bvsalud.org)
  • The Cd treatment induced substantial accumulation of Cd in both root and leaf tissues and a decrease in gas exchange, photosynthetic pigments contents, uptake of essential elements (Ca, Mg and K) and plant biomass. (unboundmedicine.com)
  • C . difficile was presumptively identified on the basis of Gram stain and detection of L-proline aminopeptidase activity (Pro Disc, Remel, Lenexa, KS, USA) and confirmed by identification of the triose phosphate isomerase gene ( 9 ). (cdc.gov)
  • The results consistently showed that strains unable to metabolize proline exhibit significantly reduced virulence properties and a clearly diminished capacity to undergo morphological transitions. (sciencedaily.com)
  • In addition, the quercetin content was increased significantly in flowers. (springer.com)
  • When cells die, their contents are released into the surrounding tissue, which could cause inflammation and lead to the skin problems seen in prolidase deficiency. (medlineplus.gov)
  • The lead author of this study Dr. Fitz Gerald S. Silao explains: "In fungal cells possessing mitochondria equipped with a full complement of energy conserving respiratory complexes, the catabolism of proline generates almost as much chemical energy (ATP) as does the catabolism of the energy-rich sugar glucose. (sciencedaily.com)
  • Dmitry Tsvelikhovsky and colleagues, The Hebrew University of Jerusalem, Israel, have developed a metal-free, easy-to-operate, proline-promoted dehydroxylation of α-ketols. (chemistryviews.org)
  • Bates L, Waldern R, Teare I (1973) Rapid determination of free proline for water stress studies. (springer.com)
  • It wasnt so crowded and Proline used to give tons of stuff away and sell their products for ~50% off. (ar15.com)
  • In the present work, citrulline accumulation under salinity and drought conditions was compared, separately in tolerant and sensitive melons, with the alterations of proline, total amino acids, and osmotic potentials. (hindawi.com)
  • We provide the chemical tools to investigate proline isomerization and its ability to selectively enhance signaling in transcription and other biological contexts. (rcsb.org)
  • Several studies have reported the ability of the lactotripeptides valine-proline- proline (VPP) and isoleucine-proline-proline (IPP) to lower systolic blood pressure (SBP), including in Japanese populations. (scirp.org)
  • The investigating team now report that proline is an important source of energy in other pathogenic Candida species, including the multidrug resistant C. auris , an emerging health threat and also a WHO critical priority fungal pathogen. (sciencedaily.com)
  • Proline plays an important role in plant response to various environmental stresses. (unboundmedicine.com)
  • Because of their nutrient content, antacids that contain calcium or magnesium are released with the DSQ data, irrespective of where they were reported. (cdc.gov)
  • Unfortunately, precise genomic structure could not be determined with certainty due to high GC content and repetitive elements which negatively impacted read mapping accuracy. (umich.edu)
  • We determine the proline isomeric preference of three CTD phosphatases: Ssu72 as cis-proline specific, Scp1 and Fcp1 as strongly trans-preferred. (rcsb.org)
  • A family of serine proteases with specificity for proline-specific cleavage of peptides that are not longer than 30 amino acids. (bvsalud.org)
  • The association of L-proline and trehalose kept ADMSC viable for 30 and 90 days of freezing, and could be an alternative as a cellular cryopreservative without toxicity and enabling the use of serial fat grafting. (bvsalud.org)
  • Strikingly, genetic dissection of the Proline UTilization (PUT) pathway and of the control mechanisms governing proline use led to the discovery that proline is toxic to cells unable to catabolize it. (sciencedaily.com)
  • Notably, mice infected with fungal cells unable to catabolize proline, e.g., cells lacking the Put2 enzyme (1-pyrroline-5-carboxylate (P5C) dehydrogenase) , showed milder illness or no symptoms at all. (sciencedaily.com)
  • In this study, we examined the effectiveness of exogenous proline (10 and 20 mM) in alleviating cadmium induced inhibitory effects in young olive plants (Olea europaea L. cv. (unboundmedicine.com)
  • Generally, it seems that proline supplementation alleviated the deleterious effects of young olive plants exposed to Cd stress. (unboundmedicine.com)
  • Although proline has long been known to trigger hyphal growth, we have recently discovered that C. albicans can use proline as a main source of energy. (sciencedaily.com)
  • Page 1 Operating and Installation Instructions ProLine Fryer To prevent accidents and machine damage, read these instructions before installation or use. (manualslib.com)
  • Tannin-binding capacity of salivary mucin is directly related to its proline content. (wikipedia.org)
  • Schedule a demo today to find out how you can access this content and similar content related to your area of the global aviation industry. (aviationweek.com)
  • The analysis of ADMSCs, after 1 and 3 months of freezing, indicated that samples treated with L-proline + trehalose showed similar viability to those preserved with DMSO and SFB ( p =0.444). (bvsalud.org)
  • Interestingly, the application of exogenous proline alleviated the oxidative damage induced by Cd accumulation. (unboundmedicine.com)
  • This content requires a subscription to one of the Aviation Week Intelligence Network (AWIN) bundles. (aviationweek.com)
  • Anyhow, just seeing if any of you all were also attending this year's Proline event to shake a hand or two and do some crawling! (ar15.com)
  • Link to all direct and indirect annotations download (limited to first 10,000) for proline content. (planteome.org)