• rats
  • In this study, we examined the cardiovascular function of anesthetized rats before, during and after being constricted by boas ( Boa constrictor ) to examine the effect of constriction on the prey's circulatory function. (biologists.org)
  • By the end of constriction (mean 6.5±1 min), rat PBP dropped 2.9-fold, f H dropped 3.9-fold, systemic perfusion pressure (SPP=PBP−CVP) dropped 5.7-fold, and 91% of rats (10 of 11) had evidence of cardiac electrical dysfunction. (biologists.org)
  • Blood drawn immediately after constriction revealed that, relative to baseline, rats were hyperkalemic (serum potassium levels nearly doubled) and acidotic (blood pH dropped from 7.4 to 7.0). (biologists.org)
  • Here, we describe a detailed surgical procedure for creating pressure overload and cardiac hypertrophy in rats by constriction of the ascending aorta using a small metallic clip. (jove.com)
  • process
  • As legless predators, snakes are unique in their ability to immobilize and kill their prey through the process of constriction, and yet how this pressure incapacitates and ultimately kills the prey remains unknown. (biologists.org)
  • In this method, cells were aspirated through a constriction channel while the cellular entry process into the constriction channel was recorded using a high speed camera and the impedance profiles at two frequencies (1 kHz and 100 kHz) were simultaneously measured by a lock-in amplifier. (mdpi.com)
  • Numerical simulations were conducted to model cellular entry process into the constriction channel, focusing on two key parameters: instantaneous aspiration length ( L instantaneous ) and transitional aspiration length ( L transitional ), which was further translated to E instantaneous . (mdpi.com)
  • model
  • An equivalent distribution circuit model for a cell travelling in the constriction channel was used to determine C specific membrane . (mdpi.com)
  • pressure
  • The intensity of pressure overload created by constriction of the ascending aorta is determined by recording the pressure gradient using trans-thoracic two dimensional Doppler-echocardiography. (jove.com)