Constitutively active selectivity protein kinase inhibitors. Medical search. Frequent questions

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Anatomy16

Cells, Cultured Cell Line Tumor Cells, Cultured Cell Line, Tumor 3T3 Cells Cell Nucleus HeLa Cells Cytosol Fibroblasts Cell Membrane Neurons PC12 Cells CHO Cells Myocardium Muscle, Smooth, Vascular Oocytes

Organisms7

Rats, Sprague-Dawley Cattle Rabbits Cricetinae Rats, Wistar Mice, Inbred C57BL Mice, Knockout

Chemicals and Drugs169

Protein Kinase Inhibitors Protein Kinase C Protein Kinases Cyclic AMP-Dependent Protein Kinases Staurosporine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Enzyme Inhibitors Protein-Serine-Threonine Kinases Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases Isoquinolines p38 Mitogen-Activated Protein Kinases Phosphatidylinositol 3-Kinases Alkaloids Indole Alkaloids Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 1 Carbazoles Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinase 3 Tetradecanoylphorbol Acetate Cyclic AMP Piperazines JNK Mitogen-Activated Protein Kinases Cyclic GMP-Dependent Protein Kinases Protein Kinase C-alpha Indoles Protein Kinase C-delta Pyridines src-Family Kinases Isoenzymes Pyrimidines Calcium AMP-Activated Protein Kinases Genistein Intracellular Signaling Peptides and Proteins Cyclin-Dependent Kinases Flavonoids Protein Kinase C-epsilon CDC2 Protein Kinase Imidazoles Protein Kinase C beta Maleimides Casein Kinase II Cyclin-Dependent Kinase Inhibitor p27 RNA, Messenger Phosphoproteins Sulfonamides Proto-Oncogene Proteins c-akt Calcium-Calmodulin-Dependent Protein Kinase Type 2 Proto-Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p21 Extracellular Signal-Regulated MAP Kinases Carrier Proteins Chromones Androstadienes Recombinant Proteins Benzamides MAP Kinase Kinase 1 Okadaic Acid Phorbol 12,13-Dibutyrate Morpholines Phorbol Esters MAP Kinase Kinase Kinases Antineoplastic Agents Casein Kinases Serine rho-Associated Kinases Adenosine Triphosphate Diglycerides Phosphoprotein Phosphatases Tyrosine p21-Activated Kinases Nitriles Cyclic AMP-Dependent Protein Kinase Type II Butadienes eIF-2 Kinase Ribosomal Protein S6 Kinases Recombinant Fusion Proteins Pyrroles Ethers, Cyclic Receptor Protein-Tyrosine Kinases Naphthalenes Receptor, Epidermal Growth Factor MAP Kinase Kinase 4 Phosphotransferases (Alcohol Group Acceptor)DNA-Binding Proteins Colforsin Cell Cycle Proteins Protamine Kinase Cyclic GMP Quinazolines Isoflavones Benzophenanthridines Aurora Kinases Phenanthridines Glycogen Synthase Kinase 3 Mitogen-Activated Protein Kinase 14 Transcription Factors Pyrazoles 2-Aminopurine Myosin-Light-Chain Kinase Cyclins Tyrphostins DNA-Activated Protein Kinase 8-Bromo Cyclic Adenosine Monophosphate Membrane Proteins CDC2-CDC28 Kinases Thiazoles 3-Phosphoinositide-Dependent Protein Kinases Creatine Kinase Proteins Threonine Peptides Thionucleotides Nuclear Proteins Phosphotyrosine Pyruvate Kinase Ribosomal Protein S6 Kinases, 90-kDa DNA Primers Diacylglycerol Kinase NF-kappa B Mitogen-Activated Protein Kinase 8 Phosphoserine Calmodulin I-kappa B Kinase MAP Kinase Kinase 2 MAP Kinase Kinase Kinase 1 Actins Oxazoles DNA RNA, Small Interfering Thymidine Kinase 1-Phosphatidylinositol 4-Kinase TOR Serine-Threonine Kinases Cyclin-Dependent Kinase Inhibitor p57 Cyclin-Dependent Kinase 2 Cyclic AMP Response Element-Binding Protein 1-Methyl-3-isobutylxanthine Tumor Necrosis Factor-alpha Epidermal Growth Factor Type C Phospholipases Cyclin-Dependent Kinase Inhibitor Proteins Kinetin Bucladesine Focal Adhesion Kinase 1 Protein Isoforms Tumor Suppressor Proteins Purines Focal Adhesion Protein-Tyrosine Kinases Insulin Amides Anthracenes Adaptor Proteins, Signal Transducing Cycloheximide Cyclic GMP-Dependent Protein Kinase Type I Oligopeptides Multienzyme Complexes Egtazic Acid Enzyme Activators MAP Kinase Kinase 6 Calcimycin MAP Kinase Kinase 3 Janus Kinase 2 Transcription Factor AP-1 Ionomycin GTP-Binding Proteins Death-Associated Protein Kinases Aurora Kinase A

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Transfection Blotting, Western Models, Biological Immunoblotting Models, Molecular Mutagenesis, Site-Directed Cloning, Molecular Inhibitory Concentration 50 Drug Design Precipitin Tests Reverse Transcriptase Polymerase Chain Reaction Electrophoresis, Polyacrylamide Gel Microscopy, Fluorescence Peptide Mapping

Phenomena and Processes46

Phosphorylation Enzyme Activation MAP Kinase Signaling System Signal Transduction Kinetics Amino Acid Sequence Dose-Response Relationship, Drug Transfection Protein Binding Substrate Specificity Apoptosis Mutation Binding Sites Base Sequence Cell Division Time Factors Cell Cycle Gene Expression Regulation Protein Structure, Tertiary Transcription, Genetic Structure-Activity Relationship Down-Regulation Cell Proliferation Sequence Homology, Amino Acid Cell Survival Gene Expression Regulation, Enzymologic Second Messenger Systems Biological Transport Up-Regulation Gene Expression Inhibitory Concentration 50 Drug Synergism Cell Differentiation Molecular Weight Promoter Regions, Genetic Enzyme Induction Mitosis Transcriptional Activation Protein Transport Protein Conformation Drug Resistance, Neoplasm Cell Movement Catalytic Domain Catalysis G1 Phase Membrane Potentials

Disciplines and Occupations1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Protein Kinase Inhibitors Protein Kinase C Protein Kinases Cyclic AMP-Dependent Protein Kinases Staurosporine Phosphorylation 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Enzyme Inhibitors Protein-Serine-Threonine Kinases Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases Isoquinolines p38 Mitogen-Activated Protein Kinases Phosphatidylinositol 3-Kinases Enzyme Activation Alkaloids MAP Kinase Signaling System Signal Transduction Indole Alkaloids Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 1 Carbazoles Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinase 3 Cells, Cultured Tetradecanoylphorbol Acetate Cyclic AMP Cell Line Piperazines JNK Mitogen-Activated Protein Kinases Cyclic GMP-Dependent Protein Kinases Molecular Sequence Data Protein Kinase C-alpha Indoles Kinetics Protein Kinase C-delta Pyridines src-Family Kinases Amino Acid Sequence Isoenzymes Pyrimidines Calcium AMP-Activated Protein Kinases Genistein Intracellular Signaling Peptides and Proteins Cyclin-Dependent Kinases Dose-Response Relationship, Drug Flavonoids Protein Kinase C-epsilon CDC2 Protein Kinase Imidazoles Protein Kinase C beta Maleimides Casein Kinase II Transfection Protein Binding Substrate Specificity Blotting, Western Cyclin-Dependent Kinase Inhibitor p27 RNA, Messenger Phosphoproteins Tumor Cells, Cultured Apoptosis Mutation Sulfonamides Proto-Oncogene Proteins c-akt Cell Line, Tumor Calcium-Calmodulin-Dependent Protein Kinase Type 2 Proto-Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p21 Extracellular Signal-Regulated MAP Kinases Carrier Proteins Chromones Binding Sites Androstadienes Recombinant Proteins Benzamides MAP Kinase Kinase 1 Okadaic Acid Phorbol 12,13-Dibutyrate Morpholines Phorbol Esters Base Sequence Cell Division MAP Kinase Kinase Kinases Antineoplastic Agents Casein Kinases Serine Time Factors rho-Associated Kinases Adenosine Triphosphate Rats, Sprague-Dawley Diglycerides Phosphoprotein Phosphatases Tyrosine Cell Cycle p21-Activated Kinases Nitriles Cyclic AMP-Dependent Protein Kinase Type II Butadienes

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