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  • fibrinogen
  • 6. An elastin containing composition according to claim 1, further comprising at least one additive selected from the group consisting of collagen, thiourea, cellulose derivatives, calcium alginate, sodium ethylmercrylthiosalicylate, FVIII complex (antihemophilic A), the latter containing about 10 to 15 g/l of fibrinogen and about 2 to 4 g/l of fibronectin, von Willebrand factor, thrombospondin and laminin. (google.co.uk)
  • elastase
  • As a type of enzyme inhibitor, it protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 0.9-2.3 g/L (in the US the reference range is expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation. (wikipedia.org)
  • When the blood contains inadequate amounts of A1AT or functionally defective A1AT (such as in alpha-1 antitrypsin deficiency), neutrophil elastase is excessively free to break down elastin, degrading the elasticity of the lungs, which results in respiratory complications, such as chronic obstructive pulmonary disease, in adults. (wikipedia.org)
  • blood vessels
  • Third degree burns are the most severe because the damage extends past the upper layers of skin to the sensitive subcutaneous tissue, destroying nerves, blood vessels, and other dermal components. (blausen.com)
  • Elastin serves an important function in arteries as a medium for pressure wave propagation to help blood flow and is particularly abundant in large elastic blood vessels such as the aorta. (wikipedia.org)
  • It surrounds blood vessels and nerves and penetrates with them even into the small spaces of muscles, tendons, and other tissues. (wikipedia.org)
  • Nearly every epithelium rests on a layer of areolar tissue, whose blood vessels provide the epithelium with nutrition, waste removal, and a ready supply of infection-fighting leukocytes in times of need. (wikipedia.org)
  • elasticity
  • The majority of these changes are a result of the soft tissues of the face losing its elasticity and volume. (bmc.org)
  • synthesis
  • These supplies are necessary to carry out such metabolic functions as cellular respiration, melanin pigment and connective tissue synthesis, iron metabolism, free radical defense, gene expression, and the normal functioning of the heart and immune systems in infants. (wikipedia.org)
  • amino acids
  • The macrophage cathepsins D and B degraded all the matrix components at an optimum pH of 5.5 and acted with the secreted neutral proteinases to degrade the connective tissue macromolecules to amino acids and oligopeptides. (rupress.org)
  • bone
  • Tendons are bands of fibrous tissue that connect muscle to bone. (blausen.com)
  • Any of a family of 30-38-kD homodimeric growth factors involved in bone and cartilage formation, which provide morphogenetic signals that guide normal tissue architecture. (thefreedictionary.com)
  • At the sides of the chest, the breast tissue can extend into the axilla (armpit), and can reach as far to the back as the latissimus dorsi muscle, extending from the lower back to the humerus bone (the longest bone of the upper arm). (wikipedia.org)
  • Osteogenesis imperfecta (brittle bone disease) - caused by poor quality collagen, or insufficient amounts of normal collagen (primarily type I), necessary for healthy, strong bones and certain other connective tissues. (wikipedia.org)
  • macrophages
  • Conditioned medium from resident and inflammatory macrophages, containing mixtures of the secreted proteinases, degraded the glycoprotein and elastin components of the matrices. (rupress.org)
  • histology
  • The terms "collagen diseases" was coined originally to denote a group of disorders which showed common features such as multisystem involvement, fibrinoid degeneration of connective tissue demonstrable on histology and caused by immunological processes. (hubpages.com)
  • gene
  • Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. (wikipedia.org)
  • In humans, elastin is encoded by the ELN gene. (wikipedia.org)
  • Cutis laxa and Williams syndrome have elastic matrix defects that have been directly associated with alterations in the elastin gene. (wikipedia.org)
  • proline
  • The long version of PC5S is expressed in various tissues and is significant for its ability to synthesize proline from glutamate. (wikipedia.org)