• hepatocellular carcinoma
  • There is no consensus about the optimal treatment of hepatocellular carcinoma (HCC) with cirrhotic portal hypertension, While this group of patients are classified as hepatectomy contraindication according to guidelines from National Comprehensive Cancer Network (NCCN) and American Association for the Study of Liver Diseases (AASLD). (clinicaltrials.gov)
  • With improvement of surgical technique, preoperative evaluation, and perioperative management,especially the Precise Hepatectomy Technique, more and more studies confirmed the safety of surgical intervention to hepatocellular carcinoma (HCC) patients with cirrhotic portal hypertension.However, most of the previous studies were either retrospective or with small samples. (clinicaltrials.gov)
  • The investigators project is a prospective randomized controlled trial, planning to compare the safety, efficacy and quality of life between precise hepatectomy and combined interventional treatment on hepatocellular carcinoma (HCC) with cirrhotic portal hypertension, to make a further understanding of optimal strategy. (clinicaltrials.gov)
  • outcomes
  • The Heart Outcomes and Prevention Evaluation trial seemed to show ramipril possessed cardioprotective qualities which extended beyond its qualities as an antihypertensive. (wikipedia.org)
  • mitral valve
  • The mitral valve controls the blood flow from the lungs back into the left side of the heart, to be pumped back out through the rest of the body. (wikipedia.org)
  • diabetes
  • The Baker Heart and Diabetes Institute, commonly known as the Baker Institute, is an Australian independent medical research institute headquartered in Melbourne, Victoria. (wikipedia.org)
  • kidneys
  • Other than the kidneys, liver and heart are the most commonly involved organs. (wikipedia.org)
  • β1-adrenergic receptors are located mainly in the heart and in the kidneys. (wikipedia.org)
  • Beta receptors are found on cells of the heart muscles, smooth muscles, airways, arteries, kidneys, and other tissues that are part of the sympathetic nervous system and lead to stress responses, especially when they are stimulated by epinephrine (adrenaline). (wikipedia.org)
  • commonly
  • Bisoprolol, marketed under the tradename Zebeta among others, is a medication most commonly used for heart diseases. (wikipedia.org)
  • include
  • Common side effects by mouth include tiredness, slow heart beat, itchiness, and shortness of breath. (wikipedia.org)
  • Common side effects include headache and fast heart rate. (wikipedia.org)
  • Very common (>10% frequency) side effects include headache, high heart rate, and palpitations. (wikipedia.org)
  • high
  • In this study, the investigators hypothesize that a modification in the composition of the endogenous digestive microflora by oral bacteriotherapy with high potency probiotic preparations could be a safe way to regulate the portal pressure. (clinicaltrials.gov)
  • mainly
  • Bisoprolol is cardioprotective because it selectively and competitively blocks catecholamine (adrenalin) stimulation of β1 adrenergic receptors (adrenoreceptors), which are mainly found in the heart muscle cells and heart conduction tissue (cardiospecific), but also found in juxtaglomerular cells in the kidney. (wikipedia.org)
  • The effects of the drug are limited to areas containing β1 adrenoreceptors, which is mainly the heart and part of the kidney. (wikipedia.org)
  • medication
  • Most of the research supporting the use of thiazide diuretics in hypertension was done using chlorthalidone, a different medication in the same class. (wikipedia.org)