• On Tuesday, Sept. 12, 2023 advisers to the Food and Drug Administration said that a different ingredient, phenylephrine, is ineffective at relieving nasal congestion. (wreg.com)
  • Modern studies, when well conducted, are not showing any improvement in congestion with phenylephrine," said Dr. Mark Dykewicz, an allergy specialist at the Saint Louis University School of Medicine. (wreg.com)
  • The FDA assembled its outside advisers to take another look at phenylephrine, which became the main drug in over-the-counter decongestants when medicines with an older ingredient - pseudoephedrine - were moved behind pharmacy counters. (wreg.com)
  • That would likely force consumers to switch to the behind-the-counter pseudoephedrine products or to phenylephrine-based nasal sprays and drops. (wreg.com)
  • This week's two-day meeting was prompted by University of Florida researchers who petitioned the FDA to remove most phenylephrine products based on recent studies showing they failed to outperform placebo pills in patients with cold and allergy congestion. (wreg.com)
  • Going back to 2015, there was a citizen's petition to remove phenylephrine from the over-the-counter drugs in the U.S. Back then, researchers had studies showing that as an oral decongestant, it's completely ineffective. (krvs.org)
  • That would likely force consumers to switch to the behind-the-counter pills or to nasal sprays and drops that contain phenylephrine, which are not under review. (cp24.com)
  • Additionally, three larger, rigorously conducted studies published since 2016 showed no difference between phenylephrine medications and placebos for relieving congestion. (cp24.com)
  • These tablets contain diphenhydramine, an antihistamine ingredient that may reduce allergy symptoms, and phenylephrine, which may reduce sinus congestion. (healthline.com)
  • These coated tablets contain the decongestant ingredient phenylephrine along with the pain reliever ibuprofen. (healthline.com)
  • But FDA reviewers said their latest assessment reflects new testing insights into how quickly phenylephrine is metabolized when taken by mouth, leaving only trace levels that reach nasal passages to relieve congestion. (fox35orlando.com)
  • The group's negative opinion opens the door for the FDA to pull phenylephrine from a federal list of decongestants deemed effective for over-the-counter pills and liquids. (statedpodcast.com)
  • This comes after the 16-member panel with the FDA said that a commonly used dose of the decongestant phenylephrine doesn't work. (klfy.com)
  • Phenylephrine became the main drug in over-the-counter decongestants when medicines with an older ingredient, pseudoephedrine, were moved behind pharmacy counters. (klfy.com)
  • Experts said the products with phenylephrine are ineffective because the stomach ends up digesting the medicine, and by the time it reaches the nasal, there is not much of an impact. (klfy.com)
  • An FDA panel recently declared that the over-the-counter decongestant phenylephrine does not work. (milberg.com)
  • That's the damning conclusion of a Food and Drug Administration (FDA) panel about phenylephrine decongestants, whose efficacy have been questioned since they were introduced in the early 2000s. (milberg.com)
  • Phenylephrine was approved by the FDA for over-the-counter use in 1976 and became the main ingredient in OTC decongestants in 2006. (milberg.com)
  • Fast-forward to the second phenylephrine FDA advisory committee in 2023, where a panel voted 16-0 that the oral decongestant is clinically ineffective in reducing congestion symptoms. (milberg.com)
  • Nonetheless, the complaint continues, CVS represents its PE products as "MAXIMUM STRENGTH," which is misleading to consumers because phenylephrine is ineffective, and products with effective nasal decongestants, including those containing pseudoephedrine, are available. (milberg.com)
  • Phenylephrine is a decongestant which helps relieve nasal congestion. (patientassistance.com)
  • Symptoms may be mild, or the congestion may be so great that the only relief is to overuse (abuse) topical decongestants such as oxymetazoline or phenylephrine. (medscape.com)
  • Cold, allergy, and hay fever-related nasal irritation are all treated with phenylephrine. (prescriptiongiant.com)
  • The drug phenylephrine belongs to the group of drugs known as nasal decongestants. (prescriptiongiant.com)
  • All told, decongestants with phenylephrine account for roughly $1.8 billion in annual sales, according to an FDA report . (cbsnews.com)
  • The combination of oral phenylephrine with the antihistamine diphenhydramine is contained in several popular cold medicines and decongestants, such as Benadryl Allergy Plus Congestion, Robitussin Night Time Cough and Cold, and Delsym Children's Night Time Cough and Cold. (dailymail.co.uk)
  • In 2007, pharmacy professors at the University of Florida put forth a petition pressing the FDA to review whether a 10 milligram phenylephrine pill worked as a decongestant. (dailymail.co.uk)
  • Decongestants decrease swelling in the nose, which may ease symptoms associated with postnasal drip, such as a runny nose . (medicalnewstoday.com)
  • Upper respiratory infections URIs are common ailments that can leave you feeling miserable with symptoms like a runny nose, sore throat, cough, and congestion. (electric-weekend.com)
  • Decongestants and antihistamines can help alleviate nasal congestion and runny nose. (electric-weekend.com)
  • Your doctor may also recommend a topical nasal steroid spray, an antihistamine or decongestant to reduce congestion, runny nose, and pressure symptoms. (kidshealth.org)
  • Symptoms may include a cough, a mild sore throat, nasal congestion, a runny nose or sneezing, and sometimes a fever. (healthlinkbc.ca)
  • Nasal congestion and discharge (a runny nose) are extremely common problems that commonly occur together but occasionally occur alone. (msdmanuals.com)
  • Your health care provider may suggest saline rinses to ease nasal congestion or antihistamines to relieve a runny nose, sneezing, and itchy eyes. (medlineplus.gov)
  • Over-the-counter (OTC) sinus decongestants may be able to offer temporary relief from your symptoms. (healthline.com)
  • If you're having trouble breathing due to cold, flu, or allergies, sinus decongestants are designed to relieve your symptoms and help you carry on with your day. (healthline.com)
  • You put all of that together, it's a recipe for nasal allergy symptoms, and it would be that way until almost Christmas. (klfy.com)
  • Each tablet contains 240 mg of pseudoephedrine HCl, a nasal decongestant, and relieves symptoms for up to 24 hours. (sudafed.com)
  • 10,11 Clinically, patients will experience a prolongation of symptoms such as sneezing and rhinorrhea, but the most predominant manifestation is nasal congestion that is often severe and long-lasting. (uspharmacist.com)
  • 5 Episodic AR describes allergic nasal symptoms in patients who have sporadic exposure to aeroallergens that are not typically encountered in their usual indoor or outdoor environments. (uspharmacist.com)
  • Symptoms of turbinate dysfunction range from total nasal obstruction to mild congestion and/or rhinorrhea. (medscape.com)
  • Antihistamines and nasal corticosteroid sprays are 2 types of medicine that work well for allergy symptoms. (medlineplus.gov)
  • Normal saline (saltwater) sprays and irrigations are available over the counter and are safe and effective at washing the nose and easing many nasal and sinus symptoms. (kidshealth.org)
  • Patients with intermittent symptoms are often treated adequately with oral antihistamines, decongestants, or both as needed. (medscape.com)
  • All are efficacious in controlling symptoms of allergic rhinitis (ie, sneezing, rhinorrhea, itching) but do not significantly improve nasal congestion. (medscape.com)
  • Some of the most common symptoms of sinusitis are pain, tenderness, nasal congestion. (msdmanuals.com)
  • In people with nasal congestion and discharge, certain symptoms and characteristics are cause for concern. (msdmanuals.com)
  • Acute nasal symptoms are troublesome for patients. (bvsalud.org)
  • Acute nasal symptoms include rhinorrhoea, sneezing, nasal itch and congestion. (bvsalud.org)
  • Because topical nasal decongestants provide rapid and dramatic relief from these symptoms, especially nasal congestion, they are frequently used and abused by patients. (bvsalud.org)
  • FILE - Sudafed and other common nasal decongestants containing pseudoephedrine display behind the counter at a pharmacy. (komonews.com)
  • FILE - Sudafed and other common nasal decongestants containing pseudoephedrine are on display behind the counter at Hospital Discount Pharmacy in Edmond, Okla., Jan. 11, 2005. (wreg.com)
  • Each tablet contains 240 mg of pseudoephedrine HCl, a nasal decongestant for powerful 24-hour symptom relief. (sudafed.com)
  • The Food and Drug Administration (FDA) has placed restrictions on pseudoephedrine , the active ingredient in many decongestants, because people can convert it to methamphetamine . (medicalnewstoday.com)
  • If pseudoephedrine is the active ingredient in a decongestant, the standard dosage for adults is one 60 mg tablet up to four times daily. (medicalnewstoday.com)
  • Decongestants containing pseudoephedrine stimulate certain receptors in the central nervous system that increase blood pressure . (medicalnewstoday.com)
  • Pseudoephedrine is used to relieve nasal congestion caused by colds, allergies, and hay fever. (medlineplus.gov)
  • Pseudoephedrine is in a class of medications called nasal decongestants. (medlineplus.gov)
  • Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. (drugs.com)
  • Pseudoephedrine was previously the oral decongestant of choice for drug manufacturers. (milberg.com)
  • Drugmakers also market a separate class of nasal decongestants containing pseudoephedrine (PSE). (cbsnews.com)
  • The key ingredient in a wide variety of over-the-counter oral decongestants has been thought to be ineffective for years. (dailymail.co.uk)
  • Limit use of nasal decongestant spray to 3 days. (healthtap.com)
  • Decongestants and nasal spray don't work. (healthtap.com)
  • He said nasal spray is the best option to use as the flu and cold season nears. (klfy.com)
  • I do know very conclusively that nasal spray works better than any antihistamine or oral decongestant for helping a congested nose," Prather said. (klfy.com)
  • According to research from 2019 , topical medications, such as a nasal spray, allow people to apply a higher concentration of medication directly to the receptor site. (medicalnewstoday.com)
  • Spray with nasal saline several times per day. (medlineplus.gov)
  • Studies show that it works in nasal spray form. (dailymail.co.uk)
  • Children can nose and nasal congestion, a decongestant nasal spray have lasting, thick nasal discharge for a long time without might make you feel better. (folkhalsomyndigheten.se)
  • Your provider may also suggest a nasal steroid spray. (medlineplus.gov)
  • But he says the markets would adjust, and the good news is that there are other over-the-counter medicines that are effective as nasal decongestants, including nasal sprays, so people would have alternative options, A. (krvs.org)
  • Nose sprays/steam/decongestants no help. (healthtap.com)
  • You can buy decongestant nasal sprays that relieve stuffiness or congestion without a prescription. (medlineplus.gov)
  • Topical azelastine and olopatadine are nasal sprays antihistamines that effectively reduce sneezing, itching, and rhinorrhea but also effectively reduces congestion. (medscape.com)
  • People who use nasal decongestant sprays for more than 3 to 5 days often experience significant rebound congestion (the return of congestion that is worse than before) when the effects of the decongestant wear off. (msdmanuals.com)
  • Those original versions of Sudafed and other medicines remain available without a prescription, but they're less popular and account for about one-fifth of the $2.2 billion market for oral decongestants. (wreg.com)
  • These original versions of Sudafed and other medications remain available without a prescription, but are less popular and represent about a fifth of the $2.2 billion market for oral decongestants. (someviral.com)
  • Drugs like Sudafed, made by pharmaceutical company Johnson & Johnson, are part of a roughly $2.2 billion market for oral decongestants. (cbsnews.com)
  • TUKOL Cough & Congestion Treatment, Cough Suppressant and Nasal Decongestant, Multi-Symptom Cold. (johnharvards.com)
  • The leading decongestant used by millions of Americans looking for relief from a stuffy nose is likely no better than a dummy pill, according to government experts who reviewed the latest research on the long-questioned drug ingredient. (komonews.com)
  • Nose congestion/sore throat/sweating for 13 days. (healthtap.com)
  • and for children: antihistamines, decongestants for clearing the nose, or combinations of these and leukotriene inhibitors for allergy and asthma. (wikipedia.org)
  • Dilated blood vessels can cause nasal congestion (stuffy nose). (drugs.com)
  • Of the 1211 patients with the most severe/extreme Nasal Obstruction Symptom Evaluation (NOSE) scale scores (55 or above), the prevalences were 73%, 80%, and 77%, respectively. (medscape.com)
  • The medicine works by shrinking the dilated blood vessels in the nose, relieving nasal and sinus congestion. (dailymail.co.uk)
  • Decongestants may improve nasal congestion in sinus infections. (wikipedia.org)
  • That could leave consumers scrambling to find alternative treatments for relief from nasal congestion and drugmakers hurrying to devise new drug formulations. (cbsnews.com)
  • The FDA recommends taking 10 milligrams of this non-prescription decongestant every four hours for temporary relief from nasal congestion. (dailymail.co.uk)
  • Humidify the Air - Using a humidifier or vaporizer can add moisture to the air, which can help relieve nasal congestion and soothe a sore throat. (electric-weekend.com)
  • It is recommended to drink plenty of fluids (6-8 glasses a day) to help relieve congestion. (patientassistance.com)
  • 10,11 These newly released mediators bind to nasal receptors, causing many of the manifestations of AR within minutes of exposure, which include nasal itching, sneezing, rhinorrhea, and some degree of nasal congestion. (uspharmacist.com)
  • Daily use of an antihistamine, decongestant, or both can be considered either instead of or in addition to nasal steroids. (medscape.com)
  • Decongestant ingredients work by dilating your blood vessels to relieve pressure in your sinuses. (healthline.com)
  • It works by causing narrowing of the blood vessels in the nasal passages. (medlineplus.gov)
  • Tried antihistamines and decongestants with little to no avail. (healthtap.com)
  • The term encompasses a broad array of drugs, including analgesics, antihistamines and decongestants, among many others. (wikipedia.org)
  • Antihistamines and decongestants may also slow breast milk production. (cigna.com)
  • Antihistamines and decongestants may slow breast milk production. (everydayhealth.com)
  • It may lead to blocked nasal passages that cause you to breathe through your mouth. (healthlinkbc.ca)
  • It works by drying up the nasal passages. (medlineplus.gov)
  • These tablets aren't intended to clear the flu or a cold, so it's important to only take them if your sinus congestion occurs due to allergies. (healthline.com)
  • https://www.medshopexpress.com/nexafed-nasal-decongestant-30-mg-tablets-24-tab For the temporary relief of nasal congestion due to the common cold, hay fever or other upper respiratory allergies. (medshopexpress.com)
  • For the temporary relief of nasal congestion due to the common cold, hay fever or other upper respiratory allergies. (medshopexpress.com)
  • Removing popular over-the-counter medications from the market would force some people "to find time to seek help from a pharmacist, doctor or clinic for an oral decongestant for a minor ailment they could otherwise self-treat," the group said in a statement before the determination was made. (cbsnews.com)
  • He had a similar presentation a year ago that resolved after treatment with a variety of medications, including decongestants, nasal steroids, and antibiotics. (medscape.com)
  • Nasal decongestants, in topical or oral form, are some of the most effective drugs available for reducing congestion of the turbinate mucosa. (medscape.com)
  • Some antihistamines include decongestants, which can reduce congestion, but those medicines are not for everyone. (medlineplus.gov)
  • A 21-year-old college student presents with 7 days of sinus pressure, nasal congestion, coryza, itchy/watery eyes, and a scratchy sensation in his throat. (medscape.com)
  • If nasal congestion (stuffiness) from a common cold or allergies prevents sinuses from draining as they should, bacteria can become trapped inside them, leading to bacterial sinusitis . (kidshealth.org)
  • The decongestant in your favorite OTC medication doesn't work any better than a placebo. (milberg.com)
  • In 2015, a study sponsored in part by the New Jersey-based pharmaceutical company Merck & Co found that the the 10 milligram dose, as well as 20, 30, or 40 milligram doses were 'not significantly better than placebo at relieving nasal congestion' in a sample of 539 adults. (dailymail.co.uk)
  • Allergic rhinitis is due to environmental allergens that come in contact with the nasal membranes, causing an inflammatory reaction and resultant congestion and increased drainage. (medscape.com)
  • If adults do not see them do this, the first sign may be a foul-smelling nasal discharge due to infection and irritation from the foreign object. (msdmanuals.com)
  • People with vasomotor rhinitis have a recurrent watery nasal discharge that occurs without any known triggers. (msdmanuals.com)
  • Not all episodes of nasal congestion and discharge require immediate evaluation by a doctor. (msdmanuals.com)
  • People who have nasal congestion and discharge but no warning signs should call their doctor. (msdmanuals.com)
  • usually experience thick nasal discharge that lasts for There is no medicine that can cure a cold. (folkhalsomyndigheten.se)
  • Steam Inhalation - Inhaling steam can help ease congestion by loosening mucus and soothing irritated airways. (electric-weekend.com)
  • AR is an immunoglobulin E - mediated inflammatory response of the nasal mucous membranes and upper respiratory tract following exposure to aeroallergens that the patient has been previously sensitized to. (uspharmacist.com)
  • Guidance for indications, choice of most efficacious decongestant and recommendations for limiting side effects are thus essential to be imparted to patients by doctors. (bvsalud.org)
  • Nasal congestion is the most common symptom associated with turbinate dysfunction. (medscape.com)
  • CVS, a leading manufacturer of PE oral decongestants, "knew or should have known of the same scientific literature reviewed by the FDA," according to Milberg's class action complaint . (milberg.com)
  • Many patients have tried over-the-counter (OTC) oral decongestants with limited success. (medscape.com)
  • Vasomotor is a term that indicates the neurovascular control of the nasal membranes. (medscape.com)